Mannose-binding lectin (MBL) therapy in an MBL-deficient patient with severe cystic fibrosis lung disease.

abstract：:The tidal flow volume (TFV) loop ratios of (1) time to peak flow (tPTEF) to total expiratory time (tE) [tPTEF/tE] and (2) volume to peak flow (VPTEF) to expired volume (VE) [VPTEF/VE] are reported to decrease with age in early life, and to decrease in subjects with obstructive airways disease (OAD). However, the mecha...

journal_title：Pediatric pulmonology

authors： Lødrup Carlsen KC,Stenzler A,Carlsen KH

更新日期：1997-12-01 00:00:00

abstract：:We reviewed the literature on the effects of high flow nasal cannula (HFNC) and heated, humidified, high-flow, nasal cannula (HHHFNC) treatment in preterm infants. We found nine studies, but only two were randomized controlled trials. These studies show that: HFNC application is associated to the delivery of continuou...

journal_title：Pediatric pulmonology

authors： Dani C,Pratesi S,Migliori C,Bertini G

更新日期：2009-07-01 00:00:00

abstract：BACKGROUND:Patients with bronchopulmonary dysplasia (BPD) may require tracheostomy for long-term mechanical ventilation. Polysomnography (PSG) may predict successful decannulation in children, however it is unclear how this success compares with children without a PSG. To better evaluate this role, we compared decannul...

journal_title：Pediatric pulmonology

authors： Quinlan C,Piccione J,Kim JY,Beck SE,Brooks L,Chandy-Patel R,Escobar E,Afolabi-Brown O

更新日期：2019-11-01 00:00:00

abstract：:A 16-year-old female with cystic fibrosis (CF) presented with an acute respiratory exacerbation during which black flecks were observed in the spontaneously expectorated sputum. The production of this pigmented sputum was subsequently attributed to Exophiala dermatitidis hyphae. Treatment with antibiotics, corticoster...

journal_title：Pediatric pulmonology

authors： Griffard EA,Guajardo JR,Cooperstock MS,Scoville CL

更新日期：2010-05-01 00:00:00

abstract：:Our objective was to study meconium-induced lung injury in isolated perfused rat lungs exposed to anoxia. Our working hypothesis was that meconium-induced lung injury is independent of preexisting hypoxia, and that hypoxia will increase severity of lung injury observed after meconium aspiration. We compared five diffe...

journal_title：Pediatric pulmonology

authors： Wisniewski WM,Zagariya AM,Pavuluri N,Srinivasan H,Shankarao S,Vidyasagar D

更新日期：2005-04-01 00:00:00

abstract：:The collection of sputum for microbiological examination in young cystic fibrosis patients can be very difficult. However, a knowledge of bacterial flora colonizing the patient's airways is of paramount importance for proper antimicrobial therapy. It is also known that cystic fibrosis patients colonized by Pseudomonas...

journal_title：Pediatric pulmonology

authors： Vogelberg C,Hirsch T,Rösen-Wolff A,Kerkmann ML,Leupold W

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:Telomere length is associated with poorer lung health in older adults, possibly from cumulative risk factor exposure, but data are lacking in pediatric and population-based cohorts. We examined associations of telomere length with lung function in children and mid-life adults. METHODS:Data were drawn from a ...

journal_title：Pediatric pulmonology

authors： Nguyen MT,Saffery R,Burgner D,Lycett K,Vryer R,Grobler A,Dwyer T,Ranganathan S,Wake M

更新日期：2019-12-01 00:00:00

abstract：:In this article, we describe existing CF registries with a focus on US registry data collected through the CF Foundation Patient Registry (CFFPR) and the Epidemiologic Study of CF (ESCF); highlight what registries have taught us regarding epidemiology of CF; showcase the impact of registries on research and clinical c...

journal_title：Pediatric pulmonology

authors： Fink AK,Loeffler DR,Marshall BC,Goss CH,Morgan WJ

更新日期：2017-11-01 00:00:00

abstract：BACKGROUND:Treatment regimens for patients with cystic fibrosis (CF) are time-consuming and complex, resulting in consistently low adherence rates. To date, few studies have evaluated innovative technologies to improve adherence in this population. Current infection control guidelines for patients with CF seek to minim...

journal_title：Pediatric pulmonology

authors： Marciel KK,Saiman L,Quittell LM,Dawkins K,Quittner AL

更新日期：2010-02-01 00:00:00

abstract：:Short-acting β2-adrenergic receptor agonists are commonly used bronchodilators for symptom relief in asthmatics. Recent evidence demonstrated that prolonged exposure of cultured airway smooth muscle cells to β2 agonists directly augments procontractile signaling pathways with the change in expression of regulator of G...

journal_title：Pediatric pulmonology

authors： Labuda M,Laberge S,Brière J,Bérubé D,Krajinovic M

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Magnetic Resonance Imaging (MRI) techniques to image the larynx have evolved rapidly into a promising and safe imaging modality, without need for sedation or ionizing radiation. MRI is therefore of great interest to image pediatric laryngeal diseases. Our aim was to review MRI developments relevant for the p...

journal_title：Pediatric pulmonology

authors： Elders BBLJ,Hermelijn SM,Tiddens HAWM,Pullens B,Wielopolski PA,Ciet P

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Pressure rise time (PRT), also known as slope time to the peak inflating pressure can be set on some modern neonatal ventilators. On other ventilators, PRT is determined by the set circuit flow. Changing slope time can affect mean airway pressure (MAP), oxygenation, and carbon dioxide elimination. Our aim wa...

journal_title：Pediatric pulmonology

authors： Chong D,Kayser S,Szakmar E,Morley CJ,Belteki G

更新日期：2020-05-01 00:00:00

abstract：:Two hundred twenty-six healthy school children, with a mean age of 8.8 years; 62 girls mean age 8.8, 48 boys mean age 12.6 and 51 girls mean age 12.6 years at the start, were enrolled in a longitudinal study of lung function and tested annually for 5 years. All were free of respiratory symptoms, and none smoked more t...

journal_title：Pediatric pulmonology

authors： Hibbert ME,Hudson IL,Lanigan A,Landau LI,Phelan PD

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Pneumonia is a leading killer of children under-5 years, with a high burden in Nigeria. We aimed to quantify the regional burden and risks of pediatric pneumonia in Nigeria, and specifically the states of Lagos and Jigawa. METHODS:We conducted a scoping literature search for studies of pneumonia morbidity a...

journal_title：Pediatric pulmonology

authors： Iuliano A,Aranda Z,Colbourn T,Agwai IC,Bahiru S,Bakare AA,Burgess RA,Cassar C,Shittu F,Graham H,Isah A,McCollum ED,Falade AG,King C,On Behalf Of The Inspiring Project Consortium

更新日期：2020-06-01 00:00:00

abstract：:Background The prevalence of respiratory-technology dependent children is increasing although for most children the goal is liberation from technology. Liberation from home mechanical ventilation (HMV) and decannulation strategies vary due to the lack of clinical practice standards. The primary objective of this study...

journal_title：Pediatric pulmonology

authors： Bashir A,Henningfeld JK,Thompson NE,D'Andrea LA

更新日期：2018-11-01 00:00:00

abstract：BACKGROUND:Quantifying the chest wall is useful in documenting thoracoabdominal synchrony during the neonatal period. Subjective measures are often used rather than gold-standard methods due to their practicality in clinical practice. The aim of the present study is to compare the reliability between a newly proposed m...

journal_title：Pediatric pulmonology

authors： Gomes DC,Azevedo IG,de Figueiredo Araújo AG,da Costa Lopes LD,Nagem DAP,Magalhães FA,Pereira SA

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:Night-time symptoms and hypoxemia during sleep may affect sleep quality in children with chronic lung disease such as bronchiectasis. Poor sleep quality may impair growth, learning, and emotional development of children. Our aim was to assess the sleep quality and associated factors in children with non-cyst...

journal_title：Pediatric pulmonology

authors： Erdem E,Ersu R,Karadag B,Karakoc F,Gokdemir Y,Ay P,Akpinar IN,Dagli E

更新日期：2011-09-01 00:00:00

abstract：OBJECTIVE:Both healthy preterm infants and those with bronchopulmonary dysplasia (BPD) have poor lung function during childhood and adolescence, although there is no evidence whether prematurity alone explains the reduction in lung function found in BPD infants. Our study seeks to know if lung function, measured in inf...

journal_title：Pediatric pulmonology

authors： Sanchez-Solis M,Garcia-Marcos L,Bosch-Gimenez V,Pérez-Fernandez V,Pastor-Vivero MD,Mondéjar-Lopez P

更新日期：2012-07-01 00:00:00

abstract：OBJECTIVE:Lung ultrasound (LUS) is an emerging tool that may be used in the diagnosis and follow-up of children with viral bronchiolitis. In this study, we describe LUS abnormalities in children receiving invasive mechanical ventilation (IMV) for severe bronchiolitis in the pediatric intensive care unit (PICU). Our aim...

journal_title：Pediatric pulmonology

authors： Ingelse SA,Pisani L,Westdorp MHA,Almakdase M,Schultz MJ,van Woensel JBM,Bem RA

更新日期：2020-10-01 00:00:00

abstract：:In adults, the term specific pulmonary renal syndrome describes disorders with pulmonary and glomerular manifestations and includes Wegener's granulomatosis, Goodpasture disease, and systemic lupus erythematosus. Nonspecific pulmonary renal syndrome refers to either pulmonary disease complicating glomerular disease, o...

journal_title：Pediatric pulmonology

authors： von Vigier RO,Trummler SA,Laux-End R,Sauvain MJ,Truttmann AC,Bianchetti MG

更新日期：2000-05-01 00:00:00

abstract：:Pneumatoceles and bronchiectasis are secondary complications of respiratory infections in patients with hyper IgE syndrome (HIgES). We report on a patient with HIgES and recurrent pneumonias since 1 year of age, with progression to pneumatoceles and bronchiectasis and fatal outcome, with disseminated infection and sus...

journal_title：Pediatric pulmonology

authors： Roxo P Jr,Torres LA,Menezes UP,Melo JM

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:In 1995 the Tucson Children's Respiratory Study (TCRS) identified clinically distinct phenotypes amongst early wheezers; the Avon Longitudinal Study of Parents And Children (ALSPAC) has recently re-examined these. OBJECTIVES:To validate statistically derived ALSPAC phenotypes in the Southampton Women's Surv...

journal_title：Pediatric pulmonology

authors： Collins SA,Pike KC,Inskip HM,Godfrey KM,Roberts G,Holloway JW,Lucas JS,Southampton Women's Survey Study Group.

更新日期：2013-07-01 00:00:00

abstract：:We assessed the ability of innovative lung function tests to detect bronchial obstruction induced by methacholine bronchial challenge. Fifty-five recurrently wheezy infants (mean age 16 +/- 5.2 months) free of respiratory symptoms underwent baseline lung function tests. Forty-two completed the methacholine challenge. ...

journal_title：Pediatric pulmonology

authors： Benoist MR,Brouard JJ,Rufin P,Delacourt C,Waernessyckle S,Scheinmann P

更新日期：1994-11-01 00:00:00

abstract：:We enrolled 30 infants (median age 3 months, range 1-12 months), hospitalized for bronchiolitis in a randomized double-blind trial, to examine the efficacy and safety of nebulized epinephrine compared to salbutamol. Once admitted, patients were treated with either nebulized 0.5 mg of an 0.1% epinephrine solution (0.5 ...

journal_title：Pediatric pulmonology

authors： Bertrand P,Araníbar H,Castro E,Sánchez I

更新日期：2001-04-01 00:00:00

abstract：BACKGROUND:Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) and endoscopic ultrasound with an echobronchoscope-guided fine needle aspiration (EUS-B-FNA) are useful modalities in the evaluation of mediastinal pathologies in adults. However, sparse data are available in children. OBJECTIVE:To...

journal_title：Pediatric pulmonology

authors： Gulla KM,Gunathilaka G,Jat KR,Sankar J,Karan M,Lodha R,Kabra SK

更新日期：2019-06-01 00:00:00

abstract：OBJECTIVE:To determine if fetal growth restriction (FGR) in the setting of sterile intra-uterine milieu would be associated with a decrease in respiratory distress syndrome (RDS) of preterm-neonates. METHODS:The relationship between FGR and neonatal RDS was examined in 92 singleton preterm-neonates (gestational age [G...

journal_title：Pediatric pulmonology

authors： Park CW,Park JS,Jun JK,Yoon BH

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Chest computerized tomography (CT) scores are associated with the frequency of future pulmonary exacerbations in people with cystic fibrosis (CF). However, cut-off values to identify children with mild lung disease with different risks for frequent future pulmonary exacerbations have not been identified. ME...

journal_title：Pediatric pulmonology

authors： Sanders DB,Li Z,Parker-McGill K,Farrell P,Brody AS

更新日期：2018-10-01 00:00:00

abstract：UNLABELLED:SUMMARY RATIONALE: Asthma therapy should be stepped up or stepped down in response to changes in asthma control. However, there is little evidence available on the optimal timing, sequence, and degree of medication reductions. In this study we analyzed clinically stable asthmatic children who underwent a med...

journal_title：Pediatric pulmonology

authors： Kersten ET,Driessen JM,van Leeuwen JC,Thio BJ

更新日期：2010-09-01 00:00:00

abstract：OBJECTIVE:Medication adherence among adolescents with cystic fibrosis (CF) is often suboptimal and this has significant impact on their health and quality of life. The purpose of the study was to evaluate the impact of frequent home pulmonary function (PFT) monitoring on medication adherence among adolescents with CF. ...

journal_title：Pediatric pulmonology

authors： Shakkottai A,Kaciroti N,Kasmikha L,Nasr SZ

更新日期：2018-04-01 00:00:00

abstract：:Tracheal bronchus (TRB) has been generally considered an anatomical variant of the tracheobronchial tree without a precise pathological effect. Its prevalence is estimated to be between 0.2% to 3% of all children undergoing bronchoscopy and scientific information has been limited to case reports or small case series. ...

journal_title：Pediatric pulmonology

authors： Moreno M,Castillo-Corullón S,Pérez-Ruiz E,Luna MC,Antón-Pacheco JL,Mondejar-Lopez P,De-la-Serna O,Villa JR,Osona B,Torres-Borrego J,Santiago-Burruchaga M,Asensio O,Andres-Martin A,Delgado-Pecellin I,González Y,Palmero A,E

更新日期：2019-10-01 00:00:00