Abstract:
:Pediatric lung transplantation has advanced over the years, providing a potential life-prolonging therapy to patients with cystic fibrosis. Despite this, many challenges in lung transplantation remain and result in worse outcomes than other solid organ transplants. As CF lung disease progresses, children and their caregivers are often simultaneously preparing for lung transplantation and end of life. In this article, we will discuss the current barriers to success in pediatric CF lung transplantation as well as approaches to end of life care in this population.
journal_name
Pediatr Pulmonoljournal_title
Pediatric pulmonologyauthors
Dellon E,Goldfarb SB,Hayes D Jr,Sawicki GS,Wolfe J,Boyer Ddoi
10.1002/ppul.23748subject
Has Abstractpub_date
2017-11-01 00:00:00pages
S61-S68issue
S48eissn
8755-6863issn
1099-0496journal_volume
52pub_type
杂志文章,评审abstract::A 16-year-old female with cystic fibrosis (CF) presented with an acute respiratory exacerbation during which black flecks were observed in the spontaneously expectorated sputum. The production of this pigmented sputum was subsequently attributed to Exophiala dermatitidis hyphae. Treatment with antibiotics, corticoster...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.21187
更新日期:2010-05-01 00:00:00
abstract::"Pulmonary Interstitial Glycogenosis: Diagnostic Evaluation and Clinical Course," written by Liptzin et al is a timely and insightful phenotypic summary of a rare pediatric interstitial lung disease. Twenty-four infants with biopsy-proven pulmonary interstitial glycogenosis (PIG) were reviewed at their center. Genetic...
journal_title:Pediatric pulmonology
pub_type: 评论,杂志文章
doi:10.1002/ppul.24167
更新日期:2018-12-01 00:00:00
abstract::There is a subpopulation of asthmatic patients with a history of life-threatening asthma (LTA) who have a reduced perception of respiratory loads. The aim of this study was to determine if these patients have a reduced perception of both intrinsic and extrinsic loads. Children with asthma were classified into life-thr...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.10199
更新日期:2002-12-01 00:00:00
abstract::Traumatic injuries to the pediatric trachea are uncommon events that require prompt diagnosis and management. When they do occur, tracheal injuries often arise in the setting of high impact trauma and are accompanied by major injuries to other organ systems. In this report, we present the diagnosis and conservative ma...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23507
更新日期:2017-01-01 00:00:00
abstract::Randomized trials of ribavirin therapy have used clinical scores to assess illness severity. Little information on agreement for these findings between observers has been published. We decided to determine interobserver agreement for (1) a history for apnea or respiratory failure; (2) assessment of cyanosis, respirato...
journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1002/(SICI)1099-0496(199607)22:1<23::AID-PPUL4>
更新日期:1996-07-01 00:00:00
abstract:INTRODUCTION:There are few published data on the efficacy of systemic corticosteroids in preterm infants with very severe forms of bronchopulmonary dysplasia (BPD), requiring respiratory support after 3 months of age. The aim of this study was to report the use of pulses of methylprednisolone in this population and its...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.25109
更新日期:2021-01-01 00:00:00
abstract::Cystic fibrosis (CF) is an illness associated with high healthcare utilization and healthcare costs, even when compared to other chronic illnesses. In a variety of medical populations, depression has been found to be associated with lower adherence and poorer medical outcomes. The current study is a retrospective char...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.22990
更新日期:2014-12-01 00:00:00
abstract::Indoor aeroallergen exposures increased asthma symptoms in Caucasians, but their determinants and relationship to asthma and allergy in Asians are unclear. This study investigated exposures to cat, cockroach, and Blomia tropicalis allergens in 115 Hong Kong families with asthmatic children. Patients underwent exhaled ...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.21391
更新日期:2011-07-01 00:00:00
abstract:OBJECTIVE:To develop and validate a questionnaire to assess asthma control in children (CAN). DESIGN:Two versions of the CAN (for carers and children) were developed. Both versions were validated in an observational, prospective, multicenter study performed in 38 hospital outpatient clinics throughout Spain. Four hund...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20929
更新日期:2009-01-01 00:00:00
abstract::We assessed the safety and use of induced sputum (IS) in children with cystic fibrosis (CF). Forty-eight children (19 males) with CF, mean age 12.6 (range, 7.3-17.0) years and median forced expired volume in 1 sec (FEV(1)) 48% (range, 14-77%) predicted were recruited. Patients spontaneously expectorated sputum and the...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.10226
更新日期:2003-04-01 00:00:00
abstract:OBJECTIVE:The aim of this study was to assess pulmonary function and its predictors in very low birth weight (birth weight ≤1,500 g) children (VLBWc) with or without bronchopulmonary dysplasia (BPD), born at gestational age ≤32 weeks at a single tertiary center during 1996-1999, after the introduction of surfactant the...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.22676
更新日期:2013-08-01 00:00:00
abstract::Pulmonary sequestration is a rare anomaly and is conventionally treated with surgical excision. This report describes the successful occlusion of a large aberrant artery to an intralobar pulmonary sequestration using an Amplatzer Vascular Plug. ...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20882
更新日期:2008-09-01 00:00:00
abstract::Pulmonary function and exercise tolerance were evaluated in late childhood in two groups of prematurely born children: one group with bronchopulmonary dysplasia (BPD) [n = 15; gestational age at birth (GA): 29.6 +/- 2.8 weeks; birth weight (BW): 1,367 +/- 548 g; age at test: 7.9 +/- 0.6 years], and a second group with...
journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章
doi:10.1002/ppul.1950200506
更新日期:1995-11-01 00:00:00
abstract::A microbe-specific diagnosis in community-acquired pneumonia (CAP) is difficult in children, and studies on nonspecific chest radiographic and host response markers have been inconsistent. Serum procalcitonin (PCT) is a newly recognized, promising marker for differentiating between bacterial and viral infections. Seru...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.10201
更新日期:2003-01-01 00:00:00
abstract::The goal of the present investigation was to describe the prevalence of and clinical factors associated with sleep-disordered breathing in children and adolescents. Children and adolescents (3,680 in all, 1-18 years old) attending schools in central Greece were surveyed by questionnaires distributed to parents. We fou...
journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章
doi:10.1002/ppul.20002
更新日期:2004-06-01 00:00:00
abstract:BACKGROUND:Social and family factors may influence the probability of achieving asthma control in children. Parents' quality of life has been insufficiently explored as a predictive factor linked to the probability of achieving disease control in asthmatic children. OBJECTIVE:Determine whether the parents' quality of ...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23336
更新日期:2016-07-01 00:00:00
abstract::We recently reported that prenatal glucocorticoid therapy is less effective at promoting an improvement in lung function in male than in female sheep. This observation, and the higher incidence of respiratory distress syndrome in human males, suggests that the male fetal lung may be less responsive to glucocorticoids ...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.1082
更新日期:2001-07-01 00:00:00
abstract::Pneumocyte apoptosis is implicated in the pathophysiology of acute inflammatory lung injuries in newborns and adults. Pulmonary angiotensin (ANG) II contributes to lung epithelial apoptosis in vitro, but its role in acute lung injury in vivo is unclear. We therefore studied the effects of ANG II receptor action on the...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20187
更新日期:2005-04-01 00:00:00
abstract::Thirteen children with asthma were treated with cumulative doses of terbutaline delivered as a pressurized aerosol and from a new multidose powder inhaler (Turbuhaler) in a randomized cross-over dose-response study. The cumulative dose of terbutaline was 2 mg on each study day. All children used a correct aerosol inha...
journal_title:Pediatric pulmonology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1002/ppul.1950070211
更新日期:1989-01-01 00:00:00
abstract:OBJECTIVES:We sought to describe the phenotype for patients with P.I.G. including presentation, evaluation, cardiac co-morbidities, high resolution computed tomography findings, and outcomes. METHODS:With institutional review board approval, we performed a retrospective review of patients with biopsy-proven P.I.G. Bio...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.24123
更新日期:2018-12-01 00:00:00
abstract::Pulmonary infection with Staphylococcus aureus occurs in young children with cystic fibrosis, and may contribute to the cycle of infection, inflammation, and destruction of lung tissue which leads to bronchiectasis. Practice guidelines in North America and the UK differ greatly with regard to the advice given on presc...
journal_title:Pediatric pulmonology
pub_type: 杂志文章,评审
doi:10.1002/ppul.20305
更新日期:2005-12-01 00:00:00
abstract::Our aim was to determine whether antenatal corticosteroids improve perinatal adaptation of the pulmonary circulation in lambs with lung hypoplasia (LH). LH was induced in 12 ovine fetuses between 105 and 140 days gestation (term approximately 147 days); in 6 of these the ewe was given a single dose of betamethasone (1...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20453
更新日期:2006-09-01 00:00:00
abstract::Respiration rate is an important indicator of a person's health, and thus it is monitored when performing clinical evaluations. There are different approaches for respiration monitoring, but generally they can be classed as contact or noncontact. For contact methods, the sensing device (or part of the instrument conta...
journal_title:Pediatric pulmonology
pub_type: 杂志文章,评审
doi:10.1002/ppul.21416
更新日期:2011-06-01 00:00:00
abstract::Asthma has been found related to a higher risk of psychological problems. Inconsistent results have been reported with respect to the quality of life of children with asthma. So there may be a complex relationship between asthma severity, quality of life, and psychological factors. The aim of this study was to examine...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20509
更新日期:2007-01-01 00:00:00
abstract::Phrenic nerve paralysis is a condition typically occurring after invasive procedures in the chest and neck. Here we describe a case of transient unilateral diaphragmatic paralysis in a child with status asthmaticus complicated by complete right lung atelectasis. Common causes of this disorder and possible implications...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20040
更新日期:2004-09-01 00:00:00
abstract::Our objective was to examine the characteristics of preterm and full-term infants < or = 6 weeks old that influence the success of obtaining sufficient sweat for diagnosis of CF, and corresponding sweat chloride concentrations. A retrospective chart review of 119 sweat tests was performed on 103 preterm and full-term ...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.20235
更新日期:2005-07-01 00:00:00
abstract:INTRODUCTION:We report an unusual finding of pneumatocele in an infant. CASE REPORT:A previously well four month old presented with worsening respiratory distress over 6 weeks. He had no antecedent signs or symptoms of respiratory infection. Chest radiograph demonstrated a lucent hemithorax concerning for tension pneu...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23257
更新日期:2015-12-01 00:00:00
abstract::For the last thirty years, oral chloral hydrate has been used for sedation of infants for lung function testing. Recently, however, availability of chloral hydrate became severely limited in the United States after two manufacturers discontinued manufacturing in 2012. Due to these limitations and the recent and ongoin...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23100
更新日期:2015-02-01 00:00:00
abstract:OBJECTIVES:Our therapeutic approach to a habit/tic cough is simple reassurance in a single consultation. To quality assure our practice, we followed up children to determine outcomes at least 3 months after diagnosis. DESIGN:Consecutive children diagnosed over 6 years were studied. Medical records were analyzed retros...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.23948
更新日期:2018-04-01 00:00:00
abstract::The effects of current methods of bone marrow transplantation (BMT) on pulmonary function in children have not been extensively studied. We reviewed serial pulmonary function tests (PFTs) in 25 children (median age, 9 yr; range, 4-15) who received allogeneic (n = 14) or autologous (n = 11) BMT for neoplastic diseases ...
journal_title:Pediatric pulmonology
pub_type: 杂志文章
doi:10.1002/ppul.1950180604
更新日期:1994-12-01 00:00:00