当前位置： SCI文献检索 > ENVIRONMENTAL HEALTH PERSPECTIVES期刊下所有文献 > Reduction in urinary arsenic levels in response to arsenic mitigation efforts in Araihazar, Bangladesh.

Reduction in urinary arsenic levels in response to arsenic mitigation efforts in Araihazar, Bangladesh.

Abstract：

BACKGROUND:There is a need to identify and evaluate an effective mitigation program for arsenic exposure from drinking water in Bangladesh. OBJECTIVE:We evaluated the effectiveness of a multifaceted mitigation program to reduce As exposure among 11,746 individuals in a prospective cohort study initiated in 2000 in Araihazar, Bangladesh, by interviewing participants and measuring changes in urinary As levels. METHODS:The interventions included a) person-to-person reporting of well test results and health education; b) well labeling and village-level health education; and c) installations of 50 deep, low-As community wells in villages with the highest As exposure. RESULTS:Two years after these interventions, 58% of the 6,512 participants with unsafe wells (As >/=50 microg) at baseline had responded by switching to other wells. Well labeling and village-level health education was positively related to switching to safe wells (As < 50 mug/L) among participants with unsafe wells [rate ratio (RR) = 1.84; 95% confidence interval (CI), 1.60-2.11] and inversely related to any well switching among those with safe wells (RR = 0.80; 95% CI, 0.66-0.98). The urinary As level in participants who switched to a well identified as safe (< 50 microg As/L) dropped from an average of 375 microg As/g creatinine to 200 microg As/g creatinine, a 46% reduction toward the average urinary As content of 136 microg As/g creatinine for participants that used safe wells throughout. Urinary As reduction was positively related to educational attainment, body mass index, never-smoking, absence of skin lesions, and time since switching (p for trend < 0.05). CONCLUSIONS:Our study shows that testing of wells and informing households of the consequences of As exposure, combined with installation of deep community wells where most needed, can effectively address the continuing public health emergency from arsenic in drinking water in Bangladesh.

journal_name

Environ Health Perspect

journal_title

Environmental health perspectives

authors

Chen Y,van Geen A,Graziano JH,Pfaff A,Madajewicz M,Parvez F,Hussain AZ,Slavkovich V,Islam T,Ahsan H

doi

10.1289/ehp.9833

subject

Has Abstract

pub_date

2007-06-01 00:00:00

pages

917-23

issue

eissn

0091-6765

issn

1552-9924

journal_volume

115

pub_type

杂志文章

在线工具

Reduction in urinary arsenic levels in response to arsenic mitigation efforts in Araihazar, Bangladesh.