Abstract:
:The purpose of the study was to analyze the respiratory-dependent intraarterial blood pressure variations (pulsus paradoxus, PP) in intensive care unit patients with obstructive and restrictive pulmonary disease, and to evaluate the usefulness of PP for assessment of disease severity. One-minute paper recordings of arterial blood pressures, left atrial pressures (LAP, 16 patients), breathing cycles, and electrocardiograms (ECG) were taken in 54 nonintubated children. There was a close relationship between systolic and diastolic blood pressure variations (r = 0.92). The mean coefficient of variation of PP was 18.4% (SD 11.6%). The relationship between respiratory dependent LAP fluctuations (Delta LAP) and PP was logarithmic. PP correlated significantly with a respiratory severity score (RSS: wheeze, oxygen requirement, heart rate, arterial partial pressure of carbon dioxide) in a subgroup of 16 asthmatics (r = 0.66, P = 0.005); wheeze score was the only true independent determinant of RSS (multiple regression). In the nonasthmatics with restrictive lung disease, the correlation coefficient for the association between PP and RSS was 0.34 (P = 0.08), with a significant univariate correlation between PP and wheeze score (r = 0.62, P = 0.001). We conclude that PP correlates significantly with wheeze in obstructive and restrictive disease. PP is a valuable clinical sign of disease severity in patients with wheeze as clinical manifestation of obstructive airway disease. The relationship between Delta LAP and PP confirms the finding that an increase in PP is associated with a rise in left atrial transmural pressure.
journal_name
Pediatr Pulmonoljournal_title
Pediatric pulmonologyauthors
Frey B,Freezer Ndoi
10.1002/1099-0496(200102)31:2<138::aid-ppul1022>3.subject
Has Abstractpub_date
2001-02-01 00:00:00pages
138-43issue
2eissn
8755-6863issn
1099-0496pii
10.1002/1099-0496(200102)31:2<138::AID-PPUL1022>3.journal_volume
31pub_type
杂志文章abstract:BACKGROUND:In preschool children, measurement of airway resistance using interrupter technique (Rint) is feasible to assess the degree of bronchial obstruction. Although some studies measured Rint in infancy, values of Rint and its variability in preterm infants are unknown. In this study, Rint and its variability was ...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23771
更新日期:2017-10-01 00:00:00
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journal_title:Pediatric pulmonology
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doi:10.1002/ppul.23559
更新日期:2016-12-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.1950010305
更新日期:1985-05-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/(sici)1099-0496(199712)24:6<391::aid-ppul3
更新日期:1997-12-01 00:00:00
abstract:PURPOSE:To examine the independent association of asthma and obesity and of their co-existence with functional exercise capacity among urban adolescents. METHODS:One hundred eighteen Hispanic- and African-American adolescents including 33 obese asthmatics, 18 normal-weight asthmatics, 38 obese non-asthmatics, and 29 n...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.22547
更新日期:2012-11-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章,随机对照试验
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更新日期:2005-05-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.24622
更新日期:2020-03-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.22867
更新日期:2014-06-01 00:00:00
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pub_type: 杂志文章,评审
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更新日期:2001-06-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20403
更新日期:2006-06-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.22593
更新日期:2013-03-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1002/ppul.21287
更新日期:2010-10-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章,随机对照试验
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更新日期:2006-03-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23947
更新日期:2018-03-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.21277
更新日期:2010-09-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章
doi:10.1002/ppul.20129
更新日期:2005-01-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
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更新日期:1992-03-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.10409
更新日期:2004-02-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
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更新日期:2015-12-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.22976
更新日期:2014-03-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23369
更新日期:2016-08-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
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更新日期:2019-11-01 00:00:00
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pub_type: 杂志文章
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更新日期:1989-01-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章
doi:10.1002/ppul.10325
更新日期:2003-09-01 00:00:00
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journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23636
更新日期:2017-02-01 00:00:00