Abstract：
:High plasticity to utilize different nutrients to adapt metabolic stress is one of the hallmarks for cancer cells. However, the underlying mechanisms by which cancer cells reprogram metabolic machinery in response to metabolic stress remain largely unclear. In this issue of Molecular Cell, Wang et al. (2019) report that glutamate dehydrogenase 1 (GDH1) induces an unconventional regulation of the NF-κB pathway under glucose deprivation, thereby stimulating glycolysis in glioblastomas.
journal_name
Mol Celljournal_title
Molecular cellauthors
Di Conza G,Tsai CH,Ho PCdoi
10.1016/j.molcel.2019.09.002subject
Has Abstractpub_date
2019-10-03 00:00:00pages
1-3issue
1eissn
1097-2765issn
1097-4164pii
S1097-2765(19)30687-2journal_volume
76pub_type
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