Adiposity and low-grade systemic inflammation modulate matrix metalloproteinase-9 levels in Greek children with sleep apnea.

abstract：BACKGROUND:Asthma is associated with poorer outcomes in sickle cell disease (SCD). Whether AHR can exist in SCD as a distinct entity, separate and independent of asthma, is unknown. AIMS:Our goal was to elucidate the prevalence of AHR, as measured by a methacholine challenge test (MCT), in children with SCD who did no...

journal_title：Pediatric pulmonology

authors： Shilo NR,Alawadi A,Allard-Coutu A,Robitaille N,Pastore Y,Bérubé D,Jacob SV,Abish S,Dauletbaev N,Lands LC

更新日期：2016-09-01 00:00:00

abstract：AIM:The aim of this study was to investigate the status and effects of vitamin D supplement as adjuvant therapy in the management of respiratory distress syndrome (RDS) in preterm infants. PATIENT AND METHODS:Vitamin D was prospectively studied in 196 preterm neonates, 96 of them developed RDS, which further subdivide...

journal_title：Pediatric pulmonology

authors： Al-Beltagi M,Rowiesha M,Elmashad A,Elrifaey SM,Elhorany H,Koura HG

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Simulated exhaled nitric oxide (eNO) depends on ventilatory settings used in different experimental conditions. OBJECTIVES:To normalize the simulated minute exhaled nitric oxide according to different ventilatory settings. WORKING HYPOTHESIS:Different ventilatory settings influence the concentrations of ex...

journal_title：Pediatric pulmonology

authors： Figueras-Aloy J,Berrueco R,Salvia-Roiges MD,Rodríguez-Miguélez JM,Miracle-Echegoyen X,Botet-Mussons F,Mur-Sierra A,Vall O,Carbonell-Estrany X

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Interferon-gamma (IFN-γ) and interferon-inducible protein of 10 kDa (IP-10) are potent inflammatory mediators and contribute to acute lung injury in adults. Recently, a potential role for IFN-γ and IP-10 in the pathogenesis of bronchopulmonary dysplasia (BPD) has been reported in animal models. OBJECTIVE:To...

journal_title：Pediatric pulmonology

authors： Aghai ZH,Saslow JG,Mody K,Eydelman R,Bhat V,Stahl G,Pyon K,Bhandari V

更新日期：2013-01-01 00:00:00

abstract：:The term "atypical" pneumonia has been used to differentiate infections caused by Chlamydia pneumoniae, Mycoplasma pneumoniae, Legionella, and other related organisms from pneumonia caused by classic bacteria, the prototype being Streptococcus pneumoniae. However, recent studies demonstrated that the clinical presenta...

journal_title：Pediatric pulmonology

authors： Hammerschlag MR

更新日期：2003-11-01 00:00:00

abstract：:Lung hypoplasia is the main cause of congenital diaphragmatic hernia (CDH)-associated death but pathogenesis remains unclear. MiR-455-5p is involved in lung hypoplasia. We hypothesized that nitrofen causes abnormal miR-455-5p expression during lung development and designed this study to determine the relationship betw...

journal_title：Pediatric pulmonology

authors： Zheng J,He Q,Tang H,Li J,Xu H,Mao X,Liu G

更新日期：2020-06-01 00:00:00

abstract：:We present a child with interstitial lung disease (ILD) who was diagnosed with desquamative interstitial pneumonitis following CT thorax and open lung biopsy aged 2 years. Subsequently, surfactant protein gene analysis revealed mutations in the ABCA3 gene. This case of ABCA3 deficient ILD describes a stable clinical c...

journal_title：Pediatric pulmonology

authors： Williamson M,Wallis C

更新日期：2014-03-01 00:00:00

abstract：:Our study was aimed at elucidating the effect of strenuous maternal exercise (running at a speed of 20 m/min) on fetal somatic growth and lung development. Dams were separated into three groups: (1) exercising during the entire course of pregnancy; (2) exercising from the 16th to the 20th gestational day; and (3) cont...

journal_title：Pediatric pulmonology

authors： Nagai A,Sakamoto K,Konno K

更新日期：1993-06-01 00:00:00

abstract：:During the final prenatal period of fetal lung development in humans, important maturational processes occur, including the production of surfactant necessary to decrease surface tension at the air-liquid interface of the alveoli. During early gestation, the glucocorticoid receptor is expressed in the fetal lung, and ...

journal_title：Pediatric pulmonology

authors： Bolt RJ,van Weissenbruch MM,Lafeber HN,Delemarre-van de Waal HA

更新日期：2001-07-01 00:00:00

abstract：:We examined the effects of within-breath changes in compliance (C) upon the accuracy of measurements of compliance and resistance (R) by linear regression analysis and by Mead and Wittenberger's method. These effects were illustrated by a computer model and by lung models with linear and nonlinear pressure/volume rela...

journal_title：Pediatric pulmonology

authors： Silva Neto G,Gerhardt T,Silberberg A,Gerhardt T,Claure N,Duara S,Bancalari E

更新日期：1992-03-01 00:00:00

abstract：OBJECTIVES:To report the respiratory function of school-aged children with infantile Pompe disease (IPD) who started enzyme replacement therapy (ERT) in infancy and early childhood. STUDY DESIGN:This is a retrospective chart review of pulmonary function tests of: (a) patients with IPD 5 to 18 years of age, (b) who wer...

journal_title：Pediatric pulmonology

authors： ElMallah MK,Desai AK,Nading EB,DeArmey S,Kravitz RM,Kishnani PS

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Asthma is a chronic lower airway inflammatory disease. Nitric oxide is an inflammatory mediator produced endogenously in the airway. Previous studies have demonstrated that the fractional concentration of exhaled nitric oxide (FeNO) is increased in asthma. OBJECTIVES:To investigate if FeNO concentrations we...

journal_title：Pediatric pulmonology

authors： Oh MA,Shim JY,Jung YH,Seo JH,Young Kim H,Kwon JW,Kim BJ,Kim HB,Kim WK,Lee SY,Jang GC,Song DJ,Kim HJ,Shin YJ,Park JW,Cho SH,Lee JS,Hong SJ

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Evidence from recent studies suggests that IRT/PAP protocols may be successfully used as a purely biochemical newborn screening (NBS) for cystic fibrosis (CF) that does not require genetic screening. However, the experience with the performance of different IRT/PAP protocols remains limited. In this study, w...

journal_title：Pediatric pulmonology

authors： Sommerburg O,Hammermann J,Lindner M,Stahl M,Muckenthaler M,Kohlmueller D,Happich M,Kulozik AE,Stopsack M,Gahr M,Hoffmann GF,Mall MA

更新日期：2015-07-01 00:00:00

abstract：:We determined lung function at age 10 years in very low birthweight (VLBW,

journal_title：Pediatric pulmonology

authors： Palta M,Sadek-Badawi M,Madden K,Green C

更新日期：2007-09-01 00:00:00

abstract：OBJECTIVES:In hospitalized and nonhospitalized children with asthma exacerbations, we evaluated the determinants of (a) prolonged cough on day-14 and (b) asthma quality of life (QoL) questionnaires for parents (PACQLQ) on day-21. We hypothesized that children with more severe acute asthma are more likely to have prolon...

journal_title：Pediatric pulmonology

authors： Teoh L,Chatfield MD,Acworth JP,McCallum GB,Chang AB

更新日期：2020-11-12 00:00:00

abstract：OBJECTIVES:Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infections worldwide, causing disproportionate morbidity and mortality in infants and children. Infants with stronger Th1 responses have less severe disease, yet little is known about the infant T-cell response within the air spa...

journal_title：Pediatric pulmonology

authors： Eichinger KM,Kosanovich JL,Empey KM

更新日期：2018-02-01 00:00:00

abstract：:To determine whether doses of ipratropium bromide (IB) greater than those usually administered by aerosol (75-250 micrograms) give a greater degree of protection from exercise-induced asthma (EIA) in children, 12 patients with chronic asthma, ages 7-13 yr, were challenged with methacholine and exercise after inhalatio...

journal_title：Pediatric pulmonology

authors： Boner AL,Vallone G,De Stefano G

更新日期：1989-01-01 00:00:00

abstract：OBJECTIVE:Extremely low gestational age neonates (ELGANs) are at risk for pulmonary hypertension (PH). We hypothesized that PH, defined by echocardiogram at 36 weeks gestational age (GA), would associate with respiratory morbidity, increased oxidant stress, and reduced nitric oxide production. STUDY DESIGN:ELGANs in t...

journal_title：Pediatric pulmonology

authors： O'Connor MG,Suthar D,Vera K,Slaughter JC,Maitre NL,Steele S,Beller A,Fike CD,Aschner JL,Moore PE,Austin ED

更新日期：2018-03-01 00:00:00

abstract：BACKGROUND:Social and family factors may influence the probability of achieving asthma control in children. Parents' quality of life has been insufficiently explored as a predictive factor linked to the probability of achieving disease control in asthmatic children. OBJECTIVE:Determine whether the parents' quality of ...

journal_title：Pediatric pulmonology

authors： Cano-Garcinuño A,Mora-Gandarillas I,Bercedo-Sanz A,Callén-Blecua MT,Castillo-Laita JA,Casares-Alonso I,Forns-Serrallonga D,Tauler-Toro E,Alonso-Bernardo LM,García-Merino Á,Moneo-Hernández I,Cortés-Rico O,Carvajal-Urueña I,Morel

更新日期：2016-07-01 00:00:00

abstract：UNLABELLED:Vascular rings (VR) may produce extrinsic compression of trachea and/or esophagus. Diagnosis relies on nonspecific clinical data from resulting compression and image studies, mainly angiography, computed tomography, and cardiovascular MRI. Because of their low incidence, diagnosis is often missed. The role o...

journal_title：Pediatric pulmonology

authors： Furuya ME,Vargas MH,Ramírez-Figueroa JL,Félix-Heredia JL,González-Ortíz B,Rodríguez-Hernández L,Vera-Canelo JM

更新日期：2010-06-01 00:00:00

abstract：:The autoimmune manifestations of primary immunodeficiencies, such as autoimmune lymphoproliferative syndrome (ALPS) and common variable immunodeficiency (CVID), often constitute a great therapeutic challenge and have a significant impact on patients' morbidity and mortality. The most common autoimmune presentations ar...

journal_title：Pediatric pulmonology

authors： Bucciol G,Petrone A,Putti MC

更新日期：2017-10-01 00:00:00

abstract：:IL-10 is an anti-inflammatory cytokine that may have a protective role in acute lung injury. IL-10 expression is affected by a single-nucleotide polymorphism (SNP) located at position -1082 (G to A). The A allele is associated with lower IL-10 production. Low IL-10 production has been linked to the development of BPD....

journal_title：Pediatric pulmonology

authors： Yanamandra K,Boggs P,Loggins J,Baier RJ

更新日期：2005-05-01 00:00:00

abstract：:Sleep disordered breathing (SDB) represents a spectrum of breathing disorders, ranging from snoring to obstructive sleep apnea syndrome (OSAS), that disrupt nocturnal respiration and sleep architecture. OSAS is a common disorder in children, with a prevalence of 2-3%. It is associated with neurobehavioral, cognitive, ...

journal_title：Pediatric pulmonology

authors： Goldbart AD,Tal A

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:Premature neonates frequently require oxygen supplementation as a therapeutic intervention that, while necessary, also exposes the lung to significant oxidant stress. We hypothesized that hyperoxia has a deleterious effect on alveolar epithelial barrier function rendering the neonatal lung susceptible to inj...

journal_title：Pediatric pulmonology

authors： Vyas-Read S,Vance RJ,Wang W,Colvocoresses-Dodds J,Brown LA,Koval M

更新日期：2018-01-01 00:00:00

abstract：AIM:Our aim was to evaluate the correlation of Adenosine monophosphate challenge test (AMP-PCW) results with the patients' subsequent clinical course. METHODS:We performed a 6-year retrospective cohort study of young children with suspected asthma who underwent AMP-PCW test. RESULTS:Fifty four children were included ...

journal_title：Pediatric pulmonology

authors： Levin G,Rottensctreich A,Picard E,Avital A,Springer C,Cohen S

更新日期：2019-07-01 00:00:00

abstract：:Five children with positive serology for human immunodeficiency virus (HIV) infection by enzyme-linked immunosorbent assay and Western blot were followed for chronic pulmonary disease. Lung biopsies were performed in all patients, and confirmed the diagnosis of pulmonary lymphoid hyperplasia. All children demonstrated...

journal_title：Pediatric pulmonology

authors： Rubinstein A,Bernstein LJ,Charytan M,Krieger BZ,Ziprkowski M

更新日期：1988-01-01 00:00:00

abstract：:We studied the effect of low-protein diet (8% casein) on lung growth in rats from 3 to 7 weeks of age. Their diet was isocaloric with that of control animals fed a diet of 20% casein. The calorie intake of experimental animals was increased during the first 3 weeks of the experiment, but they increased less (about 10%...

journal_title：Pediatric pulmonology

authors： Matsui R,Thurlbeck WM,Fujita Y,Yu SY,Kida K

更新日期：1989-01-01 00:00:00

abstract：:Our objective was to determine the repeatability of bronchial responsiveness to mannitol dry powder (MDP) as an objective marker of asthma in children. MDP challenge was performed in children with stable asthma at the same time of the day on two separate occasions within a week. The test was terminated after a 15% fal...

journal_title：Pediatric pulmonology

authors： Barben J,Roberts M,Chew N,Carlin JB,Robertson CF

更新日期：2003-12-01 00:00:00

abstract：:The fixed-combination metered aerosol lK6 (fenoterol 0.05 mg/puff, ipratropium bromide 0.02 mg/puff--Berodual, Boehringer-Ingelheim Ltd., Ridgefield, Conn.) was administered to 12 children (8 boys, 4 girls) aged 3 1/2 to 6 2/12 years who had extrinsic bronchial asthma. Three forms of administration, each with a differ...

journal_title：Pediatric pulmonology

authors： Berdel D,Kellersmann U

更新日期：1985-11-01 00:00:00

abstract：:One hundred fifty-four children with recurrent or chronic infections of the lower respiratory tract compatible with the diagnosis of primary ciliary dyskinesia (PCD) were evaluated for the presence of ultrastructural ciliary abnormalities. Studies were performed on multiple samples of respiratory mucosa obtained by na...

journal_title：Pediatric pulmonology

authors： Barlocco EG,Valletta EA,Canciani M,Lungarella G,Gardi C,De Santi MM,Mastella G

更新日期：1991-01-01 00:00:00