[Dietary supplements as a treatment for cervical cancer: a systematic review].

Abstract:

INTRODUCTION:Cervical cancer and cervical intraepithelial neoplasia (CIN) require a careful selection of conventional and complementary therapies. The inclusion of dietary supplements within the aforementioned treatments set the tone within treatments. However, there are no reports of what kind of supplements could be used to provide a better response to the disease in these patients. OBJECTIVE:In this review, we analyze clinical trials of the past 20 years that evaluated dietary supplements on this population, with the objective to raise awareness on which of them are viable to be administered. METHODS:We performed a search for clinical trials that used a dietary supplement in women with cervical cancer and some degree of NIC analyzing them how to use the supplement, the conventional treatment, deficiency of the nutrient or compound to be evaluated, the characteristics of the population, the clinical trial and the supplement, as well as dosage and their effects. RESULTS:Twenty were in total the number of studies reviewed. The articles were classified according to the nature of the supplement: Retinoids, vitamin E, probiotics, indoles, multivitamin, folic acid and selenium. CONCLUSION:Some supplements were found to be effective in the treatment of cervical cancer and CIN. However, their effect depends on specific factors of the disease. The correct management of dietary supplements is an effective aid to help the patient with cancer and therefore, it is important to define what complementary therapies can be used for this population. :Introducción: En el cáncer cervicouterino (CaCu) y neoplasias intraepiteliales cervicales (NIC) se requiere de una cuidadosa selección de terapias convencionales y complementarias, la inclusión de suplementos dietéticos dentro de ellas marcaría la pauta dentro de los tratamientos. Sin embargo, no se tiene algún reporte de qué tipo de suplementos pudieran ser utilizados para brindar una mejor respuesta ante la enfermedad por estas pacientes. Objetivo: En la presente revisión se analizan los ensayos clínicos de los últimos 20 años que evaluaron suplementos dietéticos en esta población, con el objetivo de dar a conocer cuáles de ellos son viables para ser administrados. Metodología: Se realizó una búsqueda de ensayos clínicos que utilizaron algún suplemento dietario en mujeres con CaCu y algún grado de NIC analizando en ellos el modo de utilización del suplemento; el tratamiento convencional; si existe una deficiencia del nutriente ó compuesto a evaluar; las características de la población, del ensayo clínico y del suplemento; así como la dosis y los efectos esperados. Resultados: Veinte fueron en total el número de estudios analizados. Los artículos fueron clasificados según la naturaleza del suplemento: Retinoides, vitamina E, probióticos, indoles, multivitamínico, ácido fólico y selenio. Conclusión: Para el tratamiento de CaCu y NIC resultaron efectivos algunos de los suplementos encontrados en esta revisión, sin embargo su efecto dependerá de diferentes factores propios de la enfermedad. Debido a esto, es necesario el manejo correcto de los suplementos dietéticos para poder ser utilizados eficientemente como tratamiento complementario en esta población.

journal_name

Nutr Hosp

journal_title

Nutricion hospitalaria

authors

Arellano Ortiz AL,Jiménez Vega F,Salcedo Vargas M

doi

10.3305/nutr hosp.v28in06.6816

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

1770-80

issue

6

eissn

0212-1611

issn

1699-5198

journal_volume

28

pub_type

杂志文章,评审
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    authors: Jáuregui Lobera I,Bolaños P,Carbonero R,Valero Blanco E

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  • Macronutrients and micronutrients in Spanish adult vegans (Mediterranean population).

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    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.02939

    authors: García-Morant A,Cortés-Castell E,Palazón-Bru A,Martínez-Amorós N,Gil-Guillén VF,Rizo-Baeza M

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    pub_type: 杂志文章

    doi:10.3305/nh.2013.28.1.6185

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    doi:10.3305/nh.2014.29.5.7421

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  • [Use of enteral nutrition products in a general hospital].

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    journal_title:Nutricion hospitalaria

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    doi:

    authors: Marín Pozo JF,Nacle López I,Zambora Ardoy MA,Vílchez Medina T,Millán García R,Mora Mora MA

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    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章,meta分析,评审

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    authors: Castillo-Lancellotti C,Tur Marí JA,Uauy Dagach R

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    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Criado MT,De Juana P,Hillman N,Koning A,Del Olmo D,Vázquez C,García-Alvarez A

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    pub_type: 杂志文章

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    authors: Díaz Romero C,Henríquez Sánchec P,López Blanco F,Rodríguez Rodríguez E,Serra Majem L

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    authors: Barrios Ospino Y,Díaz N,Meertens L,Naddaf G,Solano L,Fernández M,Flores A,González M

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    journal_title:Nutricion hospitalaria

    pub_type: 指南,杂志文章,评审

    doi:10.1590/S0212-16112011000800011

    authors: Planas M,Fernández-Ortega JF,Abilés J,Metabolism and Nutrition Working Group of the Spanish Society of Intensive Care Medicine and Coronary units.

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    authors: Vaquero L,Alvarez-Cuenllas B,Rodríguez-Martín L,Aparicio M,Jorquera F,Olcoz JL,Vivas S

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  • Interaction between mercury (Hg), arsenic (As) and selenium (Se) affects the activity of glutathione S-transferase in breast milk; possible relationship with fish and sellfish intake.

    abstract::Breast milk is regarded as an ideal source of nutrients for the growth and development of neonates, but it can also be a potential source of pollutants. Mothers can be exposed to different contaminants as a result of their lifestyle and environmental pollution. Mercury (Hg) and arsenic (As) could adversely affect the ...

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    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

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    authors: Mardones F,Arnaiz P,Barja S,Giadach C,Villarroel L,Domínguez A,Castillo O,Farias M

    更新日期:2013-11-01 00:00:00

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    pub_type: 杂志文章

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    pub_type: 杂志文章

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    pub_type: 临床试验,杂志文章,随机对照试验

    doi:

    authors: Pastó L,Pellicer E,Llopart R,Gómez JA,Cardona D

    更新日期:1991-01-01 00:00:00

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    journal_title:Nutricion hospitalaria

    pub_type: 临床试验,杂志文章,多中心研究

    doi:

    authors: Grau T,Bonet A,Grupo de Trabajo de Metabolismo y Nutrición de la Sociedad Española de.,Medicina Intensiva Critica y Unidades Coronarias.

    更新日期:2005-07-01 00:00:00

  • [Dietetic-nutritional treatment in chronic radiation enteritis. A complex clinical case].

    abstract::We present a clinical case of chronic radiation enteritis, with follow-up over 34 months, the main features of which were as follows: A 60-year-old female patient with adenocarcinoma of the rectum who required a left hemicolectomy (Hartmann), receiving chemotherapy with fluorouracil and external radiation therapy (45 ...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Fernández de Bustos A,Pita Mercé AM

    更新日期:2003-07-01 00:00:00

  • [Nutrition and behavioral eating disorders: anorexia and bulimia nervosa].

    abstract::Behavioral eating disorders (BED's) have shown an intense growth in the last years. They are considered to be caused by multiple factors, showing a bio-psycho-socio-cultural etiology. Although there are clinical signs that could alert the physician and allow an early diagnosis, their final diagnosis must meet certain ...

    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:

    authors: Miján de la Torre A,Velasco Vallejo JL

    更新日期:1999-05-01 00:00:00

  • [Survey on hypoglycaemia diagnosis and glucometer use-which is the most widely used glucometer in Spanish neonatology units?]

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    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章

    doi:10.20960/nh.03203

    authors: Martín Ruiz N,Rite Gracia S,García Íñiguez JP,Samper Villagrasa MP

    更新日期:2020-10-21 00:00:00

  • Somatotype tendency in Chilean adolescents from Valparaíso: review from 1979 to 2011.

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    journal_title:Nutricion hospitalaria

    pub_type: 杂志文章,评审

    doi:10.3305/nh.2015.31.3.8425

    authors: Lizana PA,Olivares R,Berral FJ

    更新日期:2014-12-17 00:00:00