DENND1B gene variants associate with elevated exhaled nitric oxide in healthy high-risk neonates.

abstract：BACKGROUND:In preschool children, measurement of airway resistance using interrupter technique (Rint) is feasible to assess the degree of bronchial obstruction. Although some studies measured Rint in infancy, values of Rint and its variability in preterm infants are unknown. In this study, Rint and its variability was ...

journal_title：Pediatric pulmonology

authors： Usemann J,Demann D,Anagnostopoulou P,Korten I,Gorlanova O,Schulzke S,Frey U,Latzin P

更新日期：2017-10-01 00:00:00

abstract：:We studied the left lung using multi-focus microphotography in 378 rat fetuses, assessing airway branching from day 13 to day 19 of gestation, and lung growth variables from day 13 to day 21. Longitudinal growth, and monopodial and dichotomous branching brought about a consistent airway pattern with variations within ...

journal_title：Pediatric pulmonology

authors： Rotschild A,Massoud EA,Solimano A,Puterman ML,Sekhon HS,Thurlbeck WM

更新日期：1996-04-01 00:00:00

abstract：BACKGROUND:Asthma and obstructive sleep apnea (OSA) in children share multiple epidemiological risk factors and the prevalence of snoring is higher in asthmatic children, suggesting that the latter may be at increased risk for OSA. Since both asthma and OSA are inflammatory disorders, we hypothesized that polysomnograp...

journal_title：Pediatric pulmonology

authors： Kheirandish-Gozal L,Dayyat EA,Eid NS,Morton RL,Gozal D

更新日期：2011-09-01 00:00:00

abstract：INTRODUCTION:In this cohort study spanning an 18-year period, we evaluated the prevalence and associated mortality rate of epidemic strains of pseudomonas aeruginosa (PsA), especially Australian Epidemic Strain Type 1 (AES1), in a pediatric cystic fibrosis center practicing cohort segregation and early PsA eradication....

journal_title：Pediatric pulmonology

authors： Kevat A,Carzino R,Massie J,Harrison J,Griffiths AL

更新日期：2018-11-01 00:00:00

abstract：:This paper assesses the effectiveness of aerosolized tobramycin (TOBI) on cystic fibrosis (CF) lung disease, using a radiologic tool. The published tool, the age-based severity curve (ABS), is derived from Brasfield scoring of chest X-rays (CXR). This study evaluates both the usefulness of the ABS as an assessment too...

journal_title：Pediatric pulmonology

authors： Slattery DM,Zurakowski D,Colin AA,Cleveland RH

更新日期：2004-07-01 00:00:00

abstract：:The main purpose of this study was to evaluate four different forms of treatment in young infants admitted for acute wheezing (AW). Seventy-nine infants less than one year of age were randomly assigned to one of five groups. Group 1 received nebulized fenoterol plus ipratropium bromide, group 2 fenoterol, group 3 feno...

journal_title：Pediatric pulmonology

authors： Mallol J,Barrueto L,Girardi G,Muñoz R,Puppo H,Ulloa V,Toro O,Quevedo F

更新日期：1987-09-01 00:00:00

abstract：OBJECTIVE:To examine cystic fibrosis (CF) physician adherence to the 2007 CF Foundation (CFF) Pulmonary Guidelines for Chronic Medications. Specifically adherence and barriers to prescribing level A medication recommendations (i.e., inhaled tobramycin and dornase alfa) and level B medication recommendations (i.e., macr...

journal_title：Pediatric pulmonology

authors： Glauser TA,Nevins PH,Williamson JC,Abdolrasulnia M,Salinas GD,Zhang J,Debonnett L,Riekert KA

更新日期：2012-05-01 00:00:00

abstract：:Pulmonary sequestration is a rare anomaly and is conventionally treated with surgical excision. This report describes the successful occlusion of a large aberrant artery to an intralobar pulmonary sequestration using an Amplatzer Vascular Plug. ...

journal_title：Pediatric pulmonology

authors： Hwang HK,Tsai YS,Lin SM,Chen MR

更新日期：2008-09-01 00:00:00

abstract：:Patients with cystic fibrosis (CF) often experience acute pulmonary exacerbations (APE) and may be treated with a wide variety of intravenous antibiotics. The aim of this review is to provide an evidence-based summary of pharmacokinetic/pharmacodynamic (PK/PD), tolerability, and efficacy studies utilizing the intraven...

journal_title：Pediatric pulmonology

authors： Young DC,Zobell JT,Waters CD,Ampofo K,Stockmann C,Sherwin CM,Spigarelli MG

更新日期：2013-01-01 00:00:00

abstract：:We describe a method for measuring carbon monoxide diffusing capacity (DL(CO)) and alveolar volume (V(A)) in sleeping infants, using a single 4-sec breath-hold technique. The breath-hold maneuver is obtained by inducing a respiratory pause of the respiratory system. Several inflations of the respiratory system with ro...

journal_title：Pediatric pulmonology

authors： Castillo A,Llapur CJ,Martinez T,Kisling J,Williams-Nkomo T,Coates C,Tepper RS

更新日期：2006-06-01 00:00:00

abstract：:A 13-year-old boy presented with a history of respiratory infection that had progressed for 3 months. A chest X-ray showed pathological findings that suggested endothoracic fascia compromise (Skarby sign). The thorax computerized axial tomography scan revealed multiple opacities in the fascia. A biopsy was performed, ...

journal_title：Pediatric pulmonology

authors： Broglia B,Bisero E,Sclavo L,Andreozzi P

更新日期：2006-05-01 00:00:00

abstract：:Multiple breath inert gas washout (MBW) is gaining popularity for measurements of resting lung volume and ventilation inhomogeneity. Test reproducibility is an important determinant of the clinical applicability of diagnostic tests. The between-test reproducibility of variables derived from MBW tests in newborn infant...

journal_title：Pediatric pulmonology

authors： Sinhal S,Galati J,Baldwin DN,Stocks J,Pillow JJ

更新日期：2010-01-01 00:00:00

abstract：:The collection of sputum for microbiological examination in young cystic fibrosis patients can be very difficult. However, a knowledge of bacterial flora colonizing the patient's airways is of paramount importance for proper antimicrobial therapy. It is also known that cystic fibrosis patients colonized by Pseudomonas...

journal_title：Pediatric pulmonology

authors： Vogelberg C,Hirsch T,Rösen-Wolff A,Kerkmann ML,Leupold W

更新日期：2003-10-01 00:00:00

abstract：:The cotton rat was evaluated as a model for anti-inflammatory and antiviral influenza therapy. Beginning 3 days after intranasal infection with 10(7) tissue culture infectious doses-50% (TCID)(50) of an H3N2 human influenza, animals were treated topically via intranasal lavage with a range of doses of triamcinolone ac...

journal_title：Pediatric pulmonology

authors： Ottolini M,Blanco J,Porter D,Peterson L,Curtis S,Prince G

更新日期：2003-10-01 00:00:00

abstract：:To promote early screening of patients with suspected Primary Ciliary Dyskinesia (PCD), nasal nitric oxide (nNO) measurements during tidal breathing (TB) have been developed for children unable to ensure velum closure (VC) during breath hold or expiration against resistance. To investigate technical and practical issu...

journal_title：Pediatric pulmonology

authors： Beydon N,Chambellan A,Alberti C,de Blic J,Clément A,Escudier E,Le Bourgeois M

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Asthma is a disease with reversible bronchoconstriction; however, some patients develop fixed airflow obstruction (FAO). Previous studies have reported the incidence and risk factors of FAO in adults; however, the corresponding factors in children remain poorly understood. AIM:To evaluate the incidence and ...

journal_title：Pediatric pulmonology

authors： Sousa AW,Barros Cabral AL,Arruda Martins M,Carvalho CRF

更新日期：2020-03-01 00:00:00

abstract：:Pulmonary hemorrhage (PH) is a serious complication causing acute respiratory distress in the premature infant, and it is associated with significant mortality and morbidity. The role of inflammatory mediators in this condition is largely undefined. Serial tracheal aspirates (TA) were obtained at intervals from 65 mec...

journal_title：Pediatric pulmonology

authors： Baier RJ,Loggins J,Kruger TE

更新日期：2002-08-01 00:00:00

abstract：:The choice of antibiotics for sinusitis in children with cystic fibrosis (CF) is empirical or based on lower airway cultures, because sinus cultures are difficult to obtain. The aim of this study was to identify the main organisms cultured from CF children with chronic sinusitis, and to evaluate the concordance of con...

journal_title：Pediatric pulmonology

authors： Muhlebach MS,Miller MB,Moore C,Wedd JP,Drake AF,Leigh MW

更新日期：2006-05-01 00:00:00

abstract：:Lane-Hamilton syndrome refers to the uncommon co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co-existing non-diarrheal CD. Institution of gluten-free diet in each of the three children resulted in amelioration of th...

journal_title：Pediatric pulmonology

authors： Sethi GR,Singhal KK,Puri AS,Mantan M

更新日期：2011-03-01 00:00:00

abstract：OBJECTIVES:a: To evaluate the long-term outcome of parapneumonic effusions (PPE) in children regarding lung function and exercise tolerance, (b) to investigate the role of bronchial asthma in the outcome of PPE. METHODS:The design of the study included 51 children with PPE, at least 2 years after the initial infection...

journal_title：Pediatric pulmonology

authors： Kontouli K,Hatziagorou E,Kyrvasilis F,Roilides E,Emporiadou M,Tsanakas J

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Accelerated lung function decline in cystic fibrosis (CF) is associated with mucoid Pseudomonas aeruginosa infection. Recent data suggest that mucoid P. aeruginosa may amenable to elimination from the airway. We aim to determine whether the initiation of an aggressive antibiotic eradication regimen upon init...

journal_title：Pediatric pulmonology

authors： Troxler RB,Hoover WC,Britton LJ,Gerwin AM,Rowe SM

更新日期：2012-11-01 00:00:00

abstract：:It has been previously shown that prophylactic, intravenous dexamethasone (DEX) and intratracheal recombinant human Cu/Zn superoxide dismutase (SOD) ameliorate lung injury in newborn piglets treated with 48 hr of hyperoxia and mechanical ventilation. DEX has many pharmacologic effects, including the possible induction...

journal_title：Pediatric pulmonology

authors： Davis JM,Robbins CG,Anderson T,Sahgal N,Genen L,Tierney J,Horowitz S

更新日期：1995-08-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the utility of the Cystic Fibrosis Questionnaire-Revised (CFQ-R) with toddlers and preschool-aged children. Clinically relevant relations between health-related quality of life (HRQOL), stress, and mealtime behaviors have not been examined. It was hypothesized that p...

journal_title：Pediatric pulmonology

authors： Driscoll KA,Modi AC,Filigno SS,Brannon EE,Chamberlin LA,Stark LJ,Powers SW

更新日期：2015-06-01 00:00:00

abstract：BACKGROUND:Children's perception of their symptoms has proved reliable and relevant to disease management and should be considered when assessing their asthma control. The aim of the study is to validate the Brazilian Portuguese version of the Childhood Asthma Control Test (c-ACT) in children aged 4-11 years. METHODS:...

journal_title：Pediatric pulmonology

authors： Oliveira SG,Sarria EE,Roncada C,Stein RT,Pitrez PM,Mattiello R

更新日期：2016-04-01 00:00:00

abstract：BACKGROUND:Evidence from recent studies suggests that IRT/PAP protocols may be successfully used as a purely biochemical newborn screening (NBS) for cystic fibrosis (CF) that does not require genetic screening. However, the experience with the performance of different IRT/PAP protocols remains limited. In this study, w...

journal_title：Pediatric pulmonology

authors： Sommerburg O,Hammermann J,Lindner M,Stahl M,Muckenthaler M,Kohlmueller D,Happich M,Kulozik AE,Stopsack M,Gahr M,Hoffmann GF,Mall MA

更新日期：2015-07-01 00:00:00

abstract：:Our objective was to compare the effectiveness of maximum forced expiratory flow measured at functional residual capacity (V'maxFRC) and the ratio of flow at 75% of the forced expiratory volume to peak forced expiratory flow (FEF(75)/FEF(peak)) for detecting bronchodilator-related changes in wheezy infants. In 55 infa...

journal_title：Pediatric pulmonology

authors： Sheikh S,Castile R,Hayes J,McCoy K,Eid N

更新日期：2003-09-01 00:00:00

abstract：:Polyvinyl chloride (PVC) nasogastric feeding catheters are used clinically to measure intraesophageal pressure as an estimate of pleural pressure for calculating lung compliance in infants. The accuracy of pressure measurement of 4 French gauge (FG) catheter sizes and three brands of liquid-filled catheter manometer s...

journal_title：Pediatric pulmonology

authors： Hartford CG,Rogers GG,Turner MJ

更新日期：1997-05-01 00:00:00

abstract：:SUMMARY. Patients with idiopathic scoliosis are reported to have a restrictive pattern on pulmonary function tests. A case is presented of a teenage girl with juvenile idiopathic scoliosis who had evidence of airways obstruction in addition to restriction on pulmonary function tests (PFT). Examination of flow-volume l...

journal_title：Pediatric pulmonology

authors： Borowitz D,Armstrong D,Cerny F

更新日期：2001-01-01 00:00:00

abstract：:Bronchial responsiveness to isocapnic hyperventilation with cold air (CAH) and to inhaled methacholine (MCH) was compared in 17 children with bronchial asthma. The response to cold air was expressed as the percent drop in FEV1 from baseline at 4 min. after the challenge (delta % FEV1 CAH), and the response to methacho...

journal_title：Pediatric pulmonology

authors： de Benedictis FM,Canny GJ,MacLusky IB,Levison H

更新日期：1995-06-01 00:00:00

abstract：:Traumatic injuries to the pediatric trachea are uncommon events that require prompt diagnosis and management. When they do occur, tracheal injuries often arise in the setting of high impact trauma and are accompanied by major injuries to other organ systems. In this report, we present the diagnosis and conservative ma...

journal_title：Pediatric pulmonology

authors： Sidell DR,Wood RE,Hart CK

更新日期：2017-01-01 00:00:00