Aerosol treatment with MNEI suppresses bacterial proliferation in a model of chronic Pseudomonas aeruginosa lung infection.

abstract：:Pulmonary function testing and monitoring plays an important role in the respiratory management of neonates. A noninvasive and complete bedside evaluation of the respiratory status is especially useful in critically ill neonates to assess disease severity and resolution and the response to pharmacological intervention...

journal_title：Pediatric pulmonology

authors： Reiterer F,Sivieri E,Abbasi S

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:Decreased lung function is common in preterm-born survivors. Increased fractional exhaled nitric oxide (FeNO) appears to be a reliable test for eosinophillic airway inflammation especially in asthma. We, systematically, reviewed the literature to compare FeNO levels in preterm-born children and adults who di...

journal_title：Pediatric pulmonology

authors： Course CW,Kotecha S,Kotecha SJ

更新日期：2019-05-01 00:00:00

abstract：:Pulmonary hemorrhage (PH) is a serious complication causing acute respiratory distress in the premature infant, and it is associated with significant mortality and morbidity. The role of inflammatory mediators in this condition is largely undefined. Serial tracheal aspirates (TA) were obtained at intervals from 65 mec...

journal_title：Pediatric pulmonology

authors： Baier RJ,Loggins J,Kruger TE

更新日期：2002-08-01 00:00:00

abstract：:Campomelic dysplasia is a generalized disorder of cartilaginous growth and development, leading to early death from pulmonary insufficiency. We describe the airway dynamics as observed bronchoscopically in two affected infants. Both infants demonstrated anatomic compromise of the upper airway and diffuse laryngotrache...

journal_title：Pediatric pulmonology

authors： Grad R,Sammut PH,Britton JR,Goodrich P,Hoyme HE,Dambro NN

更新日期：1987-09-01 00:00:00

abstract：:Standard chemotherapy for tuberculosis (TB) in children uses hepatotoxic drugs. Published data and guidelines on monitoring of liver function during TB treatment are often contradictory and not directly relevant to the pediatric population. We carefully monitored 43 children (age 6.6 years, 0.7-15.1 [median, range]; 4...

journal_title：Pediatric pulmonology

authors： Corrigan D,Paton J

更新日期：1999-01-01 00:00:00

abstract：:Patients with cystic fibrosis (CF) often experience acute pulmonary exacerbations (APE) and may be treated with a wide variety of intravenous antibiotics. The aim of this review is to provide an evidence-based summary of pharmacokinetic/pharmacodynamic (PK/PD), tolerability, and efficacy studies utilizing the intraven...

journal_title：Pediatric pulmonology

authors： Young DC,Zobell JT,Waters CD,Ampofo K,Stockmann C,Sherwin CM,Spigarelli MG

更新日期：2013-01-01 00:00:00

abstract：:The value of exercise testing as an objective measure of disease severity in patients with chronic chest diseases (CCD) is becoming increasingly recognized. The aim of this study was to investigate changes in oxygen uptake (VO2) during early recovery following maximal cardiopulmonary exercise testing (CPXT) in relatio...

journal_title：Pediatric pulmonology

authors： Stevens D,Oades PJ,Armstrong N,Williams CA

更新日期：2009-05-01 00:00:00

abstract：:We report a case of fungal pleural effusion secondary to presumed valproate induced pancreatitis with pseudocyst and stricture formation. A child with dyskinetic cerebral palsy who had been on sodium valproate for several years was transferred for drainage of a left sided pleural effusion. Pleural fluid culture consis...

journal_title：Pediatric pulmonology

authors： Gupta A,Marrs T,Urquhart D,Clarke S,Rosenthal M,Bush A

更新日期：2009-06-01 00:00:00

abstract：:The term "atypical" pneumonia has been used to differentiate infections caused by Chlamydia pneumoniae, Mycoplasma pneumoniae, Legionella, and other related organisms from pneumonia caused by classic bacteria, the prototype being Streptococcus pneumoniae. However, recent studies demonstrated that the clinical presenta...

journal_title：Pediatric pulmonology

authors： Hammerschlag MR

更新日期：2003-11-01 00:00:00

abstract：RATIONALE AND OBJECTIVES:Little is known about molecular changes in lungs of fetal rabbits with surgically induced diaphragmatic hernia (DH). Therefore, we examined in this model gene expressions of pivotal molecules for the developing lung. METHODS:At day 23 of gestation, DH was created in 12 fetuses from 4 does. Bot...

journal_title：Pediatric pulmonology

authors： Vuckovic A,Roubliova XI,Votino C,Naeije R,Jani JC

更新日期：2012-11-01 00:00:00

abstract：OBJECTIVE:The prevalence of obstructive sleep apnea (OSA) is higher in children with poorly controlled asthma. We aimed to determine the validity of the Pediatric Sleep Questionnaire (PSQ) to screen for OSA in children with asthma. METHODS:This retrospective review encompassed sleep studies and medical records of asth...

journal_title：Pediatric pulmonology

authors： Ehsan Z,Kercsmar CM,Collins J,Simakajornboon N

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:Mesenchymal stromal cell (MSC)-mediated therapeutic effects have been observed in the treatment of lung diseases. For the first time, this treatment was used as rescue therapy in a pediatric patient with a life-threatening respiratory syndrome associated with the filamin A (FLNA) gene mutation. METHODS:A ch...

journal_title：Pediatric pulmonology

authors： Pelizzo G,Avanzini MA,Lenta E,Mantelli M,Croce S,Catenacci L,Acquafredda G,Ferraro AL,Giambanco C,D'Amelio L,Giordano S,Re G,Zennaro F,Calcaterra V

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Consolidation on chest radiography is widely used as the reference standard for defining pneumonia and variability in interpretation is well known but not well explored or explained. METHODS:Three pediatric sub-specialists (infectious diseases, radiology and respiratory medicine) viewed 3,033 chest radiogra...

journal_title：Pediatric pulmonology

authors： Williams GJ,Macaskill P,Kerr M,Fitzgerald DA,Isaacs D,Codarini M,McCaskill M,Prelog K,Craig JC

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVES:A pilot study to compare pulmonary mechanics in a neonatal intensive care unit (NICU) cohort, specifically, comparing lung elastance between male and female infants in the NICU. HYPOTHESIS:Anecdotally, male infants are harder to ventilate than females. We hypothesize that males have higher model-based elast...

journal_title：Pediatric pulmonology

authors： Kim KT,Knopp J,Dixon B,Chase JG

更新日期：2020-01-01 00:00:00

abstract：:The free running test is a useful method for evaluation of exercise-induced bronchospasm in children. In young children this test simulates real-life circumstances and can be done more easily than histamine or methacholine challenges. The interrupter technique is a noninvasive method for measuring airflow resistance d...

journal_title：Pediatric pulmonology

authors： Kannisto S,Vanninen E,Remes K,Korppi M

更新日期：1999-03-01 00:00:00

abstract：:Dedicator of cytokinesis 8 (DOCK8) deficiency is an autosomal recessive type of combined immunodeficiency with elevated IgE. In this report, we describe a Japanese girl of non-consanguineous family suffering from acute eosinophilic pneumonia (AEP) as a presenting feature of DOCK8 deficiency. Although AEP was self-limi...

journal_title：Pediatric pulmonology

authors： Tsuge I,Ito K,Ohye T,Kando N,Kondo Y,Nakajima Y,Inuo C,Kurahashi H,Urisu A

更新日期：2014-03-01 00:00:00

abstract：:To promote early screening of patients with suspected Primary Ciliary Dyskinesia (PCD), nasal nitric oxide (nNO) measurements during tidal breathing (TB) have been developed for children unable to ensure velum closure (VC) during breath hold or expiration against resistance. To investigate technical and practical issu...

journal_title：Pediatric pulmonology

authors： Beydon N,Chambellan A,Alberti C,de Blic J,Clément A,Escudier E,Le Bourgeois M

更新日期：2015-12-01 00:00:00

abstract：:The aim of the study was to evaluate the effects of inhaled steroids (IS) on the improvement of clinical asthma symptoms and on the decrease in bronchial hyperreactivity (BHR). Twenty-four children with severe asthma were given 1,000 micrograms beclomethasone dipropionate (BDP) daily and compared with ten asthmatic co...

journal_title：Pediatric pulmonology

authors： Benoist MR,Brouard JJ,Rufin P,Waernessyckle S,de Blic J,Paupe J,Scheinmann P

更新日期：1992-06-01 00:00:00

abstract：:Necrotizing sarcoid granulomatosis (NSG) is characterized by pulmonary nodular infiltrates, a typical histology, and a benign clinical course. The etiology and pathogenesis of the disease are still unknown. In childhood, it is extremely rare, with only three reported cases so far. Here we report on an 8-year-old girl,...

journal_title：Pediatric pulmonology

authors： Heinrich D,Gordjani N,Trusen A,Marx A,Hebestreit H

更新日期：2003-05-01 00:00:00

abstract：:Maternal retinoid administration has beneficial effects on lung development in the nitrofen rodent toxic model of congenital diaphragmatic hernia (DH). We wanted to investigate the effects in a surgical model, where the retinoid signaling pathway is not primarily disrupted by the toxic agent. We created DH in fetal ra...

journal_title：Pediatric pulmonology

authors： Gallot D,Coste K,Jani J,Roubliova X,Marceau G,Velemir L,Verheyen A,Lemery D,Sapin V,Deprest J

更新日期：2008-06-01 00:00:00

abstract：BACKGROUND:Variation of lung function is considered to be a hallmark of asthma. Although guidelines recommend measuring it as a diagnostic tool for asthma, the usefulness of this approach has not been studied in children. AIM:To assess the usefulness of home spirometry in children with nonspecific lower respiratory tr...

journal_title：Pediatric pulmonology

authors： Brouwer AF,Visser CA,Duiverman EJ,Roorda RJ,Brand PL

更新日期：2010-04-01 00:00:00

abstract：BACKGROUND:The purpose of this study was to evaluate the utility of the Cystic Fibrosis Questionnaire-Revised (CFQ-R) with toddlers and preschool-aged children. Clinically relevant relations between health-related quality of life (HRQOL), stress, and mealtime behaviors have not been examined. It was hypothesized that p...

journal_title：Pediatric pulmonology

authors： Driscoll KA,Modi AC,Filigno SS,Brannon EE,Chamberlin LA,Stark LJ,Powers SW

更新日期：2015-06-01 00:00:00

abstract：:We used an in vitro model system to examine the sites of deposition of aqueous therapeutic aerosols administered through 3-mm, 6-mm, and 9-mm endotracheal tubes (commonly used in infants, children, and adults) at clinically relevant inspiratory flow rates. Aerosol was delivered to the endotracheal tube via a "T" piece...

journal_title：Pediatric pulmonology

authors： Ahrens RC,Ries RA,Popendorf W,Wiese JA

更新日期：1986-01-01 00:00:00

abstract：:A neonate with severe neonatal asphyxia was treated with therapeutic hypothermia. He developed hypothermia-induced respiratory deterioration, after which congenital tracheal stenosis and pulmonary artery sling were diagnosed. Even low-grade hypothermia is likely to induce bronchial narrowing in neonates, especially in...

journal_title：Pediatric pulmonology

authors： Nakajima J,Sunohara D,Kawashima H

更新日期：2017-03-01 00:00:00

abstract：RATIONALE:Increasing evidence suggests the forced oscillation technique (FOT) has the capacity to provide non-invasive monitoring and diagnosis of respiratory disease in young children. However, which FOT outcomes provide the most pertinent clinical information is currently unknown. The aim of this study was to determi...

journal_title：Pediatric pulmonology

authors： Evans DJ,Schultz A,Verheggen M,Hall GL,Simpson SJ

更新日期：2019-06-01 00:00:00

abstract：SUMMARY:Ataxia-telangiectasia (A-T) is a rare autosomal recessive disorder caused by mutations in the ATM gene, resulting in faulty repair of breakages in double-stranded DNA. The clinical phenotype is complex and is characterized by neurologic abnormalities, immunodeficiencies, susceptibility to malignancies, recurren...

journal_title：Pediatric pulmonology

authors： McGrath-Morrow SA,Gower WA,Rothblum-Oviatt C,Brody AS,Langston C,Fan LL,Lefton-Greif MA,Crawford TO,Troche M,Sandlund JT,Auwaerter PG,Easley B,Loughlin GM,Carroll JL,Lederman HM

更新日期：2010-09-01 00:00:00

abstract：UNLABELLED:Data on central sleep apnea (CSA) and its significance in children are limited. Our objectives were to describe the polysomnogram (PSG) characteristics and clinical features of children with significant CSA at a single pediatric sleep center. STUDY DESIGN AND METHODS:A retrospective chart review of children...

journal_title：Pediatric pulmonology

authors： Kritzinger FE,Al-Saleh S,Narang I

更新日期：2011-10-01 00:00:00

abstract：INTRODUCTION:The prevalence of both childhood obesity and childhood asthma has increased dramatically over the past few decades. Little is known concerning the role of body composition and lifestyle influences on airway health in children. PURPOSE:To determine whether body composition, fruit and vegetable intake (FV) ...

journal_title：Pediatric pulmonology

authors： Rosenkranz SK,Swain KE,Rosenkranz RR,Beckman B,Harms CA

更新日期：2011-05-01 00:00:00

abstract：:Lung scintigraphy has been used to evaluate the degree of pulmonary hypoplasia in infants with congenital diaphragmatic hernia (CDH). However, the relationship between lung scintigraphy and long-term outcome of CDH remains unclear. The aim of this study is to determine whether lung scintigraphy correlates with long-te...

journal_title：Pediatric pulmonology

authors： Okuyama H,Kubota A,Kawahara H,Oue T,Kitayama Y,Yagi M

更新日期：2006-09-01 00:00:00

abstract：:We report the case of a 4-year-old child with an atypical presentation of an aspirated unwitnessed foreign body in the airway. During an attempt to obtain a biopsy of what appeared to be a mucosal growth, the foreign body was removed. This may be the first report of foreign body removal in a child this young, using a ...

journal_title：Pediatric pulmonology

authors： Akhter J,Gaspar M,Bassuk A,Roberts J

更新日期：1994-07-01 00:00:00