Comparison of different dosing strategies of intratracheally instilled budesonide on meconium injured piglet lungs.

abstract：:The long-term efficacy and safety of aminoglycoside aerosol therapy for Pseudomonas aeruginosa colonization/infection in cystic fibrosis has not been fully investigated. In the present study, 14 patients with cystic fibrosis, ages 8-19 years (mean: 13.3 years), received tobramycin aerosol therapy for a mean duration o...

journal_title：Pediatric pulmonology

authors： Steinkamp G,Tümmler B,Gappa M,Albus A,Potel J,Döring G,von der Hardt H

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVES:In hospitalized and nonhospitalized children with asthma exacerbations, we evaluated the determinants of (a) prolonged cough on day-14 and (b) asthma quality of life (QoL) questionnaires for parents (PACQLQ) on day-21. We hypothesized that children with more severe acute asthma are more likely to have prolon...

journal_title：Pediatric pulmonology

authors： Teoh L,Chatfield MD,Acworth JP,McCallum GB,Chang AB

更新日期：2020-11-12 00:00:00

abstract：:We report the case of a 4-year-old child with an atypical presentation of an aspirated unwitnessed foreign body in the airway. During an attempt to obtain a biopsy of what appeared to be a mucosal growth, the foreign body was removed. This may be the first report of foreign body removal in a child this young, using a ...

journal_title：Pediatric pulmonology

authors： Akhter J,Gaspar M,Bassuk A,Roberts J

更新日期：1994-07-01 00:00:00

abstract：:A continuous subcutaneous infusion of terbutaline (CSIT) was used to treat 8 children with chronic severe asthma who continued to experience frequent symptoms, despite treatment with regular oral prednisolone. Five patients experienced a symptomatic improvement from CSIT, leading to a reduction in regular medication. ...

journal_title：Pediatric pulmonology

authors： Payne DN,Balfour-Lynn IM,Biggart EA,Bush A,Rosenthal M

更新日期：2002-05-01 00:00:00

abstract：:We enrolled 30 infants (median age 3 months, range 1-12 months), hospitalized for bronchiolitis in a randomized double-blind trial, to examine the efficacy and safety of nebulized epinephrine compared to salbutamol. Once admitted, patients were treated with either nebulized 0.5 mg of an 0.1% epinephrine solution (0.5 ...

journal_title：Pediatric pulmonology

authors： Bertrand P,Araníbar H,Castro E,Sánchez I

更新日期：2001-04-01 00:00:00

abstract：:There is a subpopulation of asthmatic patients with a history of life-threatening asthma (LTA) who have a reduced perception of respiratory loads. The aim of this study was to determine if these patients have a reduced perception of both intrinsic and extrinsic loads. Children with asthma were classified into life-thr...

journal_title：Pediatric pulmonology

authors： Julius SM,Davenport KL,Davenport PW

更新日期：2002-12-01 00:00:00

abstract：:To determine whether doses of ipratropium bromide (IB) greater than those usually administered by aerosol (75-250 micrograms) give a greater degree of protection from exercise-induced asthma (EIA) in children, 12 patients with chronic asthma, ages 7-13 yr, were challenged with methacholine and exercise after inhalatio...

journal_title：Pediatric pulmonology

authors： Boner AL,Vallone G,De Stefano G

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:Decreased lung function is common in preterm-born survivors. Increased fractional exhaled nitric oxide (FeNO) appears to be a reliable test for eosinophillic airway inflammation especially in asthma. We, systematically, reviewed the literature to compare FeNO levels in preterm-born children and adults who di...

journal_title：Pediatric pulmonology

authors： Course CW,Kotecha S,Kotecha SJ

更新日期：2019-05-01 00:00:00

abstract：:This review summarizes current knowledge about the role of nitric oxide (NO) in cystic fibrosis (CF) lung disease. NO is endogenously produced by a group of enzymes, the NO synthases (NOSs). There are three isoforms of NOS, each encoded by different genes: neuronal (nNOS), immune or inducible (iNOS), and endothelial (...

journal_title：Pediatric pulmonology

authors： Grasemann H,Ratjen F

更新日期：1999-12-01 00:00:00

abstract：:The choice of antibiotics for sinusitis in children with cystic fibrosis (CF) is empirical or based on lower airway cultures, because sinus cultures are difficult to obtain. The aim of this study was to identify the main organisms cultured from CF children with chronic sinusitis, and to evaluate the concordance of con...

journal_title：Pediatric pulmonology

authors： Muhlebach MS,Miller MB,Moore C,Wedd JP,Drake AF,Leigh MW

更新日期：2006-05-01 00:00:00

abstract：:Campomelic dysplasia is a generalized disorder of cartilaginous growth and development, leading to early death from pulmonary insufficiency. We describe the airway dynamics as observed bronchoscopically in two affected infants. Both infants demonstrated anatomic compromise of the upper airway and diffuse laryngotrache...

journal_title：Pediatric pulmonology

authors： Grad R,Sammut PH,Britton JR,Goodrich P,Hoyme HE,Dambro NN

更新日期：1987-09-01 00:00:00

abstract：:SUMMARY. The detection of early airway disease in infants with cystic fibrosis (CF) may lead to earlier intervention and an improved prognosis. We hypothesized that the ratio of maximal expiratory flows while breathing a mixture of helium and oxygen (heliox) and air, referred to as density dependence (DD), would ident...

journal_title：Pediatric pulmonology

authors： Davis S,Jones M,Kisling J,Howard J,Tepper RS

更新日期：2001-01-01 00:00:00

abstract：INTRODUCTION:In cystic fibrosis (CF) patients, respiratory syncytial virus (RSV) infection is associated with significant morbidity. Although passive prophylaxis with palivizumab lowers hospitalization rate for RSV infection in populations at risk of severe infection, its use is not recommended in infants with CF disea...

journal_title：Pediatric pulmonology

authors： Giebels K,Marcotte JE,Podoba J,Rousseau C,Denis MH,Fauvel V,Laberge S

更新日期：2008-02-01 00:00:00

abstract：:Lower respiratory tract infections (LRTI) are common in the first year of life and are mostly caused by viruses. Severity of LRTI in infants is associated with early-life environmental factors. Genetic association studies also suggest a role of heredity in susceptibility to acute bronchiolitis. We designed a case cont...

journal_title：Pediatric pulmonology

authors： Goetghebuer T,Kwiatkowski D,Thomson A,Hull J

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:Percutaneous lymphatic intervention (PCL) is a promising new therapy for plastic bronchitis (PB). We characterized bronchoalveolar lavage (BAL) and cast morphology in surgically repaired congenital heart disease (CHD) patients with PB during PCL. We quantified respiratory and bronchoscopic characteristics an...

journal_title：Pediatric pulmonology

authors： Geanacopoulos AT,Savla JJ,Pogoriler J,Piccione J,Phinizy P,DeWitt AG,Blinder JJ,Pinto E,Itkin M,Dori Y,Goldfarb SB

更新日期：2018-11-01 00:00:00

abstract：:While many factors that contribute to the occurrence of lower respiratory tract infections (LRTI) in Canadian indigenous children have been described, the role of aspiration during swallowing has not been explored in these children. Because of an increase in referrals of indigenous children from our catchment area (Ma...

journal_title：Pediatric pulmonology

authors： Rempel G,Borton B,Esselmont E,Shelton C

更新日期：2011-12-01 00:00:00

abstract：:Obstructive sleep apnea syndrome (OSAS) has been associated with reduced neurocognitive performance in children, but the underlying etiology is unclear. The aim of this study was to evaluate the relationship between hypoxemia, respiratory arousals, and neurocognitive performance in snoring children referred for adenot...

journal_title：Pediatric pulmonology

authors： Kennedy JD,Blunden S,Hirte C,Parsons DW,Martin AJ,Crowe E,Williams D,Pamula Y,Lushington K

更新日期：2004-04-01 00:00:00

abstract：:To determine the role of calmodulin in postnatal lung growth and development, 4-week-old rats were injected intraperitoneally on consecutive days with trifluoperazine (TFP), a potent and specific calmodulin antagonist, for a period fo 3 weeks and studied in comparison with normal controls and undernourished weight-mat...

journal_title：Pediatric pulmonology

authors： Ofulue AF,Sekhon H,Cherukupalli K,Khadempour H,Thurlbeck WM

更新日期：1991-01-01 00:00:00

abstract：:Electronic compensation to overcome thermal artifacts during plethysmographic estimations of airway resistance is now used routinely in adults and school-age children, and was shown to be a valuable means of discriminating airway function between preschool children with and without lung disease. A similar system is no...

journal_title：Pediatric pulmonology

authors： Subbarao P,Hulskamp G,Stocks J

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Pentraxin 3 (PTX-3) is an acute-phase protein that increases in the plasma during inflammation. OBJECTIVE:We aimed to evaluate the usefulness of PTX-3 as a clinical marker in children with lower respiratory tract infection (LRTI) and examine the correlation of PTX-3 with other biomarkers such as C-reactive ...

journal_title：Pediatric pulmonology

authors： Kim HS,Won S,Lee EK,Chun YH,Yoon JS,Kim HH,Kim JT

更新日期：2016-01-01 00:00:00

abstract：:Inhalation therapy for wheezy infants with either a nebulizer or a pressurized metered-dose inhaler (pMDI) through a spacer is common practice. The aim of our study was to compare aerosol delivery to wheezy infants from a nebulizer and from a pMDI via two small volume spacers. Twenty wheezy infants (aged 4-12 months) ...

journal_title：Pediatric pulmonology

authors： Wildhaber JH,Devadason SG,Hayden MJ,Eber E,Summers QA,LeSouëf PN

更新日期：1997-03-01 00:00:00

abstract：:We evaluated 4 patients who developed severe, symptomatic stridor during maximal cardiopulmonary exercise testing, all referred due to exercise-related dyspnea. All underwent resting, unsedated transnasal fiberoptic laryngoscopy and had normal findings. Four patients performed repeat maximal exercise testing with fibe...

journal_title：Pediatric pulmonology

authors： Fahey JT,Bryant NJ,Karas D,Goldberg B,Destefano R,Gracco LC

更新日期：2005-01-01 00:00:00

abstract：OBJECTIVE:To describe and analyze the characteristics and the early risk factors for mortality of noninvasive ventilation (NIV) in critically ill children. STUDY DESIGN:A multicenter, prospective, observational 2-year study carried out with critically ill patients (1 month - 18 years of age) who needed NIV. Clinical d...

journal_title：Pediatric pulmonology

authors： López J,Pons-Òdena M,Medina A,Molinos-Norniella C,Palanca-Arias D,Demirkol D,León-González JS,López-Fernández YM,Perez-Baena L,López-Herce J,NIV Research Group.

更新日期：2020-12-31 00:00:00

abstract：OBJECTIVE:To develop and validate a questionnaire to assess asthma control in children (CAN). DESIGN:Two versions of the CAN (for carers and children) were developed. Both versions were validated in an observational, prospective, multicenter study performed in 38 hospital outpatient clinics throughout Spain. Four hund...

journal_title：Pediatric pulmonology

authors： Pérez-Yarza EG,Badía X,Badiola C,Cobos N,Garde J,Ibero M,Villa JR,CAN Investigator Group.

更新日期：2009-01-01 00:00:00

abstract：:To determine the natural history of lung vascular remodeling and cardiac changes in the rat model of persistent pulmonary hypertension syndrome (PPHN) of the newborn, we studied fetal rats subjected to maternal indomethacin administration initiated on day 19 of gestation and continued for 2, 3, or 4 days. Animals rece...

journal_title：Pediatric pulmonology

authors： Fabris VE,Pato MD,Belik J

更新日期：2001-05-01 00:00:00

abstract：:To assess whether there is a maturation of the response to tube breathing during the first 10 days of life, we have measured the dynamic ventilatory responses of nine term infants (34 studies) to added tubes equivalent to two anatomical dead spaces. Such a method allows an assessment of the baby's ability to increase ...

journal_title：Pediatric pulmonology

authors： Upton CJ,Milner AD,Stokes GM,Wilson AJ

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Children with adenoid hypertrophy (AH) have impaired respiratory system defense mechanisms, such as mucociliary clearance. We hypothesized that AH negatively affects one of the most important aspects of mucociliary clearance-ciliary beat frequency (CBF) and that adenoidectomy could potentially restore this e...

journal_title：Pediatric pulmonology

authors： Marusiakova L,Durdik P,Jesenak M,Bugova G,Kvassayova J,Oppova D,Banovcin P

更新日期：2020-03-01 00:00:00

abstract：INTRODUCTION:Advance care planning (ACP), though recommended, has not been studied in adolescents with cystic fibrosis (CF). This quality improvement project engaged adolescents with advanced CF disease in ACP and assessed patient and CF provider attitudes and preferences regarding ACP discussions and tools. MATERIALS...

journal_title：Pediatric pulmonology

authors： Kazmerski TM,Weiner DJ,Matisko J,Schachner D,Lerch W,May C,Maurer SH

更新日期：2016-12-01 00:00:00

abstract：:Bronchiolitis in infancy is a risk factor for development of asthma in the first decades of life, although the majority may be asymptomatic at school age. Respiratory symptoms are common in early life, and prediction of later asthma may be challenging. We aimed to study if simple clinical variables assessed at 2 years...

journal_title：Pediatric pulmonology

authors： Mikalsen IB,Halvorsen T,Eide GE,Øymar K

更新日期：2013-06-01 00:00:00

abstract：:Respiratory system compliance (Crs) can be used to assess lung stiffness in sick, intubated infants, avoiding the use of an esophageal balloon. Crs was assessed in a group of 15 sick, intubated infants using the occlusion and inflation techniques. The occlusion technique gave satisfactory results in 13 infants. Apneic...

journal_title：Pediatric pulmonology

authors： Heaf DP,Turner H,Stocks J,Helms P

更新日期：1987-03-01 00:00:00