Terbutaline alleviates the lung injury in the neonatal rats exposed to endotoxin: Potential roles of epithelial sodium channels.

abstract：:Neonatal exposure to intermittent hypoxia results in altered ventilatory response to subsequent hypoxia in animal models. The effect of similar exposure in human infants is unknown. Our objective was to determine the impact of sleep disordered breathing (SDB) in early infancy on ventilatory response in infants. We rec...

journal_title：Pediatric pulmonology

authors： MacLean JE,Tan S,Fitzgerald DA,Waters KA

更新日期：2013-03-01 00:00:00

abstract：:The prevalence and morbidity of asthma are growing problems that appear to affect urban populations and particularly impoverished centers disproportionately. Poor children are more likely to be hospitalized for asthma than nonpoor children, and are more likely to experience clinical and social dysfunction due to asthm...

journal_title：Pediatric pulmonology

authors： Shapiro GG,Stout JW

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVES:Sildenafil, tezosentan, and prostacyclin reduce pulmonary vascular pressures in pulmonary hypertension, but have potential to vasodilate the systemic circulation. Nebulized vasodilators allow targeted drug delivery, high local drug concentrations, less systemic hypotension, and better matching of the lung's ...

journal_title：Pediatric pulmonology

authors： Katz SL,Adatia I,Louca E,Leung K,Humpl T,Reyes JT,Coates AL

更新日期：2006-07-01 00:00:00

abstract：:A continuous subcutaneous infusion of terbutaline (CSIT) was used to treat 8 children with chronic severe asthma who continued to experience frequent symptoms, despite treatment with regular oral prednisolone. Five patients experienced a symptomatic improvement from CSIT, leading to a reduction in regular medication. ...

journal_title：Pediatric pulmonology

authors： Payne DN,Balfour-Lynn IM,Biggart EA,Bush A,Rosenthal M

更新日期：2002-05-01 00:00:00

abstract：:The assessment of apnea and asynchronous breathing requires the application of a facemask connected to a pneumotachograph and inductive transducer bands placed around the chest wall. These contact devices may alter the breathing pattern and are difficult to implement, especially in infants and children. This study val...

journal_title：Pediatric pulmonology

authors： Goldman LJ

更新日期：2012-05-01 00:00:00

abstract：BACKGROUND:The diagnosis of community-acquired pneumonia (CAP) is based mainly on the patient's medical history and physical examination. However, in severe cases a further evaluation including chest X-ray (CXR) may be necessary. At present, lung ultrasound (LUS) is not included in the diagnostic work-up of pneumonia. ...

journal_title：Pediatric pulmonology

authors： Caiulo VA,Gargani L,Caiulo S,Fisicaro A,Moramarco F,Latini G,Picano E,Mele G

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Social and family factors may influence the probability of achieving asthma control in children. Parents' quality of life has been insufficiently explored as a predictive factor linked to the probability of achieving disease control in asthmatic children. OBJECTIVE:Determine whether the parents' quality of ...

journal_title：Pediatric pulmonology

authors： Cano-Garcinuño A,Mora-Gandarillas I,Bercedo-Sanz A,Callén-Blecua MT,Castillo-Laita JA,Casares-Alonso I,Forns-Serrallonga D,Tauler-Toro E,Alonso-Bernardo LM,García-Merino Á,Moneo-Hernández I,Cortés-Rico O,Carvajal-Urueña I,Morel

更新日期：2016-07-01 00:00:00

abstract：:Patients with cystic fibrosis (CF) can be discriminated from healthy subjects by measurement of the nasal potential difference, which has become a useful outcome measure for therapies directed toward correcting defective electrolyte transport in CF. A standard operating procedure was developed by a CF Foundation clini...

journal_title：Pediatric pulmonology

authors： Standaert TA,Boitano L,Emerson J,Milgram LJ,Konstan MW,Hunter J,Berclaz PY,Brass L,Zeitlin PL,Hammond K,Davies Z,Foy C,Noone PG,Knowles MR

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PROs) are increasingly used to evaluate the efficacy of new treatments and the progression of chronic diseases. The Cystic Fibrosis Questionnaire-Revised (CFQ-R) is a disease-specific, PRO measure of health-related quality of life (HRQOL). We evaluated associations between changes ...

journal_title：Pediatric pulmonology

authors： Sawicki GS,Rasouliyan L,McMullen AH,Wagener JS,McColley SA,Pasta DJ,Quittner AL

更新日期：2011-01-01 00:00:00

abstract：:Respiration rate is an important indicator of a person's health, and thus it is monitored when performing clinical evaluations. There are different approaches for respiration monitoring, but generally they can be classed as contact or noncontact. For contact methods, the sensing device (or part of the instrument conta...

journal_title：Pediatric pulmonology

authors： Al-Khalidi FQ,Saatchi R,Burke D,Elphick H,Tan S

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the utility of the Cystic Fibrosis Questionnaire-Revised (CFQ-R) with toddlers and preschool-aged children. Clinically relevant relations between health-related quality of life (HRQOL), stress, and mealtime behaviors have not been examined. It was hypothesized that p...

journal_title：Pediatric pulmonology

authors： Driscoll KA,Modi AC,Filigno SS,Brannon EE,Chamberlin LA,Stark LJ,Powers SW

更新日期：2015-06-01 00:00:00

abstract：:Epidemiological data suggest that respiratory syncytial virus (RSV) infection in early life is a risk factor for later asthma. There are no prospective studies on RSV infection starting from infancy progressing through childhood into adulthood. We followed up a cohort of children, hospitalized for RSV bronchiolitis or...

journal_title：Pediatric pulmonology

authors： Korppi M,Piippo-Savolainen E,Korhonen K,Remes S

更新日期：2004-08-01 00:00:00

abstract：:We developed a simple method to identify neonates at high risk of bronchopulmonary dysplasia (BPD) and determined whether early (8 hours) and late (14 days) risk assessment is equally useful. A retrospective cohort design was utilized of subjects enrolled in multi-dose surfactant trials to develop each risk identifica...

journal_title：Pediatric pulmonology

authors： Rozycki HJ,Narla L

更新日期：1996-06-01 00:00:00

abstract：:In children, pulmonary sequelae contribute to early and late morbidity after bone marrow transplantation (BMT). Between 1975-1999, we performed 152 BMTs in 138 pediatric patients with malignant and nonmalignant diseases. Allogenic bone marrow was used from 99 HLA identical siblings and from 23 other related or unrelat...

journal_title：Pediatric pulmonology

authors： Griese M,Rampf U,Hofmann D,Führer M,Reinhardt D,Bender-Götze C

更新日期：2000-11-01 00:00:00

abstract：:The incidence of necrotizing pneumonia and empyema complicated by bronchopleural fistula is rising. We describe the case of a 2-year-old boy who presented with empyema thoracis and necrotizing pneumonia who developed a bronchopleural fistula. At initial thoracotomy for decortication, necrotic lung was found and resect...

journal_title：Pediatric pulmonology

authors： Peters RT,Child F,Long AM,Humphrey GM,Rakoczy G

更新日期：2013-06-01 00:00:00

abstract：:The impulse oscillometry system (IOS) was introduced as a new technique to assess airflow obstruction in patients who are not able to perform forced breathing maneuvers, e.g., subjects with cerebral palsy or severe mental retardation, and young children. This study evaluates the sensitivity and specificity of IOS para...

journal_title：Pediatric pulmonology

authors： Vink GR,Arets HG,van der Laag J,van der Ent CK

更新日期：2003-03-01 00:00:00

abstract：:Few data are known about the effects of sleep-related breathing disorders (SRBD) on the cardiovascular system in adolescents. Forty healthy adolescents (mean age, 13.7 +/- 1.6 years) answered a questionnaire regarding symptoms of sleep-related breathing disorders (SRBD) and underwent a cardiorespiratory polygraphy and...

journal_title：Pediatric pulmonology

authors： Sánchez-Armengol A,Rodríguez-Puras MJ,Fuentes-Pradera MA,Quintana-Gallego E,Borja-Urbano G,Cayuela A,Capote F

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Acquiring sputum cultures from infants is considered challenging. We describe their yield in infants with cystic fibrosis (CF) and other chronic suppurative lung diseases (CSLDs). METHODS:Retrospective medical record review over a 4-year period, for infants aged 0-2 years with ≥2 airway bacterial cultures a...

journal_title：Pediatric pulmonology

authors： Stafler P,Zaks-Hoffer G,Scheuerman O,Ben-Zvi H,Mussaffi H,Mei-Zahav M,Steuer G,Levine H,Bar-On O,Mantin H,Prais D,Blau H

更新日期：2020-12-01 00:00:00

abstract：BACKGROUND:Cystic fibrosis (CF) genotyping has garnered increased attention since the discovery of the cystic fibrosis transmembrane conductance regulator (CFTR) gene in 1989 led to the identification of over 1700 mutations on chromosome 7. Yet, little is known about the genetic profile of CF patients in Turkey. This s...

journal_title：Pediatric pulmonology

authors： Atag E,Bas Ikizoglu N,Ergenekon AP,Gokdemir Y,Eralp EE,Ata P,Ersu R,Karakoc F,Karadag B

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVES:We evaluated safety and efficacy of recombinant human growth hormone (rhGH) for improving growth, lean body mass (LBM), pulmonary function, and exercise tolerance in children with cystic fibrosis (CF) and growth restriction. STUDY DESIGN:Multicenter, open-label, controlled clinical trial comparing outcomes ...

journal_title：Pediatric pulmonology

authors： Stalvey MS,Anbar RD,Konstan MW,Jacobs JR,Bakker B,Lippe B,Geller DE

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:Pressure rise time (PRT), also known as slope time to the peak inflating pressure can be set on some modern neonatal ventilators. On other ventilators, PRT is determined by the set circuit flow. Changing slope time can affect mean airway pressure (MAP), oxygenation, and carbon dioxide elimination. Our aim wa...

journal_title：Pediatric pulmonology

authors： Chong D,Kayser S,Szakmar E,Morley CJ,Belteki G

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Different modalities of noninvasive respiratory support have been recommended for the management of acute bronchiolitis in the pediatric intensive care unit (PICU). High-flow nasal cannula (HFNC) is among the new modalities that have been widely used in the last decade. METHODS:This is a retrospective study...

journal_title：Pediatric pulmonology

authors： Habra B,Janahi IA,Dauleh H,Chandra P,Veten A

更新日期：2020-02-01 00:00:00

abstract：:Appropriate, regular exercise is of benefit to patients with cystic fibrosis (CF). As with other segments of the population, it has been difficult to devise exercise programs to which most patients will adhere for long periods of time. In healthy children, factors that are related to positive exercise compliance inclu...

journal_title：Pediatric pulmonology

authors： Prasad SA,Cerny FJ

更新日期：2002-07-01 00:00:00

abstract：:We report on a 7-month old infant with severe respiratory distress secondary to a paratracheal bronchogenic cyst. Respiratory relief was achieved by transtracheal puncture of the cyst. Surgical removal of the cyst was performed 1 week later because of radiological evidence of reaccumulation of fluid. ...

journal_title：Pediatric pulmonology

authors： De Baets F,Van Daele S,Schelstraete P,Haerynck F,Vermassen F,Broers C

更新日期：2004-12-01 00:00:00

abstract：:Neurally adjusted ventilatory assistance (NAVA) can overcome technical difficulties with synchronizing noninvasive ventilation breaths with the patient, a modality often used in very low birthweight infants (VLBW) with apnea of prematurity (AOP). This study is a retrospective single-center investigation into whether N...

journal_title：Pediatric pulmonology

authors： Tabacaru CR,Moores RR Jr,Khoury J,Rozycki HJ

更新日期：2019-11-01 00:00:00

abstract：:The airway epithelium represents a primary site for the introduction and deposition of potentially pathogenic microorganisms into the body, through inspired air. The epithelial mucosa is an important component of the innate immune system that recognizes conserved structures in microorganisms and initiates appropriate ...

journal_title：Pediatric pulmonology

authors： Gómez MI,Prince A

更新日期：2008-01-01 00:00:00

abstract：:Respiratory input impedance (Zin) is a potentially informative test of pulmonary function in infants who are unable to perform standard tests commonly performed in children and adults Analysis of Zin in dogs using the six-element model of DuBois et al. (J Appl Physiol 8:587, 1956) provides estimates of airways resista...

journal_title：Pediatric pulmonology

authors： Jackson AC,Neff KM,Dorkin HL,Lutchen KR

更新日期：1996-12-01 00:00:00

abstract：:We determined the effects of an immediately antecedent viral lower respiratory tract infection (LRI) on the severity of clinical illness, changes in lung function and airway histamine responsiveness produced by a subsequent LRI in 9-12 week old beagle puppies inoculated with canine adenovirus 2, followed in 2 weeks by...

journal_title：Pediatric pulmonology

authors： Quan SF,Witten ML,Grad R,Ray CG,Lemen RJ

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Multiple breath washout (MBW) in infants presents a number of technical challenges. Conventional MBW is based on simultaneous measurement of flow and gas concentrations. These two signals are aligned and combined to derive expired gas volumes from which lung volumes and measures of ventilation inhomogeneity ...

journal_title：Pediatric pulmonology

authors： Shawcross A,Murray CS,Goddard N,Gupta R,Watson S,Horsley A

更新日期：2016-05-01 00:00:00

abstract：:Our objective was to study meconium-induced lung injury in isolated perfused rat lungs exposed to anoxia. Our working hypothesis was that meconium-induced lung injury is independent of preexisting hypoxia, and that hypoxia will increase severity of lung injury observed after meconium aspiration. We compared five diffe...

journal_title：Pediatric pulmonology

authors： Wisniewski WM,Zagariya AM,Pavuluri N,Srinivasan H,Shankarao S,Vidyasagar D

更新日期：2005-04-01 00:00:00