Progressive lung and cardiac changes associated with pulmonary hypertension in the fetal rat.

abstract：:Antimicrobial proteins are important in lung defense and are potential therapeutic agents in chronic airways infection such as seen in cystic fibrosis (CF). In preparation for future clinical studies, we sought (1) to determine levels of three antimicrobial proteins [lactoferrin, lysozyme, and secretory leukoprotease ...

journal_title：Pediatric pulmonology

authors： Sagel SD,Sontag MK,Accurso FJ

更新日期：2009-04-01 00:00:00

abstract：:A 16-year-old female with cystic fibrosis (CF) presented with an acute respiratory exacerbation during which black flecks were observed in the spontaneously expectorated sputum. The production of this pigmented sputum was subsequently attributed to Exophiala dermatitidis hyphae. Treatment with antibiotics, corticoster...

journal_title：Pediatric pulmonology

authors： Griffard EA,Guajardo JR,Cooperstock MS,Scoville CL

更新日期：2010-05-01 00:00:00

abstract：:The prognosis for patients with acute respiratory distress syndrome (ARDS) in adults and children has improved since its formal acceptance as a clinical entity in 1967. Because acute hypoxemic respiratory failure is the hallmark of acute lung injury and ARDS, the management of oxygenation is crucial. Physicians managi...

journal_title：Pediatric pulmonology

authors： Matthews BD,Noviski N

更新日期：2001-12-01 00:00:00

abstract：:Until the year 2000, systematic cystic fibrosis (CF) neonatal screening was only performed in a few regions of France. The Brittany region began in 1989, but not the neighboring region of Loire-Atlantique. The present study compares the clinical evolution of both affected populations 10 years after screening was start...

journal_title：Pediatric pulmonology

authors： Siret D,Bretaudeau G,Branger B,Dabadie A,Dagorne M,David V,de Braekeleer M,Moisan-Petit V,Picherot G,Rault G,Storni V,Roussey M

更新日期：2003-05-01 00:00:00

abstract：:Obstructive sleep apnea syndrome (OSAS) has been associated with reduced neurocognitive performance in children, but the underlying etiology is unclear. The aim of this study was to evaluate the relationship between hypoxemia, respiratory arousals, and neurocognitive performance in snoring children referred for adenot...

journal_title：Pediatric pulmonology

authors： Kennedy JD,Blunden S,Hirte C,Parsons DW,Martin AJ,Crowe E,Williams D,Pamula Y,Lushington K

更新日期：2004-04-01 00:00:00

abstract：:The aim of our study was to examine the effect of labor and birth canal compression on the rate of clearance of lung fluid. We recruited 10 babies born by vaginal delivery and 10 born by elective cesarean section (ECS). Thoracic gas volume (TGV) was measured using total body plethysmography, and functional residual ca...

journal_title：Pediatric pulmonology

authors： Lee S,Hassan A,Ingram D,Milner AD

更新日期：1999-05-01 00:00:00

abstract：RATIONALE OF THE STUDY:Increased neonatal fraction of exhaled nitric oxide (FeNO) is associated with lung symptoms early in life, while predictors of neonatal FeNO levels are unknown. The objective of this study was to investigate perinatal and genetic predictors of FeNO in healthy at-risk neonates. METHODS:FeNO was m...

journal_title：Pediatric pulmonology

authors： Chawes BL,Bischoff AL,Kreiner-Møller E,Buchvald F,Hakonarson H,Bisgaard H

更新日期：2015-02-01 00:00:00

abstract：:To assess whether there is a maturation of the response to tube breathing during the first 10 days of life, we have measured the dynamic ventilatory responses of nine term infants (34 studies) to added tubes equivalent to two anatomical dead spaces. Such a method allows an assessment of the baby's ability to increase ...

journal_title：Pediatric pulmonology

authors： Upton CJ,Milner AD,Stokes GM,Wilson AJ

更新日期：1990-01-01 00:00:00

abstract：:The cotton rat was evaluated as a model for anti-inflammatory and antiviral influenza therapy. Beginning 3 days after intranasal infection with 10(7) tissue culture infectious doses-50% (TCID)(50) of an H3N2 human influenza, animals were treated topically via intranasal lavage with a range of doses of triamcinolone ac...

journal_title：Pediatric pulmonology

authors： Ottolini M,Blanco J,Porter D,Peterson L,Curtis S,Prince G

更新日期：2003-10-01 00:00:00

abstract：:Epidemiological data suggest that respiratory syncytial virus (RSV) infection in early life is a risk factor for later asthma. There are no prospective studies on RSV infection starting from infancy progressing through childhood into adulthood. We followed up a cohort of children, hospitalized for RSV bronchiolitis or...

journal_title：Pediatric pulmonology

authors： Korppi M,Piippo-Savolainen E,Korhonen K,Remes S

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the ...

journal_title：Pediatric pulmonology

authors： Ortiz LE,McGrath-Morrow SA,Sterni LM,Collaco JM

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:In preschool children, measurement of airway resistance using interrupter technique (Rint) is feasible to assess the degree of bronchial obstruction. Although some studies measured Rint in infancy, values of Rint and its variability in preterm infants are unknown. In this study, Rint and its variability was ...

journal_title：Pediatric pulmonology

authors： Usemann J,Demann D,Anagnostopoulou P,Korten I,Gorlanova O,Schulzke S,Frey U,Latzin P

更新日期：2017-10-01 00:00:00

abstract：:Inhaled corticosteroids are commonly used in cystic fibrosis (CF), but there are few studies evaluating their safety in young children. We, therefore, prospectively administered beclomethasone diproprionate (BDP) to 12 clinically stable young children with CF to examine the safety of this therapy with respect to adren...

journal_title：Pediatric pulmonology

authors： Wojtczak HA,Kerby GS,Wagener JS,Copenhaver SC,Gotlin RW,Riches DW,Accurso FJ

更新日期：2001-10-01 00:00:00

abstract：:The gene that encodes for the cystic fibrosis transmembrane regulator protein (CFTR) was identified in 1989, yet major pathophysiologic questions remain unanswered. There is emerging evidence that CFTR is a bicarbonate channel, a driver of chloride-bicarbonate exchange and through its action on local pH, a regulator o...

journal_title：Pediatric pulmonology

authors： Borowitz D

更新日期：2015-10-01 00:00:00

abstract：:Recurrent respiratory symptoms are common in preterm infants in the first 2 years of life. The aim of this study was to determine the lung function abnormalities associated with such symptoms. Forty preterm infants, with a median gestational age of 29 weeks were studied at a median postnatal age of 12 months. Twenty-t...

journal_title：Pediatric pulmonology

authors： Yuksel B,Greenough A

更新日期：1991-01-01 00:00:00

abstract：:Intrauterine inflammation generates inflammatory mediators that damage the developing bronchoalveolar epithelium, resulting in neonatal lung injury. Lung fluid transport disorders are the main reasons for the development of pulmonary edema, an important pathology of lung injury. Previous studies suggested that epithel...

journal_title：Pediatric pulmonology

authors： Lu K,Chen X,Zhu W,Mao X,Yang Y,Qiu J,Zhang M,Cheng R

更新日期：2019-03-01 00:00:00

abstract：:Spontaneous hemopneumothorax (SHP) is a rare potentially life-threatening condition that occurs in predominantly young adolescents. The resultant massive hemorrhage leading to hypovolemic shock can be a surgical emergency. It constitutes 1-12% of all spontaneous pneumothoraces and presents with two cardinal features, ...

journal_title：Pediatric pulmonology

authors： Chen TH,Tseng YH,Tseng CM,Chiang HH,Lin TJ

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVES:To review 15-year trends in respiratory care of extremely preterm infants managed in a tertiary perinatal center; to identify the factors contributing to their evolution; and to determine whether these changes had an impact on infant mortality, severe morbidity, and growth. METHODS:Retrospective cohort stud...

journal_title：Pediatric pulmonology

authors： Habas F,Durand S,Milési C,Mesnage R,Combes C,Gavotto A,Picaud JC,Cambonie G

更新日期：2020-08-01 00:00:00

abstract：:Our objective was to determine whether postnatal respiratory function, lung growth, and lung structure are affected by preterm birth which did not require neonatal respiratory support. Two groups of preterm (P) lambs were delivered 2 weeks before term, at 133 days of gestational age (GA). Tissue was collected at term ...

journal_title：Pediatric pulmonology

authors： Cock M,Hanna M,Sozo F,Wallace M,Yawno T,Suzuki K,Maritz G,Hooper S,Harding R

更新日期：2005-10-01 00:00:00

abstract：:Follow-up studies have demonstrated that bronchiolitis caused by respiratory syncytial virus (RSV) is strongly associated with wheezing in the ensuing years. During the acute infection the immune response may induce long-lasting detrimental effects, thereby contributing to post-bronchiolitis wheezing (PBW). Therefore,...

journal_title：Pediatric pulmonology

authors： van Woensel JB,Kimpen JL,Sprikkelman AB,Ouwehand A,van Aalderen WM

更新日期：2000-08-01 00:00:00

abstract：:A 13-year-old boy presented with a history of respiratory infection that had progressed for 3 months. A chest X-ray showed pathological findings that suggested endothoracic fascia compromise (Skarby sign). The thorax computerized axial tomography scan revealed multiple opacities in the fascia. A biopsy was performed, ...

journal_title：Pediatric pulmonology

authors： Broglia B,Bisero E,Sclavo L,Andreozzi P

更新日期：2006-05-01 00:00:00

abstract：:The incidence of necrotizing pneumonia and empyema complicated by bronchopleural fistula is rising. We describe the case of a 2-year-old boy who presented with empyema thoracis and necrotizing pneumonia who developed a bronchopleural fistula. At initial thoracotomy for decortication, necrotic lung was found and resect...

journal_title：Pediatric pulmonology

authors： Peters RT,Child F,Long AM,Humphrey GM,Rakoczy G

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:In 1995 the Tucson Children's Respiratory Study (TCRS) identified clinically distinct phenotypes amongst early wheezers; the Avon Longitudinal Study of Parents And Children (ALSPAC) has recently re-examined these. OBJECTIVES:To validate statistically derived ALSPAC phenotypes in the Southampton Women's Surv...

journal_title：Pediatric pulmonology

authors： Collins SA,Pike KC,Inskip HM,Godfrey KM,Roberts G,Holloway JW,Lucas JS,Southampton Women's Survey Study Group.

更新日期：2013-07-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Little is known about molecular changes in lungs of fetal rabbits with surgically induced diaphragmatic hernia (DH). Therefore, we examined in this model gene expressions of pivotal molecules for the developing lung. METHODS:At day 23 of gestation, DH was created in 12 fetuses from 4 does. Bot...

journal_title：Pediatric pulmonology

authors： Vuckovic A,Roubliova XI,Votino C,Naeije R,Jani JC

更新日期：2012-11-01 00:00:00

abstract：UNLABELLED:The main goal of the study was to assess possible association between transplacental exposure to genotoxic PAH compounds assessed by the cord blood PAH-DNA adducts and fractional exhaled nitric oxide (FeNO) measured in healthy non-asthmatic children at the age of 7 years. The subjects included the subsample ...

journal_title：Pediatric pulmonology

authors： Jedrychowski W,Maugeri U,Mroz E,Flak E,Rembiasz M,Jacek R,Sowa A

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Children's perception of their symptoms has proved reliable and relevant to disease management and should be considered when assessing their asthma control. The aim of the study is to validate the Brazilian Portuguese version of the Childhood Asthma Control Test (c-ACT) in children aged 4-11 years. METHODS:...

journal_title：Pediatric pulmonology

authors： Oliveira SG,Sarria EE,Roncada C,Stein RT,Pitrez PM,Mattiello R

更新日期：2016-04-01 00:00:00

abstract：:The structure, distribution, and frequency of neuroendocrine (NE) cells in human fetal lung from early stages of development to term are described. Neuroendocrine cells were studied by electron microscopy and immunostaining for serotonin and bombesin, recently identified markers of these cells in human lung. The diffe...

journal_title：Pediatric pulmonology

authors： Cutz E,Gillan JE,Bryan AC

更新日期：1985-05-01 00:00:00

abstract：:A survey of 47 cystic fibrosis referral centers was conducted to study the use of exercise in the management of patients with cystic fibrosis (CF). A questionnaire with 5 brief questions concerning the prescription and application of exercise therapy was sent to the first 47 centers (38.5%) listed in the 1988 CF Found...

journal_title：Pediatric pulmonology

authors： Kaplan TA,ZeBranek JD,McKey RM Jr

更新日期：1991-01-01 00:00:00

abstract：:We measured then compared the dynamic lung mechanics of spontaneous breaths and mechanical breaths in 9 mechanically ventilated neonates with hyaline membrane disease. All were receiving intermittent mandatory ventilation. All breathed spontaneously between ventilator breaths. Tidal volume, transpulmonary pressure, dy...

journal_title：Pediatric pulmonology

authors： Mammel MC,Fisher JB,Bing DR,Gatto CW,Boros SJ

更新日期：1990-01-01 00:00:00

abstract：:Pulmonary function and exercise tolerance were evaluated in late childhood in two groups of prematurely born children: one group with bronchopulmonary dysplasia (BPD) [n = 15; gestational age at birth (GA): 29.6 +/- 2.8 weeks; birth weight (BW): 1,367 +/- 548 g; age at test: 7.9 +/- 0.6 years], and a second group with...

journal_title：Pediatric pulmonology

authors： Parat S,Moriette G,Delaperche MF,Escourrou P,Denjean A,Gaultier C

更新日期：1995-11-01 00:00:00