Treatment of anorexia and weight loss with megestrol acetate in patients with cystic fibrosis.

Abstract:

:Four patients with severe cystic fibrosis lung disease, anorexia and weight loss, received Megestrol Acetate (MA), as an appetite stimulant. The initial dose was 400-800 mg daily and was continued for 6-15 months. Appetite was improved, with significant weight gain in all patients and an increase in their weight for age percentile from <5% at the start of the study to approximately the 25(th) percentile after 6 months of use and improvement in quality of life. One patient discontinued MA after 6 months, and subsequently appetite and weight were depressed.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Nasr SZ,Hurwitz ME,Brown RW,Elghoroury M,Rosen D

doi

10.1002/(sici)1099-0496(199911)28:5<380::aid-ppul1

subject

Has Abstract

pub_date

1999-11-01 00:00:00

pages

380-2

issue

5

eissn

8755-6863

issn

1099-0496

pii

10.1002/(SICI)1099-0496(199911)28:5<380::AID-PPUL1

journal_volume

28

pub_type

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