Effect of pressure rise time on ventilator parameters and gas exchange during neonatal ventilation.

abstract：BACKGROUND:Accelerated lung function decline in cystic fibrosis (CF) is associated with mucoid Pseudomonas aeruginosa infection. Recent data suggest that mucoid P. aeruginosa may amenable to elimination from the airway. We aim to determine whether the initiation of an aggressive antibiotic eradication regimen upon init...

journal_title：Pediatric pulmonology

authors： Troxler RB,Hoover WC,Britton LJ,Gerwin AM,Rowe SM

更新日期：2012-11-01 00:00:00

abstract：:It has been suggested that cystic fibrosis (CF) patients harboring multiresistant (MR) Pseudomonas aeruginosa (PA) should be seen in separate clinics. The aim of this study was to test the feasibility of this by longitudinally studying the consistency of isolates of MRPA in individuals. We analyzed all respiratory tra...

journal_title：Pediatric pulmonology

authors： Davies G,McShane D,Davies JC,Bush A

更新日期：2003-04-01 00:00:00

abstract：:The aim of the study was to evaluate the effects of inhaled steroids (IS) on the improvement of clinical asthma symptoms and on the decrease in bronchial hyperreactivity (BHR). Twenty-four children with severe asthma were given 1,000 micrograms beclomethasone dipropionate (BDP) daily and compared with ten asthmatic co...

journal_title：Pediatric pulmonology

authors： Benoist MR,Brouard JJ,Rufin P,Waernessyckle S,de Blic J,Paupe J,Scheinmann P

更新日期：1992-06-01 00:00:00

abstract：:Environmental tobacco smoke, also called passive smoking, was shown to have adverse effects on the health of children. Hydrogen peroxide (H2O2) is proposed as a sensitive marker of oxidative injury and inflammatory processes in the airways, being increased in adult active cigarette smokers. We tested whether passive s...

journal_title：Pediatric pulmonology

authors： Doniec Z,Nowak D,Tomalak W,Pisiewicz K,Kurzawa R

更新日期：2005-01-01 00:00:00

abstract：:Better growth and nutritional status is strongly associated with better pulmonary function and survival in children with CF. Behavioral intervention is an efficacious treatment approach for improving calorie intake and weight gain in children with CF; and recently has been shown to facilitate maintenance of daily ener...

journal_title：Pediatric pulmonology

authors： Opipari-Arrigan L,Powers SW,Quittner AL,Stark LJ

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To determine reference values of sniff nasal inspiratory pressure (SNIP) in healthy children. METHODS:This cross-sectional observational study included healthy children aged 6 to 11 years of both sexes. The volunteers underwent a pulmonary function test to rule out respiratory disorders. Respiratory muscle s...

journal_title：Pediatric pulmonology

authors： Marcelino AA,Fregonezi GA,Lira MGA,de Oliveira LM,Araújo PRS,Parreira VF,de Andrade AD,Resqueti V

更新日期：2020-02-01 00:00:00

abstract：:Increased numbers of eosinophils and increased concentrations of plasma proteins have been found in the airways of patients with mild asthma. We used an intact guinea pig trachea model to investigate the role of eosinophil peroxidase (EPO) in altering the function of the airway epithelial barrier. EPO in the presence ...

journal_title：Pediatric pulmonology

authors： Brottman GM,Regelmann WE,Slungaard A,Wangensteen OD

更新日期：1996-03-01 00:00:00

abstract：:We have evaluated the role of eosinophil cationic protein (ECP) concentrations in serum in predicting wheezing after bronchiolitis, during infancy and early childhood. A prospective study at a university hospital serving all pediatric patients in a defined area was designed. Serum ECP concentrations were measured in 9...

journal_title：Pediatric pulmonology

authors： Reijonen TM,Korppi M,Kuikka L,Savolainen K,Kleemola M,Mononen I,Remes K

更新日期：1997-06-01 00:00:00

abstract：OBJECTIVE:Alveolar concentration (C(A)NO) and bronchial flux (J(aw)NO) of nitric oxide (NO) characterize the contributions of peripheral and proximal airways to exhaled NO. Both parameters can be estimated using a two-compartment model if the fraction of NO in orally exhaled air (FE(NO)) is measured at multiple constan...

journal_title：Pediatric pulmonology

authors： Chládková J,Senkerík M,Havlínová Z,Krcmová I,Chládek J

更新日期：2012-11-01 00:00:00

abstract：:We studied the effect of low-protein diet (8% casein) on lung growth in rats from 3 to 7 weeks of age. Their diet was isocaloric with that of control animals fed a diet of 20% casein. The calorie intake of experimental animals was increased during the first 3 weeks of the experiment, but they increased less (about 10%...

journal_title：Pediatric pulmonology

authors： Matsui R,Thurlbeck WM,Fujita Y,Yu SY,Kida K

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:Since preventive therapies for bronchopulmonary dysplasia (BPD) are limited we treated preterm infants with azithromycin to decrease the incidence of BPD. METHODS:Infants less than 1,250 g birth weight were randomized to azithromycin or placebo within 12 hr of beginning mechanical ventilation and within 72 h...

journal_title：Pediatric pulmonology

authors： Ballard HO,Shook LA,Bernard P,Anstead MI,Kuhn R,Whitehead V,Grider D,Crawford TN,Hayes D Jr

更新日期：2011-02-01 00:00:00

abstract：AIM:To analyze breathing pattern and mechanical ventilatory constraints during incremental exercise in healthy and cystic fibrosis (CF) children. METHODS:Thirteen healthy children and 6 children with cystic fibrosis volunteered to perform an incremental test on a treadmill. Exercise tidal flow/volume loops were plotte...

journal_title：Pediatric pulmonology

authors： Borel B,Leclair E,Thevenet D,Beghin L,Gottrand F,Fabre C

更新日期：2014-03-01 00:00:00

abstract：:The value of exercise testing as an objective measure of disease severity in patients with chronic chest diseases (CCD) is becoming increasingly recognized. The aim of this study was to investigate changes in oxygen uptake (VO2) during early recovery following maximal cardiopulmonary exercise testing (CPXT) in relatio...

journal_title：Pediatric pulmonology

authors： Stevens D,Oades PJ,Armstrong N,Williams CA

更新日期：2009-05-01 00:00:00

abstract：:We assessed the ability of innovative lung function tests to detect bronchial obstruction induced by methacholine bronchial challenge. Fifty-five recurrently wheezy infants (mean age 16 +/- 5.2 months) free of respiratory symptoms underwent baseline lung function tests. Forty-two completed the methacholine challenge. ...

journal_title：Pediatric pulmonology

authors： Benoist MR,Brouard JJ,Rufin P,Delacourt C,Waernessyckle S,Scheinmann P

更新日期：1994-11-01 00:00:00

abstract：:Measurements of thoracic gas volume (TGV), airway resistance (Raw), and airway conductance (Gaw) were calculated in a group of 42 normal infants using a whole-body plethysmograph. Maximum expiratory flow at functional residual capacity was measured in a separate group of 108 normal infants. Using data obtained from th...

journal_title：Pediatric pulmonology

authors： Hampton F,Beardsmore CS,Morgan W,Williams A,Taussig L,Thompson JR

更新日期：1992-11-01 00:00:00

abstract：:Little is known about the respiratory behavior of the intercostal muscles within a neonatal and developmental context. We, therefore, examined intercostal muscle electromyographic (EMG) activity in kittens (1 month old, n = 8; 2 months old, n = 7) during eupnea and heightened respiratory drive induced by hypercapnia. ...

journal_title：Pediatric pulmonology

authors： Watchko JF,Klesh KW,O'Day TL,Guthrie RD

更新日期：1988-01-01 00:00:00

abstract：:There is no consensus about reproducibility and reliability of spirometry in young children. We evaluated forced expiratory maneuvers from 98 children aged 3 to 5 years with a variety of respiratory disorders before and after bronchodilator treatment. Forced vital capacity (FVC) and forced expiratory volume in 1 sec (...

journal_title：Pediatric pulmonology

authors： Kanengiser S,Dozor AJ

更新日期：1994-09-01 00:00:00

abstract：:During the past five decades there has been increasing interest in the potential anti-inflammatory effects of macrolide antibiotics. Low-dose macrolide therapy has dramatically increased survival in patients with diffuse panbronchiolitis, a disease with many similarities to cystic fibrosis (CF). This has led to furthe...

journal_title：Pediatric pulmonology

authors： Jaffé A,Bush A

更新日期：2001-06-01 00:00:00

abstract：:Antimicrobial proteins are important in lung defense and are potential therapeutic agents in chronic airways infection such as seen in cystic fibrosis (CF). In preparation for future clinical studies, we sought (1) to determine levels of three antimicrobial proteins [lactoferrin, lysozyme, and secretory leukoprotease ...

journal_title：Pediatric pulmonology

authors： Sagel SD,Sontag MK,Accurso FJ

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:Variation of lung function is considered to be a hallmark of asthma. Although guidelines recommend measuring it as a diagnostic tool for asthma, the usefulness of this approach has not been studied in children. AIM:To assess the usefulness of home spirometry in children with nonspecific lower respiratory tr...

journal_title：Pediatric pulmonology

authors： Brouwer AF,Visser CA,Duiverman EJ,Roorda RJ,Brand PL

更新日期：2010-04-01 00:00:00

abstract：:Spontaneous hemopneumothorax (SHP) is a rare potentially life-threatening condition that occurs in predominantly young adolescents. The resultant massive hemorrhage leading to hypovolemic shock can be a surgical emergency. It constitutes 1-12% of all spontaneous pneumothoraces and presents with two cardinal features, ...

journal_title：Pediatric pulmonology

authors： Chen TH,Tseng YH,Tseng CM,Chiang HH,Lin TJ

更新日期：2014-01-01 00:00:00

abstract：:Forced oscillatory respiratory resistance was measured in 138 healthy children aged 2- to 16-years-old using a commercial unit. Regression analysis was performed using the resistance measurements obtained at frequencies of 6 Hz and 26 Hz and averages of measurements obtained at frequencies of from 6-26 Hz, 6-10 Hz, an...

journal_title：Pediatric pulmonology

authors： Hordvik NL,König P,Morris DA,Kreutz C,Pimmel RL

更新日期：1985-05-01 00:00:00

abstract：:The goal of this research was to begin the process of evaluating acceptability of infection control (IC) recommendations to CF patients and their families, determine whether compliance with IC guidelines differs from compliance with traditional CF medical treatment with respect to the variables predictive of complianc...

journal_title：Pediatric pulmonology

authors： Masterson T,Wildman BG,Newberry B,Omlor G,Bryson E,Kukay A

更新日期：2008-05-01 00:00:00

abstract：RATIONALE:Asthma is one of the most common chronic disorders of childhood and is associated with significant healthcare utilization and costs. Comorbid psychiatric illnesses, specifically depression and anxiety, are more prevalent in patients with asthma and associated with worse asthma control, more emergency departme...

journal_title：Pediatric pulmonology

authors： Munoz FA,Benton LD,Kops SA,Kowalek KA,Seckeler MD

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Treatment regimens for patients with cystic fibrosis (CF) are time-consuming and complex, resulting in consistently low adherence rates. To date, few studies have evaluated innovative technologies to improve adherence in this population. Current infection control guidelines for patients with CF seek to minim...

journal_title：Pediatric pulmonology

authors： Marciel KK,Saiman L,Quittell LM,Dawkins K,Quittner AL

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVES:We evaluated safety and efficacy of recombinant human growth hormone (rhGH) for improving growth, lean body mass (LBM), pulmonary function, and exercise tolerance in children with cystic fibrosis (CF) and growth restriction. STUDY DESIGN:Multicenter, open-label, controlled clinical trial comparing outcomes ...

journal_title：Pediatric pulmonology

authors： Stalvey MS,Anbar RD,Konstan MW,Jacobs JR,Bakker B,Lippe B,Geller DE

更新日期：2012-03-01 00:00:00

abstract：:We conducted a survey to determine parent-reported asthma prevalence, morbidity, and healthcare utilization among 3527 children attending public schools (n = 2849) and private schools (n = 678) in San Juan, Puerto Rico. Schools were randomly selected from each of 12 geographic regions of the San Juan metropolitan area...

journal_title：Pediatric pulmonology

authors： Nazario S,Casal JR,Torres-Palacios A,Rodriguez W,Delamater AM,Applegate EB,Piedimonte G,Wanner A

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Children with adenoid hypertrophy (AH) have impaired respiratory system defense mechanisms, such as mucociliary clearance. We hypothesized that AH negatively affects one of the most important aspects of mucociliary clearance-ciliary beat frequency (CBF) and that adenoidectomy could potentially restore this e...

journal_title：Pediatric pulmonology

authors： Marusiakova L,Durdik P,Jesenak M,Bugova G,Kvassayova J,Oppova D,Banovcin P

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:The pH of exhaled breath condensate (EBC) of adolescent athletes engaged in vigorous physical activity is low compared to healthy controls; however, the ionic determinants of EBC pH and the acute effects of exercise on those determinants have not been definitively established. OBJECTIVES:This study had two ...

journal_title：Pediatric pulmonology

authors： Greenwald R,Ferdinands JM,Teague WG

更新日期：2009-08-01 00:00:00

abstract：OBJECTIVE:To define the benefits of a flexible bronchoscopy (FB) service in a Paediatric Intensive Care Unit (PICU). DESIGN:Review of the first 200 FBs undertaken in a large PICU. SETTING:Large cardiac and medical PICU in the United Kingdom, also providing extra-corporeal life support. PATIENTS:129 patients (78 male...

journal_title：Pediatric pulmonology

authors： Davidson MG,Coutts J,Bell G

更新日期：2008-12-01 00:00:00