Early factors related to mortality in children treated with bi-level noninvasive ventilation and CPAP.

abstract：OBJECTIVE:Telomere length is associated with poorer lung health in older adults, possibly from cumulative risk factor exposure, but data are lacking in pediatric and population-based cohorts. We examined associations of telomere length with lung function in children and mid-life adults. METHODS:Data were drawn from a ...

journal_title：Pediatric pulmonology

authors： Nguyen MT,Saffery R,Burgner D,Lycett K,Vryer R,Grobler A,Dwyer T,Ranganathan S,Wake M

更新日期：2019-12-01 00:00:00

abstract：:Pulmonary hemorrhage (PH) is a serious complication causing acute respiratory distress in the premature infant, and it is associated with significant mortality and morbidity. The role of inflammatory mediators in this condition is largely undefined. Serial tracheal aspirates (TA) were obtained at intervals from 65 mec...

journal_title：Pediatric pulmonology

authors： Baier RJ,Loggins J,Kruger TE

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:In cystic fibrosis (CF), the spectrum and frequency of CFTR variants differ by geography and race/ethnicity. CFTR variants in White patients are well-described compared with Latino patients. No studies of CFTR variants have been done in patients with CF in the Dominican Republic or Puerto Rico. METHODS:CFTR...

journal_title：Pediatric pulmonology

authors： Zeiger AM,McGarry ME,Mak ACY,Medina V,Salazar S,Eng C,Liu AK,Oh SS,Nuckton TJ,Jain D,Blackwell TW,Kang HM,Abecasis G,Oñate LC,Seibold MA,Burchard EG,Rodriguez-Santana J

更新日期：2020-02-01 00:00:00

abstract：:Our aim was to determine whether antenatal corticosteroids improve perinatal adaptation of the pulmonary circulation in lambs with lung hypoplasia (LH). LH was induced in 12 ovine fetuses between 105 and 140 days gestation (term approximately 147 days); in 6 of these the ewe was given a single dose of betamethasone (1...

journal_title：Pediatric pulmonology

authors： Suzuki K,Hooper SB,Wallace MJ,Probyn ME,Harding R

更新日期：2006-09-01 00:00:00

abstract：:There is a need to judge general exercise tolerance in children with cystic fibrosis (CF) under normal daily activity conditions and -when more extensive testing is required-in an exercise laboratory in a specialized center. We investigated the reproducibility, validity, and criterion for a 6-minute walking test, whic...

journal_title：Pediatric pulmonology

authors： Gulmans VA,van Veldhoven NH,de Meer K,Helders PJ

更新日期：1996-08-01 00:00:00

abstract：:During the final prenatal period of fetal lung development in humans, important maturational processes occur, including the production of surfactant necessary to decrease surface tension at the air-liquid interface of the alveoli. During early gestation, the glucocorticoid receptor is expressed in the fetal lung, and ...

journal_title：Pediatric pulmonology

authors： Bolt RJ,van Weissenbruch MM,Lafeber HN,Delemarre-van de Waal HA

更新日期：2001-07-01 00:00:00

abstract：:The reliability and predictive value of salivary theophylline levels was investigated in 58 children who were treated with oral sustained-release theophylline preparations for bronchial asthma. Serum and saliva levels were assessed by fluorescence polarization immunoassay (FPIA), and Seralyzer (reagent strip reflectan...

journal_title：Pediatric pulmonology

authors： Schulte T,Buhr W,Schmidt M,Walkenbach A,Berdel D

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Hypoxia and reactive oxygen species (ROS) including H(2)O(2) play major roles in triggering and progression of pulmonary vascular remodeling in persistent pulmonary hypertension. Catalase (CAT), the major endogenous enzyme scavenging H(2)O(2), is regulated in a tissue- and context-specific manner. OBJECTIVE...

journal_title：Pediatric pulmonology

authors： Awad H,Nolette N,Hinton M,Dakshinamurti S

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:Lung disease in cystic fibrosis (CF) begins early in life but the capabilities for detecting abnormalities of pulmonary dysfunction in children remain limited. OBJECTIVE:The study aimed to evaluate the early progression of lung function by the analysis of pulmonary hyperinflation, ventilation inhomogeneit...

journal_title：Pediatric pulmonology

authors： Walicka-Serzysko K,Postek M,Milczewska J,Sands D

更新日期：2020-11-01 00:00:00

abstract：:Airway inflammation of eosinophilic asthma (EA) attributes to Th2 response, leaving the role of Th17 response unknown. Signal transducer and activator of transcription 3 (STAT3) induce both suppressors of cytokine signaling 3 (SOCS3) and retinoic acid receptor-related orphan nuclear receptor γ (RORγt) to initiate Th17...

journal_title：Pediatric pulmonology

authors： Lin X,Lv J,Ge D,Bai H,Yang Y,Wu J

更新日期：2020-06-01 00:00:00

abstract：:Follow-up studies have demonstrated that bronchiolitis caused by respiratory syncytial virus (RSV) is strongly associated with wheezing in the ensuing years. During the acute infection the immune response may induce long-lasting detrimental effects, thereby contributing to post-bronchiolitis wheezing (PBW). Therefore,...

journal_title：Pediatric pulmonology

authors： van Woensel JB,Kimpen JL,Sprikkelman AB,Ouwehand A,van Aalderen WM

更新日期：2000-08-01 00:00:00

abstract：INTRODUCTION:Acute bronchiolitis is a major cause of acute respiratory distress in infants. The soluble receptor for advanced glycation end-products (sRAGE) is a biomarker of pulmonary damage processes, with a diagnostic and a prognostic value in acute respiratory distress syndrome (ARDS). The RAGE pathway is also impl...

journal_title：Pediatric pulmonology

authors： Egron C,Roszyk L,Rochette E,Jabaudon M,Sapin V,Mulliez A,Labbé A,Coste K

更新日期：2018-10-01 00:00:00

abstract：:A thorough understanding of the early natural history of cystic fibrosis (CF) lung disease is critical for the development of effective interventions in the youngest patients. We assessed the evolution of pulmonary infection, inflammation, and clinical course among 40 infants over a 2-year period through annual bronch...

journal_title：Pediatric pulmonology

authors： Rosenfeld M,Gibson RL,McNamara S,Emerson J,Burns JL,Castile R,Hiatt P,McCoy K,Wilson CB,Inglis A,Smith A,Martin TR,Ramsey BW

更新日期：2001-11-01 00:00:00

abstract：OBJECTIVES:We evaluated safety and efficacy of recombinant human growth hormone (rhGH) for improving growth, lean body mass (LBM), pulmonary function, and exercise tolerance in children with cystic fibrosis (CF) and growth restriction. STUDY DESIGN:Multicenter, open-label, controlled clinical trial comparing outcomes ...

journal_title：Pediatric pulmonology

authors： Stalvey MS,Anbar RD,Konstan MW,Jacobs JR,Bakker B,Lippe B,Geller DE

更新日期：2012-03-01 00:00:00

abstract：:Neonatal exposure to intermittent hypoxia results in altered ventilatory response to subsequent hypoxia in animal models. The effect of similar exposure in human infants is unknown. Our objective was to determine the impact of sleep disordered breathing (SDB) in early infancy on ventilatory response in infants. We rec...

journal_title：Pediatric pulmonology

authors： MacLean JE,Tan S,Fitzgerald DA,Waters KA

更新日期：2013-03-01 00:00:00

abstract：:The structure, distribution, and frequency of neuroendocrine (NE) cells in human fetal lung from early stages of development to term are described. Neuroendocrine cells were studied by electron microscopy and immunostaining for serotonin and bombesin, recently identified markers of these cells in human lung. The diffe...

journal_title：Pediatric pulmonology

authors： Cutz E,Gillan JE,Bryan AC

更新日期：1985-05-01 00:00:00

abstract：:Exposure to chronic constant or intermittent hypoxia (CCH or CIH) may have different effects on growth and development in early life. In this work, we exposed postnatal day 2 (P2) CD1 mice to CCH or CIH (11% O2) for 4 weeks and examined the effect of hypoxia on body and organ growth until P30. Regression analysis show...

journal_title：Pediatric pulmonology

authors： Farahani R,Kanaan A,Gavrialov O,Brunnert S,Douglas RM,Morcillo P,Haddad GG

更新日期：2008-01-01 00:00:00

abstract：:Pneumatoceles and bronchiectasis are secondary complications of respiratory infections in patients with hyper IgE syndrome (HIgES). We report on a patient with HIgES and recurrent pneumonias since 1 year of age, with progression to pneumatoceles and bronchiectasis and fatal outcome, with disseminated infection and sus...

journal_title：Pediatric pulmonology

authors： Roxo P Jr,Torres LA,Menezes UP,Melo JM

更新日期：2013-01-01 00:00:00

abstract：:Over the past year, a series of papers have reviewed the literature concerning assessment and interpretation of lung function in infants and young children with chronic lung disease of infancy. This manuscript, which represents the final paper in that series, summarizes the findings to date and highlights key areas fo...

journal_title：Pediatric pulmonology

authors： Stocks J,Coates A,Bush A

更新日期：2007-01-01 00:00:00

abstract：:Neutrophil elastase is present at high levels in airway fluid of patients with cystic fibrosis (CF), and is responsible for considerable inflammatory damage. Human monocyte/neutrophil elastase inhibitor (MNEI), a 42-kDa serpin protein, is an effective inhibitor of neutrophil elastase, cathepsin G, and proteinase-3, re...

journal_title：Pediatric pulmonology

authors： Woods DE,Cantin A,Cooley J,Kenney DM,Remold-O'Donnell E

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Premature neonates frequently require oxygen supplementation as a therapeutic intervention that, while necessary, also exposes the lung to significant oxidant stress. We hypothesized that hyperoxia has a deleterious effect on alveolar epithelial barrier function rendering the neonatal lung susceptible to inj...

journal_title：Pediatric pulmonology

authors： Vyas-Read S,Vance RJ,Wang W,Colvocoresses-Dodds J,Brown LA,Koval M

更新日期：2018-01-01 00:00:00

abstract：:Since July 1988, a total of 92 transbronchial biopsies (TBB) have been performed in 18 patients (aged 3-16 years). Twelve patients (67%) were heart-lung transplant (HLT) recipients undergoing surveillance for pulmonary graft rejection and infection. The remainder included immunocompromised patients at risk of opportun...

journal_title：Pediatric pulmonology

authors： Whitehead B,Scott JP,Helms P,Malone M,Macrae D,Higenbottam TW,Smyth RL,Wallwork J,Elliott M,de Leval M

更新日期：1992-04-01 00:00:00

abstract：:There is no consensus about reproducibility and reliability of spirometry in young children. We evaluated forced expiratory maneuvers from 98 children aged 3 to 5 years with a variety of respiratory disorders before and after bronchodilator treatment. Forced vital capacity (FVC) and forced expiratory volume in 1 sec (...

journal_title：Pediatric pulmonology

authors： Kanengiser S,Dozor AJ

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:The pH of exhaled breath condensate (EBC) of adolescent athletes engaged in vigorous physical activity is low compared to healthy controls; however, the ionic determinants of EBC pH and the acute effects of exercise on those determinants have not been definitively established. OBJECTIVES:This study had two ...

journal_title：Pediatric pulmonology

authors： Greenwald R,Ferdinands JM,Teague WG

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVES:To identify the spirometric equations that are most appropriate for use in children and adolescents living in Bogota, Colombia after evaluating a set of relevant previously-developed equations, including the Global Lung Function Initiative (GLI) 2012 spirometry reference equations. METHODS:Healthy children ...

journal_title：Pediatric pulmonology

authors： Aristizabal-Duque R,Castiblanco E,Rodriguez I,Sossa-Briceño MP,Rodriguez-Martinez CE

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To carry out a cost-effectiveness analysis of omitting chest radiography in the diagnosis of infant bronchiolitis. HYPOTHESIS:Omitting chest radiographs in the diagnosis of typical bronchiolitis was expected to reduce costs without adversely affecting the detection rate of alternate diseases. STUDY DESIGN:A...

journal_title：Pediatric pulmonology

authors： Yong JH,Schuh S,Rashidi R,Vanderby S,Lau R,Laporte A,Nauenberg E,Ungar WJ

更新日期：2009-02-01 00:00:00

abstract：:We developed a simple method to identify neonates at high risk of bronchopulmonary dysplasia (BPD) and determined whether early (8 hours) and late (14 days) risk assessment is equally useful. A retrospective cohort design was utilized of subjects enrolled in multi-dose surfactant trials to develop each risk identifica...

journal_title：Pediatric pulmonology

authors： Rozycki HJ,Narla L

更新日期：1996-06-01 00:00:00

abstract：INTRODUCTION:Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders characterized by tissue deposition of glycosaminoglycans (GAG). Their musculoskeletal abnormalities and the GAG storage in the airway result in increased risk for patients undergoing anesthesia. This study evaluates a multi-disciplinary...

journal_title：Pediatric pulmonology

authors： Muhlebach MS,Shaffer CB,Georges L,Abode K,Muenzer J

更新日期：2013-06-01 00:00:00

abstract：:We determined the effects of an immediately antecedent viral lower respiratory tract infection (LRI) on the severity of clinical illness, changes in lung function and airway histamine responsiveness produced by a subsequent LRI in 9-12 week old beagle puppies inoculated with canine adenovirus 2, followed in 2 weeks by...

journal_title：Pediatric pulmonology

authors： Quan SF,Witten ML,Grad R,Ray CG,Lemen RJ

更新日期：1991-01-01 00:00:00

abstract：:We present two infants with congenital tracheal stenosis with complete tracheal rings. Both had associated congenital anomalies. The first case showed cardiac malformations, and the second case had agenesis of the right lung. We review the literature, in particular with reference to tracheal stenosis and pulmonary age...

journal_title：Pediatric pulmonology

authors： Voland JR,Benirschke K,Saunders B

更新日期：1986-07-01 00:00:00