Diagnostic value of sputum cultures in children under 2 years of age with chronic suppurative lung diseases.

abstract：:Randomized trials of ribavirin therapy have used clinical scores to assess illness severity. Little information on agreement for these findings between observers has been published. We decided to determine interobserver agreement for (1) a history for apnea or respiratory failure; (2) assessment of cyanosis, respirato...

journal_title：Pediatric pulmonology

authors： Wang EE,Law BJ,Stephens D,Langley JM,MacDonald NE,Robinson JL,Dobson S,McDonald J,Boucher FD,de Carvalho V,Mitchell I

更新日期：1996-07-01 00:00:00

abstract：:For patients whose asthma remains in poor control necessitating high utilization of medical services, a referral to a specialized "center of excellence" is often considered. A decade ago, we evaluated our pediatric asthma program of long-term hospitalization (median stay of 75 days) and found significant decreases in ...

journal_title：Pediatric pulmonology

authors： Bratton DL,Price M,Gavin L,Glenn K,Brenner M,Gelfand EW,Klinnert MD

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Decreased lung function is common in preterm-born survivors. Increased fractional exhaled nitric oxide (FeNO) appears to be a reliable test for eosinophillic airway inflammation especially in asthma. We, systematically, reviewed the literature to compare FeNO levels in preterm-born children and adults who di...

journal_title：Pediatric pulmonology

authors： Course CW,Kotecha S,Kotecha SJ

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Gastro-esophageal reflux (GOR) may contribute to lung disease in children with cystic fibrosis (CF). There is conflicting evidence regarding the effect of chest physiotherapy (CPT) in the head-down position on GOR. Furthermore, there is currently no evidence on the impact of physiotherapy on GOR as assessed ...

journal_title：Pediatric pulmonology

authors： Doumit M,Krishnan U,Jaffé A,Belessis Y

更新日期：2012-02-01 00:00:00

abstract：:The current bronchopulmonary dysplasia (BPD) is seen in infants born extremely premature, with less severe respiratory distress syndrome (RDS) and who received prenatal steroids-"new BPD". The pathophysiology of BPD is based on an impairment of lung maturation with prenatal and postnatal multi-hit insults and genetic ...

journal_title：Pediatric pulmonology

authors： Kugelman A,Durand M

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Severe inflammation plays a vital role in the pathogenesis of meconium aspiration syndrome (MAS). Intratracheal (IT) instillation of corticosteroids may be beneficial for MAS in optimizing local effect and reducing systemic adverse effects, but the optimum dosing course remains open to question. METHODS:Thi...

journal_title：Pediatric pulmonology

authors： Lin CH,Jeng MJ,Yang YC,Hsiao YH,Kou YR

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the ...

journal_title：Pediatric pulmonology

authors： Ortiz LE,McGrath-Morrow SA,Sterni LM,Collaco JM

更新日期：2017-12-01 00:00:00

abstract：:To determine whether doses of ipratropium bromide (IB) greater than those usually administered by aerosol (75-250 micrograms) give a greater degree of protection from exercise-induced asthma (EIA) in children, 12 patients with chronic asthma, ages 7-13 yr, were challenged with methacholine and exercise after inhalatio...

journal_title：Pediatric pulmonology

authors： Boner AL,Vallone G,De Stefano G

更新日期：1989-01-01 00:00:00

abstract：:Respiratory syncytial virus (RSV) lower respiratory tract infection (LRTI) during early childhood may be associated with subsequent pulmonary sequelae, including recurrent wheezing and asthma. We undertook a systematic review to investigate the pulmonary function sequelae following RSV LRTI in the first 3 years of lif...

journal_title：Pediatric pulmonology

authors： Verwey C,Nunes MC,Dangor Z,Madhi SA

更新日期：2020-07-01 00:00:00

abstract：:In order to help specialists involved in CF care and clinical research to know the current best evidence about clinical effectiveness of interventions in CF, we designed and developed a web-based, free access tool called "CFDB"--Cystic Fibrosis DataBase (www.inetflow.it/CFDB). The database was built by searching in Me...

journal_title：Pediatric pulmonology

authors： Buzzetti R,Cirilli N,Minicucci L,Raia V,Salvatore D,Maffeis P

更新日期：2014-09-01 00:00:00

abstract：:Patients with cystic fibrosis (CF) can be discriminated from healthy subjects by measurement of the nasal potential difference, which has become a useful outcome measure for therapies directed toward correcting defective electrolyte transport in CF. A standard operating procedure was developed by a CF Foundation clini...

journal_title：Pediatric pulmonology

authors： Standaert TA,Boitano L,Emerson J,Milgram LJ,Konstan MW,Hunter J,Berclaz PY,Brass L,Zeitlin PL,Hammond K,Davies Z,Foy C,Noone PG,Knowles MR

更新日期：2004-05-01 00:00:00

abstract：:In this article, we highlight cystic fibrosis (CF) research published in Pediatric Pulmonology during 2014, as well as related articles published in other journals. ...

journal_title：Pediatric pulmonology

authors： Savant AP,McColley SA

更新日期：2015-11-01 00:00:00

abstract：RATIONALE:Whether asthma constitutes a risk factor for coronavirus disease-2019 (COVID-19) is unclear. Here, we aimed to assess whether asthma, the most common chronic disease in children, is associated with higher COVID-19 risk or severity in pediatric populations. METHODS:We performed a systematic literature search ...

journal_title：Pediatric pulmonology

authors： Castro-Rodriguez JA,Forno E

更新日期：2020-09-01 00:00:00

abstract：:Fetuses of diabetic mothers who were exposed to excessive glucose show delayed maturation. Under these conditions, altered growth factor expression or signaling may have important regulatory influences. We examined the role of epidermal growth factor (EGF) in lung development and maternal diabetes in the rat. In order...

journal_title：Pediatric pulmonology

authors： Thulesen J,Poulsen SS,Nexø E,Raaberg L

更新日期：2000-02-01 00:00:00

abstract：:Ten infants with evidence of impending respiratory failure from severe bronchiolitis were successfully treated with continuous positive airway pressure (NCPAP) with double nasal prongs. Their mean (SD) age was 6.7 (3.8) months and mean (SD) body weight was 7.1 (2.1) kg. Respiratory assessments were made immediately be...

journal_title：Pediatric pulmonology

authors： Soong WJ,Hwang B,Tang RB

更新日期：1993-09-01 00:00:00

abstract：OBJECTIVE:To define the mortality and long-term outcomes of children undergoing tracheostomy. DESIGN:Retrospective chart and Texas Department of Health Bureau of Vital Statistics review of patients admitted to a Pediatric Intensive Care Unit who underwent a tracheostomy between 2001 and 2011. Mortality and decannulati...

journal_title：Pediatric pulmonology

authors： McPherson ML,Shekerdemian L,Goldsworthy M,Minard CG,Nelson CS,Stein F,Graf JM

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Although the causative pneumococcal serotypes of invasive diseases are already extensively studied, few data are available about the pneumococcal serotypes additionally isolated from broncho-alveolar lavage samples in childhood pneumonia. STUDY AIM:To identify the causative pneumococcal serotypes in culture...

journal_title：Pediatric pulmonology

authors： De Schutter I,Malfroot A,Piérard D,Lauwers S

更新日期：2006-08-01 00:00:00

abstract：:We have studied the effect of triamcinolone acetonide (TAC) on airway morphogenesis of the Sprague-Dawley fetal rat in whole organ lung cultures from day 15 to day 21 of equivalent gestational age (6 days in culture). TAC produced an increased number of peripheral buds from day 18 onward and the airway and airspaces h...

journal_title：Pediatric pulmonology

authors： Massoud EA,Sekhon HS,Rotschild A,Thurlbeck WM

更新日期：1992-09-01 00:00:00

abstract：:A variety of postnatal therapies have been and will be evaluated for prevention or treatment of neonatal chronic lung disease (CLD). A simple method for early selection of the highest risk infants would optimize intervention trials. Our study compared a clinical scoring system for predicting neonatal CLD (defined at 3...

journal_title：Pediatric pulmonology

authors： Yoder BA,Anwar MU,Clark RH

更新日期：1999-06-01 00:00:00

abstract：:Little attention has been focused on the progressive pulmonary deterioration which occurs in mechanically ventilated infants with normal or mildly abnormal lungs. We hypothesized that lung function would deteriorate over a 24-hr period in anesthetized neonatal piglets with normal lungs mechanically ventilated at 2 cm ...

journal_title：Pediatric pulmonology

authors： Easa D,Finn KC,Balaraman V,Sood S,Wilkerson S,Takenaka W,Mundie TG

更新日期：1995-03-01 00:00:00

abstract：:The jet nebulizer is a common device used for administering aerosol medication in young children. However, compared to a metered dose inhaler-spacer (MDI-spacer), it takes more time and personnel. This study aimed to compare the efficacy of salbutamol aerosol therapy given via these two devices in young wheezing child...

journal_title：Pediatric pulmonology

authors： Deerojanawong J,Manuyakorn W,Prapphal N,Harnruthakorn C,Sritippayawan S,Samransamruajkit R

更新日期：2005-05-01 00:00:00

abstract：:With better understanding of the role of type 2 inflammation in allergic asthma, there has been progress made in the development of new biologic therapies targeting these specific pathways. This review will consider diagnostic criteria for using biologic therapies for pediatric asthma with special emphasis on populati...

journal_title：Pediatric pulmonology

authors： Lovinsky-Desir S

更新日期：2020-03-01 00:00:00

abstract：:Prenatal cigarette smoke (CS) exposure, in combination with hypoxia and/or hyperthermia can lead to gasping and attenuated recovery from hypoxia in 7 days old rat pups. We studied 95 unanesthetized spontaneously breathing 14 days old rat pups to investigate if the destabilizing effects of increased ambient temperature...

journal_title：Pediatric pulmonology

authors： Pendlebury JD,Yusuf K,Bano S,Lumb KJ,Schneider JM,Hasan SU

更新日期：2012-05-01 00:00:00

abstract：:There is a need to judge general exercise tolerance in children with cystic fibrosis (CF) under normal daily activity conditions and -when more extensive testing is required-in an exercise laboratory in a specialized center. We investigated the reproducibility, validity, and criterion for a 6-minute walking test, whic...

journal_title：Pediatric pulmonology

authors： Gulmans VA,van Veldhoven NH,de Meer K,Helders PJ

更新日期：1996-08-01 00:00:00

abstract：:A microbe-specific diagnosis in community-acquired pneumonia (CAP) is difficult in children, and studies on nonspecific chest radiographic and host response markers have been inconsistent. Serum procalcitonin (PCT) is a newly recognized, promising marker for differentiating between bacterial and viral infections. Seru...

journal_title：Pediatric pulmonology

authors： Korppi M,Remes S,Heiskanen-Kosma T

更新日期：2003-01-01 00:00:00

abstract：:Some studies have suggested that lung clearance index (LCI) is age-independent among healthy subjects early in life, which implies that ventilation distribution does not vary with growth. However, other studies of older children and adolescents suggest that ventilation becomes more homogenous with somatic growth. We d...

journal_title：Pediatric pulmonology

authors： Chakr VC,Llapur CJ,Sarria EE,Mattiello R,Kisling J,Tiller C,Kimmel R,Poindexter B,Tepper RS

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:The objective of this study was to determine factors predictive of need for mechanical ventilation (MV) upon discharge from the pediatric intensive care unit (PICU) among patients who receive a tracheostomy during their stay. METHODS:This was a retrospective cohort study using the Virtual PICU Systems (VPS)...

journal_title：Pediatric pulmonology

authors： McCrory MC,Lee KJ,Scanlon MC,Wakeham MK

更新日期：2016-01-01 00:00:00

abstract：:Fetal lung hypoplasia is a common finding in several fetal conditions such as congenital diaphragmatic hernia (CDH). Interestingly, previous studies have demonstrated that hypoplastic lungs have the ability to recover to normal size, when relieved from mechanical factors. However, the underlying mechanisms remain larg...

journal_title：Pediatric pulmonology

authors： Nogueira-Silva C,Moura RS,Esteves N,Gonzaga S,Correia-Pinto J

更新日期：2008-07-01 00:00:00

abstract：:Dysfunctional swallowing is an uncommon, but important cause of bronchiectasis. We describe a child with a brainstem tumor, who developed bronchiectasis caused by chronic aspiration secondary to a dysfunctional swallow. The case highlights the importance of thorough and repeated evaluation before a diagnosis of idiopa...

journal_title：Pediatric pulmonology

authors： Bossley CJ,Hogg C,Stoneham S,Jacques TS,Bush A

更新日期：2010-02-01 00:00:00

abstract：OBJECTIVE:Since preventive therapies for bronchopulmonary dysplasia (BPD) are limited we treated preterm infants with azithromycin to decrease the incidence of BPD. METHODS:Infants less than 1,250 g birth weight were randomized to azithromycin or placebo within 12 hr of beginning mechanical ventilation and within 72 h...

journal_title：Pediatric pulmonology

authors： Ballard HO,Shook LA,Bernard P,Anstead MI,Kuhn R,Whitehead V,Grider D,Crawford TN,Hayes D Jr

更新日期：2011-02-01 00:00:00