Looking beyond patients: Can parents' quality of life predict asthma control in children?

Abstract:

BACKGROUND:Social and family factors may influence the probability of achieving asthma control in children. Parents' quality of life has been insufficiently explored as a predictive factor linked to the probability of achieving disease control in asthmatic children. OBJECTIVE:Determine whether the parents' quality of life predicts medium-term asthma control in children. METHODS:Longitudinal study of children between 4 and 14 years of age, with active asthma. The parents' quality of life was evaluated using the specific IFABI-R instrument, in which scores were higher for poorer quality of life. Its association with asthma control measures in the child 16 weeks later was analyzed using multivariate methods, adjusting the effect for disease, child and family factors. RESULTS:The data from 452 children were analyzed (median age 9.6 years, 63.3% males). The parents' quality of life was predictive for asthma control; each point increase on the initial IFABI-R score was associated with an adjusted odds ratio (95% confidence interval) of 0.56 (0.37-0.86) for good control of asthma on the second visit, 2.58 (1.62-4.12) for asthma exacerbation, 2.12 (1.33-3.38) for an unscheduled visit to the doctor, and 2.46 (1.18-5.13) for going to the emergency room. The highest quartile for the IFABI-R score had a sensitivity of 34.5% and a specificity of 82.2% to predict poorly controlled asthma. CONCLUSIONS:Parents' poorer quality of life is related to poor, medium-term asthma control in children. Assessing the parents' quality of life could aid disease management decisions. Pediatr Pulmonol. 2016;51:670-677. © 2015 Wiley Periodicals, Inc.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Cano-Garcinuño A,Mora-Gandarillas I,Bercedo-Sanz A,Callén-Blecua MT,Castillo-Laita JA,Casares-Alonso I,Forns-Serrallonga D,Tauler-Toro E,Alonso-Bernardo LM,García-Merino Á,Moneo-Hernández I,Cortés-Rico O,Carvajal-Urueña I,Morel

doi

10.1002/ppul.23336

subject

Has Abstract

pub_date

2016-07-01 00:00:00

pages

670-7

issue

7

eissn

8755-6863

issn

1099-0496

journal_volume

51

pub_type

杂志文章
  • Serum eosinophil cationic protein as a predictor of wheezing after bronchiolitis.

    abstract::We have evaluated the role of eosinophil cationic protein (ECP) concentrations in serum in predicting wheezing after bronchiolitis, during infancy and early childhood. A prospective study at a university hospital serving all pediatric patients in a defined area was designed. Serum ECP concentrations were measured in 9...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/(sici)1099-0496(199706)23:6<397::aid-ppul1

    authors: Reijonen TM,Korppi M,Kuikka L,Savolainen K,Kleemola M,Mononen I,Remes K

    更新日期:1997-06-01 00:00:00

  • Glucocorticoids and lung development in the fetus and preterm infant.

    abstract::During the final prenatal period of fetal lung development in humans, important maturational processes occur, including the production of surfactant necessary to decrease surface tension at the air-liquid interface of the alveoli. During early gestation, the glucocorticoid receptor is expressed in the fetal lung, and ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,评审

    doi:10.1002/ppul.1092

    authors: Bolt RJ,van Weissenbruch MM,Lafeber HN,Delemarre-van de Waal HA

    更新日期:2001-07-01 00:00:00

  • Mechanically ventilated premature babies have sex differences in specific elastance: A pilot study.

    abstract:OBJECTIVES:A pilot study to compare pulmonary mechanics in a neonatal intensive care unit (NICU) cohort, specifically, comparing lung elastance between male and female infants in the NICU. HYPOTHESIS:Anecdotally, male infants are harder to ventilate than females. We hypothesize that males have higher model-based elast...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24538

    authors: Kim KT,Knopp J,Dixon B,Chase JG

    更新日期:2020-01-01 00:00:00

  • Time to publication as full reports of abstracts of randomized controlled trials in cystic fibrosis.

    abstract:OBJECTIVES:To determine 1) what proportion of abstracts of randomized controlled trials (RCTs) presented at international conferences on cystic fibrosis (CF) are published as full reports, 2) time to publication, and 3) factors that might delay or prevent publication. METHODS:At the end of 1995, the Cochrane CF Group'...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-0496(199808)26:2<101::aid-ppul5

    authors: Cheng K,Preston C,Ashby D,O'Hea U,Smyth RL

    更新日期:1998-08-01 00:00:00

  • Infrared end-tidal CO2 measurement does not accurately predict arterial CO2 values or end-tidal to arterial PCO2 gradients in rabbits with lung injury.

    abstract::End-tidal PCO2 (PETCO2) measurements from two commercially available neonatal infrared capnometers with different sampling systems and a mass spectrometer were compared with arterial PCO2 (PaCO2) to determine whether the former could predict the latter in mechanically ventilated rabbits with and without lung injury. T...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950170309

    authors: Hopper AO,Nystrom GA,Deming DD,Brown WR,Peabody JL

    更新日期:1994-03-01 00:00:00

  • Bronchial provocation testing with dry powder mannitol in children with cystic fibrosis.

    abstract:BACKGROUND/AIM:There has been recent interest in dry powder inhaled mannitol as a therapeutic agent in patients with cystic fibrosis (CF). It is has been shown to increase mucociliary clearance (MCC) by rehydrating the airway. To date there have been no studies exclusively in children with CF examining the effect of dr...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20903

    authors: Minasian C,Wallis C,Metcalfe C,Bush A

    更新日期:2008-11-01 00:00:00

  • Evaluation and management of pulmonary disease in ataxia-telangiectasia.

    abstract:SUMMARY:Ataxia-telangiectasia (A-T) is a rare autosomal recessive disorder caused by mutations in the ATM gene, resulting in faulty repair of breakages in double-stranded DNA. The clinical phenotype is complex and is characterized by neurologic abnormalities, immunodeficiencies, susceptibility to malignancies, recurren...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21277

    authors: McGrath-Morrow SA,Gower WA,Rothblum-Oviatt C,Brody AS,Langston C,Fan LL,Lefton-Greif MA,Crawford TO,Troche M,Sandlund JT,Auwaerter PG,Easley B,Loughlin GM,Carroll JL,Lederman HM

    更新日期:2010-09-01 00:00:00

  • Assessing bronchodilator responsiveness in infants using partial expiratory flow-volume curves.

    abstract::Our objective was to compare the effectiveness of maximum forced expiratory flow measured at functional residual capacity (V'maxFRC) and the ratio of flow at 75% of the forced expiratory volume to peak forced expiratory flow (FEF(75)/FEF(peak)) for detecting bronchodilator-related changes in wheezy infants. In 55 infa...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章

    doi:10.1002/ppul.10325

    authors: Sheikh S,Castile R,Hayes J,McCoy K,Eid N

    更新日期:2003-09-01 00:00:00

  • A novel combined treatment for plasminogen deficiency with lung involvement.

    abstract::Plasminogen deficiency is characterized by fibrin-rich pseudomembrane formation on all mucosal surfaces, particularly the conjunctiva. Respiratory system involvement is common; fibrin often obstructs the upper or lower respiratory tract, causing death. Although many treatments have been applied, no definitive treatmen...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24563

    authors: Kilinc AA,Tarcin G,Kurugoglu S,Schuster V,Cokugras H,Celkan T

    更新日期:2020-01-01 00:00:00

  • sTREM-1 is elevated in cystic fibrosis and correlates with proteases.

    abstract:BACKGROUND:sTREM-1 (soluble triggering receptor expressed on myeloid cells-1) is a novel inflammatory marker that may be of clinical use in cystic fibrosis (CF). Dysregulation of the TREM pathway has been demonstrated in other inflammatory diseases and modulation in animal models has therapeutic benefit. We hypothesise...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23650

    authors: Forrester DL,Barr HL,Fogarty A,Knox A

    更新日期:2017-04-01 00:00:00

  • Harvesting airway surface liquid: a comparison of two techniques.

    abstract::The quantity and composition of airway surface liquid (ASL) are essential to host defense. To date, attempts to harvest ASL and measure its composition have yielded conflicting results. We investigated the physical principles underlying two techniques that were proposed for harvesting ASL: filter paper pledgets and po...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.10409

    authors: Landry JS,Landry C,Cowley EA,Govindaraju K,Eidelman DH

    更新日期:2004-02-01 00:00:00

  • Validation of novel wheeze phenotypes using longitudinal airway function and atopic sensitization data in the first 6 years of life: evidence from the Southampton Women's survey.

    abstract:BACKGROUND:In 1995 the Tucson Children's Respiratory Study (TCRS) identified clinically distinct phenotypes amongst early wheezers; the Avon Longitudinal Study of Parents And Children (ALSPAC) has recently re-examined these. OBJECTIVES:To validate statistically derived ALSPAC phenotypes in the Southampton Women's Surv...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22766

    authors: Collins SA,Pike KC,Inskip HM,Godfrey KM,Roberts G,Holloway JW,Lucas JS,Southampton Women's Survey Study Group.

    更新日期:2013-07-01 00:00:00

  • Pulmonary dysfunction after primary closure of an abdominal wall defect and its improvement with bronchodilators.

    abstract::To determine the extent of pulmonary dysfunction following primary closure of an abdominal wall defect, we obtained pulmonary function tests (PFT) in 11 newborn infants with gastroschisis and 6 with large omphaloceles admitted to a newborn ICU in a children's hospital. Patients were 1 to 30 days of age at the time of ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950120309

    authors: Nakayama DK,Mutich R,Motoyama EK

    更新日期:1992-03-01 00:00:00

  • Serum soluble receptor for advanced glycation end-products during acute bronchiolitis in infant: Prospective study in 93 cases.

    abstract:INTRODUCTION:Acute bronchiolitis is a major cause of acute respiratory distress in infants. The soluble receptor for advanced glycation end-products (sRAGE) is a biomarker of pulmonary damage processes, with a diagnostic and a prognostic value in acute respiratory distress syndrome (ARDS). The RAGE pathway is also impl...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24141

    authors: Egron C,Roszyk L,Rochette E,Jabaudon M,Sapin V,Mulliez A,Labbé A,Coste K

    更新日期:2018-10-01 00:00:00

  • Partitioning the respiratory effects of airway citric acid and normal saline in lambs.

    abstract::Aspiration is common in the intubated human neonate. Thus, the ventilatory and blood gas responses to citric acid and saline instillation into different airway sites were studied in ten awake, unanesthetised lambs, breathing spontaneously via a tracheostomy tube. With a system of balloons, 1 ml of saline or citric aci...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950030112

    authors: Hutchison AA,Caton D,Thomas RG,Bucciarelli RL

    更新日期:1987-01-01 00:00:00

  • Partitioning of alterations in pulmonary mechanics due to vascular engorgement in piglets.

    abstract::The aim of our study was to determine the effects of pulmonary vascular engorgement on airways and pulmonary tissues in juvenile animals before and after methacholine (Mch)-induced changes in lung function. Five anesthetized, paralyzed, and thoracotomized piglets were studied before and during pulmonary vascular engor...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-0496(199801)25:1<45::aid-ppul5>

    authors: Wildhaber JH,Uhlig T,Sly PD

    更新日期:1998-01-01 00:00:00

  • Compliance in cystic fibrosis: an examination of infection control guidelines.

    abstract::The goal of this research was to begin the process of evaluating acceptability of infection control (IC) recommendations to CF patients and their families, determine whether compliance with IC guidelines differs from compliance with traditional CF medical treatment with respect to the variables predictive of complianc...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20781

    authors: Masterson T,Wildman BG,Newberry B,Omlor G,Bryson E,Kukay A

    更新日期:2008-05-01 00:00:00

  • Combination anti-inflammatory and antiviral therapy of influenza in a cotton rat model.

    abstract::The cotton rat was evaluated as a model for anti-inflammatory and antiviral influenza therapy. Beginning 3 days after intranasal infection with 10(7) tissue culture infectious doses-50% (TCID)(50) of an H3N2 human influenza, animals were treated topically via intranasal lavage with a range of doses of triamcinolone ac...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.10320

    authors: Ottolini M,Blanco J,Porter D,Peterson L,Curtis S,Prince G

    更新日期:2003-10-01 00:00:00

  • Continuous positive airway pressure by nasal prongs in bronchiolitis.

    abstract::Ten infants with evidence of impending respiratory failure from severe bronchiolitis were successfully treated with continuous positive airway pressure (NCPAP) with double nasal prongs. Their mean (SD) age was 6.7 (3.8) months and mean (SD) body weight was 7.1 (2.1) kg. Respiratory assessments were made immediately be...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章

    doi:10.1002/ppul.1950160305

    authors: Soong WJ,Hwang B,Tang RB

    更新日期:1993-09-01 00:00:00

  • Chronic cough and tonsillar hypertrophy: a case series.

    abstract::Two patients with intractable chronic cough were found to have tonsillar tissue impinging on their epiglottis. In both case, tonsillectomy was curative. The observations in these patients are consistent with a previous report indicating chronic cough from the uvula in contact with the epiglottis with cough cessation f...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20919

    authors: Gurgel RK,Brookes JT,Weinberger MM,Smith RJ

    更新日期:2008-11-01 00:00:00

  • Comparison of normal infants and infants with cystic fibrosis using forced expiratory flows breathing air and heliox.

    abstract::SUMMARY. The detection of early airway disease in infants with cystic fibrosis (CF) may lead to earlier intervention and an improved prognosis. We hypothesized that the ratio of maximal expiratory flows while breathing a mixture of helium and oxygen (heliox) and air, referred to as density dependence (DD), would ident...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/1099-0496(200101)31:1<17::aid-ppul1002>3.0

    authors: Davis S,Jones M,Kisling J,Howard J,Tepper RS

    更新日期:2001-01-01 00:00:00

  • Pediatric pulmonology year in review 2016: Part 2.

    abstract::Pediatric Pulmonology continues to publish research and clinical topics related to the entire range of children's respiratory disorders. As we have done annually in recent years, we here summarize some of the past year's publications in our major topic areas, as well as selected literature in these areas from other co...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,评审

    doi:10.1002/ppul.23719

    authors: Auten R,Ren C,Yilmaz O,Noah TL

    更新日期:2017-09-01 00:00:00

  • Exercise-induced stridor due to abnormal movement of the arytenoid area: videoendoscopic diagnosis and characterization of the "at risk" group.

    abstract::We evaluated 4 patients who developed severe, symptomatic stridor during maximal cardiopulmonary exercise testing, all referred due to exercise-related dyspnea. All underwent resting, unsedated transnasal fiberoptic laryngoscopy and had normal findings. Four patients performed repeat maximal exercise testing with fibe...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20076

    authors: Fahey JT,Bryant NJ,Karas D,Goldberg B,Destefano R,Gracco LC

    更新日期:2005-01-01 00:00:00

  • Changes in lung mechanics and histamine responsiveness after sequential canine adenovirus 2 and canine parainfluenza 2 virus infection in beagle puppies.

    abstract::We determined the effects of an immediately antecedent viral lower respiratory tract infection (LRI) on the severity of clinical illness, changes in lung function and airway histamine responsiveness produced by a subsequent LRI in 9-12 week old beagle puppies inoculated with canine adenovirus 2, followed in 2 weeks by...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950100403

    authors: Quan SF,Witten ML,Grad R,Ray CG,Lemen RJ

    更新日期:1991-01-01 00:00:00

  • Pulmonary sarcoidosis in children: serial evaluation of bronchoalveolar lavage cells during corticosteroid treatment.

    abstract::The clinical course of sarcoidosis in children has not been well defined. Eight children with symptomatic sarcoidosis included in this study underwent pulmonary function tests and bronchoscopy with bronchoalveolar lavage (BAL) before treatment and during steroid therapy. At the start of therapy, functional parameters,...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950160109

    authors: Chadelat K,Baculard A,Grimfeld A,Tournier G,Boule M,Boccon-Gibod L,Clement A

    更新日期:1993-07-01 00:00:00

  • Fraction of exhaled nitric oxide and wheezing phenotypes in preschool children.

    abstract:BACKGROUND:Asthma is a chronic lower airway inflammatory disease. Nitric oxide is an inflammatory mediator produced endogenously in the airway. Previous studies have demonstrated that the fractional concentration of exhaled nitric oxide (FeNO) is increased in asthma. OBJECTIVES:To investigate if FeNO concentrations we...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22705

    authors: Oh MA,Shim JY,Jung YH,Seo JH,Young Kim H,Kwon JW,Kim BJ,Kim HB,Kim WK,Lee SY,Jang GC,Song DJ,Kim HJ,Shin YJ,Park JW,Cho SH,Lee JS,Hong SJ

    更新日期:2013-06-01 00:00:00

  • Increased interleukin-8 and monocyte chemoattractant protein-1 concentrations in mechanically ventilated preterm infants with pulmonary hemorrhage.

    abstract::Pulmonary hemorrhage (PH) is a serious complication causing acute respiratory distress in the premature infant, and it is associated with significant mortality and morbidity. The role of inflammatory mediators in this condition is largely undefined. Serial tracheal aspirates (TA) were obtained at intervals from 65 mec...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.10141

    authors: Baier RJ,Loggins J,Kruger TE

    更新日期:2002-08-01 00:00:00

  • Pilot study for the development of a monitoring device for ventilated children.

    abstract::Airway pressure and air flow were measured at the endotracheal tube in 13 children on a variety of ventilators. These signals were stored for analysis on a computer. Further data sets were obtained after 24 hours or following major interventions. Air flow rate was integrated to give volume. Pulmonary resistance and el...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950110315

    authors: Wensley DF,Noonan P,Seear MD,Werner H,Pirie GE

    更新日期:1991-01-01 00:00:00

  • Non-invasive assessment of exercise performance in children with cystic fibrosis (CF) and non-cystic fibrosis bronchiectasis: is there a CF specific muscle defect?

    abstract:INTRODUCTION:Peripheral muscle dysfunction is increasingly recognized as complicating respiratory disease, but this is difficult to measure non-invasively. RESEARCH QUESTION:Can skeletal muscle function and efficiency be measured during exercise non-invasively using respiratory mass spectrometry (RMS); and is the know...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20899

    authors: Rosenthal M,Narang I,Edwards L,Bush A

    更新日期:2009-03-01 00:00:00

  • Protective effect of albuterol delivered via a spacer device (Babyhaler) against methacholine induced bronchoconstriction in young wheezy children.

    abstract::Nine young asthmatic children aged 2-5 years underwent methacholine challenge after placebo or albuterol administered by metered dose inhaler through a spacer device (Babyhaler) with a face mask in a double-blind, cross-over, randomized study. The methacholine challenge was performed using chest auscultation to define...

    journal_title:Pediatric pulmonology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1002/ppul.1950170503

    authors: Avital A,Godfrey S,Schachter J,Springer C

    更新日期:1994-05-01 00:00:00