Aerosol delivery to wheezy infants: a comparison between a nebulizer and two small volume spacers.

abstract：:Pulmonary hemorrhage (PH) is a serious complication causing acute respiratory distress in the premature infant, and it is associated with significant mortality and morbidity. The role of inflammatory mediators in this condition is largely undefined. Serial tracheal aspirates (TA) were obtained at intervals from 65 mec...

journal_title：Pediatric pulmonology

authors： Baier RJ,Loggins J,Kruger TE

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Severe inflammation plays a vital role in the pathogenesis of meconium aspiration syndrome (MAS). Intratracheal (IT) instillation of corticosteroids may be beneficial for MAS in optimizing local effect and reducing systemic adverse effects, but the optimum dosing course remains open to question. METHODS:Thi...

journal_title：Pediatric pulmonology

authors： Lin CH,Jeng MJ,Yang YC,Hsiao YH,Kou YR

更新日期：2017-07-01 00:00:00

abstract：:C-reactive protein (CRP) concentrations were evaluated in 9 cystic fibrosis (CF) patients with acute pulmonary exacerbations and 14 patients with acute exacerbations of asthma without any symptoms of an acute infection. CRP concentrations were serially evaluated over the course of therapy in CF patients and compared w...

journal_title：Pediatric pulmonology

authors： Friesen CA,Wiens LA,Burry VF,Portnoy J,Roberts CC

更新日期：1995-10-01 00:00:00

abstract：:Fetuses of diabetic mothers who were exposed to excessive glucose show delayed maturation. Under these conditions, altered growth factor expression or signaling may have important regulatory influences. We examined the role of epidermal growth factor (EGF) in lung development and maternal diabetes in the rat. In order...

journal_title：Pediatric pulmonology

authors： Thulesen J,Poulsen SS,Nexø E,Raaberg L

更新日期：2000-02-01 00:00:00

abstract：:SUMMARY. The detection of early airway disease in infants with cystic fibrosis (CF) may lead to earlier intervention and an improved prognosis. We hypothesized that the ratio of maximal expiratory flows while breathing a mixture of helium and oxygen (heliox) and air, referred to as density dependence (DD), would ident...

journal_title：Pediatric pulmonology

authors： Davis S,Jones M,Kisling J,Howard J,Tepper RS

更新日期：2001-01-01 00:00:00

abstract：:New Zealand children's morbidity from respiratory disease is high. This study examines whether subclinical ciliary abnormalities underlie the increased prevalence of respiratory disease in indigenous New Zealand children. A prospective study enrolled a group of healthy children who were screened for respiratory diseas...

journal_title：Pediatric pulmonology

authors： Edwards EA,Douglas C,Broome S,Kolbe J,Jensen CG,Dewar A,Bush A,Byrnes CA

更新日期：2005-03-01 00:00:00

abstract：:In 377 children, the commercially available Siregnost FD-5 was used to measure respiratory system resistance (Rrs) by forced oscillation at 10 Hz. The children were between 3 and 18 years of age and, by a detailed questionnaire and conventional pulmonary function testing in 335, they were shown to be representative of...

journal_title：Pediatric pulmonology

authors： Lebecque P,Desmond K,Swartebroeckx Y,Dubois P,Lulling J,Coates A

更新日期：1991-01-01 00:00:00

abstract：:In cystic fibrosis the bronchiectatic conducting airways have large numbers of neutrophils in their walls and in their luminal contents. The neutrophil's primary granule enzyme activities of elastase and peroxidase are increased in the sputum of these patients. It has been postulated that these enzymes--together or in...

journal_title：Pediatric pulmonology

authors： Regelmann WE,Schneider LA,Fahrenkrug SC,Gray BH,Johnson S,Herron JM,Clawson CC,Clawson DJ,Wangensteen OD

更新日期：1997-07-01 00:00:00

abstract：:Respiratory system compliance (Crs) can be used to assess lung stiffness in sick, intubated infants, avoiding the use of an esophageal balloon. Crs was assessed in a group of 15 sick, intubated infants using the occlusion and inflation techniques. The occlusion technique gave satisfactory results in 13 infants. Apneic...

journal_title：Pediatric pulmonology

authors： Heaf DP,Turner H,Stocks J,Helms P

更新日期：1987-03-01 00:00:00

abstract：OBJECTIVES:Childhood interstitial lung disease (chILD) is a group of rare chronic and complex disorders of variable pathology. There has been no systematic review of published chILD research. This study aimed to describe chILD classification systems, epidemiology, morbidity, treatments, outcomes, and the impact of chIL...

journal_title：Pediatric pulmonology

authors： Hime NJ,Zurynski Y,Fitzgerald D,Selvadurai H,Phu A,Deverell M,Elliott EJ,Jaffe A

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND:Accelerated lung function decline in cystic fibrosis (CF) is associated with mucoid Pseudomonas aeruginosa infection. Recent data suggest that mucoid P. aeruginosa may amenable to elimination from the airway. We aim to determine whether the initiation of an aggressive antibiotic eradication regimen upon init...

journal_title：Pediatric pulmonology

authors： Troxler RB,Hoover WC,Britton LJ,Gerwin AM,Rowe SM

更新日期：2012-11-01 00:00:00

abstract：:With dual energy X-ray absorptiometry (DEXA), it is possible to quantitate important aspects of growth in children with cystic fibrosis (CF), supplementing the usual measures of height and weight. Of particular concern during growth is the accumulation of bone mineral, since osteoporosis and fractures are well-recogni...

journal_title：Pediatric pulmonology

authors： Henderson RC,Madsen CD

更新日期：1999-02-01 00:00:00

abstract：:Increased numbers of eosinophils and increased concentrations of plasma proteins have been found in the airways of patients with mild asthma. We used an intact guinea pig trachea model to investigate the role of eosinophil peroxidase (EPO) in altering the function of the airway epithelial barrier. EPO in the presence ...

journal_title：Pediatric pulmonology

authors： Brottman GM,Regelmann WE,Slungaard A,Wangensteen OD

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVES:First, create a clinical severity score for patients with chronic lung disease of infancy (CLDi) following neonatal intensive care unit (NICU) stay. Second, using California wide population-based data, identify factors associated with clinical severity of CLDi at 4-9 months corrected gestational age (CGA). ...

journal_title：Pediatric pulmonology

authors： Gage S,Kan P,Oehlert J,Gould JB,Stevenson DK,Shaw GM,O'Brodovich HM

更新日期：2015-09-01 00:00:00

abstract：:A 13-year-old boy presented with a history of respiratory infection that had progressed for 3 months. A chest X-ray showed pathological findings that suggested endothoracic fascia compromise (Skarby sign). The thorax computerized axial tomography scan revealed multiple opacities in the fascia. A biopsy was performed, ...

journal_title：Pediatric pulmonology

authors： Broglia B,Bisero E,Sclavo L,Andreozzi P

更新日期：2006-05-01 00:00:00

abstract：OBJECTIVES:High incidence of genetic alterations at the microsatellite (MS) DNA level has been reported in asthmatic adults. WORKING HYPOTHESIS:The aim of this study was to investigate whether microsatellite instability (MSI) and loss of heterozygosity (LOH) were detectable phenomena in children with asthma. METHODOL...

journal_title：Pediatric pulmonology

authors： Thomou C,Paraskakis E,Neofytou E,Kalmanti M,Siafakas NM,Tzortzaki EG

更新日期：2009-10-01 00:00:00

abstract：BACKGROUND:Population-based studies investigating health-related quality of life (HRQoL) among asthmatic adolescents are rare. Further, among subjects with asthma, HRQoL may be affected by asthma control and severity. AIM:To investigate HRQoL in relation to asthma control and asthma severity among adolescents. METHOD...

journal_title：Pediatric pulmonology

authors： Stridsman C,Backman H,Eklund BM,Rönmark E,Hedman L

更新日期：2017-07-01 00:00:00

abstract：:The value of exercise testing as an objective measure of disease severity in patients with chronic chest diseases (CCD) is becoming increasingly recognized. The aim of this study was to investigate changes in oxygen uptake (VO2) during early recovery following maximal cardiopulmonary exercise testing (CPXT) in relatio...

journal_title：Pediatric pulmonology

authors： Stevens D,Oades PJ,Armstrong N,Williams CA

更新日期：2009-05-01 00:00:00

abstract：OBJECTIVE:To define the benefits of a flexible bronchoscopy (FB) service in a Paediatric Intensive Care Unit (PICU). DESIGN:Review of the first 200 FBs undertaken in a large PICU. SETTING:Large cardiac and medical PICU in the United Kingdom, also providing extra-corporeal life support. PATIENTS:129 patients (78 male...

journal_title：Pediatric pulmonology

authors： Davidson MG,Coutts J,Bell G

更新日期：2008-12-01 00:00:00

abstract：INTRODUCTION:Chest impedance (CI) is the current standard for cardio-respiratory monitoring in preterm infants but fails to provide direct and quantitative information on diaphragmatic activity. Transcutaneous electromyography (dEMG) is able to measure diaphragmatic activity, but its feasibility and repeatability to mo...

journal_title：Pediatric pulmonology

authors： Kraaijenga JV,Hutten GJ,de Jongh FH,van Kaam AH

更新日期：2015-09-01 00:00:00

abstract：UNLABELLED:Very low birth weight (VLBW) infants, even those without bronchopulmonary dysplasia (BPD) are at risk for pulmonary morbidity during infancy. Although some studies have found an association between the level of neonatal oxygen exposure and later morbidity, others have not. A possible explanation for these in...

journal_title：Pediatric pulmonology

authors： Stevens TP,Dylag A,Panthagani I,Pryhuber G,Halterman J

更新日期：2010-04-01 00:00:00

abstract：:Systemic onset juvenile rheumatoid arthritis is the most common rheumatologic disorder of childhood. Pleuropulmonary manifestations are rare in children in this multiorgan disease, and are usually not severe. The diagnosis of systemic onset juvenile rheumatoid arthritis is made by exclusion, in the presence of clinica...

journal_title：Pediatric pulmonology

authors： Rochat I,Sayegh Y,Gervaix A,Rimensberger PC,Argiroffo CB

更新日期：2004-12-01 00:00:00

abstract：:Fetal lung hypoplasia is a common finding in several fetal conditions such as congenital diaphragmatic hernia (CDH). Interestingly, previous studies have demonstrated that hypoplastic lungs have the ability to recover to normal size, when relieved from mechanical factors. However, the underlying mechanisms remain larg...

journal_title：Pediatric pulmonology

authors： Nogueira-Silva C,Moura RS,Esteves N,Gonzaga S,Correia-Pinto J

更新日期：2008-07-01 00:00:00

abstract：OBJECTIVE:To describe and analyze the characteristics and the early risk factors for mortality of noninvasive ventilation (NIV) in critically ill children. STUDY DESIGN:A multicenter, prospective, observational 2-year study carried out with critically ill patients (1 month - 18 years of age) who needed NIV. Clinical d...

journal_title：Pediatric pulmonology

authors： López J,Pons-Òdena M,Medina A,Molinos-Norniella C,Palanca-Arias D,Demirkol D,León-González JS,López-Fernández YM,Perez-Baena L,López-Herce J,NIV Research Group.

更新日期：2020-12-31 00:00:00

abstract：:Our objective was to determine the repeatability of bronchial responsiveness to mannitol dry powder (MDP) as an objective marker of asthma in children. MDP challenge was performed in children with stable asthma at the same time of the day on two separate occasions within a week. The test was terminated after a 15% fal...

journal_title：Pediatric pulmonology

authors： Barben J,Roberts M,Chew N,Carlin JB,Robertson CF

更新日期：2003-12-01 00:00:00

abstract：OBJECTIVE:To determine the effect of changing electrode positions on vital signs and respiratory effort parameters measured with transcutaneous electromyography of the diaphragm (dEMG) in preterm infants. METHODS:In this observational study, simultaneous dEMG measurements were performed at the standard position and at...

journal_title：Pediatric pulmonology

authors： van Leuteren RW,Bekhuis RE,de Waal CG,de Jongh FH,van Kaam AH,Hutten GJ

更新日期：2020-02-01 00:00:00

abstract：:Severe bronchopulmonary dysplasia (BPD) is frequently associated with asthma. The combination is often severe enough to necessitate corticosteroid therapy. There are no commercially available nebulizer solutions of corticosteroids for use in infants and young children. Seven infants and small children with very severe...

journal_title：Pediatric pulmonology

authors： König P,Shatley M,Levine C,Mawhinney TP

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:Gastro-esophageal reflux (GOR) may contribute to lung disease in children with cystic fibrosis (CF). There is conflicting evidence regarding the effect of chest physiotherapy (CPT) in the head-down position on GOR. Furthermore, there is currently no evidence on the impact of physiotherapy on GOR as assessed ...

journal_title：Pediatric pulmonology

authors： Doumit M,Krishnan U,Jaffé A,Belessis Y

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVE:Telomere length is associated with poorer lung health in older adults, possibly from cumulative risk factor exposure, but data are lacking in pediatric and population-based cohorts. We examined associations of telomere length with lung function in children and mid-life adults. METHODS:Data were drawn from a ...

journal_title：Pediatric pulmonology

authors： Nguyen MT,Saffery R,Burgner D,Lycett K,Vryer R,Grobler A,Dwyer T,Ranganathan S,Wake M

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Several studies have shown that exposure to air pollutants affects lung growth and development and can result in poor respiratory health in early life. METHODS:We included a subsample of 772 Mexican preschoolers whose mothers participated in a Prenatal Omega-3 fatty acid Supplements, GRowth, And Development...

journal_title：Pediatric pulmonology

authors： Gutiérrez-Delgado RI,Barraza-Villarreal A,Escamilla-Núñez MC,Hernández-Cadena L,Cortez-Lugo M,Sly P,Romieu I

更新日期：2020-08-01 00:00:00