Abstract:
:A series of thirty-eight cases of congenital nevocellular nevi were excised and studied histologically. Depending on the extent of nevoid cell dermal infiltration, four histologic patterns were observed: diffuse or patchy infiltration of the upper dermis alone, or diffuse or patchy infiltration of the upper and deep dermis with nevoid cells in or below the lower one third of the reticular dermis. Nevoid cells extended into the deepest reticular dermis in only 37% of these patients. There was no significant correlation between the four histologic patterns and age, sex, location, or lesion size. Two cases recurred after surgery but none underwent malignant change. The patients who developed recurrent nevi in the surgical site postexcision manifested the diffuse upper and deep dermal pattern of nevoid cell infiltration. We interpret this observation as due to incomplete excision of the primary lesion, reflecting the difficulty of removing congenital nevi with this histologic pattern. We conclude from this study that: (1) congenital nevocellular nevi show at least four typical histologic patterns; (2) the nevoid cells of congenital nevi do not necessarily extend into the deep dermis; and (3) of the four histologic patterns seen in congenital nevi, that one showing diffuse and deep placement of nevoid cells on biopsy requires more aggressive excision to prevent recurrence.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Stenn KS,Arons M,Hurwitz Sdoi
10.1016/s0190-9622(83)70146-5subject
Has Abstractpub_date
1983-09-01 00:00:00pages
388-93issue
3eissn
0190-9622issn
1097-6787pii
S0190-9622(83)70146-5journal_volume
9pub_type
杂志文章abstract::A systematic, uniform evaluation of 102 patients with, or at risk for, neurofibromatosis has shown that café au lait spots (CLS), even in large numbers, may not be sufficient to diagnose this disorder, and that several other dermatologic features may provide clues to its pathogenesis. These features include pruritus a...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:
更新日期:1980-08-01 00:00:00
abstract:BACKGROUND:Methyldibromoglutaronitrile (MDGN) is a component of Euxyl K400, a preservative used in many skin care products in Europe. MDGN has been used in skin care products in the United States for the last 5 years. Contact allergy from MDGN has been reported from Europe. OBJECTIVE:The purpose of this study was to d...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(98)70589-4
更新日期:1998-06-01 00:00:00
abstract::The Cosmetic Ingredient Review (CIR) program was established in 1976 by the Cosmetics, Toiletry, and Fragrance Association, with the support of the Food and Drug Administration (FDA) and the Consumer Federation of America (CFA). CIR performs independent, expert reviews to determine if ingredients used in cosmetics are...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2004.07.066
更新日期:2005-01-01 00:00:00
abstract::In patients with psoriasis, there is an increased availability of drugs for treatment. However, there are important questions about drug safety for mothers with psoriasis and their fetuses. Currently, there are limited safety data for many of the medications used. In this article, we review current pregnancy risk info...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2008.03.018
更新日期:2008-08-01 00:00:00
abstract:BACKGROUND:Necrobiotic xanthogranuloma (NXG) is a rare histiocytic disorder of unknown origin. OBJECTIVE:We conducted an investigation of skin biopsy specimens from 7 patients with NXG for the presence of Borrelia by focus-floating microscopy. METHODS:Focus-floating microscopy is a recently described, modified immuno...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2007.05.016
更新日期:2007-12-01 00:00:00
abstract:BACKGROUND:Digital dermoscopic image analysis of pigmented skin lesions (PSLs) has become increasingly popular, despite its unclear clinical utility. Unbiased, high-powered studies investigating the efficacy of commercially available systems are limited. OBJECTIVE:To investigate the diagnostic performance of the FotoF...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2017.01.049
更新日期:2018-05-01 00:00:00
abstract:BACKGROUND:The negative pigment network (NPN) is seen as a negative of the pigmented network and it is purported to be a melanoma-specific structure. OBJECTIVES:We sought to assess the frequency, sensitivity, specificity, and odds ratios (ORs) of NPN between melanoma cases and a group of control lesions. METHODS:Digi...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2012.08.012
更新日期:2013-04-01 00:00:00
abstract::Infections with mycobacteria are of importance in the differential diagnosis of skin lesions in immunocompromised patients. We report the case of a human immunodeficency virus (HIV)-infected patient who presented with an annular plaque as cutaneous manifestation of Mycobacterium haemophilum. Improvement of the immunol...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2000.102455
更新日期:2000-11-01 00:00:00
abstract::A 9-year-old girl with systemic lupus erythematosus developed bullous eruption. Histopathologic examination showed subepidermal blistering and immunoglobulins (IgG, IgM, IgA) and complement components (C1q, C3) deposited linearly at the basement membrane zone. IgG in this patient's serum bound to the dermal side of 1 ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(98)70472-4
更新日期:1998-05-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2007.02.007
更新日期:2007-08-01 00:00:00
abstract::Hyperpigmentation of the skin is often refractory to conventional therapies, but has significant cosmetic implications if located on visible areas. Because laser systems are capable of removing pigment deposits caused by selective photothermolysis, we addressed the issue of whether the Q-switched ruby laser could be a...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2000.105555
更新日期:2000-08-01 00:00:00
abstract:BACKGROUND:Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus (CLE). Although new recommendations exist for hydroxychloroquine dosing, there is still uncertainty about the dosage that will elicit a satisfactory response in CLE while limiting adverse effects, specifically retinopathy. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2019.07.027
更新日期:2020-03-01 00:00:00
abstract::Levels of IgE antibodies to Staphylococcus aureus and Staphylococcus epidermidis were determined in eleven patients with typical atopic dermatitis, with no history of furuncles or severe staphylococcal infection. Increased IgE binding to S. aureus but not to S. epidermidis was observed. Fifteen patients with hyperimmu...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(82)80017-0
更新日期:1982-07-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2017.03.018
更新日期:2017-08-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(92)70148-9
更新日期:1992-07-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(99)70487-1
更新日期:1999-02-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2005.10.046
更新日期:2006-03-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2018.11.015
更新日期:2019-03-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(98)70196-3
更新日期:1998-05-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(95)90291-0
更新日期:1995-12-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2019.03.030
更新日期:2019-08-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2001.106348
更新日期:2001-02-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
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更新日期:2010-09-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(85)70125-9
更新日期:1985-06-01 00:00:00
abstract:BACKGROUND:Some patients with pemphigus vulgaris (PV) have mucous membrane erosions with minimal skin involvement (mucosal dominant type), and others show extensive skin blisters and erosions in addition to mucous membrane involvement (mucocutaneous type). Patients with pemphigus foliaceus (PF) show only skin involveme...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(99)70183-0
更新日期:1999-02-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(92)70240-g
更新日期:1992-11-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(89)70274-7
更新日期:1989-10-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(99)70365-8
更新日期:1999-08-01 00:00:00
abstract:BACKGROUND:A radiofrequency-controlled electrosurgical device (ESD) has been adapted for skin peeling. A high-voltage, low-amperage current converts an irrigant into an ionized vapor, causing molecular dissociation and superficial damage in adjacent tissue. OBJECTIVE:We compared the clinical and histologic effects of ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mjd.2001.109856
更新日期:2001-03-01 00:00:00
abstract::Leiomyosarcoma is a rare tumor usually treated by wide local excision. We present a case of primary leiomyosarcoma of the skin on the anterior aspect of the chest wall treated by Mohs micrographic surgery. This is only the second reported case so treated. The patient has remained recurrence-free for 30 months. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(89)70322-4
更新日期:1989-11-01 00:00:00