Airway hyperreactivity is frequent in non-asthmatic children with sickle cell disease.

abstract：BACKGROUND:Treatment of bronchopulmonary dysplasia (BPD) remains as yet an unmet clinical need and recently stem cells have been proposed as a therapeutic tool in animal models. We investigated the role of amniotic fluid stem cells (AFS) in an adult rat model of hyperoxia lung injury. METHODS:Fifty Sprague-Dawley rats...

journal_title：Pediatric pulmonology

authors： Grisafi D,Pozzobon M,Dedja A,Vanzo V,Tomanin R,Porzionato A,Macchi V,Salmaso R,Scarpa M,Cozzi E,Fassina A,Navaglia F,Maran C,Onisto M,Caenazzo L,De Coppi P,De Caro R,Chiandetti L,Zaramella P

更新日期：2013-11-01 00:00:00

abstract：:Lane-Hamilton syndrome refers to the uncommon co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co-existing non-diarrheal CD. Institution of gluten-free diet in each of the three children resulted in amelioration of th...

journal_title：Pediatric pulmonology

authors： Sethi GR,Singhal KK,Puri AS,Mantan M

更新日期：2011-03-01 00:00:00

abstract：:Drug reaction with eosinophilia and systemic symptom (DRESS) syndrome is a rare and severe side-effect, mainly described after intake of anticonvulsants, allopurinol, or antibiotics. It usually begins within 2 months after drug introduction. Symptoms include cutaneous rash, hematologic abnormalities, and internal orga...

journal_title：Pediatric pulmonology

authors： Gohy S,Froidure A,Lebecque P

更新日期：2017-04-01 00:00:00

abstract：:In 1994-1995 a cross-sectional epidemiological study investigating the respiratory health of school children in two Taiwan areas was conducted; one area was located in a region with petrochemical manufacturing complexes (Linyuan), and the other was situated in a reference area with no local industrial emissions (Taihs...

journal_title：Pediatric pulmonology

authors： Yang CY,Wang JD,Chan CC,Hwang JS,Chen PC

更新日期：1998-05-01 00:00:00

abstract：OBJECTIVE:To assess whether children with sleep-disordered breathing (SDB) symptom severity above a certain level, measured by a validated questionnaire, improve after adenotonsillectomy (AT) compared to no intervention. METHODS:Children with snoring and tonsillar hypertrophy (4 to 10-years old), who were candidates f...

journal_title：Pediatric pulmonology

authors： Papadakis CE,Chaidas K,Chimona TS,Zisoglou M,Ladias A,Proimos EK,Miligkos M,Kaditis AG

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:Among older children, sleep-disordered breathing (SDB) is associated with measurable neurocognitive consequences. However, diagnostic SDB thresholds are lacking for infants < 12 months. We sought to evaluate the relationship between SDB indices, gestational age (GA), and postmenstrual age (PMA) for infants wh...

journal_title：Pediatric pulmonology

authors： Matlen LB,Hassan F,Shellhaas RA

更新日期：2019-08-01 00:00:00

abstract：:Asynchronous or paradoxic motion between the rib cage and abdomen may be seen in infants with lung disease. We have recently shown that after bronchodilator administration, the degree of asynchrony decreases proportionately to the improvement in lung mechanics. However, whether such thoraco-abdominal asynchrony (TAA) ...

journal_title：Pediatric pulmonology

authors： Allen JL,Greenspan JS,Deoras KS,Keklikian E,Wolfson MR,Shaffer TH

更新日期：1991-01-01 00:00:00

abstract：OBJECTIVE:To describe and analyze the characteristics and the early risk factors for mortality of noninvasive ventilation (NIV) in critically ill children. STUDY DESIGN:A multicenter, prospective, observational 2-year study carried out with critically ill patients (1 month - 18 years of age) who needed NIV. Clinical d...

journal_title：Pediatric pulmonology

authors： López J,Pons-Òdena M,Medina A,Molinos-Norniella C,Palanca-Arias D,Demirkol D,León-González JS,López-Fernández YM,Perez-Baena L,López-Herce J,NIV Research Group.

更新日期：2020-12-31 00:00:00

abstract：OBJECTIVE:To define the benefits of a flexible bronchoscopy (FB) service in a Paediatric Intensive Care Unit (PICU). DESIGN:Review of the first 200 FBs undertaken in a large PICU. SETTING:Large cardiac and medical PICU in the United Kingdom, also providing extra-corporeal life support. PATIENTS:129 patients (78 male...

journal_title：Pediatric pulmonology

authors： Davidson MG,Coutts J,Bell G

更新日期：2008-12-01 00:00:00

abstract：OBJECTIVE:To determine the effect of changing electrode positions on vital signs and respiratory effort parameters measured with transcutaneous electromyography of the diaphragm (dEMG) in preterm infants. METHODS:In this observational study, simultaneous dEMG measurements were performed at the standard position and at...

journal_title：Pediatric pulmonology

authors： van Leuteren RW,Bekhuis RE,de Waal CG,de Jongh FH,van Kaam AH,Hutten GJ

更新日期：2020-02-01 00:00:00

abstract：:A variety of postnatal therapies have been and will be evaluated for prevention or treatment of neonatal chronic lung disease (CLD). A simple method for early selection of the highest risk infants would optimize intervention trials. Our study compared a clinical scoring system for predicting neonatal CLD (defined at 3...

journal_title：Pediatric pulmonology

authors： Yoder BA,Anwar MU,Clark RH

更新日期：1999-06-01 00:00:00

abstract：:Recurrent respiratory symptoms are common in preterm infants in the first 2 years of life. The aim of this study was to determine the lung function abnormalities associated with such symptoms. Forty preterm infants, with a median gestational age of 29 weeks were studied at a median postnatal age of 12 months. Twenty-t...

journal_title：Pediatric pulmonology

authors： Yuksel B,Greenough A

更新日期：1991-01-01 00:00:00

abstract：UNLABELLED:Data on central sleep apnea (CSA) and its significance in children are limited. Our objectives were to describe the polysomnogram (PSG) characteristics and clinical features of children with significant CSA at a single pediatric sleep center. STUDY DESIGN AND METHODS:A retrospective chart review of children...

journal_title：Pediatric pulmonology

authors： Kritzinger FE,Al-Saleh S,Narang I

更新日期：2011-10-01 00:00:00

abstract：:SUMMARY. The detection of early airway disease in infants with cystic fibrosis (CF) may lead to earlier intervention and an improved prognosis. We hypothesized that the ratio of maximal expiratory flows while breathing a mixture of helium and oxygen (heliox) and air, referred to as density dependence (DD), would ident...

journal_title：Pediatric pulmonology

authors： Davis S,Jones M,Kisling J,Howard J,Tepper RS

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Gastro-esophageal reflux (GOR) may contribute to lung disease in children with cystic fibrosis (CF). There is conflicting evidence regarding the effect of chest physiotherapy (CPT) in the head-down position on GOR. Furthermore, there is currently no evidence on the impact of physiotherapy on GOR as assessed ...

journal_title：Pediatric pulmonology

authors： Doumit M,Krishnan U,Jaffé A,Belessis Y

更新日期：2012-02-01 00:00:00

abstract：:A microbe-specific diagnosis in community-acquired pneumonia (CAP) is difficult in children, and studies on nonspecific chest radiographic and host response markers have been inconsistent. Serum procalcitonin (PCT) is a newly recognized, promising marker for differentiating between bacterial and viral infections. Seru...

journal_title：Pediatric pulmonology

authors： Korppi M,Remes S,Heiskanen-Kosma T

更新日期：2003-01-01 00:00:00

abstract：OBJECTIVE:The prevalence of obstructive sleep apnea (OSA) is higher in children with poorly controlled asthma. We aimed to determine the validity of the Pediatric Sleep Questionnaire (PSQ) to screen for OSA in children with asthma. METHODS:This retrospective review encompassed sleep studies and medical records of asth...

journal_title：Pediatric pulmonology

authors： Ehsan Z,Kercsmar CM,Collins J,Simakajornboon N

更新日期：2017-03-01 00:00:00

abstract：:Pulmonary function and exercise tolerance were evaluated in late childhood in two groups of prematurely born children: one group with bronchopulmonary dysplasia (BPD) [n = 15; gestational age at birth (GA): 29.6 +/- 2.8 weeks; birth weight (BW): 1,367 +/- 548 g; age at test: 7.9 +/- 0.6 years], and a second group with...

journal_title：Pediatric pulmonology

authors： Parat S,Moriette G,Delaperche MF,Escourrou P,Denjean A,Gaultier C

更新日期：1995-11-01 00:00:00

abstract：:To determine whether doses of ipratropium bromide (IB) greater than those usually administered by aerosol (75-250 micrograms) give a greater degree of protection from exercise-induced asthma (EIA) in children, 12 patients with chronic asthma, ages 7-13 yr, were challenged with methacholine and exercise after inhalatio...

journal_title：Pediatric pulmonology

authors： Boner AL,Vallone G,De Stefano G

更新日期：1989-01-01 00:00:00

abstract：:A thorough understanding of the early natural history of cystic fibrosis (CF) lung disease is critical for the development of effective interventions in the youngest patients. We assessed the evolution of pulmonary infection, inflammation, and clinical course among 40 infants over a 2-year period through annual bronch...

journal_title：Pediatric pulmonology

authors： Rosenfeld M,Gibson RL,McNamara S,Emerson J,Burns JL,Castile R,Hiatt P,McCoy K,Wilson CB,Inglis A,Smith A,Martin TR,Ramsey BW

更新日期：2001-11-01 00:00:00

abstract：:Short-acting β2-adrenergic receptor agonists are commonly used bronchodilators for symptom relief in asthmatics. Recent evidence demonstrated that prolonged exposure of cultured airway smooth muscle cells to β2 agonists directly augments procontractile signaling pathways with the change in expression of regulator of G...

journal_title：Pediatric pulmonology

authors： Labuda M,Laberge S,Brière J,Bérubé D,Krajinovic M

更新日期：2013-10-01 00:00:00

abstract：:We have evaluated the role of eosinophil cationic protein (ECP) concentrations in serum in predicting wheezing after bronchiolitis, during infancy and early childhood. A prospective study at a university hospital serving all pediatric patients in a defined area was designed. Serum ECP concentrations were measured in 9...

journal_title：Pediatric pulmonology

authors： Reijonen TM,Korppi M,Kuikka L,Savolainen K,Kleemola M,Mononen I,Remes K

更新日期：1997-06-01 00:00:00

abstract：:Exercise challenge tests are helpful in the diagnosis and management of childhood asthma, but methodology is complex and time-consuming. The aim of this study was to investigate whether exercise-induced bronchoconstriction (EIB) can be predicted by the results of different surrogate tests in a pediatric population. Ei...

journal_title：Pediatric pulmonology

authors： Lex C,Dymek S,Heying R,Kovacevic A,Kramm CM,Schuster A

更新日期：2007-03-01 00:00:00

abstract：:Specific airway resistance (SRaw) is conventionally determined by multiplying the plethysmographically measured values of airway resistance and functional residual capacity (FRC). An alternative single-step method, which avoids the need for airway occlusion during determination of FRC, has been described by Dab and Al...

journal_title：Pediatric pulmonology

authors： Haluszka J,Willim G,Cutrera R,Ronchetti R,Filtcher S

更新日期：1989-01-01 00:00:00

abstract：:Pulmonary function testing and monitoring plays an important role in the respiratory management of neonates. A noninvasive and complete bedside evaluation of the respiratory status is especially useful in critically ill neonates to assess disease severity and resolution and the response to pharmacological intervention...

journal_title：Pediatric pulmonology

authors： Reiterer F,Sivieri E,Abbasi S

更新日期：2015-10-01 00:00:00

abstract：:Previous research has demonstrated a significant reciprocal relationship between psychosocial factors and asthma morbidity in children. The National Cooperative Inner-City Asthma Study investigated both asthma-specific and non-specific psychosocial variables, including asthma knowledge beliefs and management behavior,...

journal_title：Pediatric pulmonology

authors： Wade S,Weil C,Holden G,Mitchell H,Evans R 3rd,Kruszon-Moran D,Bauman L,Crain E,Eggleston P,Kattan M,Kercsmar C,Leickly F,Malveaux F,Wedner HJ

更新日期：1997-10-01 00:00:00

abstract：BACKGROUND:There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the ...

journal_title：Pediatric pulmonology

authors： Ortiz LE,McGrath-Morrow SA,Sterni LM,Collaco JM

更新日期：2017-12-01 00:00:00

abstract：:Our aim was to evaluate long-term effects of exogenous surfactant therapy on pulmonary functional outcome in children born very preterm. We examined 40 children aged 7-12 years who were born before 30 weeks of gestation with an immature surfactant system, and were randomized to one of three treatment groups: human sur...

journal_title：Pediatric pulmonology

authors： Pelkonen AS,Hakulinen AL,Turpeinen M,Hallman M

更新日期：1998-03-01 00:00:00

abstract：BACKGROUND:Interferon-gamma (IFN-γ) and interferon-inducible protein of 10 kDa (IP-10) are potent inflammatory mediators and contribute to acute lung injury in adults. Recently, a potential role for IFN-γ and IP-10 in the pathogenesis of bronchopulmonary dysplasia (BPD) has been reported in animal models. OBJECTIVE:To...

journal_title：Pediatric pulmonology

authors： Aghai ZH,Saslow JG,Mody K,Eydelman R,Bhat V,Stahl G,Pyon K,Bhandari V

更新日期：2013-01-01 00:00:00

abstract：:The jet nebulizer is a common device used for administering aerosol medication in young children. However, compared to a metered dose inhaler-spacer (MDI-spacer), it takes more time and personnel. This study aimed to compare the efficacy of salbutamol aerosol therapy given via these two devices in young wheezing child...

journal_title：Pediatric pulmonology

authors： Deerojanawong J,Manuyakorn W,Prapphal N,Harnruthakorn C,Sritippayawan S,Samransamruajkit R

更新日期：2005-05-01 00:00:00