Partitioning the respiratory effects of airway citric acid and normal saline in lambs.

abstract：:The gene that encodes for the cystic fibrosis transmembrane regulator protein (CFTR) was identified in 1989, yet major pathophysiologic questions remain unanswered. There is emerging evidence that CFTR is a bicarbonate channel, a driver of chloride-bicarbonate exchange and through its action on local pH, a regulator o...

journal_title：Pediatric pulmonology

authors： Borowitz D

更新日期：2015-10-01 00:00:00

abstract：:Severe bronchopulmonary dysplasia (BPD) is frequently associated with asthma. The combination is often severe enough to necessitate corticosteroid therapy. There are no commercially available nebulizer solutions of corticosteroids for use in infants and young children. Seven infants and small children with very severe...

journal_title：Pediatric pulmonology

authors： König P,Shatley M,Levine C,Mawhinney TP

更新日期：1992-08-01 00:00:00

abstract：:Pediatric lung transplantation has advanced over the years, providing a potential life-prolonging therapy to patients with cystic fibrosis. Despite this, many challenges in lung transplantation remain and result in worse outcomes than other solid organ transplants. As CF lung disease progresses, children and their car...

journal_title：Pediatric pulmonology

authors： Dellon E,Goldfarb SB,Hayes D Jr,Sawicki GS,Wolfe J,Boyer D

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:To describe and analyze the characteristics and the early risk factors for mortality of noninvasive ventilation (NIV) in critically ill children. STUDY DESIGN:A multicenter, prospective, observational 2-year study carried out with critically ill patients (1 month - 18 years of age) who needed NIV. Clinical d...

journal_title：Pediatric pulmonology

authors： López J,Pons-Òdena M,Medina A,Molinos-Norniella C,Palanca-Arias D,Demirkol D,León-González JS,López-Fernández YM,Perez-Baena L,López-Herce J,NIV Research Group.

更新日期：2020-12-31 00:00:00

abstract：OBJECTIVES:First, create a clinical severity score for patients with chronic lung disease of infancy (CLDi) following neonatal intensive care unit (NICU) stay. Second, using California wide population-based data, identify factors associated with clinical severity of CLDi at 4-9 months corrected gestational age (CGA). ...

journal_title：Pediatric pulmonology

authors： Gage S,Kan P,Oehlert J,Gould JB,Stevenson DK,Shaw GM,O'Brodovich HM

更新日期：2015-09-01 00:00:00

abstract：:A 14-year-old Korean boy was admitted with cough, hemoptysis, and fever. A chest X-ray showed a solitary pulmonary mass and pneumonitis. Bronchial biopsy by fiberoptic bronchoscopy revealed a poorly differentiated small cell carcinoma. All of the staging information indicated that the patient had limited disease. Duri...

journal_title：Pediatric pulmonology

authors： Kim CK,Chung CY,Koh YY

更新日期：2000-04-01 00:00:00

abstract：:Acute mycoplasma pneumonia may be accompanied by wheeze in some children considered not to have asthma. The aim of the present study was to evaluate cytokine secretion in children with acute mycoplasma pneumonia and wheeze. We studied 58 patients with mycoplasma pneumonia (12 with wheeze, Group 1; 46 without wheeze, G...

journal_title：Pediatric pulmonology

authors： Choi IS,Byeon JH,Yoo Y,Lee KC,Choung JT

更新日期：2009-05-01 00:00:00

abstract：:Fetuses of diabetic mothers who were exposed to excessive glucose show delayed maturation. Under these conditions, altered growth factor expression or signaling may have important regulatory influences. We examined the role of epidermal growth factor (EGF) in lung development and maternal diabetes in the rat. In order...

journal_title：Pediatric pulmonology

authors： Thulesen J,Poulsen SS,Nexø E,Raaberg L

更新日期：2000-02-01 00:00:00

abstract：:Home mattresses of 24 asthmatic children with house dust mite allergy were sprayed with either benzyl-benzoate foam or placebo in a double blind fashion, 10 days before the children left the residential house for asthmatic children Istituto Pio XII (located in the Italian Alps in an environment free of mites) and went...

journal_title：Pediatric pulmonology

authors： Sette L,Comis A,Marcucci F,Sensi L,Piacentini GL,Boner AL

更新日期：1994-10-01 00:00:00

abstract：:The aim of this study was to validate our Dalhousie Dyspnea Scales in children referred for histamine bronchoprovocation challenge. Seventy-four children rated their dyspnea after each FEV(1) measurement following inhalation of doubling histamine concentrations from 0.125 to 8.0 mg/ml by the standard tidal breathing m...

journal_title：Pediatric pulmonology

authors： Pianosi P,Smith CP,Almudevar A,McGrath PJ

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Pneumonia is a leading killer of children under-5 years, with a high burden in Nigeria. We aimed to quantify the regional burden and risks of pediatric pneumonia in Nigeria, and specifically the states of Lagos and Jigawa. METHODS:We conducted a scoping literature search for studies of pneumonia morbidity a...

journal_title：Pediatric pulmonology

authors： Iuliano A,Aranda Z,Colbourn T,Agwai IC,Bahiru S,Bakare AA,Burgess RA,Cassar C,Shittu F,Graham H,Isah A,McCollum ED,Falade AG,King C,On Behalf Of The Inspiring Project Consortium

更新日期：2020-06-01 00:00:00

abstract：:The pediatric pneumogram is a frequently used tool in the diagnosis and management of apnea during infancy. We analyzed 287 pneumographic recordings from 123 full-term infants (63 males) obtained during the first 12 months of life to establish normative values for apnea, periodic breathing, and bradycardia. The result...

journal_title：Pediatric pulmonology

authors： Kelly DH,Stellwagen LM,Kaitz E,Shannon DC

更新日期：1985-07-01 00:00:00

abstract：:C-reactive protein (CRP) concentrations were evaluated in 9 cystic fibrosis (CF) patients with acute pulmonary exacerbations and 14 patients with acute exacerbations of asthma without any symptoms of an acute infection. CRP concentrations were serially evaluated over the course of therapy in CF patients and compared w...

journal_title：Pediatric pulmonology

authors： Friesen CA,Wiens LA,Burry VF,Portnoy J,Roberts CC

更新日期：1995-10-01 00:00:00

abstract：OBJECTIVE:Methicillin-resistant Staphylococcus aureus (MRSA) infections in cystic fibrosis (CF) patients have greatly increased in prevalence in the past two decades and may lead to a more rapid rate of lung function decline. The objective of this study was to determine the impact of a MRSA eradication protocol on long...

journal_title：Pediatric pulmonology

authors： Belarski E,Pettit R

更新日期：2020-03-01 00:00:00

abstract：:The assessment of apnea and asynchronous breathing requires the application of a facemask connected to a pneumotachograph and inductive transducer bands placed around the chest wall. These contact devices may alter the breathing pattern and are difficult to implement, especially in infants and children. This study val...

journal_title：Pediatric pulmonology

authors： Goldman LJ

更新日期：2012-05-01 00:00:00

abstract：:Neurally adjusted ventilatory assistance (NAVA) can overcome technical difficulties with synchronizing noninvasive ventilation breaths with the patient, a modality often used in very low birthweight infants (VLBW) with apnea of prematurity (AOP). This study is a retrospective single-center investigation into whether N...

journal_title：Pediatric pulmonology

authors： Tabacaru CR,Moores RR Jr,Khoury J,Rozycki HJ

更新日期：2019-11-01 00:00:00

abstract：:We present a child with interstitial lung disease (ILD) who was diagnosed with desquamative interstitial pneumonitis following CT thorax and open lung biopsy aged 2 years. Subsequently, surfactant protein gene analysis revealed mutations in the ABCA3 gene. This case of ABCA3 deficient ILD describes a stable clinical c...

journal_title：Pediatric pulmonology

authors： Williamson M,Wallis C

更新日期：2014-03-01 00:00:00

abstract：:Atrial natriuretic peptide (ANP) has known natriuretic, diuretic, and vasodilatatory effects. It is synthesized and stored in the atrial cells. Stretching of the atrial muscle fibers during an increase in venous return sets a response of ANP release into the blood stream. High levels of ANP were measured in a number o...

journal_title：Pediatric pulmonology

authors： Haviv M,Haver E,Lichtstein D,Hurvitz H,Klar A

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND/OBJECTIVE:Our objective was to obtain follow-up pulmonary function testing and assessment of clinical respiratory outcomes, at 1-2 years, in preterm infants whose mothers were randomized to a single rescue course of antenatal steroids (AS) versus placebo. METHODS:Follow-up of a randomized, double-blinded tr...

journal_title：Pediatric pulmonology

authors： McEvoy C,Schilling D,Spitale P,O'Malley J,Bowling S,Durand M

更新日期：2017-09-01 00:00:00

abstract：INTRODUCTION:The efficacy of nebulized hypertonic saline (HS) therapy for shortening hospital length of stay (LOS) or improving bronchiolitic symptoms remains controversial. Most studies enrolled small numbers of subjects and did not consider the role of respiratory syncytial virus (RSV), the most common cause of acute...

journal_title：Pediatric pulmonology

authors： Morikawa Y,Miura M,Furuhata MY,Morino S,Omori T,Otsuka M,Chiga M,Obonai T,Hataya H,Kaneko T,Ishikura K,Honda M,Hasegawa Y,Tokyo Pediatric Clinical Research Network.

更新日期：2018-03-01 00:00:00

abstract：:Cystic fibrosis (CF) is an autosomal recessive disease. It affects multiple body organs. The lungs and pancreas are the most affected which results in progressive lung damage and pancreatic insufficiency. Due to the disease process, CF patients require significantly higher caloric intake than recommended for other ind...

journal_title：Pediatric pulmonology

authors： Nasr SZ,Drury D

更新日期：2008-03-01 00:00:00

abstract：:Epidemiological data suggest that respiratory syncytial virus (RSV) infection in early life is a risk factor for later asthma. There are no prospective studies on RSV infection starting from infancy progressing through childhood into adulthood. We followed up a cohort of children, hospitalized for RSV bronchiolitis or...

journal_title：Pediatric pulmonology

authors： Korppi M,Piippo-Savolainen E,Korhonen K,Remes S

更新日期：2004-08-01 00:00:00

abstract：INTRODUCTION:Acute bronchiolitis is a major cause of acute respiratory distress in infants. The soluble receptor for advanced glycation end-products (sRAGE) is a biomarker of pulmonary damage processes, with a diagnostic and a prognostic value in acute respiratory distress syndrome (ARDS). The RAGE pathway is also impl...

journal_title：Pediatric pulmonology

authors： Egron C,Roszyk L,Rochette E,Jabaudon M,Sapin V,Mulliez A,Labbé A,Coste K

更新日期：2018-10-01 00:00:00

abstract：:The purpose of the study was to analyze the respiratory-dependent intraarterial blood pressure variations (pulsus paradoxus, PP) in intensive care unit patients with obstructive and restrictive pulmonary disease, and to evaluate the usefulness of PP for assessment of disease severity. One-minute paper recordings of ar...

journal_title：Pediatric pulmonology

authors： Frey B,Freezer N

更新日期：2001-02-01 00:00:00

abstract：:Our objective was to determine the repeatability of bronchial responsiveness to mannitol dry powder (MDP) as an objective marker of asthma in children. MDP challenge was performed in children with stable asthma at the same time of the day on two separate occasions within a week. The test was terminated after a 15% fal...

journal_title：Pediatric pulmonology

authors： Barben J,Roberts M,Chew N,Carlin JB,Robertson CF

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To evaluate the contents of parent-created emergency tracheostomy kits and identify deficiencies. METHODS:This was an observational study. Data on emergency tracheostomy kits were abstracted for 30 consecutive children who had a tracheostomy tube in situ during an outpatient clinic visit with the Division of...

journal_title：Pediatric pulmonology

authors： Amin R,Zabih W,Syed F,Polyviou J,Tran T,Propst EJ,Holler T

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:Severe inflammation plays a vital role in the pathogenesis of meconium aspiration syndrome (MAS). Intratracheal (IT) instillation of corticosteroids may be beneficial for MAS in optimizing local effect and reducing systemic adverse effects, but the optimum dosing course remains open to question. METHODS:Thi...

journal_title：Pediatric pulmonology

authors： Lin CH,Jeng MJ,Yang YC,Hsiao YH,Kou YR

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Interferon-gamma (IFN-γ) and interferon-inducible protein of 10 kDa (IP-10) are potent inflammatory mediators and contribute to acute lung injury in adults. Recently, a potential role for IFN-γ and IP-10 in the pathogenesis of bronchopulmonary dysplasia (BPD) has been reported in animal models. OBJECTIVE:To...

journal_title：Pediatric pulmonology

authors： Aghai ZH,Saslow JG,Mody K,Eydelman R,Bhat V,Stahl G,Pyon K,Bhandari V

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Improper use of asthma inhalers is one of the potential factors of poor asthma control among children. This study aimed to assess the proper handling of asthma inhalers and asthma control in addition to factors influencing them among pediatric patients who self-administer their inhalers. METHODS:A cross-sec...

journal_title：Pediatric pulmonology

authors： Almomani BA,Al-Qawasmeh BS,Al-Shatnawi SF,Awad S,Alzoubi SA

更新日期：2021-01-26 00:00:00

abstract：BACKGROUND:Gastro-esophageal reflux (GOR) may contribute to lung disease in children with cystic fibrosis (CF). There is conflicting evidence regarding the effect of chest physiotherapy (CPT) in the head-down position on GOR. Furthermore, there is currently no evidence on the impact of physiotherapy on GOR as assessed ...

journal_title：Pediatric pulmonology

authors： Doumit M,Krishnan U,Jaffé A,Belessis Y

更新日期：2012-02-01 00:00:00