Benefit of gluten-free diet in idiopathic pulmonary hemosiderosis in association with celiac disease.

Abstract:

:Lane-Hamilton syndrome refers to the uncommon co-occurrence of idiopathic pulmonary hemosiderosis and celiac disease (CD). Three children aged between 7 and 14 years with IPH were detected to have co-existing non-diarrheal CD. Institution of gluten-free diet in each of the three children resulted in amelioration of the pulmonary symptoms along with improvement of anthropometric parameters and hemoglobin over a short-term follow-up period of 8-17 months. Inhaled/oral steroids and immunosuppressants could be weaned off after dietary exclusion therapy in each of the three children. Gluten free diet should be instituted in all patients diagnosed with Lane-Hamilton syndrome. It ameliorates both the pulmonary as well as the intestinal symptoms although the precise mechanism of the pulmonary response is as yet unclear.

journal_name

Pediatr Pulmonol

journal_title

Pediatric pulmonology

authors

Sethi GR,Singhal KK,Puri AS,Mantan M

doi

10.1002/ppul.21357

subject

Has Abstract

pub_date

2011-03-01 00:00:00

pages

302-5

issue

3

eissn

8755-6863

issn

1099-0496

journal_volume

46

pub_type

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