Sequence specificity of tetrahydrobenzopsoralen photobinding to DNA.

abstract：:Detergent solubilized bacteriorhodopsin (BR) proteins which contain alterations made by site-directed mutagenesis (Asp-96----Asn, D96N; Asp-85----Asn, D85N; and Arg-82----Gln, R82Q) have been studied with resonance Raman spectroscopy. Raman spectra of the light-adapted (BRLA) and M species in D96N are identical to tho...

journal_title：Photochemistry and photobiology

authors： Lin SW,Fodor SP,Miercke LJ,Shand RF,Betlach MC,Stroud RM,Mathies RA

更新日期：1991-03-01 00:00:00

abstract：:Solid-state NMR spectroscopy gives a powerful avenue for investigating G protein-coupled receptors and other integral membrane proteins in a native-like environment. This article reviews the use of solid-state (2)H NMR to study the retinal cofactor of rhodopsin in the dark state as well as the meta I and meta II photo...

journal_title：Photochemistry and photobiology

authors： Brown MF,Martínez-Mayorga K,Nakanishi K,Salgado GF,Struts AV

更新日期：2009-03-01 00:00:00

abstract：:UV light leads to release of different secretory factors from irradiated cells of which some of them have been characterized. We have reported earlier that cells exposed to the supernatant medium from irradiated cells were resistant to killing by some genotoxic agents. In this study, we present our finding that demons...

journal_title：Photochemistry and photobiology

authors： Ghosh R,Guha D,Bhowmik S

更新日期：2012-05-01 00:00:00

abstract：:The thermodynamic parameters for the formation of the free radicals upon electron transfer quenching of the flavin triplet state (3FMN) by tryptophan and tyrosine, Delta(FR)H and Delta(FR)V, were obtained in aqueous solution by the application of laser-induced optoacoustic spectroscopy at various temperatures. The Del...

journal_title：Photochemistry and photobiology

authors： Crovetto L,Martínez-Junza V,Braslavsky SE

更新日期：2006-01-01 00:00:00

abstract：:Activation of expression of the heme oxygenase (HO) gene appears to be involved in a cellular defense system in mammalian cells. We now demonstrate that while HO-1 mRNA levels are strongly inducible in dermal fibroblasts they are barely inducible in human epidermal keratinocytes following oxidative stress (UVA radiati...

journal_title：Photochemistry and photobiology

authors： Applegate LA,Noël A,Vile G,Frenk E,Tyrrell RM

更新日期：1995-03-01 00:00:00

abstract：:The photophysical properties of Piroxicam, a nonsteroidal anti-inflammatory drug (NSAID), were investigated at different pHext values in reversed micelles of Aerosol-OT (AOT) in iso-octane, using both steady-state and picosecond time-resolved fluorescence spectroscopy. In contrast with the very complex data obtained i...

journal_title：Photochemistry and photobiology

authors： Andrade SM,Costa SM,Pansu R

更新日期：2000-04-01 00:00:00

abstract：:An open three-compartment pharmacokinetic model was applied to the in vivo quantitative structure-activity relationship (QSAR) data of a homologous series of pyropheophorbide photosensitizers for photodynamic therapy (PDT). The physical model was a lipid compartment sandwiched between two identical aqueous compartment...

journal_title：Photochemistry and photobiology

authors： Potter WR,Henderson BW,Bellnier DA,Pandey RK,Vaughan LA,Weishaupt KR,Dougherty TJ

更新日期：1999-11-01 00:00:00

abstract：:The UVA and UVB components of sunlight can produce three classes of bipyrimidine DNA photolesions [cyclobutane pyrimidine dimers (CPDs), pyrimidine (6-4) pyrimidone photoproducts (6-4PPs) and related Dewar valence isomers (DewarPPs)]. The UVA/UVB ratio of sunlight is high in winter and low in summer in the Northern He...

journal_title：Photochemistry and photobiology

authors： Nishimura K,Ikehata H,Douki T,Cadet J,Sugiura S,Mori T

更新日期：2020-12-03 00:00:00

abstract：:Schinus terebinthifolius is a plant rich in phenolic compounds, which have antioxidant properties and can provide new opportunities for treatment and prevention of diseases mediated by ultraviolet radiation like photoaging and skin cancer. The aim of this study was to evaluate the photoprotective potential and ex vivo...

journal_title：Photochemistry and photobiology

authors： Bulla MK,Hernandes L,Baesso ML,Nogueira AC,Bento AC,Bortoluzzi BB,Serra LZ,Cortez DA

更新日期：2015-05-01 00:00:00

abstract：:The fluorescent pH probe carboxy-seminaphtorhodafluor-1 (C-Snarf-1) has been used for laser microspectro-fluorometric assays of intracellular pH in 3T3 mouse fibroblasts treated with hypocrellin A. These results are compared to those previously obtained with the structurally related hydroxylated polycyclic quinone, hy...

journal_title：Photochemistry and photobiology

authors： Chaloupka R,Sureau F,Kocisova E,Petrich JW

更新日期：1998-07-01 00:00:00

abstract：:The transport mechanisms of 5-aminolevulinic acid methyl ester (5-ALA-ME) have been studied in a human adenocarcinoma cell line (WiDr) by means of 14[C]-labeled 5-ALA-ME. The transport was found to be partly Na+ dependent, while the extracellular Cl- concentration did not affect the uptake. The transport of 5-ALA-ME i...

journal_title：Photochemistry and photobiology

authors： Gederaas OA,Holroyd A,Brown SB,Vernon D,Moan J,Berg K

更新日期：2001-02-01 00:00:00

abstract：:Under physiological conditions B-form DNA is an exceedingly stable structure. However, experimental evidences obtained through nuclear magnetic resonance and fluorescence anisotropy suggest that the structure of the double helix fluctuates substantially. We describe photoacoustic phase modulation frequency measurement...

journal_title：Photochemistry and photobiology

authors： Bugs MR,Cornélio ML

更新日期：2001-10-01 00:00:00

abstract：:The total ozone column (TOC) is the most significant quantity for estimating the erythemally effective UV radiation under clear sky conditions. Uncertainties in TOC measurements and a limited spatial and temporal resolution therefore influence the quality of calculated erythemally effective radiation. The UV Index, th...

journal_title：Photochemistry and photobiology

authors： Schmalwieser AW,Erbertseder T,Schauberger G,Weihs P

更新日期：2008-09-01 00:00:00

abstract：:Chlorprothixene (CPTX, Taractan) is a low potency antipsychotic mainly used for the treatment of psychotic disorders (e.g. schizophrenia) and acute mania occurring as part of bipolar disorders. As in the case of other numerous drugs used in the treatment of psychiatric disorders, CPTX presents geometric isomerism. The...

journal_title：Photochemistry and photobiology

authors： Piñero LE,García C,Lhiaubet-Vallet V,Oyola R,Miranda MA

更新日期：2009-07-01 00:00:00

abstract：:In this paper, we propose a new physical method in combination with mixed solution of thiazone and polyethylene glycol 400 (thiazone PEG 400 solution) penetration into tissue to assess the skin optical clearing. Four treatments were performed: (1) control group (C); (2) polyethylene glycol 400 (PEG400); (3) 0.25% thia...

journal_title：Photochemistry and photobiology

authors： Zhong H,Guo Z,Wei H,Guo L,Wang C,He Y,Xiong H,Liu S

更新日期：2010-05-01 00:00:00

abstract：:The contribution of DNA strand breaks accumulating in the course of nucleotide excision repair to upregulation of the p53 tumor suppressor protein was investigated in human dermal fibroblast strains after treatment with 254 nm ultraviolet (UV) light. For this purpose, fibroblast cultures were exposed to UV and incubat...

journal_title：Photochemistry and photobiology

authors： Enns L,Murray D,Mirzayans R

更新日期：2000-10-01 00:00:00

abstract：:On direct photoexcitation, subpicosecond time-resolved absorption spectroscopy revealed that the 1B(u)-type singlet excited state of all-trans-lycopene in chloroform was about seven times more efficient than all-trans-beta-carotene in generating the radical cation. The time constant of radical cation generation from t...

journal_title：Photochemistry and photobiology

authors： Han RM,Wu YS,Feng J,Ai XC,Zhang JP,Skibsted LH

更新日期：2004-09-01 00:00:00

abstract：:UV radiation is a potent DNA damaging agent and a known inducer of skin cancer in experimental animals. There is excellent scientific evidence to indicate that most non-melanoma human skin cancers are induced by repeated exposure to sunlight. UV radiation is unique in that it induces DNA damage that differs from the l...

journal_title：Photochemistry and photobiology

authors： Ananthaswamy HN,Pierceall WE

更新日期：1990-12-01 00:00:00

abstract：:The temperature dependence of the uptake phase of 5-aminolevulinic acid (ALA) and the following production phase of protoporphyrin IX (PpIX) in normal mouse skin was investigated. A cream containing 20% ALA was topically applied on the skin for 10 min. The amount of ALA-induced PpIX was evaluated by measuring the fluo...

journal_title：Photochemistry and photobiology

authors： Juzenas P,Sørensen R,Iani V,Moan J

更新日期：1999-04-01 00:00:00

abstract：:Ultraviolet radiation (UVR) is hazardous to patients with photosensitive skin disorders, such as lupus erythematosus, xeroderma pigmentosum and skin cancer. As such, these patients are advised to minimize their exposure to UVR. Classically, this is accomplished through careful avoidance of sun exposure and artificial ...

journal_title：Photochemistry and photobiology

authors： Klein RS,Werth VP,Dowdy JC,Sayre RM

更新日期：2009-07-01 00:00:00

abstract：:Direct irradiation of estrone aryl and methyl sulfonates in different organic solvents under nitrogen atmosphere was investigated under steady-state conditions. The estrone derivatives reacted efficiently through the photo-Fries rearrangement reaction involving [1;3]-sulfonyl migration providing the ortho-sulfonyl est...

journal_title：Photochemistry and photobiology

authors： Quindt MI,Gola GF,Ramirez JA,Bonesi SM

更新日期：2021-01-01 00:00:00

abstract：:To determine the impact of delivery vehicles in photosensitizing efficacy of HPPH, a hydrophobic photosensitizer was dissolved in various formulations: 1% Tween 80/5% dextrose, Pluronic P-123 and Pluronic F-127 in 0.5%, 1% and 2% phosphate buffer solutions (PBS). HPPH was also conjugated to Pluronic F-127, and the res...

journal_title：Photochemistry and photobiology

authors： Cacaccio J,Durrani F,Cheruku RR,Borah B,Ethirajan M,Tabaczynski W,Pera P,Missert JR,Pandey RK

更新日期：2020-05-01 00:00:00

abstract：:We previously reported that a low level of lysosomal photodamage potentiated the phototoxic effect of subsequent mitochondrial photodamage mediated by the benzoporphyrin derivative (BPD) in murine hepatoma 1c1c7 cells. This was attributed to release of Ca2+ from damaged lysosomes and a calpain-mediated conversion of t...

journal_title：Photochemistry and photobiology

authors： Kessel D,Reiners JJ Jr

更新日期：2017-11-01 00:00:00

abstract：:Polysulphone (PS) dosimetry has been a widely used technique for more than 30 years to quantify the erythemally effective UV dose received by anatomic sites (personal exposure). The calibration of PS dosimeters is an important issue as their spectral response is different from the erythemal action spectrum. It is perf...

journal_title：Photochemistry and photobiology

authors： Casale GR,Siani AM,Diémoz H,Kimlin MG,Colosimo A

更新日期：2012-01-01 00:00:00

abstract：:The relationship between levels of in vivo accumulated photosensitizer (Photofrin II), photodynamic cell inactivation upon in vitro or in vivo illumination, and changing tumor oxygenation was studied in the radiation-induced fibrosarcoma (RIF) mouse tumor model. In vivo porphyrin uptake by tumor cells was assessed by ...

journal_title：Photochemistry and photobiology

authors： Henderson BW,Fingar VH

更新日期：1989-03-01 00:00:00

abstract：:We studied the spectral characteristics of the larvae of three sympatric Belgian species of fireflies, Lampyris noctiluca, Phosphaenus hemipterus and Lamprohiza splendidula. An in vivo spectral study was performed to compare bioluminescence spectra. The emission spectrum of a laboratory reared female L. noctiluca was ...

journal_title：Photochemistry and photobiology

authors： De Cock R

更新日期：2004-04-01 00:00:00

abstract：:The mechanism of caspase-3-dependent apoptosis induced by photodynamic therapy (PDT) of cultured Chinese hamster V79 cells with pheophorbide a (PPa) was investigated. The PPa-PDT induced rapid apoptosis within 30 min after irradiation of cells. This apoptosis was inhibited by the 1O2 quencher N3- and caspase-3 inhibit...

journal_title：Photochemistry and photobiology

authors： Inanami O,Yoshito A,Takahashi K,Hiraoka W,Kuwabara M

更新日期：1999-10-01 00:00:00

abstract：:It has previously been demonstrated that chronic low-dose solar-simulated UV radiation could induce both local and systemic immunosuppression as well as tolerance to a topically applied hapten. In this study, we have used a chronic low-dose UV-irradiation protocol to investigate the effects of UVA on the skin immune s...

journal_title：Photochemistry and photobiology

authors： Bestak R,Halliday GM

更新日期：1996-12-01 00:00:00

abstract：:We have compared the distributions of two stable UV photoproducts in nucleosome core DNA at the single-nucleotide level using a T4 polymerase-exonuclease mapping procedure. The distribution of pyrimidine-pyrimidone (6-4) dimers was uncovered by reversing the major UV photo-product, cis-syn cyclobutane pyrimidine dimer...

journal_title：Photochemistry and photobiology

authors： Gale JM,Smerdon MJ

更新日期：1990-04-01 00:00:00

abstract：:Collagen was exposed to an ultraviolet (UV) lamp that emitted predominantly in the UVB range. The cross-linking of collagen type I and type IV by UV irradiation was observed. Amino acid analyses revealed that Tyr residues in both collagen types I and IV were decreased by irradiation. In collagen type IV, losses of His...

journal_title：Photochemistry and photobiology

authors： Kato Y,Nishikawa T,Kawakishi S

更新日期：1995-04-01 00:00:00