Effect of spontaneous and mechanical breathing on dynamic lung mechanics in hyaline membrane disease.

Abstract:

:We measured then compared the dynamic lung mechanics of spontaneous breaths and mechanical breaths in 9 mechanically ventilated neonates with hyaline membrane disease. All were receiving intermittent mandatory ventilation. All breathed spontaneously between ventilator breaths. Tidal volume, transpulmonary pressure, dynamic lung compliance, airways resistance, and peak inspiratory and peak expiratory gas flows were determined for both the mechanical and the spontaneous breaths. The mechanical breaths consistently had larger tidal volumes, higher transpulmonary pressures, higher airway resistance, and lower lung compliance values (P less than 0.05). Peak inspiratory and expiratory gas flows were also higher (P less than 0.01) during mechanical breathing. The spontaneous breaths generated by patients and the mechanical breaths generated by mechanical ventilators are different. The lung mechanics measurements of these two different types of breathing should be collected, analyzed, and reported separately.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Mammel MC,Fisher JB,Bing DR,Gatto CW,Boros SJ

doi

10.1002/ppul.1950080403

subject

Has Abstract

pub_date

1990-01-01 00:00:00

pages

222-5

issue

4

eissn

8755-6863

issn

1099-0496

journal_volume

8

pub_type

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