Prenatal exposure to VOCs and NOx and lung function in preschoolers.

Abstract:

BACKGROUND:Several studies have shown that exposure to air pollutants affects lung growth and development and can result in poor respiratory health in early life. METHODS:We included a subsample of 772 Mexican preschoolers whose mothers participated in a Prenatal Omega-3 fatty acid Supplements, GRowth, And Development birth cohort study with the aim to evaluate the impact of prenatal exposure to volatile organic compounds and nitrogen oxides on lung function measured by oscillation tests. The preschoolers were followed until 5 years of age. Anthropometric measurements and forced oscillation tests were performed at 36, 48, and 60 months of age. Information on sociodemographic and health characteristics was obtained during follow up. Prenatal exposure to volatile organic compounds and nitrogen oxides was evaluated using a land use regression models and the association between them was tested using a lineal regression and longitudinal linear mixed effect models adjusting for potential confounders. RESULTS:Overall, the mean (standard deviation) of the measurements of respiratory system resistance and respiratory system reactance at 6, 8, and 10 Hz during the follow-up period was 11.3 (2.4), 11.1 (2.4), 10.3 (2.2) and -5.2 (1.6), -4.8 (1.7), and -4.6 hPa s L-1 (1.6), respectively. We found a significantly positive association between respiratory resistance (βRrs6  = 0.011; 95%CI: 0.001, 0.023) (P < .05) and prenatal exposure to nitrogen dioxide and a marginally negatively association between respiratory reactance (βXrs6  = -11.40 95%CI: -25.26, 1.17 and βXrs8  = -11.91 95%CI: -26.51, 1.43) (P = .07) and prenatal exposure to xylene. CONCLUSION:Prenatal exposure to air pollutants was significantly associated with the alteration of lung function measured by oscillation tests in these preschool children.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Gutiérrez-Delgado RI,Barraza-Villarreal A,Escamilla-Núñez MC,Hernández-Cadena L,Cortez-Lugo M,Sly P,Romieu I

doi

10.1002/ppul.24889

subject

Has Abstract

pub_date

2020-08-01 00:00:00

pages

2142-2149

issue

8

eissn

8755-6863

issn

1099-0496

journal_volume

55

pub_type

杂志文章
  • Predictors of proper inhaler technique and asthma control in pediatric patients with asthma.

    abstract:BACKGROUND:Improper use of asthma inhalers is one of the potential factors of poor asthma control among children. This study aimed to assess the proper handling of asthma inhalers and asthma control in addition to factors influencing them among pediatric patients who self-administer their inhalers. METHODS:A cross-sec...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.25263

    authors: Almomani BA,Al-Qawasmeh BS,Al-Shatnawi SF,Awad S,Alzoubi SA

    更新日期:2021-01-26 00:00:00

  • Ventilation homogeneity improves with growth early in life.

    abstract::Some studies have suggested that lung clearance index (LCI) is age-independent among healthy subjects early in life, which implies that ventilation distribution does not vary with growth. However, other studies of older children and adolescents suggest that ventilation becomes more homogenous with somatic growth. We d...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21553

    authors: Chakr VC,Llapur CJ,Sarria EE,Mattiello R,Kisling J,Tiller C,Kimmel R,Poindexter B,Tepper RS

    更新日期:2012-04-01 00:00:00

  • Is aspiration during swallowing more common in Canadian children with indigenous heritage?

    abstract::While many factors that contribute to the occurrence of lower respiratory tract infections (LRTI) in Canadian indigenous children have been described, the role of aspiration during swallowing has not been explored in these children. Because of an increase in referrals of indigenous children from our catchment area (Ma...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21489

    authors: Rempel G,Borton B,Esselmont E,Shelton C

    更新日期:2011-12-01 00:00:00

  • Risk factors for fixed airflow obstruction in children and adolescents with asthma: 4-Year follow-up.

    abstract:BACKGROUND:Asthma is a disease with reversible bronchoconstriction; however, some patients develop fixed airflow obstruction (FAO). Previous studies have reported the incidence and risk factors of FAO in adults; however, the corresponding factors in children remain poorly understood. AIM:To evaluate the incidence and ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24625

    authors: Sousa AW,Barros Cabral AL,Arruda Martins M,Carvalho CRF

    更新日期:2020-03-01 00:00:00

  • High-sensitivity C reactive protein as a biomarker for grading of childhood asthma in relation to clinical classification, induced sputum cellularity, and spirometry.

    abstract:BACKGROUND:Asthma is the most common chronic inflammatory disease in childhood and some reports have demonstrated systemic inflammation. The relevance of high-sensitivity assays for C-reactive protein (hs-CRP), which are known to be a sensitive marker of low-grade systemic inflammation, has not been fully studied in ch...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21539

    authors: Deraz TE,Kamel TB,El-Kerdany TA,El-Ghazoly HM

    更新日期:2012-03-01 00:00:00

  • Impulse oscillometry: a measure for airway obstruction.

    abstract::The impulse oscillometry system (IOS) was introduced as a new technique to assess airflow obstruction in patients who are not able to perform forced breathing maneuvers, e.g., subjects with cerebral palsy or severe mental retardation, and young children. This study evaluates the sensitivity and specificity of IOS para...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.10235

    authors: Vink GR,Arets HG,van der Laag J,van der Ent CK

    更新日期:2003-03-01 00:00:00

  • Psychosocial characteristics of inner-city children with asthma: a description of the NCICAS psychosocial protocol. National Cooperative Inner-City Asthma Study.

    abstract::Previous research has demonstrated a significant reciprocal relationship between psychosocial factors and asthma morbidity in children. The National Cooperative Inner-City Asthma Study investigated both asthma-specific and non-specific psychosocial variables, including asthma knowledge beliefs and management behavior,...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/(sici)1099-0496(199710)24:4<263::aid-ppul5

    authors: Wade S,Weil C,Holden G,Mitchell H,Evans R 3rd,Kruszon-Moran D,Bauman L,Crain E,Eggleston P,Kattan M,Kercsmar C,Leickly F,Malveaux F,Wedner HJ

    更新日期:1997-10-01 00:00:00

  • Trampoline use as physiotherapy for cystic fibrosis patients.

    abstract::Physicians and physiotherapists who care for CF patients have recommended the use of trampolines as a physiotherapeutic tool for enhancing cardiopulmonary performance, encouraging sputum production, and improving general well-being. Despite some therapeutic and recreational benefits associated with trampoline use, pap...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,评审

    doi:10.1002/ppul.20133

    authors: Barak A,Wexler ID,Efrati O,Bentur L,Augarten A,Mussaffi H,Avital A,Rivlin J,Aviram M,Yahav Y,Kerem E

    更新日期:2005-01-01 00:00:00

  • Fertility treatments and the risk of pediatric obstructive sleep apnea in the offspring-Results from a population-based cohort study.

    abstract:OBJECTIVE:While the impact of fertility treatments on the perinatal outcome is well established, the long-term effects on offspring are yet to be determined. The current study aimed to investigate the risk of long-term obstructive sleep apnea (OSA) among children born following in vitro fertilization (IVF) and ovulatio...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.24428

    authors: Imterat M,Wainstock T,Sheiner E,Landau D,Walfisch A,Harlev A

    更新日期:2019-10-01 00:00:00

  • A simple method of reducing complications of pediatric nonbronchoscopic bronchoalveolar lavage.

    abstract::Our objective was to determine whether a simple method of maintaining positive pressure ventilation during nonbronchoscopic bronchoalveolar lavage (NB-BAL) would successfully reduce the incidence and/or severity of desaturation events. Our design was a clinical trial with historical controls. Seventy ventilated pediat...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20082

    authors: Morrow B,Futter M,Argent A

    更新日期:2004-09-01 00:00:00

  • Tracking of lung function in healthy children and adolescents.

    abstract::Two hundred twenty-six healthy school children, with a mean age of 8.8 years; 62 girls mean age 8.8, 48 boys mean age 12.6 and 51 girls mean age 12.6 years at the start, were enrolled in a longitudinal study of lung function and tested annually for 5 years. All were free of respiratory symptoms, and none smoked more t...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950080308

    authors: Hibbert ME,Hudson IL,Lanigan A,Landau LI,Phelan PD

    更新日期:1990-01-01 00:00:00

  • Lung clearance index: normal values, repeatability, and reproducibility in healthy children and adolescents.

    abstract::There is increasing interest in using the Multiple Breath Washout technique and the lung clearance index (LCI) for detecting early pulmonary changes, for example, in cystic fibrosis lung disease. However, there are still limited data regarding equipment specific reference ranges, repeatability and reproducibility. The...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21093

    authors: Fuchs SI,Eder J,Ellemunter H,Gappa M

    更新日期:2009-12-01 00:00:00

  • Pulmonary function and structure following mild preterm birth in lambs.

    abstract::Our objective was to determine whether postnatal respiratory function, lung growth, and lung structure are affected by preterm birth which did not require neonatal respiratory support. Two groups of preterm (P) lambs were delivered 2 weeks before term, at 133 days of gestational age (GA). Tissue was collected at term ...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20274

    authors: Cock M,Hanna M,Sozo F,Wallace M,Yawno T,Suzuki K,Maritz G,Hooper S,Harding R

    更新日期:2005-10-01 00:00:00

  • Congenital lung abnormality quantification by computed tomography: The CLAQ method.

    abstract:INTRODUCTION:To date, no consensus has been reached on the optimal management of congenital lung abnormalities, and factors predicting postnatal outcome have not been identified. We developed an objective quantitative computed tomography (CT) scoring method, and assessed its value for clinical decision-making. METHODS...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.25032

    authors: Hermelijn SM,Dragt OV,Bosch JJ,Hijkoop A,Riera L,Ciet P,Wijnen RMH,Schnater JM,Tiddens HAWM

    更新日期:2020-11-01 00:00:00

  • Prophylaxis against respiratory syncytial virus in young children with cystic fibrosis.

    abstract:INTRODUCTION:In cystic fibrosis (CF) patients, respiratory syncytial virus (RSV) infection is associated with significant morbidity. Although passive prophylaxis with palivizumab lowers hospitalization rate for RSV infection in populations at risk of severe infection, its use is not recommended in infants with CF disea...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20751

    authors: Giebels K,Marcotte JE,Podoba J,Rousseau C,Denis MH,Fauvel V,Laberge S

    更新日期:2008-02-01 00:00:00

  • Pediatricians' attitudes and costs of bronchiolitis in the emergency department: a prospective multicentre study.

    abstract:BACKGROUND:How pediatricians manage bronchiolitis and the derived total costs (direct and indirect) in the emergency department (ED) have not been fully characterized. The aim of the present study is to calculate those costs in a European country. METHODS:A prospective and observational study, including 10 EDs of tert...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,多中心研究

    doi:10.1002/ppul.22906

    authors: Garcia-Marcos L,Valverde-Molina J,Pavlovic-Nesic S,Claret-Teruel G,Peñalba-Citores AC,Nehme-Álvarez D,Korta-Murua J,Sánchez-Etxaniz J,Alonso-Salas MT,Campos-Calleja C,Fernández-Villar A,Rodríguez-Suarez J,BCOST group.

    更新日期:2014-10-01 00:00:00

  • Primary small cell bronchogenic carcinoma in a 14-year-old boy.

    abstract::A 14-year-old Korean boy was admitted with cough, hemoptysis, and fever. A chest X-ray showed a solitary pulmonary mass and pneumonitis. Bronchial biopsy by fiberoptic bronchoscopy revealed a poorly differentiated small cell carcinoma. All of the staging information indicated that the patient had limited disease. Duri...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/(sici)1099-0496(200004)29:4<317::aid-ppul1

    authors: Kim CK,Chung CY,Koh YY

    更新日期:2000-04-01 00:00:00

  • Factors that influence adherence to exercise and their effectiveness: application to cystic fibrosis.

    abstract::Appropriate, regular exercise is of benefit to patients with cystic fibrosis (CF). As with other segments of the population, it has been difficult to devise exercise programs to which most patients will adhere for long periods of time. In healthy children, factors that are related to positive exercise compliance inclu...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章,评审

    doi:10.1002/ppul.10126

    authors: Prasad SA,Cerny FJ

    更新日期:2002-07-01 00:00:00

  • Wheezing at 8 and 13 years: changing importance of bronchiolitis and passive smoking.

    abstract::A group of 153 children (51 with a history of bronchiolitis and 102 matched controls) were evaluated in a historical cohort study at a mean age of 8 years and again at 13 years to test the primary hypothesis that mild bronchiolitis, far more common than severe (hospitalized) bronchiolitis, predicts wheezing. A seconda...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950060303

    authors: McConnochie KM,Roghmann KJ

    更新日期:1989-01-01 00:00:00

  • Advance care planning in adolescents with cystic fibrosis: A quality improvement project.

    abstract:INTRODUCTION:Advance care planning (ACP), though recommended, has not been studied in adolescents with cystic fibrosis (CF). This quality improvement project engaged adolescents with advanced CF disease in ACP and assessed patient and CF provider attitudes and preferences regarding ACP discussions and tools. MATERIALS...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23559

    authors: Kazmerski TM,Weiner DJ,Matisko J,Schachner D,Lerch W,May C,Maurer SH

    更新日期:2016-12-01 00:00:00

  • Severe systemic adverse reaction to proton pump inhibitors in an infant.

    abstract::Episodes of respiratory distress with chest retraction and wheezing, sometimes associated with facial edema, were noted after administering the proton pump inhibitors omeprazole and esomeprazole in an infant with gastroesophageal reflux. The disturbances relieved dramatically after withdrawing the proton pump inhibito...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20616

    authors: Baldassarre E,Sagaon MM,Ferrarini A,Bianchetti MG

    更新日期:2007-06-01 00:00:00

  • Familial neuroendocrine cell hyperplasia of infancy.

    abstract:BACKGROUND:Neuroendocrine cell hyperplasia of infancy (NEHI) is a recently described children's interstitial lung disease (chILD) disorder of unknown etiology. It manifests clinically with tachypnea, retractions, hypoxemia, and crackles. The characteristic radiographic appearance consists of pulmonary hyperexpansion an...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.21219

    authors: Popler J,Gower WA,Mogayzel PJ Jr,Nogee LM,Langston C,Wilson AC,Hay TC,Deterding RR

    更新日期:2010-08-01 00:00:00

  • Evaluation of the multiple linear regression method to monitor respiratory mechanics in ventilated neonates and young children.

    abstract::A potentially useful method to monitor respiratory mechanics in artificially ventilated patients consists of analyzing the relationship between tracheal pressure (P), lung volume (V), and gas flow (V) by multiple linear regression (MLR) using a suitable model. Contrary to other methods, it does not require any particu...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950130307

    authors: Rousselot JM,Peslin R,Duvivier C

    更新日期:1992-07-01 00:00:00

  • Intrinsic catch-up growth of hypoplastic fetal lungs is mediated by interleukin-6.

    abstract::Fetal lung hypoplasia is a common finding in several fetal conditions such as congenital diaphragmatic hernia (CDH). Interestingly, previous studies have demonstrated that hypoplastic lungs have the ability to recover to normal size, when relieved from mechanical factors. However, the underlying mechanisms remain larg...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20840

    authors: Nogueira-Silva C,Moura RS,Esteves N,Gonzaga S,Correia-Pinto J

    更新日期:2008-07-01 00:00:00

  • Effects of maternal retinoic acid administration in a congenital diaphragmatic hernia rabbit model.

    abstract::Maternal retinoid administration has beneficial effects on lung development in the nitrofen rodent toxic model of congenital diaphragmatic hernia (DH). We wanted to investigate the effects in a surgical model, where the retinoid signaling pathway is not primarily disrupted by the toxic agent. We created DH in fetal ra...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.20829

    authors: Gallot D,Coste K,Jani J,Roubliova X,Marceau G,Velemir L,Verheyen A,Lemery D,Sapin V,Deprest J

    更新日期:2008-06-01 00:00:00

  • Relative contribution of ribcage and abdomen during augmented breaths in infants.

    abstract::Changes in the relative contribution of ribcage and abdomen during augmented breaths were assessed in two groups of infants (less than 2 weeks and 4-12 weeks old). In both groups ribcage and abdominal movements increased during augmented breaths in quiet sleep. In the older infants the relative increase was greater fo...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950040303

    authors: Mathew OP,Pronske ML,Clark ML

    更新日期:1988-01-01 00:00:00

  • Performance of a tracheostomy removal protocol for pediatric patients in rehabilitation after acquired brain injury: Factors associated with timing and possibility of decannulation.

    abstract:OBJECTIVES:We assessed the performance of a tracheostomy decannulation protocol privileging safety over quickness, in pediatric patients undergoing rehabilitation from severe acquired brain injury. We analyzed factors associated with decannulation timing and possibility and examined cases of failure. HYPOTHESIS:A safe...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23832

    authors: Pozzi M,Galbiati S,Locatelli F,Clementi E,Strazzer S

    更新日期:2017-11-01 00:00:00

  • Assessing ventilatory control in infants at high risk of sleep disordered breathing: a study of infants with cleft lip and/or palate.

    abstract::Neonatal exposure to intermittent hypoxia results in altered ventilatory response to subsequent hypoxia in animal models. The effect of similar exposure in human infants is unknown. Our objective was to determine the impact of sleep disordered breathing (SDB) in early infancy on ventilatory response in infants. We rec...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.22568

    authors: MacLean JE,Tan S,Fitzgerald DA,Waters KA

    更新日期:2013-03-01 00:00:00

  • Airway hyperreactivity is frequent in non-asthmatic children with sickle cell disease.

    abstract:BACKGROUND:Asthma is associated with poorer outcomes in sickle cell disease (SCD). Whether AHR can exist in SCD as a distinct entity, separate and independent of asthma, is unknown. AIMS:Our goal was to elucidate the prevalence of AHR, as measured by a methacholine challenge test (MCT), in children with SCD who did no...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.23374

    authors: Shilo NR,Alawadi A,Allard-Coutu A,Robitaille N,Pastore Y,Bérubé D,Jacob SV,Abish S,Dauletbaev N,Lands LC

    更新日期:2016-09-01 00:00:00

  • The delivery of therapeutic aerosols through endotracheal tubes.

    abstract::We used an in vitro model system to examine the sites of deposition of aqueous therapeutic aerosols administered through 3-mm, 6-mm, and 9-mm endotracheal tubes (commonly used in infants, children, and adults) at clinically relevant inspiratory flow rates. Aerosol was delivered to the endotracheal tube via a "T" piece...

    journal_title:Pediatric pulmonology

    pub_type: 杂志文章

    doi:10.1002/ppul.1950020108

    authors: Ahrens RC,Ries RA,Popendorf W,Wiese JA

    更新日期:1986-01-01 00:00:00