Abstract：
:A cohort study on platers in Tokyo was carried out using the records of the Tokyo Health Insurance Society of Plating Industry. The type of work and chromium-exposure history of each member of this society was investigated by a questionnaire sent to the manager of each factory. The recovery rate of the questionnaire was 70.5%. Survival information on retired subjects was obtained from the offices of Japanese family registration system ("koseki").As the result, among 889 male chromium platers who were followed up from April 1, 1970 to September 30, 1976, 19 deaths were observed, but there were no cases of lung cancer. The observed number of deaths was only 50% of the expected number, which had been calculated using the annual male mortality by age of Tokyo. In contrast, a slightly higher number of deaths than expected (107%) was observed in the control group consisting of workers selected from the same factories as the chromium platers. Two types of possible error were considered in this study: the first is that deaths from the chromium-exposed group had been incorrectly assigned to the control group, and the second is that the 30% of nonresponders included a significant number of factories where chromium-related deaths had occurred.However, the response for surviving cases on the history of chromium handling is considered to be reliable. Thus it was decided to conduct a further study focusing on those workers alive on October 1, 1976.
journal_name
Biol Trace Elem Resjournal_title
Biological trace element researchauthors
Okubo T,Tsuchiya Kdoi
10.1007/BF02783841subject
Has Abstractpub_date
1979-03-01 00:00:00pages
35-44issue
1eissn
0163-4984issn
1559-0720journal_volume
1pub_type
杂志文章abstract：:This study was aimed to assess the protective effect of sodium selenite on the ileum mucosal immunologic injury induced by AFB1. One hundred eighty-one-day-old healthy male Avian broilers were divided into four groups of three replicates and 15 birds per replicate and fed with basal diet (control group), 0.3 mg/kg AFB...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0035-3
更新日期：2014-07-01 00:00:00
abstract：:The origins of the usage of different substances in beauty, skin, body, hair, and nails care products can be found in ancient times. To achieve better quality and enhance their effects, some additives such as preservatives, stabilizers, mineral pigments, dye, and shine were added to these products. Some of these subst...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0477-2
更新日期：2016-04-01 00:00:00
abstract：:Synaptosomes are used as an ex vivo model in the investigation of neuronal transmission and neurodegenerative processes. In this study, we aimed to determine the protective effects of boric acid (BA) and curcumin, which have antioxidant and anti-inflammatory properties, on Aβ1-42 induced neurodegenerative damage. Syna...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02511-2
更新日期：2020-11-25 00:00:00
abstract：:Nutritional profile of minerals and antioxidants in Indian spice extracts was evaluated in order to examine their efficacy in treating various diseases, disorders, and allergies in human health. Extracts of four medicinal plants such as Curcuma longa, Zingiber officinale, Piper nigrum, and Piper longum, regularly cons...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02228-2
更新日期：2021-03-01 00:00:00
abstract：:The causes of night blindness in children are multifactorial, and particular consideration has been given to childhood nutritional deficiency, which is the most common problem found in underdeveloped countries. Such deficiency can result in physiological and pathological processes that in turn influence hair compositi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8789-8
更新日期：2011-09-01 00:00:00
abstract：:Lanthanum cations (La 3+) are well known for their inhibitory actions on calcium channels. Prenatal lanthanum exposure may affect the development of embryo and alter the capacity for learning and memory in adults, and the one-trial passive avoidance learning paradigm with day-old chicks is an excellent model to study ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-008-8225-5
更新日期：2009-01-01 00:00:00
abstract：:Nano-titanium dioxide is a kind of widely used nanomaterial that exhibits various adverse outcomes. However, the role of oxidative stress in this regard remains controversial. This study aimed to evaluate whether oxidative stress is one of the toxicity mechanisms induced by nano-titanium dioxide in rats and mice model...
journal_title：Biological trace element research
pub_type： 杂志文章,meta分析
doi：10.1007/s12011-019-01761-z
更新日期：2020-03-01 00:00:00
abstract：:Fluoride (F) concentration in blood serum of healthy dromedary camel population was measured, and its relationship with age and sex was determined. In male animals, the level varied from 0.017 to 0.296 ppm, with mean (± S.E.) value of 0.163 ± 0.013 ppm. In females, the level varied from 0.036 to 0.372 ppm with mean va...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02534-9
更新日期：2021-01-06 00:00:00
abstract：:Magnesium is the second most abundant intracellular cation and is a fundamental cofactor in a multitude of cellular enzymatic reactions. Magnesium deficiency causes diverse clinical features predominantly due to cardio- and neurotoxicity. We describe a case of severe hypomagnesaemia associated with intermittent downbe...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8757-3
更新日期：2011-08-01 00:00:00
abstract：:The key role of osteoblasts in skeletal fluorosis makes the exploration of the possible mechanisms of the fluoride-induced oxidative stress of osteoblasts of great importance. In this article, the in vitro effects of fluoride on the oxidative stress of osteoblasts are presented. To study the inhibitory effect of baica...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02685921
更新日期：2007-04-01 00:00:00
abstract：:Plasma zinc (Zn), copper (Cu), and magnesium (Mg) concentrations, copper/zinc ratio, and selenium (Se) status were studied in 44 vegetarians (22 males and 22 females) and their age- and sex-matched nonvegetarians in the Bratislava region (Slovakia). Vegetarians had statistically significant lower levels of plasma Zn a...
journal_title：Biological trace element research
pub_type： 临床试验,杂志文章
doi：10.1007/BF02789145
更新日期：1995-10-01 00:00:00
abstract：:Quercetin, a plant-derived flavonoid, is frequently used as an antioxidant for efficient anti-oxidative capacity. However, whether quercetin has protective effects on goat sperm and preimplantation embryos against Cd2+-induced oxidative injury is still unclear. So, we researched the influence of quercetin on goat sper...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1255-8
更新日期：2018-10-01 00:00:00
abstract：:Timed-mated Sprague-Dawley rats (60/group) were exposed to boric acid (BA) from gestational days (gd) 0 to 20. BA added to the diet (0, 0.025, 0.050, 0.075, 0.1, or 0.2%) yielded boron (B) intakes of <0.35 (control), 3, 6, 10, 13, or 25 mg B/kg body wt/d. Approximately one-half of the dams/group were terminated on gd ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783148
更新日期：1998-01-01 00:00:00
abstract：:Methylmercury (MeHg) is highly toxic, and its principal target tissue in human is the nervous system, which has made MeHg intoxication a public health concern for many decades. Portulaca oleraceae (purslane), a member of the Portulacaceae family, is widespread as a weed and has been ranked the eighth most common plant...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-015-0546-6
更新日期：2016-07-01 00:00:00
abstract：:An experiment was conducted in a 3 × 3 (Cu × Zn) factorial experiment based on a completely randomized design to evaluate the effects of dietary copper and zinc on apparent mineral retention and serum biochemical indicators in young male mink on a corn-fish meal based diet. Animals were fed basal diets supplemented wi...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-014-0220-4
更新日期：2015-05-01 00:00:00
abstract：:Chromium (Cr), manganese (Mn), copper (Cu), zinc (Zn), and iron (Fe) concentrations were quantified in serum (n = 112), milk (n = 112), liver (n = 70), and kidney samples (n = 67) of dairy cows from an iron-steel processing region (Payas-Iskenderun) and from an area free of industrial pollution (Antakya) in Hatay, loc...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1385/BTER:98:1:51
更新日期：2004-04-01 00:00:00
abstract：:Tibetan sheep have been observed with mineral deficiencies and marginal deficiencies in Qinghai-Tibetan Plateau. Adequate amounts of essential minerals are critical to maximize the productivity and health of livestock. The objectives of this study were to evaluate the effects of 6 months of mineral block supplementati...
journal_title：Biological trace element research
pub_type： 杂志文章,随机对照试验
doi：10.1007/s12011-015-0593-z
更新日期：2016-08-01 00:00:00
abstract：:Because nickel may have a biological function in a pathway in which vitamin B12 is important, an experiment was performed to determine the effects of nitrous oxide exposure in rats deprived of nickel. Exposure to nitrous oxide (N2O) causes inactivation of cobalamin and a subsequent decrease in the vitamin B12-dependen...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783980
更新日期：1993-07-01 00:00:00
abstract：:This study investigated the effects of ethanol (EtOH) on manganese (Mn)-induced striatal toxicity in rat by evaluating the neurobehavioral changes, biochemical and molecular events in rats exposed to Mn alone at 30 mg/kg, or their combination with EtOH at 1.25- and 5-g/kg body weight for 35 consecutive days. Locomotiv...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1587-4
更新日期：2019-09-01 00:00:00
abstract：:The phosphorus NMR profile of normal and vanadium-treated chick muscle was obtained in vivo. The data show that the differentiation of breast and thigh muscles in terms of pH, lipid related metabolites, and bioenergetic parameters can be readily followed. Although the vanadium-treated chicks showed substantial retarda...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02990427
更新日期：1991-11-01 00:00:00
abstract：:This study was focused on the analysis of arsenic (As) levels in scalp hair of children (age, <10 years) collected from two towns of Khairpur, Pakistan, to evaluate the effects of As-contaminated groundwater. For comparative purposes, scalp hair samples of children were also collected from that area having low levels ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8866-z
更新日期：2011-10-01 00:00:00
abstract：:The aim of this study was to evaluate and compare the oxidative profiles of three thyroid disorders: Graves' disease (GD), Hashimoto thyroiditis (HT), and papillary thyroid cancer (PTC). Malondialdehyde levels (MDA), glutathione peroxidase (GPx), superoxide dismutase (SOD), and catalase (CAT) activities were examined ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8625-1
更新日期：2010-12-01 00:00:00
abstract：:Injectable trace minerals (ITMs) could provide a potential alternative way of trace mineral delivery for sick animals. Therefore, evaluation of ameliorative potentials of ITMs (copper, manganese, selenium, and zinc) on the circulating Th1/Th2 cytokine misbalance in Theileria annulata-infected calves was aimed. Forty-t...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02263-z
更新日期：2020-06-22 00:00:00
abstract：:The objective was to determine if a mammary cell line shows glucocorticoid stimulation of Zn uptake, and to determine whether polyamines mediate this stimulation. 65Zn uptake by COMMA-1D mouse mammary epithelial cells over a 24-h period increased significantly in cells administered 10(-7) or 10(-6) M hydrocortisone. I...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02783193
更新日期：1993-11-01 00:00:00
abstract：:Wild barley (Hordeum spontaneum), the progenitor of cultivated barley, is an important genetic resource for cereal improvement. Selenium (Se) is an essential trace mineral for humans and animals with antioxidant, anticancer, antiarthropathy, and antiviral effects. In the current study, the grain Se concentration (GSeC...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8770-6
更新日期：2011-09-01 00:00:00
abstract：:The seeds of Nelumbo nucifera (Lotus) have been used in the traditional system of medicine for various ailments including diabetes. The present study was aimed at analyzing the levels of biologically important trace elements in the lotus seeds by atomic absorption spectroscopy and evaluating the hypoglycemic propertie...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-010-8614-4
更新日期：2010-12-01 00:00:00
abstract：:Overall nutritional status has been proved associated with people's health. The overall nutritional status of children in Kashin-Beck disease (KBD) areas has been overlooked for decades. Therefore, it is worth investigating in the current generation to gather evidence and make suggestions for improvement. A cross-sect...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-017-1154-4
更新日期：2018-06-01 00:00:00
abstract：:An experimental study was conducted in Wistar rats to characterize the arsenic ("As")-induced alterations in neurobiochemistry in brain and its impact on neuropharmacological activities with or without the melatonin (MLT) as an antioxidant given exogenously. Male Wistar rats were randomly divided in to four groups of ...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-018-1537-1
更新日期：2019-07-01 00:00:00
abstract：:Hexavalent chromium, a well-known environmental toxicant, adversely affects female reproduction and results in abnormal implantation, fetal resorption, and reduction in litter size. Uterine myogenic activity is under control of number of receptors and ion channels, and it regulates fetal-implantation and feto-maternal...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/s12011-020-02041-x
更新日期：2020-11-01 00:00:00
abstract：:In a controlled animal experiment the effects of dietary subacute Zn deficiency on growth, Zn concentration, and tissue 42-K distribution were studied. Growth retardation caused lower body weight because both skeletal and heart muscle showed a reduction in cell mass. Zn concentrations were reduced in most tissues, how...
journal_title：Biological trace element research
pub_type： 杂志文章
doi：10.1007/BF02789301
更新日期：1994-12-01 00:00:00
