Comparison of a new multidose powder inhaler with a pressurized aerosol in children with asthma.

abstract：BACKGROUND:Percutaneous lymphatic intervention (PCL) is a promising new therapy for plastic bronchitis (PB). We characterized bronchoalveolar lavage (BAL) and cast morphology in surgically repaired congenital heart disease (CHD) patients with PB during PCL. We quantified respiratory and bronchoscopic characteristics an...

journal_title：Pediatric pulmonology

authors： Geanacopoulos AT,Savla JJ,Pogoriler J,Piccione J,Phinizy P,DeWitt AG,Blinder JJ,Pinto E,Itkin M,Dori Y,Goldfarb SB

更新日期：2018-11-01 00:00:00

abstract：OBJECTIVES:Sildenafil, tezosentan, and prostacyclin reduce pulmonary vascular pressures in pulmonary hypertension, but have potential to vasodilate the systemic circulation. Nebulized vasodilators allow targeted drug delivery, high local drug concentrations, less systemic hypotension, and better matching of the lung's ...

journal_title：Pediatric pulmonology

authors： Katz SL,Adatia I,Louca E,Leung K,Humpl T,Reyes JT,Coates AL

更新日期：2006-07-01 00:00:00

abstract：:The purpose of this study was to compare the pathogens obtained by oropharyngeal suction (OPS) and bronchoalveolar lavage (BAL) in children with chronic pulmonary infections. Forty-four children (mean age of 6.1 years; range 4 months to 15 years) were included in the study (27 children with recurrent localized lung in...

journal_title：Pediatric pulmonology

authors： Avital A,Uwyyed K,Picard E,Godfrey S,Springer C

更新日期：1995-07-01 00:00:00

abstract：BACKGROUND:Although the benefits of recombinant human deoxyribonuclease (dornase alfa) in patients with cystic fibrosis (CF) are established, its optimal timing in relation to physiotherapy is unknown. As its enzymatic effect lasts for 6-11 hr, dornase alfa may be more efficacious if the time interval between inhalatio...

journal_title：Pediatric pulmonology

authors： Wilson CJ,Robbins LJ,Murphy JM,Chang AB

更新日期：2007-12-01 00:00:00

abstract：BACKGROUND:Multiple breath washout (MBW) in infants presents a number of technical challenges. Conventional MBW is based on simultaneous measurement of flow and gas concentrations. These two signals are aligned and combined to derive expired gas volumes from which lung volumes and measures of ventilation inhomogeneity ...

journal_title：Pediatric pulmonology

authors： Shawcross A,Murray CS,Goddard N,Gupta R,Watson S,Horsley A

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:There are limited data on the effect of bronchopulmonary dysplasia (BPD) on sleep disordered breathing (SDB). We hypothesized that both the severity of prematurity and BPD would increase the likelihood of SDB in early childhood. Our secondary aim was to evaluate the association of demographic factors on the ...

journal_title：Pediatric pulmonology

authors： Ortiz LE,McGrath-Morrow SA,Sterni LM,Collaco JM

更新日期：2017-12-01 00:00:00

abstract：:"Pulmonary Interstitial Glycogenosis: Diagnostic Evaluation and Clinical Course," written by Liptzin et al is a timely and insightful phenotypic summary of a rare pediatric interstitial lung disease. Twenty-four infants with biopsy-proven pulmonary interstitial glycogenosis (PIG) were reviewed at their center. Genetic...

journal_title：Pediatric pulmonology

authors： Yonker LM,Kinane TB

更新日期：2018-12-01 00:00:00

abstract：:Four patients with severe cystic fibrosis lung disease, anorexia and weight loss, received Megestrol Acetate (MA), as an appetite stimulant. The initial dose was 400-800 mg daily and was continued for 6-15 months. Appetite was improved, with significant weight gain in all patients and an increase in their weight for a...

journal_title：Pediatric pulmonology

authors： Nasr SZ,Hurwitz ME,Brown RW,Elghoroury M,Rosen D

更新日期：1999-11-01 00:00:00

abstract：:The incidence of empyema complicating community-acquired pneumonia is increasing and causes significant childhood morbidity. Pneumococcal infection remains the most common isolated cause in developed countries, with Staphylococcus aureus the predominant pathogen in the developing world. Newer molecular techniques util...

journal_title：Pediatric pulmonology

authors： Jaffé A,Balfour-Lynn IM

更新日期：2005-08-01 00:00:00

abstract：:Neurally adjusted ventilatory assistance (NAVA) can overcome technical difficulties with synchronizing noninvasive ventilation breaths with the patient, a modality often used in very low birthweight infants (VLBW) with apnea of prematurity (AOP). This study is a retrospective single-center investigation into whether N...

journal_title：Pediatric pulmonology

authors： Tabacaru CR,Moores RR Jr,Khoury J,Rozycki HJ

更新日期：2019-11-01 00:00:00

abstract：OBJECTIVE:To evaluate safety and efficacy of oral posaconazole and terbinafine for Lomentospora prolificans and Scedosporium apiospermum in children with cystic fibrosis. METHODS:Retrospective case review. RESULTS:There were five children (four girls), median age 15.0 years; three had S. apiospermum and two had L. pr...

journal_title：Pediatric pulmonology

authors： Bentley S,Davies JC,Carr SB,Balfour-Lynn IM

更新日期：2020-08-01 00:00:00

abstract：:The purpose of the present study was to identify prognostic factors related to death in patients with cystic fibrosis (CF). Records of 127 patients with CF submitted to a systematic protocol were retrospectively reviewed. Prognostic factors associated with demographic, nutritional, clinical, and laboratory findings on...

journal_title：Pediatric pulmonology

authors： Oliveira MC,Reis FJ,Oliveira EA,Colosimo EA,Monteiro AP,Penna FJ

更新日期：2002-07-01 00:00:00

abstract：:Exercise-induced asthma (EIA) is a possible cause of poor physical performance in children. No data are available on the value of respiratory symptoms to discriminate children with bad physical fitness from children with EIA. We evaluated respiratory symptoms in school-age children during and after exercise in relatio...

journal_title：Pediatric pulmonology

authors： De Baets F,Bodart E,Dramaix-Wilmet M,Van Daele S,de Bilderling G,Masset S,Vermeire P,Michel O

更新日期：2005-04-01 00:00:00

abstract：:A neonate with severe neonatal asphyxia was treated with therapeutic hypothermia. He developed hypothermia-induced respiratory deterioration, after which congenital tracheal stenosis and pulmonary artery sling were diagnosed. Even low-grade hypothermia is likely to induce bronchial narrowing in neonates, especially in...

journal_title：Pediatric pulmonology

authors： Nakajima J,Sunohara D,Kawashima H

更新日期：2017-03-01 00:00:00

abstract：:There is currently no validated scoring system for quantification of airway secretions in children. A user friendly, valid scoring system of airway secretions during flexible bronchoscopy (FB) would be useful for comparative purposes in clinical medicine and research. The objective of this study was to validate our br...

journal_title：Pediatric pulmonology

authors： Chang AB,Faoagali J,Cox NC,Marchant JM,Dean B,Petsky HL,Masters IB

更新日期：2006-09-01 00:00:00

abstract：:Central ventilation disorders(1) and airway obstruction(2) with chronic hypoxemia are causally related to cor pulmonale. Pulmonary vascular resistance is often reversible, and hypoxic pulmonary hypertension often responds to treatment with supplemental oxygen. Oxygen therapy during sleep may be useful as a temporary p...

journal_title：Pediatric pulmonology

authors： Hoch B,Barth H

更新日期：2001-03-01 00:00:00

abstract：OBJECTIVE:Telomere length is associated with poorer lung health in older adults, possibly from cumulative risk factor exposure, but data are lacking in pediatric and population-based cohorts. We examined associations of telomere length with lung function in children and mid-life adults. METHODS:Data were drawn from a ...

journal_title：Pediatric pulmonology

authors： Nguyen MT,Saffery R,Burgner D,Lycett K,Vryer R,Grobler A,Dwyer T,Ranganathan S,Wake M

更新日期：2019-12-01 00:00:00

abstract：:End-tidal PCO2 (PETCO2) measurements from two commercially available neonatal infrared capnometers with different sampling systems and a mass spectrometer were compared with arterial PCO2 (PaCO2) to determine whether the former could predict the latter in mechanically ventilated rabbits with and without lung injury. T...

journal_title：Pediatric pulmonology

authors： Hopper AO,Nystrom GA,Deming DD,Brown WR,Peabody JL

更新日期：1994-03-01 00:00:00

abstract：OBJECTIVES:We evaluated safety and efficacy of recombinant human growth hormone (rhGH) for improving growth, lean body mass (LBM), pulmonary function, and exercise tolerance in children with cystic fibrosis (CF) and growth restriction. STUDY DESIGN:Multicenter, open-label, controlled clinical trial comparing outcomes ...

journal_title：Pediatric pulmonology

authors： Stalvey MS,Anbar RD,Konstan MW,Jacobs JR,Bakker B,Lippe B,Geller DE

更新日期：2012-03-01 00:00:00

abstract：:Angiogenesis is an important mechanism of airway remodeling in lung disease. We previously demonstrated that serum vascular endothelial growth factor (VEGF) is elevated in cystic fibrosis (CF) patients and declines with therapy for pulmonary exacerbation. We hypothesized that VEGF is elevated early in the course of CF...

journal_title：Pediatric pulmonology

authors： Watts KD,McColley SA

更新日期：2011-07-01 00:00:00

abstract：:The autoimmune manifestations of primary immunodeficiencies, such as autoimmune lymphoproliferative syndrome (ALPS) and common variable immunodeficiency (CVID), often constitute a great therapeutic challenge and have a significant impact on patients' morbidity and mortality. The most common autoimmune presentations ar...

journal_title：Pediatric pulmonology

authors： Bucciol G,Petrone A,Putti MC

更新日期：2017-10-01 00:00:00

abstract：:Allergic bronchopulmonary aspergillosis (ABPA) is a complication commonly encountered in patients with CF that produces significant respiratory morbidity. Chronic airway colonization with Aspergillus induces strong inflammatory responses with high IgE levels. Current guidelines for therapy include prolonged courses of...

journal_title：Pediatric pulmonology

authors： Zirbes JM,Milla CE

更新日期：2008-06-01 00:00:00

abstract：:Few data are known about the effects of sleep-related breathing disorders (SRBD) on the cardiovascular system in adolescents. Forty healthy adolescents (mean age, 13.7 +/- 1.6 years) answered a questionnaire regarding symptoms of sleep-related breathing disorders (SRBD) and underwent a cardiorespiratory polygraphy and...

journal_title：Pediatric pulmonology

authors： Sánchez-Armengol A,Rodríguez-Puras MJ,Fuentes-Pradera MA,Quintana-Gallego E,Borja-Urbano G,Cayuela A,Capote F

更新日期：2003-07-01 00:00:00

abstract：:Respiratory symptoms, atopy, and bronchial reactivity were measured in primary school children living in Lake Munmorah (LM), a coastal town near two power stations, and in Nelson Bay (NB), a coastal town free from any possible major sources of outdoor air pollution. A prevalence survey and longitudinal follow-up study...

journal_title：Pediatric pulmonology

authors： Henry RL,Abramson R,Adler JA,Wlodarcyzk J,Hensley MJ

更新日期：1991-01-01 00:00:00

abstract：:Environmental tobacco smoke, also called passive smoking, was shown to have adverse effects on the health of children. Hydrogen peroxide (H2O2) is proposed as a sensitive marker of oxidative injury and inflammatory processes in the airways, being increased in adult active cigarette smokers. We tested whether passive s...

journal_title：Pediatric pulmonology

authors： Doniec Z,Nowak D,Tomalak W,Pisiewicz K,Kurzawa R

更新日期：2005-01-01 00:00:00

abstract：:Extralobar pulmonary sequestration is a congenital lung malformation characterized by a non-functional lung segment with systemic feeding vessel. Over 90% of sequestrations are found in the thorax with less than 10% located in the abdomen. We present an unusual case of intra abdominal pulmonary sequestration, located ...

journal_title：Pediatric pulmonology

authors： Chouikh T,Berteloot L,Revillon Y,Delacourt C,Khen-Dunlop N

更新日期：2014-05-01 00:00:00

abstract：:Recurrent respiratory symptoms are common in preterm infants in the first 2 years of life. The aim of this study was to determine the lung function abnormalities associated with such symptoms. Forty preterm infants, with a median gestational age of 29 weeks were studied at a median postnatal age of 12 months. Twenty-t...

journal_title：Pediatric pulmonology

authors： Yuksel B,Greenough A

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND:Neuroendocrine cell hyperplasia of infancy (NEHI) is a recently described children's interstitial lung disease (chILD) disorder of unknown etiology. It manifests clinically with tachypnea, retractions, hypoxemia, and crackles. The characteristic radiographic appearance consists of pulmonary hyperexpansion an...

journal_title：Pediatric pulmonology

authors： Popler J,Gower WA,Mogayzel PJ Jr,Nogee LM,Langston C,Wilson AC,Hay TC,Deterding RR

更新日期：2010-08-01 00:00:00

abstract：:Stachybotrys chartarum (atra) is a toxic mold that grows on water-damaged cellulose-based materials. Research has revealed also that inhalation of S. chartarum spores caused marked changes in respiratory epithelium, especially to developing lungs. We analyzed the epigenetic potential of S. chartarum spore toxins on de...

journal_title：Pediatric pulmonology

authors： McCrae KC,Rand TG,Shaw RA,Mantsch HH,Sowa MG,Thliveris JA,Scott JE

更新日期：2007-07-01 00:00:00

abstract：:While the use of the raised volume rapid thoraco-abdominal compression (RVRTC) technique has been shown to provide new insights into airway and pulmonary pathophysiology in infants, and appears to resemble the spirometric techniques used in older subjects, there is as yet no consensus regarding measurement procedures,...

journal_title：Pediatric pulmonology

authors： Lum S,Hoo AF,Stocks J

更新日期：2002-11-01 00:00:00