The role of specimen banking in risk assessment.

abstract：:The Centers for Disease Control and Prevention recommend that local public health agencies use local data to identify children at risk for lead exposure to ensure that they receive preventive services. The objective of this study was to demonstrate the usefulness of a geographic information system (GIS) in identifying...

journal_title：Environmental health perspectives

authors： Reissman DB,Staley F,Curtis GB,Kaufmann RB

更新日期：2001-01-01 00:00:00

abstract：:In this study, we determined the biologic activity of dichloromethane-extracted particulate matter < 10 micro m in aerodynamic diameter (PM10) obtained from filters at three sites in the Paso del Norte airshed, which includes El Paso, Texas, USA; Juarez, Chihuahua, Mexico, and Sunland Park, New Mexico, USA. The extrac...

journal_title：Environmental health perspectives

authors： Arrieta DE,Ontiveros CC,Li WW,Garcia JH,Denison MS,McDonald JD,Burchiel SW,Washburn BS

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:Exposure to transportation noise is widespread and has been associated with obesity in some studies. However, the evidence from longitudinal studies is limited and little is known about effects of combined exposure to different noise sources. OBJECTIVES:The aim of this longitudinal study was to estimate the...

journal_title：Environmental health perspectives

authors： Pyko A,Eriksson C,Lind T,Mitkovskaya N,Wallas A,Ögren M,Östenson CG,Pershagen G

更新日期：2017-11-20 00:00:00

abstract：:The reported incidence of acute respiratory illness in families exposed to different concentrations of air pollution was studied during two consecutive school years. The purpose of the study was to determine the effect of increased exposure to sulfur dioxide and suspended particulate matter. In each of four study comm...

journal_title：Environmental health perspectives

authors： Love GJ,Lan SP,Shy CM

更新日期：1982-04-01 00:00:00

abstract：:Antisera elicited in rabbits were used in radioimmunoassay (RIA) and enzyme-linked immunosorbent assay (ELISA) to determine femtomole quantities of deoxyguanosin-(8-yl)-acetylaminofluorene (dg-8-AAF) and deoxyguanosin-(8-yl)-aminofluorene (dg-8-AF). These adducts have been monitored in liver and kidney DNA of male Wis...

journal_title：Environmental health perspectives

authors： Poirier MC,True B,Laishes BA

更新日期：1983-03-01 00:00:00

abstract：:The capacity of in vitro bioassays to detect the potential carcinogenicity of metal compounds is reviewed. The in vitro bioassays discussed include: bacterial reversion analysis to determine the capacity of metal salts to revert Salmonella typhimurium histidine auxotrophs or to revert Escherichia coli WP 2 tryp- to tr...

journal_title：Environmental health perspectives

authors： Sirover MA

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND:Prospective cohort studies constitute the major source of evidence about the mortality effects of chronic exposure to particulate air pollution. Additional studies are needed to provide evidence on the health effects of chronic exposure to particulate matter < or = 2.5 microm in aerodynamic diameter (PM(2.5)...

journal_title：Environmental health perspectives

authors： Zeger SL,Dominici F,McDermott A,Samet JM

更新日期：2008-12-01 00:00:00

abstract：:N-Substituted aromatic compounds can be metabolized in most species to N-acetylated derivatives that are themselves subject to further enzymatic transformations, including hydrolysis and N,O-acyltransfer. These proceses can either potentiate or ameliorate the biological responses to these N-substituted derivatives. De...

journal_title：Environmental health perspectives

authors： King CM,Glowinski IB

更新日期：1983-03-01 00:00:00

abstract：:Laboratory animal diets for studies to determine the endocrine-disrupting potential of chemicals are under scrutiny because they can affect both assay control values and assay sensitivity. Although phytoestrogen content is important, we have previously shown that a phytoestrogen-rich diet and a phytoestrogen-free diet...

journal_title：Environmental health perspectives

authors： Odum J,Tinwell H,Tobin G,Ashby J

更新日期：2004-11-01 00:00:00

abstract：:Carbon monoxide is widely distributed in the environment, and acute or chronic toxic effects may be of considerable public health significance. A review of the basis for current ambient standards is given. Mortality and morbidity studies have been negative or equivocal in relating carbon monoxide levels to health effe...

journal_title：Environmental health perspectives

authors： Kuller LH,Radford EP

更新日期：1983-10-01 00:00:00

abstract：:In this article we report a simple and efficient method for detecting nonsteroidal estrogens in a biologic sample. This method uses polyclonal antibodies to estradiol (E2) to immunoprecipitate these major biologically active steroidal estrogens, leaving behind the nonsteroidal estrogens, which are then detected in a c...

journal_title：Environmental health perspectives

authors： Natarajan K,Overstreet JW,Rogers JM,Denison MS,Chen J,Lohstroh PN,McConnell DS,Lasley BL

更新日期：2002-08-01 00:00:00

abstract：:Alveolar macrophages were treated with carbon blacks and adsorbates in order to evaluate the biologic effect of adsorbate, adsorbent and adsorbate-adsorbent complexes. Their capacity to phagocytize a subsequent challenge via the Fc-membrane receptor was quantified. Phagocytosis was suppressed in a dose-related manner ...

journal_title：Environmental health perspectives

authors： Jakab GJ,Risby TH,Sehnert SS,Hmieleski RR,Farrington JE

更新日期：1990-06-01 00:00:00

abstract：:Epidemiological studies examining the association between exposure to tap water contaminants (such as chlorination by-products) and disease outcomes (such as cancer and adverse reproductive outcomes) have been limited by inaccurate exposure assessment. Failure to take into account the variation in beverage and tap wat...

journal_title：Environmental health perspectives

authors： Shimokura GH,Savitz DA,Symanski E

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Studies suggest that phthalate exposures may adversely affect child respiratory health. OBJECTIVES:We evaluated associations between asthma diagnosed in children between 5 and 11 years of age and prenatal exposures to butylbenzyl phthalate (BBzP), di-n-butyl phthalate (DnBP), di(2-ethylhexyl) phthalate (DEH...

journal_title：Environmental health perspectives

authors： Whyatt RM,Perzanowski MS,Just AC,Rundle AG,Donohue KM,Calafat AM,Hoepner LA,Perera FP,Miller RL

更新日期：2014-10-01 00:00:00

abstract：:[This corrects the article DOI: 10.1289/EHP2580.]. ...

journal_title：Environmental health perspectives

authors： Sagiv SK,Harris MH,Gunier RB,Kogut KR,Harley KG,Deardorff J,Bradman A,Holland N,Eskenazi B

更新日期：2018-07-05 00:00:00

abstract：BACKGROUND:Rodent models for urban air pollution show consistent induction of inflammatory responses in major brain regions. However, the initial impact of air pollution particulate material on olfactory gateways has not been reported. OBJECTIVE:We evaluated the olfactory neuroepithelium (OE) and brain regional respon...

journal_title：Environmental health perspectives

authors： Cheng H,Saffari A,Sioutas C,Forman HJ,Morgan TE,Finch CE

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Methylmercury (MeHg) is a known neuro-toxicant. Emerging evidence indicates it may have adverse effects on the neuro-logic and other body systems at common low levels of exposure. Impacts of MeHg exposure could vary by individual susceptibility or be confounded by beneficial nutrients in fish containing MeHg...

journal_title：Environmental health perspectives

authors： Karagas MR,Choi AL,Oken E,Horvat M,Schoeny R,Kamai E,Cowell W,Grandjean P,Korrick S

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:There is a need to identify and evaluate an effective mitigation program for arsenic exposure from drinking water in Bangladesh. OBJECTIVE:We evaluated the effectiveness of a multifaceted mitigation program to reduce As exposure among 11,746 individuals in a prospective cohort study initiated in 2000 in Ara...

journal_title：Environmental health perspectives

authors： Chen Y,van Geen A,Graziano JH,Pfaff A,Madajewicz M,Parvez F,Hussain AZ,Slavkovich V,Islam T,Ahsan H

更新日期：2007-06-01 00:00:00

abstract：:Because of their history of widespread use in the United States and unknown long-term health effects, organophosphate pesticides (OPs) are being considered as a chemical class of interest in planning for the National Children's Study, a longitudinal study of children's environmental health. The availability and approp...

journal_title：Environmental health perspectives

authors： Wessels D,Barr DB,Mendola P

更新日期：2003-12-01 00:00:00

abstract：:This report reviews the recent literature on the adverse effects of occupational factors on fertility and related reproductive outcomes. Few studies fulfill the criteria of good study design because of small sample size, insensitive measures of effect, selection, recall, and observation bias, weak if any control of co...

journal_title：Environmental health perspectives

authors： Baranski B

更新日期：1993-07-01 00:00:00

abstract：:A comprehensive environmental fate and effects testing program, sponsored by the Chemical Manufacturers Association (CMA) Phthalate Esters Program Panel, has been completed. Based on the results, a preliminary safety assessment has shown that all of the 14 commercially important phthalates tested have sufficiently hig...

journal_title：Environmental health perspectives

authors： Group EF Jr

更新日期：1986-03-01 00:00:00

abstract：:Between 1966 and 1986, the childhood leukemia rate in Woburn, Massachusetts, was 4-fold higher than the national average. A multidisciplinary research team from MIT, which is being supported by the NIEHS Superfund Basic Research Program, has explored the possible importance of a temporal correlation between the period...

journal_title：Environmental health perspectives

authors： Durant JL,Chen J,Hemond HF,Thilly WG

更新日期：1995-09-01 00:00:00

abstract：:Studies on the fate of 14C-labeled vinyl chloride (VC) following oral administration and inhalation exposure in rats demonstrated that the disposition of VC in the body is a function of the dose. More importantly, from the data available, it appears that a correlation exists between doses of VC which cause tumors and ...

journal_title：Environmental health perspectives

authors： Watanabe PG,Gehring PJ

更新日期：1976-10-01 00:00:00

abstract：:Under a mandate from the U.S. Congress, the National Toxicology Program (NTP) of the U.S. Department of Health and Human Services conducts animal bioassays for carcinogenicity of potentially toxic chemicals to which the U.S. population might be exposed. Methyleugenol, a natural as well as synthesized substance, was no...

journal_title：Environmental health perspectives

authors： Schecter A,Lucier GW,Cunningham ML,Abdo KM,Blumenthal G,Silver AG,Melnick R,Portier C,Barr DB,Barr JR,Stanfill SB,Patterson DG Jr,Needham LL,Stopford W,Masten S,Mignogna J,Tung KC

更新日期：2004-05-01 00:00:00

abstract：:To evaluate the effectiveness of mass screening for uterine cancer in Japan, we compared the changes in the age-adjusted rates of potential years of life lost (PYLL) due to uterine cancer between 1969 and 1972 to 1973 through 1977 between the high coverage-rate (intensively screened) areas and the comparable control a...

journal_title：Environmental health perspectives

authors： Kuroishi T,Hirose K,Tominaga S

更新日期：1990-07-01 00:00:00

abstract：:We measured tumor-associated proteins (TAPs) and pollutants in blood, serum, and urine of 200 nonsmoking women 50-65 years of age, residing in the rural municipality of Peer or in Hoboken or Wilrijk, industrial suburbs of Antwerp, Belgium. Persons with occupational exposures or commuting to other towns were excluded. ...

journal_title：Environmental health perspectives

authors： van Larebeke NA,Bracke ME,Nelen V,Koppen G,Schoeters G,Van Loon H,Vlietinck R

更新日期：2006-06-01 00:00:00

abstract：:Asthma and lead poisoning are prevalent among urban children in the United States. Lead exposure may be associated with excessive production of immunoglobulin E, possibly increasing asthma risk and contributing to racial disparities. The objective of this study was to examine racial differences in the association of b...

journal_title：Environmental health perspectives

authors： Joseph CL,Havstad S,Ownby DR,Peterson EL,Maliarik M,McCabe MJ Jr,Barone C,Johnson CC

更新日期：2005-07-01 00:00:00

abstract：:Cytochrome P450 (CYP) enzymes catalyze the generation of reactive species capable of binding with cellular macromolecules, leading to acute and delayed toxicity. Since individual CYP forms differ markedly in their substrate preferences and regulation, the expression profiles of CYP in various cell types are important ...

journal_title：Environmental health perspectives

authors： Pelkonen O,Raunio H

更新日期：1997-06-01 00:00:00

abstract：:The available data on the influence of selenium on the toxicity of methylmercury and of methylmercury on selenium as a nutrient and toxic agent are reviewed. Selenium as selenite has a relative protective effect on acute and subacute toxicity of methylmercury in the rat and the quail. The protective mechanism is far f...

journal_title：Environmental health perspectives

authors： Skerfving S

更新日期：1978-08-01 00:00:00

abstract：:It has been estimated that 4 of 1,000 live births and 35% of spontaneous abortions are aneuploid and that an important proportion of embryo and newborn aneuploidy is of paternal origin. Exposure to organophosphorous pesticides (OP) has been associated with sperm hyperploidy/polyploidy. Therefore, we aimed to assess th...

journal_title：Environmental health perspectives

authors： Recio R,Robbins WA,Borja-Aburto V,Morán-Martínez J,Froines JR,Hernández RM,Cebrián ME

更新日期：2001-12-01 00:00:00