Disseminated aspergillosis in a patient with cystic fibrosis and allergic bronchopulmonary aspergillosis.

Abstract:

:Allergic bronchopulmonary aspergillosis (ABPA) is a well-known complication of cystic fibrosis (CF), with an estimated incidence of up to 11%. In patients with CF, the diagnosis of ABPA must be based on significant elevation of Aspergillus fumigatus (Af) antibody and total serum IgE, since it is common to already have other clinical and laboratory features of ABPA (Laufer et al., J Allergy Clin Immunol. 1984; 73:44-48). Once ABPA is identified in a patient, institution of corticosteroids is standard therapy. Invasive aspergillosis is a rare occurrence in patients with CF with or without ABPA, and has been reported in only one young adult who did not have ABPA (Giudotti et al., Am J Med Sci. 1982; 283:157-160). We present a case of a 15-year-old male with CF and ABPA who developed disseminated aspergillosis.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Chung Y,Kraut JR,Stone AM,Valaitis J

doi

10.1002/ppul.1950170210

subject

Has Abstract

pub_date

1994-02-01 00:00:00

pages

131-4

issue

2

eissn

8755-6863

issn

1099-0496

journal_volume

17

pub_type

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