Use of nebulized bronchodilators in infants under 1 year of age: analysis of four forms of therapy.

abstract：BACKGROUND:Children with adenoid hypertrophy (AH) have impaired respiratory system defense mechanisms, such as mucociliary clearance. We hypothesized that AH negatively affects one of the most important aspects of mucociliary clearance-ciliary beat frequency (CBF) and that adenoidectomy could potentially restore this e...

journal_title：Pediatric pulmonology

authors： Marusiakova L,Durdik P,Jesenak M,Bugova G,Kvassayova J,Oppova D,Banovcin P

更新日期：2020-03-01 00:00:00

abstract：:Neonatal exposure to intermittent hypoxia results in altered ventilatory response to subsequent hypoxia in animal models. The effect of similar exposure in human infants is unknown. Our objective was to determine the impact of sleep disordered breathing (SDB) in early infancy on ventilatory response in infants. We rec...

journal_title：Pediatric pulmonology

authors： MacLean JE,Tan S,Fitzgerald DA,Waters KA

更新日期：2013-03-01 00:00:00

abstract：:There is increasing interest in using the Multiple Breath Washout technique and the lung clearance index (LCI) for detecting early pulmonary changes, for example, in cystic fibrosis lung disease. However, there are still limited data regarding equipment specific reference ranges, repeatability and reproducibility. The...

journal_title：Pediatric pulmonology

authors： Fuchs SI,Eder J,Ellemunter H,Gappa M

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:In young children with cystic fibrosis (CF) the forced expiratory volume in 1 second (FEV1 ) is often normal and a more sensitive measure to detect early obstructive lung disease is needed. AIM:To evaluate the progression of selected spirometry parameters with age in a cohort of CF patients and healthy chil...

journal_title：Pediatric pulmonology

authors： Bakker EM,Borsboom GJ,van der Wiel-Kooij EC,Caudri D,Rosenfeld M,Tiddens HA

更新日期：2013-11-01 00:00:00

abstract：:The long-term efficacy and safety of aminoglycoside aerosol therapy for Pseudomonas aeruginosa colonization/infection in cystic fibrosis has not been fully investigated. In the present study, 14 patients with cystic fibrosis, ages 8-19 years (mean: 13.3 years), received tobramycin aerosol therapy for a mean duration o...

journal_title：Pediatric pulmonology

authors： Steinkamp G,Tümmler B,Gappa M,Albus A,Potel J,Döring G,von der Hardt H

更新日期：1989-01-01 00:00:00

abstract：:Multiresistance in Stenotrophomonas maltophilia limits the effectiveness of antimicrobial therapy for infections due to this organism. It can be of special concern in cystic fibrosis (CF) patients due to frequent antimicrobial administration. The in vitro activity of 41 antimicrobial agents against 76 epidemiologicall...

journal_title：Pediatric pulmonology

authors： Cantón R,Valdezate S,Vindel A,Sánchez Del Saz B,Maíz L,Baquero F

更新日期：2003-02-01 00:00:00

abstract：:Maternal retinoid administration has beneficial effects on lung development in the nitrofen rodent toxic model of congenital diaphragmatic hernia (DH). We wanted to investigate the effects in a surgical model, where the retinoid signaling pathway is not primarily disrupted by the toxic agent. We created DH in fetal ra...

journal_title：Pediatric pulmonology

authors： Gallot D,Coste K,Jani J,Roubliova X,Marceau G,Velemir L,Verheyen A,Lemery D,Sapin V,Deprest J

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Pressure rise time (PRT), also known as slope time to the peak inflating pressure can be set on some modern neonatal ventilators. On other ventilators, PRT is determined by the set circuit flow. Changing slope time can affect mean airway pressure (MAP), oxygenation, and carbon dioxide elimination. Our aim wa...

journal_title：Pediatric pulmonology

authors： Chong D,Kayser S,Szakmar E,Morley CJ,Belteki G

更新日期：2020-05-01 00:00:00

abstract：:To determine the extent of pulmonary dysfunction following primary closure of an abdominal wall defect, we obtained pulmonary function tests (PFT) in 11 newborn infants with gastroschisis and 6 with large omphaloceles admitted to a newborn ICU in a children's hospital. Patients were 1 to 30 days of age at the time of ...

journal_title：Pediatric pulmonology

authors： Nakayama DK,Mutich R,Motoyama EK

更新日期：1992-03-01 00:00:00

abstract：:Follow-up studies have demonstrated that bronchiolitis caused by respiratory syncytial virus (RSV) is strongly associated with wheezing in the ensuing years. During the acute infection the immune response may induce long-lasting detrimental effects, thereby contributing to post-bronchiolitis wheezing (PBW). Therefore,...

journal_title：Pediatric pulmonology

authors： van Woensel JB,Kimpen JL,Sprikkelman AB,Ouwehand A,van Aalderen WM

更新日期：2000-08-01 00:00:00

abstract：:Forced oscillatory respiratory resistance was measured in 138 healthy children aged 2- to 16-years-old using a commercial unit. Regression analysis was performed using the resistance measurements obtained at frequencies of 6 Hz and 26 Hz and averages of measurements obtained at frequencies of from 6-26 Hz, 6-10 Hz, an...

journal_title：Pediatric pulmonology

authors： Hordvik NL,König P,Morris DA,Kreutz C,Pimmel RL

更新日期：1985-05-01 00:00:00

abstract：:Bronchiolitis in infancy is a risk factor for development of asthma in the first decades of life, although the majority may be asymptomatic at school age. Respiratory symptoms are common in early life, and prediction of later asthma may be challenging. We aimed to study if simple clinical variables assessed at 2 years...

journal_title：Pediatric pulmonology

authors： Mikalsen IB,Halvorsen T,Eide GE,Øymar K

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Matrix metalloproteinase-9 (MMP-9) plasma levels correlate with C-reactive protein (CRP) concentrations and they are both increased in adults with obstructive sleep apnea (OSA). No studies have evaluated MMP-9 levels in children with sleep apnea and CRP is not consistently elevated in pediatric OSA. The aim ...

journal_title：Pediatric pulmonology

authors： Kaditis AG,Alexopoulos EI,Karathanasi A,Ntamagka G,Oikonomidi S,Kiropoulos TS,Zintzaras E,Gourgoulianis K

更新日期：2010-07-01 00:00:00

abstract：:Pediatric Pulmonology continues to publish research and clinical topics related to the entire range of children's respiratory disorders. As we have done annually in recent years, we here summarize some of the past year's publications in our major topic areas, as well as selected literature in these areas from other co...

journal_title：Pediatric pulmonology

authors： Auten R,Ren C,Yilmaz O,Noah TL

更新日期：2017-09-01 00:00:00

abstract：:Antimicrobial proteins are important in lung defense and are potential therapeutic agents in chronic airways infection such as seen in cystic fibrosis (CF). In preparation for future clinical studies, we sought (1) to determine levels of three antimicrobial proteins [lactoferrin, lysozyme, and secretory leukoprotease ...

journal_title：Pediatric pulmonology

authors： Sagel SD,Sontag MK,Accurso FJ

更新日期：2009-04-01 00:00:00

abstract：OBJECTIVE:Lung ultrasound (LUS) is an emerging tool that may be used in the diagnosis and follow-up of children with viral bronchiolitis. In this study, we describe LUS abnormalities in children receiving invasive mechanical ventilation (IMV) for severe bronchiolitis in the pediatric intensive care unit (PICU). Our aim...

journal_title：Pediatric pulmonology

authors： Ingelse SA,Pisani L,Westdorp MHA,Almakdase M,Schultz MJ,van Woensel JBM,Bem RA

更新日期：2020-10-01 00:00:00

abstract：OBJECTIVES:First, create a clinical severity score for patients with chronic lung disease of infancy (CLDi) following neonatal intensive care unit (NICU) stay. Second, using California wide population-based data, identify factors associated with clinical severity of CLDi at 4-9 months corrected gestational age (CGA). ...

journal_title：Pediatric pulmonology

authors： Gage S,Kan P,Oehlert J,Gould JB,Stevenson DK,Shaw GM,O'Brodovich HM

更新日期：2015-09-01 00:00:00

abstract：:The raised lung volume technique is increasingly used to measure forced expiratory maneuvers in infants. However, there is no consensus regarding the optimal airway inflation pressure (P(inf)) required for such maneuvers, or the influence of small changes in P(inf) within and between infants. The aim of this study was...

journal_title：Pediatric pulmonology

authors： Lum S,Hoo AF,Stocks J

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Ivacaftor is a significant innovation in the treatment of cystic fibrosis (CF) with gating mutations. A substantial percentage of patients with CF have severe lung involvement, but these patients are usually excluded from phase III clinical trials. Thus, the effectiveness of ivacaftor in this population has ...

journal_title：Pediatric pulmonology

authors： Salvatore D,Carnovale V,Iacotucci P,Braggion C,Castellani C,Cimino G,Colangelo C,Francalanci M,Leonetti G,Lucidi V,Manca A,Vitullo P,Ferrara N

更新日期：2019-09-01 00:00:00

abstract：:Impulse oscillometry (IOS) evaluates non-effort-dependent respiratory mechanics, and thus it may be useful to evaluate patients with Duchenne muscular dystrophy (DMD). OBJECTIVES:We aimed (1) to describe the behavior of IOS parameters in patients with DMD, and compare it to those from a control group; (2) to determin...

journal_title：Pediatric pulmonology

authors： Gochicoa-Rangel L,Vargas MH,Alonso-Gómez JL,Rodríguez-Moreno L,Martínez-Briseño D,Baños-Mejía O,Torre-Bouscoulet L

更新日期：2016-10-01 00:00:00

abstract：:The prognosis for patients with acute respiratory distress syndrome (ARDS) in adults and children has improved since its formal acceptance as a clinical entity in 1967. Because acute hypoxemic respiratory failure is the hallmark of acute lung injury and ARDS, the management of oxygenation is crucial. Physicians managi...

journal_title：Pediatric pulmonology

authors： Matthews BD,Noviski N

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:Asthma is a disease with reversible bronchoconstriction; however, some patients develop fixed airflow obstruction (FAO). Previous studies have reported the incidence and risk factors of FAO in adults; however, the corresponding factors in children remain poorly understood. AIM:To evaluate the incidence and ...

journal_title：Pediatric pulmonology

authors： Sousa AW,Barros Cabral AL,Arruda Martins M,Carvalho CRF

更新日期：2020-03-01 00:00:00

abstract：:We determined lung function at age 10 years in very low birthweight (VLBW,

journal_title：Pediatric pulmonology

authors： Palta M,Sadek-Badawi M,Madden K,Green C

更新日期：2007-09-01 00:00:00

abstract：:Two male patients with cystic fibrosis (CF), both 18 years old, developed frontal lobe brain abscesses. Both patients presented with histories of intermittent headache over several days and occasional vomiting. Headache was not more evident in the mornings and not associated with visual disturbance in either patient. ...

journal_title：Pediatric pulmonology

authors： Cooper DM,Russell LE,Henry RL

更新日期：1994-06-01 00:00:00

abstract：OBJECTIVES:Sildenafil, tezosentan, and prostacyclin reduce pulmonary vascular pressures in pulmonary hypertension, but have potential to vasodilate the systemic circulation. Nebulized vasodilators allow targeted drug delivery, high local drug concentrations, less systemic hypotension, and better matching of the lung's ...

journal_title：Pediatric pulmonology

authors： Katz SL,Adatia I,Louca E,Leung K,Humpl T,Reyes JT,Coates AL

更新日期：2006-07-01 00:00:00

abstract：RATIONALE:Secondhand smoke (SHS) has deleterious respiratory, immune, and nutritional effects in children, but there is little data regarding the effects of SHS exposure in infants with cystic fibrosis (CF). METHODS:A retrospective chart review was undertaken from 2008 to 2012 of 75 infants with CF. Growth, lung funct...

journal_title：Pediatric pulmonology

authors： Kopp BT,Sarzynski L,Khalfoun S,Hayes D Jr,Thompson R,Nicholson L,Long F,Castile R,Groner J

更新日期：2015-01-01 00:00:00

abstract：:We enrolled 30 infants (median age 3 months, range 1-12 months), hospitalized for bronchiolitis in a randomized double-blind trial, to examine the efficacy and safety of nebulized epinephrine compared to salbutamol. Once admitted, patients were treated with either nebulized 0.5 mg of an 0.1% epinephrine solution (0.5 ...

journal_title：Pediatric pulmonology

authors： Bertrand P,Araníbar H,Castro E,Sánchez I

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Chronic colonization with Pseudomonas (P.) aeruginosa worsens the prognosis of cystic fibrosis (CF) patients. This study aims to analyze the functional properties of neutrophils in CF patients with P. aeruginosa colonization. METHODS:Patients with CF (n = 16) were grouped by positivity of P. aeruginosa in s...

journal_title：Pediatric pulmonology

authors： Aslanhan U,Cakir E,Ozyigit LP,Kucuksezer UC,Gelmez YM,Yuksel M,Deniz G,Aktas EC

更新日期：2021-01-29 00:00:00

abstract：:Diffuse panbronchiolitis is a progressive fatal respiratory disease of unknown cause seen predominantly in Southeast Asian adults. We report this condition in a 10-year-old child of Korean birth because of the uncommon presentation at this age and the favorable outcome associated with early diagnosis. Our objective wa...

journal_title：Pediatric pulmonology

authors： Weinberger M,Fischer A,Kao S

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVES:Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections worldwide, causing disproportionate morbidity and mortality in infants and children. Infants with stronger Th1 responses have less severe disease, yet little is known about the infant T-cell response within the air spa...

journal_title：Pediatric pulmonology

authors： Eichinger KM,Kosanovich JL,Empey KM

更新日期：2018-02-01 00:00:00