Intravenous pulses of methylprednisolone for infants with severe bronchopulmonary dysplasia and respiratory support after 3 months of age.

abstract：:Neurally adjusted ventilatory assistance (NAVA) can overcome technical difficulties with synchronizing noninvasive ventilation breaths with the patient, a modality often used in very low birthweight infants (VLBW) with apnea of prematurity (AOP). This study is a retrospective single-center investigation into whether N...

journal_title：Pediatric pulmonology

authors： Tabacaru CR,Moores RR Jr,Khoury J,Rozycki HJ

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVES:Forced expiratory volume in 1 second (FEV1) is an important predictor of outcome in cystic fibrosis (CF). This study aimed to describe the change in lung function, nutritional status, and mortality of children with CF at a single center in Cape Town, South Africa, and identify factors associated with poor lu...

journal_title：Pediatric pulmonology

authors： Vandenbroucke NJ,Zampoli M,Morrow B

更新日期：2020-06-01 00:00:00

abstract：BACKGROUND:Gastro-esophageal reflux (GOR) may contribute to lung disease in children with cystic fibrosis (CF). There is conflicting evidence regarding the effect of chest physiotherapy (CPT) in the head-down position on GOR. Furthermore, there is currently no evidence on the impact of physiotherapy on GOR as assessed ...

journal_title：Pediatric pulmonology

authors： Doumit M,Krishnan U,Jaffé A,Belessis Y

更新日期：2012-02-01 00:00:00

abstract：:The long-term efficacy and safety of aminoglycoside aerosol therapy for Pseudomonas aeruginosa colonization/infection in cystic fibrosis has not been fully investigated. In the present study, 14 patients with cystic fibrosis, ages 8-19 years (mean: 13.3 years), received tobramycin aerosol therapy for a mean duration o...

journal_title：Pediatric pulmonology

authors： Steinkamp G,Tümmler B,Gappa M,Albus A,Potel J,Döring G,von der Hardt H

更新日期：1989-01-01 00:00:00

abstract：:Spontaneous hemopneumothorax (SHP) is a rare potentially life-threatening condition that occurs in predominantly young adolescents. The resultant massive hemorrhage leading to hypovolemic shock can be a surgical emergency. It constitutes 1-12% of all spontaneous pneumothoraces and presents with two cardinal features, ...

journal_title：Pediatric pulmonology

authors： Chen TH,Tseng YH,Tseng CM,Chiang HH,Lin TJ

更新日期：2014-01-01 00:00:00

abstract：AIM:Our aim was to evaluate the correlation of Adenosine monophosphate challenge test (AMP-PCW) results with the patients' subsequent clinical course. METHODS:We performed a 6-year retrospective cohort study of young children with suspected asthma who underwent AMP-PCW test. RESULTS:Fifty four children were included ...

journal_title：Pediatric pulmonology

authors： Levin G,Rottensctreich A,Picard E,Avital A,Springer C,Cohen S

更新日期：2019-07-01 00:00:00

abstract：:Pneumatoceles and bronchiectasis are secondary complications of respiratory infections in patients with hyper IgE syndrome (HIgES). We report on a patient with HIgES and recurrent pneumonias since 1 year of age, with progression to pneumatoceles and bronchiectasis and fatal outcome, with disseminated infection and sus...

journal_title：Pediatric pulmonology

authors： Roxo P Jr,Torres LA,Menezes UP,Melo JM

更新日期：2013-01-01 00:00:00

abstract：:Twenty patients with cystic fibrosis (CF) were trained to mobilize intrabronchial secretions by a new method of positive expiratory pressure mask (PEP mask) physiotherapy (PT). Patients repeatedly expired forcefully through the PEP mask; expiratory resistance was varied by eight different internal diameter resistors a...

journal_title：Pediatric pulmonology

authors： Oberwaldner B,Evans JC,Zach MS

更新日期：1986-11-01 00:00:00

abstract：OBJECTIVE:Since preventive therapies for bronchopulmonary dysplasia (BPD) are limited we treated preterm infants with azithromycin to decrease the incidence of BPD. METHODS:Infants less than 1,250 g birth weight were randomized to azithromycin or placebo within 12 hr of beginning mechanical ventilation and within 72 h...

journal_title：Pediatric pulmonology

authors： Ballard HO,Shook LA,Bernard P,Anstead MI,Kuhn R,Whitehead V,Grider D,Crawford TN,Hayes D Jr

更新日期：2011-02-01 00:00:00

abstract：:We assessed the ability of innovative lung function tests to detect bronchial obstruction induced by methacholine bronchial challenge. Fifty-five recurrently wheezy infants (mean age 16 +/- 5.2 months) free of respiratory symptoms underwent baseline lung function tests. Forty-two completed the methacholine challenge. ...

journal_title：Pediatric pulmonology

authors： Benoist MR,Brouard JJ,Rufin P,Delacourt C,Waernessyckle S,Scheinmann P

更新日期：1994-11-01 00:00:00

abstract：:Bronchiolitis in infancy is a risk factor for development of asthma in the first decades of life, although the majority may be asymptomatic at school age. Respiratory symptoms are common in early life, and prediction of later asthma may be challenging. We aimed to study if simple clinical variables assessed at 2 years...

journal_title：Pediatric pulmonology

authors： Mikalsen IB,Halvorsen T,Eide GE,Øymar K

更新日期：2013-06-01 00:00:00

abstract：:The jet nebulizer is a common device used for administering aerosol medication in young children. However, compared to a metered dose inhaler-spacer (MDI-spacer), it takes more time and personnel. This study aimed to compare the efficacy of salbutamol aerosol therapy given via these two devices in young wheezing child...

journal_title：Pediatric pulmonology

authors： Deerojanawong J,Manuyakorn W,Prapphal N,Harnruthakorn C,Sritippayawan S,Samransamruajkit R

更新日期：2005-05-01 00:00:00

abstract：:This review summarizes current knowledge about the role of nitric oxide (NO) in cystic fibrosis (CF) lung disease. NO is endogenously produced by a group of enzymes, the NO synthases (NOSs). There are three isoforms of NOS, each encoded by different genes: neuronal (nNOS), immune or inducible (iNOS), and endothelial (...

journal_title：Pediatric pulmonology

authors： Grasemann H,Ratjen F

更新日期：1999-12-01 00:00:00

abstract：:For the last thirty years, oral chloral hydrate has been used for sedation of infants for lung function testing. Recently, however, availability of chloral hydrate became severely limited in the United States after two manufacturers discontinued manufacturing in 2012. Due to these limitations and the recent and ongoin...

journal_title：Pediatric pulmonology

authors： Callahan P,Pinto SJ,Kurland G,Cain JG,Motoyama EK,Weiner DJ

更新日期：2015-02-01 00:00:00

abstract：INTRODUCTION:Mucopolysaccharidoses (MPS) are a group of lysosomal storage disorders characterized by tissue deposition of glycosaminoglycans (GAG). Their musculoskeletal abnormalities and the GAG storage in the airway result in increased risk for patients undergoing anesthesia. This study evaluates a multi-disciplinary...

journal_title：Pediatric pulmonology

authors： Muhlebach MS,Shaffer CB,Georges L,Abode K,Muenzer J

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Ivacaftor is a significant innovation in the treatment of cystic fibrosis (CF) with gating mutations. A substantial percentage of patients with CF have severe lung involvement, but these patients are usually excluded from phase III clinical trials. Thus, the effectiveness of ivacaftor in this population has ...

journal_title：Pediatric pulmonology

authors： Salvatore D,Carnovale V,Iacotucci P,Braggion C,Castellani C,Cimino G,Colangelo C,Francalanci M,Leonetti G,Lucidi V,Manca A,Vitullo P,Ferrara N

更新日期：2019-09-01 00:00:00

abstract：OBJECTIVE:To determine if fetal growth restriction (FGR) in the setting of sterile intra-uterine milieu would be associated with a decrease in respiratory distress syndrome (RDS) of preterm-neonates. METHODS:The relationship between FGR and neonatal RDS was examined in 92 singleton preterm-neonates (gestational age [G...

journal_title：Pediatric pulmonology

authors： Park CW,Park JS,Jun JK,Yoon BH

更新日期：2016-08-01 00:00:00

abstract：:Multiresistance in Stenotrophomonas maltophilia limits the effectiveness of antimicrobial therapy for infections due to this organism. It can be of special concern in cystic fibrosis (CF) patients due to frequent antimicrobial administration. The in vitro activity of 41 antimicrobial agents against 76 epidemiologicall...

journal_title：Pediatric pulmonology

authors： Cantón R,Valdezate S,Vindel A,Sánchez Del Saz B,Maíz L,Baquero F

更新日期：2003-02-01 00:00:00

abstract：:Spirometric testing is traditionally achievable in children of school-age and beyond. Incorporation of interactive incentives motivates preschool children to facilitate measurement of forced expiratory indices. Validated spirometric reference standards are available for Caucasian preschoolers but lacking in Asians. We...

journal_title：Pediatric pulmonology

authors： Leung TF,Liu TC,Mak KK,Su X,Sy HY,Li AM,Lau JT,Lum S,Wong GW

更新日期：2013-11-01 00:00:00

abstract：:The incidence of empyema complicating community-acquired pneumonia is increasing and causes significant childhood morbidity. Pneumococcal infection remains the most common isolated cause in developed countries, with Staphylococcus aureus the predominant pathogen in the developing world. Newer molecular techniques util...

journal_title：Pediatric pulmonology

authors： Jaffé A,Balfour-Lynn IM

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND:Accelerated lung function decline in cystic fibrosis (CF) is associated with mucoid Pseudomonas aeruginosa infection. Recent data suggest that mucoid P. aeruginosa may amenable to elimination from the airway. We aim to determine whether the initiation of an aggressive antibiotic eradication regimen upon init...

journal_title：Pediatric pulmonology

authors： Troxler RB,Hoover WC,Britton LJ,Gerwin AM,Rowe SM

更新日期：2012-11-01 00:00:00

abstract：:Pulmonary sequestration is a rare anomaly and is conventionally treated with surgical excision. This report describes the successful occlusion of a large aberrant artery to an intralobar pulmonary sequestration using an Amplatzer Vascular Plug. ...

journal_title：Pediatric pulmonology

authors： Hwang HK,Tsai YS,Lin SM,Chen MR

更新日期：2008-09-01 00:00:00

abstract：INTRODUCTION:In this cohort study spanning an 18-year period, we evaluated the prevalence and associated mortality rate of epidemic strains of pseudomonas aeruginosa (PsA), especially Australian Epidemic Strain Type 1 (AES1), in a pediatric cystic fibrosis center practicing cohort segregation and early PsA eradication....

journal_title：Pediatric pulmonology

authors： Kevat A,Carzino R,Massie J,Harrison J,Griffiths AL

更新日期：2018-11-01 00:00:00

abstract：:The airway epithelium represents a primary site for the introduction and deposition of potentially pathogenic microorganisms into the body, through inspired air. The epithelial mucosa is an important component of the innate immune system that recognizes conserved structures in microorganisms and initiates appropriate ...

journal_title：Pediatric pulmonology

authors： Gómez MI,Prince A

更新日期：2008-01-01 00:00:00

abstract：:Deficiency of mannose-binding lectin has been shown to be a risk factor for cystic fibrosis (CF) patients. We, therefore, decided to treat a patient with CF, mannose-binding lectin deficiency, severe bronchopulmonary Pseudomonas aeruginosa infection, and rapid deterioration of lung function with purified mannose-bindi...

journal_title：Pediatric pulmonology

authors： Garred P,Pressler T,Lanng S,Madsen HO,Moser C,Laursen I,Balstrup F,Koch C,Koch C

更新日期：2002-03-01 00:00:00

abstract：:Although airway obstruction and chronic endobronchial infection have long been recognized as major factors in the pathogenesis of lung disease in cystic fibrosis (CF), only recently has it been recognized that the inflammatory process itself may be responsible in a major way for destroying the lungs. The most characte...

journal_title：Pediatric pulmonology

authors： Konstan MW,Berger M

更新日期：1997-08-01 00:00:00

abstract：OBJECTIVES:We sought to compare gas exchange, respiratory mechanics, and asynchronies during pressure support ventilation (PSV), sigh adjunct to PSV (PSV SIGH), and neurally adjusted ventilatory assist (NAVA) in hypoxemic infants after cardiac surgery. DESIGN:Prospective, single-center, crossover, randomized physiolog...

journal_title：Pediatric pulmonology

authors： Bonacina D,Bronco A,Nacoti M,Ferrari F,Fazzi F,Bonanomi E,Bellani G

更新日期：2019-07-01 00:00:00

abstract：RATIONALE:Nitric oxide (NO) produced in the lung is an important mediator of normal lung development, vascular smooth muscle relaxation, and ventilation perfusion matching. NO is synthesized from arginine by the action of NO-synthase (NOS). Asymmetric dimethylarginine (ADMA), an endogenous derivate of arginine, inhibit...

journal_title：Pediatric pulmonology

authors： Richir MC,van Leeuwen PA,van den Berg A,Wessels R,Twisk JW,Rauwerda JA,Teerlink T,de Vries TP,van Elburg RM

更新日期：2008-12-01 00:00:00

abstract：:Pediatric lung transplantation has advanced over the years, providing a potential life-prolonging therapy to patients with cystic fibrosis. Despite this, many challenges in lung transplantation remain and result in worse outcomes than other solid organ transplants. As CF lung disease progresses, children and their car...

journal_title：Pediatric pulmonology

authors： Dellon E,Goldfarb SB,Hayes D Jr,Sawicki GS,Wolfe J,Boyer D

更新日期：2017-11-01 00:00:00

abstract：OBJECTIVE:There is currently no evidence-based method for defining competency in pediatric flexible bronchoscopy (FB). Based on expert opinion, guidelines using numbers of procedures have been published in defining competency for pediatric FB. The purpose of this study was to formally survey the opinion of USA pediatri...

journal_title：Pediatric pulmonology

authors： Leong AB,Green CG,Kurland G,Wood RE

更新日期：2014-06-01 00:00:00