Airway epithelial cell signaling in response to bacterial pathogens.

abstract：:Systemic onset juvenile rheumatoid arthritis is the most common rheumatologic disorder of childhood. Pleuropulmonary manifestations are rare in children in this multiorgan disease, and are usually not severe. The diagnosis of systemic onset juvenile rheumatoid arthritis is made by exclusion, in the presence of clinica...

journal_title：Pediatric pulmonology

authors： Rochat I,Sayegh Y,Gervaix A,Rimensberger PC,Argiroffo CB

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Severe inflammation plays a vital role in the pathogenesis of meconium aspiration syndrome (MAS). Intratracheal (IT) instillation of corticosteroids may be beneficial for MAS in optimizing local effect and reducing systemic adverse effects, but the optimum dosing course remains open to question. METHODS:Thi...

journal_title：Pediatric pulmonology

authors： Lin CH,Jeng MJ,Yang YC,Hsiao YH,Kou YR

更新日期：2017-07-01 00:00:00

abstract：:We measured then compared the dynamic lung mechanics of spontaneous breaths and mechanical breaths in 9 mechanically ventilated neonates with hyaline membrane disease. All were receiving intermittent mandatory ventilation. All breathed spontaneously between ventilator breaths. Tidal volume, transpulmonary pressure, dy...

journal_title：Pediatric pulmonology

authors： Mammel MC,Fisher JB,Bing DR,Gatto CW,Boros SJ

更新日期：1990-01-01 00:00:00

abstract：:The aim of our study was to determine the effects of pulmonary vascular engorgement on airways and pulmonary tissues in juvenile animals before and after methacholine (Mch)-induced changes in lung function. Five anesthetized, paralyzed, and thoracotomized piglets were studied before and during pulmonary vascular engor...

journal_title：Pediatric pulmonology

authors： Wildhaber JH,Uhlig T,Sly PD

更新日期：1998-01-01 00:00:00

abstract：:Pneumogram (PG) recordings were performed in 87 very low birthweight (VLBW) asymptomatic infants just prior to hospital discharge to determine the relationships between: 1) a prior history of apnea of prematurity (AOP) and cardiorespiratory pattern; and 2) cardiorespiratory pattern at hospital discharge and postconcep...

journal_title：Pediatric pulmonology

authors： Hageman JR,Holmes D,Suchy S,Hunt CE

更新日期：1988-01-01 00:00:00

abstract：:Eight patients with cystic fibrosis [CF] colonized with Pseudomonas aeruginosa (P. aeruginosa) had serial lung function, peripheral blood inflammatory markers, and serum IgG antibodies to Burkholderia cepacia (B. cepacia) lipopolysaccharide measured in the months preceding and following colonisation with B. cepacia. O...

journal_title：Pediatric pulmonology

authors： Hendry J,Nixon L,Dodd M,Elborn JS,Govan J,Shale DJ,Webb AK

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:'Profound intellectual and multiple disability' (PIMD) is defined as a profound cognitive disability with severe sensory and motor impairments. The aim of this study was to evaluate the respiratory morbidity in children with PIMD and investigate possible risk factors. METHODS:In 10 specialized facilities fo...

journal_title：Pediatric pulmonology

authors： Proesmans M,Vreys M,Huenaerts E,Haest E,Coremans S,Vermeulen F,Feys H

更新日期：2015-10-01 00:00:00

abstract：:Previously, there was insufficient evidence to confirm that pneumonia in infants and children might lead to the development of pulmonary hypertension. Recently, it has been shown that acceleration time corrected for heart rate (ATc) and the ratios of right ventricular preejection period to right ventricular ejection t...

journal_title：Pediatric pulmonology

authors： Du JB,Li SZ,Wang BL,Li YA

更新日期：1991-01-01 00:00:00

abstract：:The effect of viral infection on nasopharyngeal carriage of Streptococcus pneumoniae during childhood is not well known. We studied dynamics of pneumococcal colonization by quantitative PCR during the natural course of viral bronchiolitis. At time of admission, 47 (47%) of 100 patients with bronchiolitis carried pneum...

journal_title：Pediatric pulmonology

authors： Faber TE,Schuurs TA,Veeger NJ,Hennus MP,Bont LJ

更新日期：2016-08-01 00:00:00

abstract：:In 1994-1995 a cross-sectional epidemiological study investigating the respiratory health of school children in two Taiwan areas was conducted; one area was located in a region with petrochemical manufacturing complexes (Linyuan), and the other was situated in a reference area with no local industrial emissions (Taihs...

journal_title：Pediatric pulmonology

authors： Yang CY,Wang JD,Chan CC,Hwang JS,Chen PC

更新日期：1998-05-01 00:00:00

abstract：:The purpose of the study was to analyze the respiratory-dependent intraarterial blood pressure variations (pulsus paradoxus, PP) in intensive care unit patients with obstructive and restrictive pulmonary disease, and to evaluate the usefulness of PP for assessment of disease severity. One-minute paper recordings of ar...

journal_title：Pediatric pulmonology

authors： Frey B,Freezer N

更新日期：2001-02-01 00:00:00

abstract：OBJECTIVE:To examine cystic fibrosis (CF) physician adherence to the 2007 CF Foundation (CFF) Pulmonary Guidelines for Chronic Medications. Specifically adherence and barriers to prescribing level A medication recommendations (i.e., inhaled tobramycin and dornase alfa) and level B medication recommendations (i.e., macr...

journal_title：Pediatric pulmonology

authors： Glauser TA,Nevins PH,Williamson JC,Abdolrasulnia M,Salinas GD,Zhang J,Debonnett L,Riekert KA

更新日期：2012-05-01 00:00:00

abstract：:The clinical course of sarcoidosis in children has not been well defined. Eight children with symptomatic sarcoidosis included in this study underwent pulmonary function tests and bronchoscopy with bronchoalveolar lavage (BAL) before treatment and during steroid therapy. At the start of therapy, functional parameters,...

journal_title：Pediatric pulmonology

authors： Chadelat K,Baculard A,Grimfeld A,Tournier G,Boule M,Boccon-Gibod L,Clement A

更新日期：1993-07-01 00:00:00

abstract：:Cystic fibrosis (CF) is one of the most common autosomal recessive and multisystemic diseases. CF affects many systems. One of these systems is the endocrine and exocrine functions of the pancreas, causing cystic fibrosis-related diabetes, which is extremely complex and has unique pathogenesis. Maturity-onset diabetes...

journal_title：Pediatric pulmonology

authors： Hangül M,Erdoğan M,Hatipoğlu N,Köse M

更新日期：2020-05-01 00:00:00

abstract：:Cystic fibrosis (CF) patients with advanced lung disease are at risk for developing pulmonary vascular disease and pulmonary hypertension, characterized by progressive exercise intolerance beyond the exercise-limiting effects of airways disease in CF. We report on a patient with severe CF lung disease who experienced ...

journal_title：Pediatric pulmonology

authors： Montgomery GS,Sagel SD,Taylor AL,Abman SH

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:We hypothesized airway inflammation can be detected non-invasively by induced sputum (IS) or peripheral blood eosinophilia, and IS can detect bacterial and viral infection in preschool children with airway disease, with results comparable to broncho-alveolar lavage (BAL). METHODS:Preschool children with cys...

journal_title：Pediatric pulmonology

authors： Jochmann A,Artusio L,Robson K,Nagakumar P,Collins N,Fleming L,Bush A,Saglani S

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Our objective was to determine those characteristics associated with reversibility of airflow obstruction and response to maximal bronchodilation in children with severe asthma through the Severe Asthma Research Program (SARP). METHODS:We performed a cross-sectional analysis evaluating children ages 6 to 17...

journal_title：Pediatric pulmonology

authors： Coverstone AM,Bacharier LB,Wilson BS,Fitzpatrick AM,Teague WG,Phipatanakul W,Wenzel SE,Gaston BM,Bleecker ER,Moore WC,Ramratnam S,Jarjour NN,Ly NP,Fahy JV,Mauger DT,Schechtman KB,Yin-DeClue H,Boomer JS,Castro M

更新日期：2019-11-01 00:00:00

abstract：:The purpose of this study was to compare the pathogens obtained by oropharyngeal suction (OPS) and bronchoalveolar lavage (BAL) in children with chronic pulmonary infections. Forty-four children (mean age of 6.1 years; range 4 months to 15 years) were included in the study (27 children with recurrent localized lung in...

journal_title：Pediatric pulmonology

authors： Avital A,Uwyyed K,Picard E,Godfrey S,Springer C

更新日期：1995-07-01 00:00:00

abstract：INTRODUCTION:Lung disease in cystic fibrosis (CF) begins early in life but the capabilities for detecting abnormalities of pulmonary dysfunction in children remain limited. OBJECTIVE:The study aimed to evaluate the early progression of lung function by the analysis of pulmonary hyperinflation, ventilation inhomogeneit...

journal_title：Pediatric pulmonology

authors： Walicka-Serzysko K,Postek M,Milczewska J,Sands D

更新日期：2020-11-01 00:00:00

abstract：:Corticosteroids continue to be used by many physicians to treat infants with bronchiolitis. The aim of this study was to examine the short-term and long-term efficacy of oral corticosteroid therapy when added to beta2-agonists in infants with mild to moderate bronchiolitis (defined as the first episode of wheezing ass...

journal_title：Pediatric pulmonology

authors： Berger I,Argaman Z,Schwartz SB,Segal E,Kiderman A,Branski D,Kerem E

更新日期：1998-09-01 00:00:00

abstract：BACKGROUND:Consolidation on chest radiography is widely used as the reference standard for defining pneumonia and variability in interpretation is well known but not well explored or explained. METHODS:Three pediatric sub-specialists (infectious diseases, radiology and respiratory medicine) viewed 3,033 chest radiogra...

journal_title：Pediatric pulmonology

authors： Williams GJ,Macaskill P,Kerr M,Fitzgerald DA,Isaacs D,Codarini M,McCaskill M,Prelog K,Craig JC

更新日期：2013-12-01 00:00:00

abstract：:Our objective was to study meconium-induced lung injury in isolated perfused rat lungs exposed to anoxia. Our working hypothesis was that meconium-induced lung injury is independent of preexisting hypoxia, and that hypoxia will increase severity of lung injury observed after meconium aspiration. We compared five diffe...

journal_title：Pediatric pulmonology

authors： Wisniewski WM,Zagariya AM,Pavuluri N,Srinivasan H,Shankarao S,Vidyasagar D

更新日期：2005-04-01 00:00:00

abstract：:Respiratory system compliance (Crs) can be used to assess lung stiffness in sick, intubated infants, avoiding the use of an esophageal balloon. Crs was assessed in a group of 15 sick, intubated infants using the occlusion and inflation techniques. The occlusion technique gave satisfactory results in 13 infants. Apneic...

journal_title：Pediatric pulmonology

authors： Heaf DP,Turner H,Stocks J,Helms P

更新日期：1987-03-01 00:00:00

abstract：:Five children with positive serology for human immunodeficiency virus (HIV) infection by enzyme-linked immunosorbent assay and Western blot were followed for chronic pulmonary disease. Lung biopsies were performed in all patients, and confirmed the diagnosis of pulmonary lymphoid hyperplasia. All children demonstrated...

journal_title：Pediatric pulmonology

authors： Rubinstein A,Bernstein LJ,Charytan M,Krieger BZ,Ziprkowski M

更新日期：1988-01-01 00:00:00

abstract：:We recently reported that prenatal glucocorticoid therapy is less effective at promoting an improvement in lung function in male than in female sheep. This observation, and the higher incidence of respiratory distress syndrome in human males, suggests that the male fetal lung may be less responsive to glucocorticoids ...

journal_title：Pediatric pulmonology

authors： Kovar J,Waddell BJ,Sly PD,Willet KE

更新日期：2001-07-01 00:00:00

abstract：:The reliability and predictive value of salivary theophylline levels was investigated in 58 children who were treated with oral sustained-release theophylline preparations for bronchial asthma. Serum and saliva levels were assessed by fluorescence polarization immunoassay (FPIA), and Seralyzer (reagent strip reflectan...

journal_title：Pediatric pulmonology

authors： Schulte T,Buhr W,Schmidt M,Walkenbach A,Berdel D

更新日期：1989-01-01 00:00:00

abstract：:We present a child with interstitial lung disease (ILD) who was diagnosed with desquamative interstitial pneumonitis following CT thorax and open lung biopsy aged 2 years. Subsequently, surfactant protein gene analysis revealed mutations in the ABCA3 gene. This case of ABCA3 deficient ILD describes a stable clinical c...

journal_title：Pediatric pulmonology

authors： Williamson M,Wallis C

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:While the impact of fertility treatments on the perinatal outcome is well established, the long-term effects on offspring are yet to be determined. The current study aimed to investigate the risk of long-term obstructive sleep apnea (OSA) among children born following in vitro fertilization (IVF) and ovulatio...

journal_title：Pediatric pulmonology

authors： Imterat M,Wainstock T,Sheiner E,Landau D,Walfisch A,Harlev A

更新日期：2019-10-01 00:00:00

abstract：:The efficacy and tolerability of high-dose salmeterol (100 mcg, BID) and albuterol (2.5 mg, BID) were compared with those of albuterol (2.5 mg, BID) in outpatients with cystic fibrosis in a randomized, double-blind, double-dummy, placebo-controlled, crossover study with both short- (4 weeks of each) and long-term (24 ...

journal_title：Pediatric pulmonology

authors： Hordvik NL,Sammut PH,Judy CG,Colombo JL

更新日期：2002-10-01 00:00:00

abstract：:A thorough understanding of the early natural history of cystic fibrosis (CF) lung disease is critical for the development of effective interventions in the youngest patients. We assessed the evolution of pulmonary infection, inflammation, and clinical course among 40 infants over a 2-year period through annual bronch...

journal_title：Pediatric pulmonology

authors： Rosenfeld M,Gibson RL,McNamara S,Emerson J,Burns JL,Castile R,Hiatt P,McCoy K,Wilson CB,Inglis A,Smith A,Martin TR,Ramsey BW

更新日期：2001-11-01 00:00:00