Validation of the Brazilian version of the childhood asthma control test (c-ACT).

abstract：:In order to better understand the regulation of lung maturation by glucocorticoid-glucocorticoid receptor signaling, we studied glucocorticoid receptor (GR) hypomorphic mice with a mixed C57Bl6/129 sv background, in which disruption of exon 2 of the GR gene produces an N-terminal truncated GR protein. Four groups of m...

journal_title：Pediatric pulmonology

authors： Nemati B,Atmodjo W,Gagnon S,Humes D,McKerlie C,Kaplan F,Sweezey NB

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:To examine cystic fibrosis (CF) physician adherence to the 2007 CF Foundation (CFF) Pulmonary Guidelines for Chronic Medications. Specifically adherence and barriers to prescribing level A medication recommendations (i.e., inhaled tobramycin and dornase alfa) and level B medication recommendations (i.e., macr...

journal_title：Pediatric pulmonology

authors： Glauser TA,Nevins PH,Williamson JC,Abdolrasulnia M,Salinas GD,Zhang J,Debonnett L,Riekert KA

更新日期：2012-05-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Little is known about molecular changes in lungs of fetal rabbits with surgically induced diaphragmatic hernia (DH). Therefore, we examined in this model gene expressions of pivotal molecules for the developing lung. METHODS:At day 23 of gestation, DH was created in 12 fetuses from 4 does. Bot...

journal_title：Pediatric pulmonology

authors： Vuckovic A,Roubliova XI,Votino C,Naeije R,Jani JC

更新日期：2012-11-01 00:00:00

abstract：:SUMMARY. The detection of early airway disease in infants with cystic fibrosis (CF) may lead to earlier intervention and an improved prognosis. We hypothesized that the ratio of maximal expiratory flows while breathing a mixture of helium and oxygen (heliox) and air, referred to as density dependence (DD), would ident...

journal_title：Pediatric pulmonology

authors： Davis S,Jones M,Kisling J,Howard J,Tepper RS

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:In cystic fibrosis (CF), the spectrum and frequency of CFTR variants differ by geography and race/ethnicity. CFTR variants in White patients are well-described compared with Latino patients. No studies of CFTR variants have been done in patients with CF in the Dominican Republic or Puerto Rico. METHODS:CFTR...

journal_title：Pediatric pulmonology

authors： Zeiger AM,McGarry ME,Mak ACY,Medina V,Salazar S,Eng C,Liu AK,Oh SS,Nuckton TJ,Jain D,Blackwell TW,Kang HM,Abecasis G,Oñate LC,Seibold MA,Burchard EG,Rodriguez-Santana J

更新日期：2020-02-01 00:00:00

abstract：:Three adults with cystic fibrosis (one after lung transplantation) presented with fever, chest pain, and acute radiographic changes. The changes included a cavitary lesion of the lung, acute dense infiltrates, and lobar collapse. After failing conventional antibiotic therapy, the patients underwent flexible bronchosco...

journal_title：Pediatric pulmonology

authors： Colin AA,Tsiligiannis T,Nosé V,Waltz DA

更新日期：2006-02-01 00:00:00

abstract：:Phrenic nerve pacing has been used since 1966 to support breathing in quadriplegics and patients with central hypoventilation syndrome (CHS). Recently, using low-frequency, long-inspiratory-time (Ti) stimulation, phrenic nerve pacing has been used successfully to support breathing 24 hours per day in adults and older ...

journal_title：Pediatric pulmonology

authors： Brouillette RT,Ilbawi MN,Klemka-Walden L,Hunt CE

更新日期：1988-01-01 00:00:00

abstract：:Sudden unexplained deaths have been reported in 13% [corrected] of Familial Dysautonomia (FD) subjects. To characterize cardiorespiratory dysregulation in children with FD that might contribute to potential sudden death, respiratory inductance plethysmography (chest/abdomen), ECG, hemoglobin saturation, and pulse wave...

journal_title：Pediatric pulmonology

authors： Weese-Mayer DE,Kenny AS,Bennett HL,Ramirez JM,Leurgans SE

更新日期：2008-03-01 00:00:00

abstract：OBJECTIVE:To determine reference values of sniff nasal inspiratory pressure (SNIP) in healthy children. METHODS:This cross-sectional observational study included healthy children aged 6 to 11 years of both sexes. The volunteers underwent a pulmonary function test to rule out respiratory disorders. Respiratory muscle s...

journal_title：Pediatric pulmonology

authors： Marcelino AA,Fregonezi GA,Lira MGA,de Oliveira LM,Araújo PRS,Parreira VF,de Andrade AD,Resqueti V

更新日期：2020-02-01 00:00:00

abstract：:Previously, there was insufficient evidence to confirm that pneumonia in infants and children might lead to the development of pulmonary hypertension. Recently, it has been shown that acceleration time corrected for heart rate (ATc) and the ratios of right ventricular preejection period to right ventricular ejection t...

journal_title：Pediatric pulmonology

authors： Du JB,Li SZ,Wang BL,Li YA

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Although the causative pneumococcal serotypes of invasive diseases are already extensively studied, few data are available about the pneumococcal serotypes additionally isolated from broncho-alveolar lavage samples in childhood pneumonia. STUDY AIM:To identify the causative pneumococcal serotypes in culture...

journal_title：Pediatric pulmonology

authors： De Schutter I,Malfroot A,Piérard D,Lauwers S

更新日期：2006-08-01 00:00:00

abstract：:Our objective was to determine whether a simple method of maintaining positive pressure ventilation during nonbronchoscopic bronchoalveolar lavage (NB-BAL) would successfully reduce the incidence and/or severity of desaturation events. Our design was a clinical trial with historical controls. Seventy ventilated pediat...

journal_title：Pediatric pulmonology

authors： Morrow B,Futter M,Argent A

更新日期：2004-09-01 00:00:00

abstract：:We examined the effects of within-breath changes in compliance (C) upon the accuracy of measurements of compliance and resistance (R) by linear regression analysis and by Mead and Wittenberger's method. These effects were illustrated by a computer model and by lung models with linear and nonlinear pressure/volume rela...

journal_title：Pediatric pulmonology

authors： Silva Neto G,Gerhardt T,Silberberg A,Gerhardt T,Claure N,Duara S,Bancalari E

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVES:We evaluated safety and efficacy of recombinant human growth hormone (rhGH) for improving growth, lean body mass (LBM), pulmonary function, and exercise tolerance in children with cystic fibrosis (CF) and growth restriction. STUDY DESIGN:Multicenter, open-label, controlled clinical trial comparing outcomes ...

journal_title：Pediatric pulmonology

authors： Stalvey MS,Anbar RD,Konstan MW,Jacobs JR,Bakker B,Lippe B,Geller DE

更新日期：2012-03-01 00:00:00

abstract：:It has been suggested that children with asthma recover more quickly from exercise-induced bronchoconstriction than adults. On the basis of clinical observation we hypothesized that recovery rate from exercise-induced asthma (EIA) in childhood also decreases with age. In 14 children (aged 7-12 years) with a history of...

journal_title：Pediatric pulmonology

authors： Hofstra WB,Sterk PJ,Neijens HJ,Kouwenberg JM,Duiverman EJ

更新日期：1995-09-01 00:00:00

abstract：:A 16-year-old female with cystic fibrosis (CF) presented with an acute respiratory exacerbation during which black flecks were observed in the spontaneously expectorated sputum. The production of this pigmented sputum was subsequently attributed to Exophiala dermatitidis hyphae. Treatment with antibiotics, corticoster...

journal_title：Pediatric pulmonology

authors： Griffard EA,Guajardo JR,Cooperstock MS,Scoville CL

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Cystic fibrosis (CF) genotyping has garnered increased attention since the discovery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in 1989 led to the identification of over 1700 mutations on chromosome 7. Yet, little is known about the genetic profile of CF patients in Turkey. This s...

journal_title：Pediatric pulmonology

authors： Atag E,Bas Ikizoglu N,Ergenekon AP,Gokdemir Y,Eralp EE,Ata P,Ersu R,Karakoc F,Karadag B

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:A pilot study to compare pulmonary mechanics in a neonatal intensive care unit (NICU) cohort, specifically, comparing lung elastance between male and female infants in the NICU. HYPOTHESIS:Anecdotally, male infants are harder to ventilate than females. We hypothesize that males have higher model-based elast...

journal_title：Pediatric pulmonology

authors： Kim KT,Knopp J,Dixon B,Chase JG

更新日期：2020-01-01 00:00:00

abstract：:Airway obstruction in children is a rare, but difficult clinical problem, with no clear agreement on optimal therapeutic approach. Stenting of the airway has been used successfully in adults, and is an attractive alternative in children. Fundamental differences of pediatric compared to adult use include the benign nat...

journal_title：Pediatric pulmonology

authors： Nicolai T

更新日期：2008-04-01 00:00:00

abstract：:Our aim was to evaluate long-term effects of exogenous surfactant therapy on pulmonary functional outcome in children born very preterm. We examined 40 children aged 7-12 years who were born before 30 weeks of gestation with an immature surfactant system, and were randomized to one of three treatment groups: human sur...

journal_title：Pediatric pulmonology

authors： Pelkonen AS,Hakulinen AL,Turpeinen M,Hallman M

更新日期：1998-03-01 00:00:00

abstract：:Randomized trials of ribavirin therapy have used clinical scores to assess illness severity. Little information on agreement for these findings between observers has been published. We decided to determine interobserver agreement for (1) a history for apnea or respiratory failure; (2) assessment of cyanosis, respirato...

journal_title：Pediatric pulmonology

authors： Wang EE,Law BJ,Stephens D,Langley JM,MacDonald NE,Robinson JL,Dobson S,McDonald J,Boucher FD,de Carvalho V,Mitchell I

更新日期：1996-07-01 00:00:00

abstract：:A microbe-specific diagnosis in community-acquired pneumonia (CAP) is difficult in children, and studies on nonspecific chest radiographic and host response markers have been inconsistent. Serum procalcitonin (PCT) is a newly recognized, promising marker for differentiating between bacterial and viral infections. Seru...

journal_title：Pediatric pulmonology

authors： Korppi M,Remes S,Heiskanen-Kosma T

更新日期：2003-01-01 00:00:00

abstract：:Changes in the relative contribution of ribcage and abdomen during augmented breaths were assessed in two groups of infants (less than 2 weeks and 4-12 weeks old). In both groups ribcage and abdominal movements increased during augmented breaths in quiet sleep. In the older infants the relative increase was greater fo...

journal_title：Pediatric pulmonology

authors： Mathew OP,Pronske ML,Clark ML

更新日期：1988-01-01 00:00:00

abstract：:Impaired respiratory function has been found frequently in ex-premature children, but it is unclear which specific factors influence this impairment the most. The aim of this study was to determine the importance of the contributions of birth weight, gestational age, neonatal respiratory disease, and its treatment on ...

journal_title：Pediatric pulmonology

authors： Kennedy JD,Edward LJ,Bates DJ,Martin AJ,Dip SN,Haslam RR,McPhee AJ,Staugas RE,Baghurst P

更新日期：2000-07-01 00:00:00

abstract：:The assessment of apnea and asynchronous breathing requires the application of a facemask connected to a pneumotachograph and inductive transducer bands placed around the chest wall. These contact devices may alter the breathing pattern and are difficult to implement, especially in infants and children. This study val...

journal_title：Pediatric pulmonology

authors： Goldman LJ

更新日期：2012-05-01 00:00:00

abstract：OBJECTIVE:To define the mortality and long-term outcomes of children undergoing tracheostomy. DESIGN:Retrospective chart and Texas Department of Health Bureau of Vital Statistics review of patients admitted to a Pediatric Intensive Care Unit who underwent a tracheostomy between 2001 and 2011. Mortality and decannulati...

journal_title：Pediatric pulmonology

authors： McPherson ML,Shekerdemian L,Goldsworthy M,Minard CG,Nelson CS,Stein F,Graf JM

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Treatment of bronchopulmonary dysplasia (BPD) remains as yet an unmet clinical need and recently stem cells have been proposed as a therapeutic tool in animal models. We investigated the role of amniotic fluid stem cells (AFS) in an adult rat model of hyperoxia lung injury. METHODS:Fifty Sprague-Dawley rats...

journal_title：Pediatric pulmonology

authors： Grisafi D,Pozzobon M,Dedja A,Vanzo V,Tomanin R,Porzionato A,Macchi V,Salmaso R,Scarpa M,Cozzi E,Fassina A,Navaglia F,Maran C,Onisto M,Caenazzo L,De Coppi P,De Caro R,Chiandetti L,Zaramella P

更新日期：2013-11-01 00:00:00

abstract：:The prevalence and morbidity of asthma are growing problems that appear to affect urban populations and particularly impoverished centers disproportionately. Poor children are more likely to be hospitalized for asthma than nonpoor children, and are more likely to experience clinical and social dysfunction due to asthm...

journal_title：Pediatric pulmonology

authors： Shapiro GG,Stout JW

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:sTREM-1 (soluble triggering receptor expressed on myeloid cells-1) is a novel inflammatory marker that may be of clinical use in cystic fibrosis (CF). Dysregulation of the TREM pathway has been demonstrated in other inflammatory diseases and modulation in animal models has therapeutic benefit. We hypothesise...

journal_title：Pediatric pulmonology

authors： Forrester DL,Barr HL,Fogarty A,Knox A

更新日期：2017-04-01 00:00:00

abstract：BACKGROUND:Magnetic Resonance Imaging (MRI) techniques to image the larynx have evolved rapidly into a promising and safe imaging modality, without need for sedation or ionizing radiation. MRI is therefore of great interest to image pediatric laryngeal diseases. Our aim was to review MRI developments relevant for the p...

journal_title：Pediatric pulmonology

authors： Elders BBLJ,Hermelijn SM,Tiddens HAWM,Pullens B,Wielopolski PA,Ciet P

更新日期：2019-04-01 00:00:00