Subcutaneous terbutaline in children with chronic severe asthma.

Abstract:

:A continuous subcutaneous infusion of terbutaline (CSIT) was used to treat 8 children with chronic severe asthma who continued to experience frequent symptoms, despite treatment with regular oral prednisolone. Five patients experienced a symptomatic improvement from CSIT, leading to a reduction in regular medication. Three patients did not experience any lasting benefit from CSIT. The most common side effects were related to the infusion site (bruising and local infection). CSIT may lead to an improvement in symptoms and a reduction in oral steroid dose in selected children with chronic severe asthma. These initial findings support the need for further controlled studies to evaluate the use of CSIT in severe childhood asthma.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Payne DN,Balfour-Lynn IM,Biggart EA,Bush A,Rosenthal M

doi

10.1002/ppul.10081

subject

Has Abstract

pub_date

2002-05-01 00:00:00

pages

356-61

issue

5

eissn

8755-6863

issn

1099-0496

pii

10.1002/ppul.10081

journal_volume

33

pub_type

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