Anti-inflammatory effects of macrolides in lung disease.

abstract：:Deficiency of mannose-binding lectin has been shown to be a risk factor for cystic fibrosis (CF) patients. We, therefore, decided to treat a patient with CF, mannose-binding lectin deficiency, severe bronchopulmonary Pseudomonas aeruginosa infection, and rapid deterioration of lung function with purified mannose-bindi...

journal_title：Pediatric pulmonology

authors： Garred P,Pressler T,Lanng S,Madsen HO,Moser C,Laursen I,Balstrup F,Koch C,Koch C

更新日期：2002-03-01 00:00:00

abstract：:Malacoplakia is an unusual inflammatory condition with distinctive histologic features. Involvement of the lung is quite uncommon and is rarely described in paediatrics. We report on a case of pulmonary malacoplakia in a teenage girl. ...

journal_title：Pediatric pulmonology

authors： Kumar P,Rassl DM,Hamilton JR,Spencer DA

更新日期：2003-11-01 00:00:00

abstract：:A 14-year-old Korean boy was admitted with cough, hemoptysis, and fever. A chest X-ray showed a solitary pulmonary mass and pneumonitis. Bronchial biopsy by fiberoptic bronchoscopy revealed a poorly differentiated small cell carcinoma. All of the staging information indicated that the patient had limited disease. Duri...

journal_title：Pediatric pulmonology

authors： Kim CK,Chung CY,Koh YY

更新日期：2000-04-01 00:00:00

abstract：:Impulse oscillometry (IOS) evaluates non-effort-dependent respiratory mechanics, and thus it may be useful to evaluate patients with Duchenne muscular dystrophy (DMD). OBJECTIVES:We aimed (1) to describe the behavior of IOS parameters in patients with DMD, and compare it to those from a control group; (2) to determin...

journal_title：Pediatric pulmonology

authors： Gochicoa-Rangel L,Vargas MH,Alonso-Gómez JL,Rodríguez-Moreno L,Martínez-Briseño D,Baños-Mejía O,Torre-Bouscoulet L

更新日期：2016-10-01 00:00:00

abstract：BACKGROUND:Several studies have shown that exposure to air pollutants affects lung growth and development and can result in poor respiratory health in early life. METHODS:We included a subsample of 772 Mexican preschoolers whose mothers participated in a Prenatal Omega-3 fatty acid Supplements, GRowth, And Development...

journal_title：Pediatric pulmonology

authors： Gutiérrez-Delgado RI,Barraza-Villarreal A,Escamilla-Núñez MC,Hernández-Cadena L,Cortez-Lugo M,Sly P,Romieu I

更新日期：2020-08-01 00:00:00

abstract：:Viral colds are an important cause of respiratory symptoms in normal children. Studies in adults suggest that inflammation in the lower respiratory tract is associated with viral colds, but there are no data regarding inflammation and viral infection in the lower airway of normal children with colds. We, therefore, st...

journal_title：Pediatric pulmonology

authors： Grigg J,Riedler J,Robertson CF

更新日期：1999-08-01 00:00:00

abstract：:Nicotine, 1 mg/kg body weight/day, was injected subcutaneously in 3 female rabbits during gestational and lactating periods, and the lungs of the offspring were studied by scanning and transmission electron microscopy (SEM and TEM) on days 5, 10, and 25 postpartum. Three other female rabbits served as controls. The si...

journal_title：Pediatric pulmonology

authors： Chen MF,Diotallevi MJ,Kimizuka G,King M,Wang NS

更新日期：1985-11-01 00:00:00

abstract：:Asthma has been found related to a higher risk of psychological problems. Inconsistent results have been reported with respect to the quality of life of children with asthma. So there may be a complex relationship between asthma severity, quality of life, and psychological factors. The aim of this study was to examine...

journal_title：Pediatric pulmonology

authors： Goldbeck L,Koffmane K,Lecheler J,Thiessen K,Fegert JM

更新日期：2007-01-01 00:00:00

abstract：:Standard chemotherapy for tuberculosis (TB) in children uses hepatotoxic drugs. Published data and guidelines on monitoring of liver function during TB treatment are often contradictory and not directly relevant to the pediatric population. We carefully monitored 43 children (age 6.6 years, 0.7-15.1 [median, range]; 4...

journal_title：Pediatric pulmonology

authors： Corrigan D,Paton J

更新日期：1999-01-01 00:00:00

abstract：:Between October, 1985 and May 1987, 29 children (mean age 22 +/- 22 months, range 2-54 months) with AIDS or ARC developed acute respiratory illness. The initial diagnostic procedure was flexible fiberoptic bronchoscopy, with bronchoalveolar lavage (BAL). BAL was positive for Pneumocystis carinii in 14 and for respirat...

journal_title：Pediatric pulmonology

authors： Bye MR,Bernstein L,Shah K,Ellaurie M,Rubinstein A

更新日期：1987-11-01 00:00:00

abstract：:The purpose of the study was to analyze the respiratory-dependent intraarterial blood pressure variations (pulsus paradoxus, PP) in intensive care unit patients with obstructive and restrictive pulmonary disease, and to evaluate the usefulness of PP for assessment of disease severity. One-minute paper recordings of ar...

journal_title：Pediatric pulmonology

authors： Frey B,Freezer N

更新日期：2001-02-01 00:00:00

abstract：:Oxygen supplementation may improve exercise tolerance and the physiological response to exercise in cystic fibrosis (CF) patients. Elevated barometric pressure at low altitude is a simple means of increasing the quantity of inspired oxygen. Our objectives were to examine the effect of natural oxygen enrichment (at the...

journal_title：Pediatric pulmonology

authors： Falk B,Nini A,Zigel L,Yahav Y,Aviram M,Rivlin J,Bentur L,Avital A,Dotan R,Blau H

更新日期：2006-03-01 00:00:00

abstract：:Respiration rate is an important indicator of a person's health, and thus it is monitored when performing clinical evaluations. There are different approaches for respiration monitoring, but generally they can be classed as contact or noncontact. For contact methods, the sensing device (or part of the instrument conta...

journal_title：Pediatric pulmonology

authors： Al-Khalidi FQ,Saatchi R,Burke D,Elphick H,Tan S

更新日期：2011-06-01 00:00:00

abstract：:Bronchopulmonary dysplasia (BPD) is a chronic obstructive pulmonary disease of prematurely born infants following prolonged mechanical ventilation and oxygen therapy. Developmental changes in pulmonary function of children with BPD during their early years have been difficult to study. We longitudinally studied maxima...

journal_title：Pediatric pulmonology

authors： Mallory GB Jr,Chaney H,Mutich RL,Motoyama EK

更新日期：1991-01-01 00:00:00

abstract：INTRODUCTION:There are few published data on the efficacy of systemic corticosteroids in preterm infants with very severe forms of bronchopulmonary dysplasia (BPD), requiring respiratory support after 3 months of age. The aim of this study was to report the use of pulses of methylprednisolone in this population and its...

journal_title：Pediatric pulmonology

authors： Billion E,Hadchouel A,Garcelon N,Delacourt C,Drummond D

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND:The measurement of specific airway resistance during tidal breathing (sRaw(tb)) has gained popularity in children, but methodological concerns have been raised regarding the electronic compensation for the thermal artifact. The panting method (sRaw(p)) is efficient in minimizing the latter, but may be associ...

journal_title：Pediatric pulmonology

authors： Coutier L,Varechova S,Demoulin B,Bonabel C,Roman-Amat C,Tuan TL,Ioan I,Schweitzer C,Marchal F

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:There is currently no evidence-based method for defining competency in pediatric flexible bronchoscopy (FB). Based on expert opinion, guidelines using numbers of procedures have been published in defining competency for pediatric FB. The purpose of this study was to formally survey the opinion of USA pediatri...

journal_title：Pediatric pulmonology

authors： Leong AB,Green CG,Kurland G,Wood RE

更新日期：2014-06-01 00:00:00

abstract：AIM:To analyze breathing pattern and mechanical ventilatory constraints during incremental exercise in healthy and cystic fibrosis (CF) children. METHODS:Thirteen healthy children and 6 children with cystic fibrosis volunteered to perform an incremental test on a treadmill. Exercise tidal flow/volume loops were plotte...

journal_title：Pediatric pulmonology

authors： Borel B,Leclair E,Thevenet D,Beghin L,Gottrand F,Fabre C

更新日期：2014-03-01 00:00:00

abstract：:There is currently no validated scoring system for quantification of airway secretions in children. A user friendly, valid scoring system of airway secretions during flexible bronchoscopy (FB) would be useful for comparative purposes in clinical medicine and research. The objective of this study was to validate our br...

journal_title：Pediatric pulmonology

authors： Chang AB,Faoagali J,Cox NC,Marchant JM,Dean B,Petsky HL,Masters IB

更新日期：2006-09-01 00:00:00

abstract：RATIONALE:Nitric oxide (NO) produced in the lung is an important mediator of normal lung development, vascular smooth muscle relaxation, and ventilation perfusion matching. NO is synthesized from arginine by the action of NO-synthase (NOS). Asymmetric dimethylarginine (ADMA), an endogenous derivate of arginine, inhibit...

journal_title：Pediatric pulmonology

authors： Richir MC,van Leeuwen PA,van den Berg A,Wessels R,Twisk JW,Rauwerda JA,Teerlink T,de Vries TP,van Elburg RM

更新日期：2008-12-01 00:00:00

abstract：:Pulmonary hemorrhage (PH) is a serious complication causing acute respiratory distress in the premature infant, and it is associated with significant mortality and morbidity. The role of inflammatory mediators in this condition is largely undefined. Serial tracheal aspirates (TA) were obtained at intervals from 65 mec...

journal_title：Pediatric pulmonology

authors： Baier RJ,Loggins J,Kruger TE

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound with an echobronchoscope-guided fine needle aspiration (EUS-B-FNA) are useful modalities in the evaluation of mediastinal pathologies in adults. However, sparse data are available in children. OBJECTIVE:To...

journal_title：Pediatric pulmonology

authors： Gulla KM,Gunathilaka G,Jat KR,Sankar J,Karan M,Lodha R,Kabra SK

更新日期：2019-06-01 00:00:00

abstract：:Tracheal bronchus (TRB) has been generally considered an anatomical variant of the tracheobronchial tree without a precise pathological effect. Its prevalence is estimated to be between 0.2% to 3% of all children undergoing bronchoscopy and scientific information has been limited to case reports or small case series. ...

journal_title：Pediatric pulmonology

authors： Moreno M,Castillo-Corullón S,Pérez-Ruiz E,Luna MC,Antón-Pacheco JL,Mondejar-Lopez P,De-la-Serna O,Villa JR,Osona B,Torres-Borrego J,Santiago-Burruchaga M,Asensio O,Andres-Martin A,Delgado-Pecellin I,González Y,Palmero A,E

更新日期：2019-10-01 00:00:00

abstract：BACKGROUND:sTREM-1 (soluble triggering receptor expressed on myeloid cells-1) is a novel inflammatory marker that may be of clinical use in cystic fibrosis (CF). Dysregulation of the TREM pathway has been demonstrated in other inflammatory diseases and modulation in animal models has therapeutic benefit. We hypothesise...

journal_title：Pediatric pulmonology

authors： Forrester DL,Barr HL,Fogarty A,Knox A

更新日期：2017-04-01 00:00:00

abstract：:Most pneumatoceles disappear spontaneously and do not cause severe symptoms. Treatment alternatives include various conventional or surgical methods. However, an enlarging, complicated pneumatocele with cardiorespiratory instability requires imaging-guided catheter drainage or surgery. Here, we report the case of a ne...

journal_title：Pediatric pulmonology

authors： Park TH,Kim JK

更新日期：2016-02-01 00:00:00

abstract：:Our objective was to determine the repeatability of bronchial responsiveness to mannitol dry powder (MDP) as an objective marker of asthma in children. MDP challenge was performed in children with stable asthma at the same time of the day on two separate occasions within a week. The test was terminated after a 15% fal...

journal_title：Pediatric pulmonology

authors： Barben J,Roberts M,Chew N,Carlin JB,Robertson CF

更新日期：2003-12-01 00:00:00

abstract：INTRODUCTION:Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders characterized by tissue deposition of glycosaminoglycans (GAG). Their musculoskeletal abnormalities and the GAG storage in the airway result in increased risk for patients undergoing anesthesia. This study evaluates a multi-disciplinary...

journal_title：Pediatric pulmonology

authors： Muhlebach MS,Shaffer CB,Georges L,Abode K,Muenzer J

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Ivacaftor is a significant innovation in the treatment of cystic fibrosis (CF) with gating mutations. A substantial percentage of patients with CF have severe lung involvement, but these patients are usually excluded from phase III clinical trials. Thus, the effectiveness of ivacaftor in this population has ...

journal_title：Pediatric pulmonology

authors： Salvatore D,Carnovale V,Iacotucci P,Braggion C,Castellani C,Cimino G,Colangelo C,Francalanci M,Leonetti G,Lucidi V,Manca A,Vitullo P,Ferrara N

更新日期：2019-09-01 00:00:00

abstract：:Multiple breath inert gas washout (MBW) is gaining popularity for measurements of resting lung volume and ventilation inhomogeneity. Test reproducibility is an important determinant of the clinical applicability of diagnostic tests. The between-test reproducibility of variables derived from MBW tests in newborn infant...

journal_title：Pediatric pulmonology

authors： Sinhal S,Galati J,Baldwin DN,Stocks J,Pillow JJ

更新日期：2010-01-01 00:00:00

abstract：BACKGROUND:Patient-reported outcomes (PROs) are increasingly used to evaluate the efficacy of new treatments and the progression of chronic diseases. The Cystic Fibrosis Questionnaire-Revised (CFQ-R) is a disease-specific, PRO measure of health-related quality of life (HRQOL). We evaluated associations between changes ...

journal_title：Pediatric pulmonology

authors： Sawicki GS,Rasouliyan L,McMullen AH,Wagener JS,McColley SA,Pasta DJ,Quittner AL

更新日期：2011-01-01 00:00:00