Acquired somatic mutations in the microsatellite DNA, in children with bronchial asthma.

abstract：BACKGROUND:Chronic colonization with Pseudomonas (P.) aeruginosa worsens the prognosis of cystic fibrosis (CF) patients. This study aims to analyze the functional properties of neutrophils in CF patients with P. aeruginosa colonization. METHODS:Patients with CF (n = 16) were grouped by positivity of P. aeruginosa in s...

journal_title：Pediatric pulmonology

authors： Aslanhan U,Cakir E,Ozyigit LP,Kucuksezer UC,Gelmez YM,Yuksel M,Deniz G,Aktas EC

更新日期：2021-01-29 00:00:00

abstract：:During the past five decades there has been increasing interest in the potential anti-inflammatory effects of macrolide antibiotics. Low-dose macrolide therapy has dramatically increased survival in patients with diffuse panbronchiolitis, a disease with many similarities to cystic fibrosis (CF). This has led to furthe...

journal_title：Pediatric pulmonology

authors： Jaffé A,Bush A

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:Night-time symptoms and hypoxemia during sleep may affect sleep quality in children with chronic lung disease such as bronchiectasis. Poor sleep quality may impair growth, learning, and emotional development of children. Our aim was to assess the sleep quality and associated factors in children with non-cyst...

journal_title：Pediatric pulmonology

authors： Erdem E,Ersu R,Karadag B,Karakoc F,Gokdemir Y,Ay P,Akpinar IN,Dagli E

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVES:In hospitalized and nonhospitalized children with asthma exacerbations, we evaluated the determinants of (a) prolonged cough on day-14 and (b) asthma quality of life (QoL) questionnaires for parents (PACQLQ) on day-21. We hypothesized that children with more severe acute asthma are more likely to have prolon...

journal_title：Pediatric pulmonology

authors： Teoh L,Chatfield MD,Acworth JP,McCallum GB,Chang AB

更新日期：2020-11-12 00:00:00

abstract：:Spontaneous hemopneumothorax (SHP) is a rare potentially life-threatening condition that occurs in predominantly young adolescents. The resultant massive hemorrhage leading to hypovolemic shock can be a surgical emergency. It constitutes 1-12% of all spontaneous pneumothoraces and presents with two cardinal features, ...

journal_title：Pediatric pulmonology

authors： Chen TH,Tseng YH,Tseng CM,Chiang HH,Lin TJ

更新日期：2014-01-01 00:00:00

abstract：BACKGROUND:Asthma and obstructive sleep apnea (OSA) in children share multiple epidemiological risk factors and the prevalence of snoring is higher in asthmatic children, suggesting that the latter may be at increased risk for OSA. Since both asthma and OSA are inflammatory disorders, we hypothesized that polysomnograp...

journal_title：Pediatric pulmonology

authors： Kheirandish-Gozal L,Dayyat EA,Eid NS,Morton RL,Gozal D

更新日期：2011-09-01 00:00:00

abstract：:There is a need to judge general exercise tolerance in children with cystic fibrosis (CF) under normal daily activity conditions and -when more extensive testing is required-in an exercise laboratory in a specialized center. We investigated the reproducibility, validity, and criterion for a 6-minute walking test, whic...

journal_title：Pediatric pulmonology

authors： Gulmans VA,van Veldhoven NH,de Meer K,Helders PJ

更新日期：1996-08-01 00:00:00

abstract：OBJECTIVE:Both healthy preterm infants and those with bronchopulmonary dysplasia (BPD) have poor lung function during childhood and adolescence, although there is no evidence whether prematurity alone explains the reduction in lung function found in BPD infants. Our study seeks to know if lung function, measured in inf...

journal_title：Pediatric pulmonology

authors： Sanchez-Solis M,Garcia-Marcos L,Bosch-Gimenez V,Pérez-Fernandez V,Pastor-Vivero MD,Mondéjar-Lopez P

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:In preschool children, measurement of airway resistance using interrupter technique (Rint) is feasible to assess the degree of bronchial obstruction. Although some studies measured Rint in infancy, values of Rint and its variability in preterm infants are unknown. In this study, Rint and its variability was ...

journal_title：Pediatric pulmonology

authors： Usemann J,Demann D,Anagnostopoulou P,Korten I,Gorlanova O,Schulzke S,Frey U,Latzin P

更新日期：2017-10-01 00:00:00

abstract：:Pulmonary surfactant, a unique developmentally regulated, phospholipid-rich lipoprotein, is synthesized by the type II epithelial cells (AECII) of the pulmonary alveolus, where it is stored in organelles termed lamellar bodies. The synthesis of pulmonary surfactant is under multifactorial control and is regulated by a...

journal_title：Pediatric pulmonology

authors： Zhang XQ,Zhang P,Yang Y,Qiu J,Kan Q,Liang HL,Zhou XY,Zhou XG

更新日期：2014-09-01 00:00:00

abstract：INTRODUCTION:Acute bronchiolitis is a major cause of acute respiratory distress in infants. The soluble receptor for advanced glycation end-products (sRAGE) is a biomarker of pulmonary damage processes, with a diagnostic and a prognostic value in acute respiratory distress syndrome (ARDS). The RAGE pathway is also impl...

journal_title：Pediatric pulmonology

authors： Egron C,Roszyk L,Rochette E,Jabaudon M,Sapin V,Mulliez A,Labbé A,Coste K

更新日期：2018-10-01 00:00:00

abstract：BACKGROUND:The aim of this study was to investigate the association among a validated symptom-based questionnaire for asthma control in children (CAN), forced expiratory volume in 1 sec (FEV(1)), and fractional exhaled nitric oxide (FE(NO)). METHODS:Observational cross-sectional study was performed in a consecutive sa...

journal_title：Pediatric pulmonology

authors： Sardón-Prado O,Korta-Murua J,Valverde-Molina J,Fernández-Paredes JJ,Mintegui J,Corcuera-Elosegui P,Emparanza JI,Pérez-Yarza EG

更新日期：2010-05-01 00:00:00

abstract：:Thirteen children with asthma were treated with cumulative doses of terbutaline delivered as a pressurized aerosol and from a new multidose powder inhaler (Turbuhaler) in a randomized cross-over dose-response study. The cumulative dose of terbutaline was 2 mg on each study day. All children used a correct aerosol inha...

journal_title：Pediatric pulmonology

authors： Fuglsang G,Pedersen S

更新日期：1989-01-01 00:00:00

abstract：:Four patients with severe cystic fibrosis lung disease, anorexia and weight loss, received Megestrol Acetate (MA), as an appetite stimulant. The initial dose was 400-800 mg daily and was continued for 6-15 months. Appetite was improved, with significant weight gain in all patients and an increase in their weight for a...

journal_title：Pediatric pulmonology

authors： Nasr SZ,Hurwitz ME,Brown RW,Elghoroury M,Rosen D

更新日期：1999-11-01 00:00:00

abstract：:Our objective was to study meconium-induced lung injury in isolated perfused rat lungs exposed to anoxia. Our working hypothesis was that meconium-induced lung injury is independent of preexisting hypoxia, and that hypoxia will increase severity of lung injury observed after meconium aspiration. We compared five diffe...

journal_title：Pediatric pulmonology

authors： Wisniewski WM,Zagariya AM,Pavuluri N,Srinivasan H,Shankarao S,Vidyasagar D

更新日期：2005-04-01 00:00:00

abstract：AIM:Magnesium is an adjunctive therapy used in patients with status asthmaticus who do not respond to conventional therapy. The optimal time from initiation of therapy, to determination of response and administration of magnesium has not yet been resolved. Our objective was to determine if magnesium administered in the...

journal_title：Pediatric pulmonology

authors： DeSanti RL,Agasthya N,Hunter K,Hussain MJ

更新日期：2018-07-01 00:00:00

abstract：OBJECTIVE:To determine the interpretative consequences of adopting the Global Lungs 2012 (GLI-2012) spirometric prediction equations in a pediatric hospital population. MATERIAL:Spirometric records from 2,192 white boys and 1,842 white girls, and 412 and 334 African-American boys and girls, respectively, aged 6.0-18.0...

journal_title：Pediatric pulmonology

authors： Quanjer PH,Weiner DJ

更新日期：2014-02-01 00:00:00

abstract：:The analysis of exhaled breath condensate (EBC) is a promising new method to measure airway inflammation. So far only limited data exist about methodological issues of EBC sampling in infants and young children. We evaluated 18 children with acute wheezy bronchitis (median age 24.3 months (min-max: 4-89.9)), 54 childr...

journal_title：Pediatric pulmonology

authors： Vogelberg C,Würfel C,Knoetzsch A,Kahlert A,Range U,Leupold W

更新日期：2007-12-01 00:00:00

abstract：:This paper assesses the effectiveness of aerosolized tobramycin (TOBI) on cystic fibrosis (CF) lung disease, using a radiologic tool. The published tool, the age-based severity curve (ABS), is derived from Brasfield scoring of chest X-rays (CXR). This study evaluates both the usefulness of the ABS as an assessment too...

journal_title：Pediatric pulmonology

authors： Slattery DM,Zurakowski D,Colin AA,Cleveland RH

更新日期：2004-07-01 00:00:00

abstract：:To develop and validate a questionnaire scale that can be used as a screening tool to investigate for the presence of childhood obstructive sleep apnea syndrome (OSAS) in Hong Kong Chinese children. Subjects suspected to have OSAS and controls were recruited. Parents completed a Hong Kong children sleep questionnaire ...

journal_title：Pediatric pulmonology

authors： Li AM,Cheung A,Chan D,Wong E,Ho C,Lau J,Wing YK

更新日期：2006-12-01 00:00:00

abstract：:Wheezing is the most widely reported adventitious lung sound in the English language. It is recognized by health professionals as well as by lay people, although often with a different meaning. Wheezing is an indicator of airway obstruction and therefore of interest particularly for the assessment of young children an...

journal_title：Pediatric pulmonology

authors： Pasterkamp H

更新日期：2018-02-01 00:00:00

abstract：:Tracheobronchomegaly (Mounier-Kuhn syndrome) is characterized by dilatation of the central airways, tracheobronchial outpouchings, and chronic tracheobronchitis. Most cases are diagnosed in adulthood. We report the clinical, radiographic, and bronchoscopic findings in a 14-year-old boy with tracheobronchomegaly, ptosi...

journal_title：Pediatric pulmonology

authors： Benesch M,Eber E,Pfleger A,Zach MS

更新日期：2000-06-01 00:00:00

abstract：:This report describes a patient with biliary atresia (BA) associated with polysplenia syndrome who showed a rapid progression of intrapulmonary arteriovenous shunting (IPS), resulting in a fatal outcome. Intrauterine ultrasonography at 36 weeks of gestation revealed fetal abnormalities, including situs inversus, absen...

journal_title：Pediatric pulmonology

authors： Kimura T,Hasegawa T,Sasaki T,Okada A,Mushiake S

更新日期：2003-06-01 00:00:00

abstract：BACKGROUND:Asthma is the most common chronic inflammatory disease in childhood and some reports have demonstrated systemic inflammation. The relevance of high-sensitivity assays for C-reactive protein (hs-CRP), which are known to be a sensitive marker of low-grade systemic inflammation, has not been fully studied in ch...

journal_title：Pediatric pulmonology

authors： Deraz TE,Kamel TB,El-Kerdany TA,El-Ghazoly HM

更新日期：2012-03-01 00:00:00

abstract：PURPOSE:To investigate the common indications for polysomnogram (PSG) associated co-morbid conditions, evaluation strategies, treatment options, and outcomes in a series of infants diagnosed with obstructive sleep apnea (OSA) by a PSG. METHODS:Retrospective chart review of infants who underwent PSG over a 7-year perio...

journal_title：Pediatric pulmonology

authors： Ramgopal S,Kothare SV,Rana M,Singh K,Khatwa U

更新日期：2014-06-01 00:00:00

abstract：:The aim of this study was to examine a possible association between birth season (date of birth) and future development of asthma in children. A case-control study was designed to include asthmatic children aged 2-7 years, living in the city of Beer-Sheva, in southern Israel, registered in one pediatric center. Contro...

journal_title：Pediatric pulmonology

authors： Gazala E,Ron-Feldman V,Alterman M,Kama S,Novack L

更新日期：2006-12-01 00:00:00

abstract：:Two male patients with cystic fibrosis (CF), both 18 years old, developed frontal lobe brain abscesses. Both patients presented with histories of intermittent headache over several days and occasional vomiting. Headache was not more evident in the mornings and not associated with visual disturbance in either patient. ...

journal_title：Pediatric pulmonology

authors： Cooper DM,Russell LE,Henry RL

更新日期：1994-06-01 00:00:00

abstract：:The main purpose of this study was to evaluate four different forms of treatment in young infants admitted for acute wheezing (AW). Seventy-nine infants less than one year of age were randomly assigned to one of five groups. Group 1 received nebulized fenoterol plus ipratropium bromide, group 2 fenoterol, group 3 feno...

journal_title：Pediatric pulmonology

authors： Mallol J,Barrueto L,Girardi G,Muñoz R,Puppo H,Ulloa V,Toro O,Quevedo F

更新日期：1987-09-01 00:00:00

abstract：:The prevalence and morbidity of asthma are growing problems that appear to affect urban populations and particularly impoverished centers disproportionately. Poor children are more likely to be hospitalized for asthma than nonpoor children, and are more likely to experience clinical and social dysfunction due to asthm...

journal_title：Pediatric pulmonology

authors： Shapiro GG,Stout JW

更新日期：2002-01-01 00:00:00

abstract：:Phrenic nerve paralysis is a condition typically occurring after invasive procedures in the chest and neck. Here we describe a case of transient unilateral diaphragmatic paralysis in a child with status asthmaticus complicated by complete right lung atelectasis. Common causes of this disorder and possible implications...

journal_title：Pediatric pulmonology

authors： Santuz P,Piccoli A,Zaglia F,Biban P

更新日期：2004-09-01 00:00:00