Bronchial provocation testing with dry powder mannitol in children with cystic fibrosis.

abstract：BACKGROUND:Pentraxin 3 (PTX-3) is an acute-phase protein that increases in the plasma during inflammation. OBJECTIVE:We aimed to evaluate the usefulness of PTX-3 as a clinical marker in children with lower respiratory tract infection (LRTI) and examine the correlation of PTX-3 with other biomarkers such as C-reactive ...

journal_title：Pediatric pulmonology

authors： Kim HS,Won S,Lee EK,Chun YH,Yoon JS,Kim HH,Kim JT

更新日期：2016-01-01 00:00:00

abstract：:Five children with positive serology for human immunodeficiency virus (HIV) infection by enzyme-linked immunosorbent assay and Western blot were followed for chronic pulmonary disease. Lung biopsies were performed in all patients, and confirmed the diagnosis of pulmonary lymphoid hyperplasia. All children demonstrated...

journal_title：Pediatric pulmonology

authors： Rubinstein A,Bernstein LJ,Charytan M,Krieger BZ,Ziprkowski M

更新日期：1988-01-01 00:00:00

abstract：:This study evaluates different ventilator strategies during gas (GV) and partial liquid ventilation (PLV) in spontaneously breathing animals. We hypothesized that during PLV, spontaneously breathing animals would self-regulate respiratory parameters by increasing respiratory rate (RR) and minute ventilation (V'E) when...

journal_title：Pediatric pulmonology

authors： Bendel-Stenzel EM,Mrozek JD,Bing DR,Meyers PA,Connett JE,Mammel MC

更新日期：1998-11-01 00:00:00

abstract：:Angiogenesis is an important mechanism of airway remodeling in lung disease. We previously demonstrated that serum vascular endothelial growth factor (VEGF) is elevated in cystic fibrosis (CF) patients and declines with therapy for pulmonary exacerbation. We hypothesized that VEGF is elevated early in the course of CF...

journal_title：Pediatric pulmonology

authors： Watts KD,McColley SA

更新日期：2011-07-01 00:00:00

abstract：:A computerized method for the measurement of alveolar ventilation (VA) and the mean alveolar partial pressures of CO2 and O2 is described and tested in healthy, awake fullterm (FT) newborns and preterm (PT) infants (postnatal age 40 days). This study emphasizes the technical pitfalls generally encountered when dealing...

journal_title：Pediatric pulmonology

authors： Lagneaux D,Mossay C,Geubelle F,Christiaens G

更新日期：1988-01-01 00:00:00

abstract：:Campomelic dysplasia is a generalized disorder of cartilaginous growth and development, leading to early death from pulmonary insufficiency. We describe the airway dynamics as observed bronchoscopically in two affected infants. Both infants demonstrated anatomic compromise of the upper airway and diffuse laryngotrache...

journal_title：Pediatric pulmonology

authors： Grad R,Sammut PH,Britton JR,Goodrich P,Hoyme HE,Dambro NN

更新日期：1987-09-01 00:00:00

abstract：:Three adults with cystic fibrosis (one after lung transplantation) presented with fever, chest pain, and acute radiographic changes. The changes included a cavitary lesion of the lung, acute dense infiltrates, and lobar collapse. After failing conventional antibiotic therapy, the patients underwent flexible bronchosco...

journal_title：Pediatric pulmonology

authors： Colin AA,Tsiligiannis T,Nosé V,Waltz DA

更新日期：2006-02-01 00:00:00

abstract：:A 16-year-old female with cystic fibrosis (CF) presented with an acute respiratory exacerbation during which black flecks were observed in the spontaneously expectorated sputum. The production of this pigmented sputum was subsequently attributed to Exophiala dermatitidis hyphae. Treatment with antibiotics, corticoster...

journal_title：Pediatric pulmonology

authors： Griffard EA,Guajardo JR,Cooperstock MS,Scoville CL

更新日期：2010-05-01 00:00:00

abstract：:Our study was aimed at elucidating the effect of strenuous maternal exercise (running at a speed of 20 m/min) on fetal somatic growth and lung development. Dams were separated into three groups: (1) exercising during the entire course of pregnancy; (2) exercising from the 16th to the 20th gestational day; and (3) cont...

journal_title：Pediatric pulmonology

authors： Nagai A,Sakamoto K,Konno K

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Asthma is a disease with reversible bronchoconstriction; however, some patients develop fixed airflow obstruction (FAO). Previous studies have reported the incidence and risk factors of FAO in adults; however, the corresponding factors in children remain poorly understood. AIM:To evaluate the incidence and ...

journal_title：Pediatric pulmonology

authors： Sousa AW,Barros Cabral AL,Arruda Martins M,Carvalho CRF

更新日期：2020-03-01 00:00:00

abstract：:The aim of this study was to validate our Dalhousie Dyspnea Scales in children referred for histamine bronchoprovocation challenge. Seventy-four children rated their dyspnea after each FEV(1) measurement following inhalation of doubling histamine concentrations from 0.125 to 8.0 mg/ml by the standard tidal breathing m...

journal_title：Pediatric pulmonology

authors： Pianosi P,Smith CP,Almudevar A,McGrath PJ

更新日期：2006-12-01 00:00:00

abstract：:In order to better understand the regulation of lung maturation by glucocorticoid-glucocorticoid receptor signaling, we studied glucocorticoid receptor (GR) hypomorphic mice with a mixed C57Bl6/129 sv background, in which disruption of exon 2 of the GR gene produces an N-terminal truncated GR protein. Four groups of m...

journal_title：Pediatric pulmonology

authors： Nemati B,Atmodjo W,Gagnon S,Humes D,McKerlie C,Kaplan F,Sweezey NB

更新日期：2008-02-01 00:00:00

abstract：:This report describes a patient with biliary atresia (BA) associated with polysplenia syndrome who showed a rapid progression of intrapulmonary arteriovenous shunting (IPS), resulting in a fatal outcome. Intrauterine ultrasonography at 36 weeks of gestation revealed fetal abnormalities, including situs inversus, absen...

journal_title：Pediatric pulmonology

authors： Kimura T,Hasegawa T,Sasaki T,Okada A,Mushiake S

更新日期：2003-06-01 00:00:00

abstract：INTRODUCTION:Induced sputum sampling holds promise as a method for obtaining samples representative of the lower airways in young children. Collection of induced sputum samples in young children differs from older children and adults' as pharyngeal suctioning is often required. Our aim was to determine the sensitivity ...

journal_title：Pediatric pulmonology

authors： D'Sylva P,Caudri D,Shaw N,Turkovic L,Douglas T,Bew J,Keil AD,Stick S,Schultz A

更新日期：2017-02-01 00:00:00

abstract：:The quantity and composition of airway surface liquid (ASL) are essential to host defense. To date, attempts to harvest ASL and measure its composition have yielded conflicting results. We investigated the physical principles underlying two techniques that were proposed for harvesting ASL: filter paper pledgets and po...

journal_title：Pediatric pulmonology

authors： Landry JS,Landry C,Cowley EA,Govindaraju K,Eidelman DH

更新日期：2004-02-01 00:00:00

abstract：OBJECTIVE:Lung ultrasound (LUS) is an emerging tool that may be used in the diagnosis and follow-up of children with viral bronchiolitis. In this study, we describe LUS abnormalities in children receiving invasive mechanical ventilation (IMV) for severe bronchiolitis in the pediatric intensive care unit (PICU). Our aim...

journal_title：Pediatric pulmonology

authors： Ingelse SA,Pisani L,Westdorp MHA,Almakdase M,Schultz MJ,van Woensel JBM,Bem RA

更新日期：2020-10-01 00:00:00

abstract：:Neutrophil elastase is present at high levels in airway fluid of patients with cystic fibrosis (CF), and is responsible for considerable inflammatory damage. Human monocyte/neutrophil elastase inhibitor (MNEI), a 42-kDa serpin protein, is an effective inhibitor of neutrophil elastase, cathepsin G, and proteinase-3, re...

journal_title：Pediatric pulmonology

authors： Woods DE,Cantin A,Cooley J,Kenney DM,Remold-O'Donnell E

更新日期：2005-02-01 00:00:00

abstract：:Pseudomonas aeruginosa is often cultured from the airways of children with tracheostomies. P. aeruginosa produces exotoxin A (ETA) and type III cytotoxins. This study tested the hypothesis that children with tracheostomies are colonized by P. aeruginosa that express these virulence factors and will have antibodies dir...

journal_title：Pediatric pulmonology

authors： Rao AR,Splaingard MS,Gershan WM,Havens PL,Thill A,Barbieri JT

更新日期：2005-05-01 00:00:00

abstract：OBJECTIVE:To define the mortality and long-term outcomes of children undergoing tracheostomy. DESIGN:Retrospective chart and Texas Department of Health Bureau of Vital Statistics review of patients admitted to a Pediatric Intensive Care Unit who underwent a tracheostomy between 2001 and 2011. Mortality and decannulati...

journal_title：Pediatric pulmonology

authors： McPherson ML,Shekerdemian L,Goldsworthy M,Minard CG,Nelson CS,Stein F,Graf JM

更新日期：2017-07-01 00:00:00

abstract：:Electronic compensation to overcome thermal artifacts during plethysmographic estimations of airway resistance is now used routinely in adults and school-age children, and was shown to be a valuable means of discriminating airway function between preschool children with and without lung disease. A similar system is no...

journal_title：Pediatric pulmonology

authors： Subbarao P,Hulskamp G,Stocks J

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:In preschool children, measurement of airway resistance using interrupter technique (Rint) is feasible to assess the degree of bronchial obstruction. Although some studies measured Rint in infancy, values of Rint and its variability in preterm infants are unknown. In this study, Rint and its variability was ...

journal_title：Pediatric pulmonology

authors： Usemann J,Demann D,Anagnostopoulou P,Korten I,Gorlanova O,Schulzke S,Frey U,Latzin P

更新日期：2017-10-01 00:00:00

abstract：:Our objective was to review the clinical features and radiographic manifestations of chest wall lesions in a pediatric chest unit. Twenty-five patients (11 males and 14 females, aged 14 months to 15 years) were suspected of having a chest wall lesion on the basis of clinical examination and chest radiograph. A retrosp...

journal_title：Pediatric pulmonology

authors： Wong KS,Hung IJ,Wang CR,Lien R

更新日期：2004-03-01 00:00:00

abstract：OBJECTIVES:High incidence of genetic alterations at the microsatellite (MS) DNA level has been reported in asthmatic adults. WORKING HYPOTHESIS:The aim of this study was to investigate whether microsatellite instability (MSI) and loss of heterozygosity (LOH) were detectable phenomena in children with asthma. METHODOL...

journal_title：Pediatric pulmonology

authors： Thomou C,Paraskakis E,Neofytou E,Kalmanti M,Siafakas NM,Tzortzaki EG

更新日期：2009-10-01 00:00:00

abstract：OBJECTIVES:Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections worldwide, causing disproportionate morbidity and mortality in infants and children. Infants with stronger Th1 responses have less severe disease, yet little is known about the infant T-cell response within the air spa...

journal_title：Pediatric pulmonology

authors： Eichinger KM,Kosanovich JL,Empey KM

更新日期：2018-02-01 00:00:00

abstract：:We present a child with interstitial lung disease (ILD) who was diagnosed with desquamative interstitial pneumonitis following CT thorax and open lung biopsy aged 2 years. Subsequently, surfactant protein gene analysis revealed mutations in the ABCA3 gene. This case of ABCA3 deficient ILD describes a stable clinical c...

journal_title：Pediatric pulmonology

authors： Williamson M,Wallis C

更新日期：2014-03-01 00:00:00

abstract：:The structure, distribution, and frequency of neuroendocrine (NE) cells in human fetal lung from early stages of development to term are described. Neuroendocrine cells were studied by electron microscopy and immunostaining for serotonin and bombesin, recently identified markers of these cells in human lung. The diffe...

journal_title：Pediatric pulmonology

authors： Cutz E,Gillan JE,Bryan AC

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Magnetic Resonance Imaging (MRI) techniques to image the larynx have evolved rapidly into a promising and safe imaging modality, without need for sedation or ionizing radiation. MRI is therefore of great interest to image pediatric laryngeal diseases. Our aim was to review MRI developments relevant for the p...

journal_title：Pediatric pulmonology

authors： Elders BBLJ,Hermelijn SM,Tiddens HAWM,Pullens B,Wielopolski PA,Ciet P

更新日期：2019-04-01 00:00:00

abstract：:Sudden unexplained deaths have been reported in 13% [corrected] of Familial Dysautonomia (FD) subjects. To characterize cardiorespiratory dysregulation in children with FD that might contribute to potential sudden death, respiratory inductance plethysmography (chest/abdomen), ECG, hemoglobin saturation, and pulse wave...

journal_title：Pediatric pulmonology

authors： Weese-Mayer DE,Kenny AS,Bennett HL,Ramirez JM,Leurgans SE

更新日期：2008-03-01 00:00:00

abstract：:We measured then compared the dynamic lung mechanics of spontaneous breaths and mechanical breaths in 9 mechanically ventilated neonates with hyaline membrane disease. All were receiving intermittent mandatory ventilation. All breathed spontaneously between ventilator breaths. Tidal volume, transpulmonary pressure, dy...

journal_title：Pediatric pulmonology

authors： Mammel MC,Fisher JB,Bing DR,Gatto CW,Boros SJ

更新日期：1990-01-01 00:00:00

abstract：:Inhalation therapy for wheezy infants with either a nebulizer or a pressurized metered-dose inhaler (pMDI) through a spacer is common practice. The aim of our study was to compare aerosol delivery to wheezy infants from a nebulizer and from a pMDI via two small volume spacers. Twenty wheezy infants (aged 4-12 months) ...

journal_title：Pediatric pulmonology

authors： Wildhaber JH,Devadason SG,Hayden MJ,Eber E,Summers QA,LeSouëf PN

更新日期：1997-03-01 00:00:00