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Too sweet for autophagy: hexokinase inhibition of mTORC1 activates autophagy.

Abstract：

:In this issue, Roberts et al. (2014) describe how hexokinase and mTORC1 cooperate to sense disequilibrium between glucose uptake and utilization and direct the balance of anabolism and catabolism to ensure the appropriate use of cellular resources.

journal_name

Mol Cell

journal_title

Molecular cell

authors

Kundu M

doi

10.1016/j.molcel.2014.02.009

subject

Has Abstract

pub_date

2014-02-20 00:00:00

pages

517-8

issue

4

eissn

1097-2765

issn

1097-4164

pii

S1097-2765(14)00124-5

journal_volume

53

pub_type

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