Nucleotide sequence and variability of the inverted terminal repetitions of African swine fever virus DNA.

abstract：:A new strain of wound tumor virus (WTV) has been isolated from a periwinkle plant (Catharanthus roseus) that was among several used as bait plants in a blueberry field. The 12 segments of double-stranded RNA of the viral genome were isolated directly from infected tissue and found to have mobilities through agarose ge...

journal_title：Virology

authors： Hillman BI,Anzola JV,Halpern BT,Cavileer TD,Nuss DL

更新日期：1991-12-01 00:00:00

abstract：:Six mutants of lambda having reduced dependence on the htpR function of Escherichia coli were isolated from lambda cIts857. Burst sizes in htpRts cells at 40.5 degrees were in the range of 10 to 20 particles per cell. Mapping and complementation analysis of one of the mutants suggested that the mutation in this isolat...

journal_title：Virology

authors： Fuerst CR

更新日期：1986-02-01 00:00:00

abstract：:Neutralizing antibodies (Nabs) are thought to play an important role in prevention and control of HIV-1 infection and should be targeted by an AIDS vaccine. It is critical to understand how HIV-1 induces Nabs by analyzing viral sequences in both tested viruses and sera. Neutralization susceptibility to antibodies in a...

journal_title：Virology

authors： Kirchherr JL,Hamilton J,Lu X,Gnanakaran S,Muldoon M,Daniels M,Kasongo W,Chalwe V,Mulenga C,Mwananyanda L,Musonda RM,Yuan X,Montefiori DC,Korber BT,Haynes BF,Gao F

更新日期：2011-01-20 00:00:00

abstract：:The terminal sequences of both genomic dsRNA segments of different strains of infectious bursal disease virus were determined. Analysis of the linear sequences revealed in the 5'-noncoding region of both segments the presence of a 32-nucleotide sequence with motifs conserved between segments and serotypes. The 3'-nonc...

journal_title：Virology

authors： Mundt E,Müller H

更新日期：1995-05-10 00:00:00

abstract：:The alphaherpesviruses establish latent infections in sensory neuronal cells, during which a number of latency-associated RNA transcripts (LATs) are produced. The reasons for the production of the LATs, however, and the mechanism by which the LAT region of the genome remains active during latency are unknown. Here we ...

journal_title：Virology

authors： Coffin RS,Howard MK,Latchman DS

更新日期：1995-06-01 00:00:00

abstract：:The measles virus RNA-dependent RNA polymerase consists of two virus-encoded subunits, the phosphoprotein (P) and the large (L) protein. The P mRNA also codes for a C protein in the +1 reading frame relative to P. The activities of the measles P and C proteins from the vaccine strain, EdB, a wild-type CM strain, and a...

journal_title：Virology

authors： Reutter GL,Cortese-Grogan C,Wilson J,Moyer SA

更新日期：2001-06-20 00:00:00

abstract：:In addition to the major ectodomain, the gp41 transmembrane glycoprotein of HIV-1 is now known to have a minor ectodomain that is part of the long C-terminal tail. Both ectodomains are highly antigenic, carry neutralizing and non-neutralizing epitopes, and are involved in virus-mediated fusion activity. However, data ...

journal_title：Virology

authors： Hollier MJ,Dimmock NJ

更新日期：2005-07-05 00:00:00

abstract：:A series of BglII- and Sau3A-derived fragments of phage T1 DNA were cloned into the plasmid vector pLV59 and the clones were tested for their ability to complement and recombine with infecting genomes of am mutants representing all known T1 essential genes. The resulting data were used to correlate the T1 genetic and ...

journal_title：Virology

authors： Liebeschuetz J,Ritchie DA

更新日期：1985-05-01 00:00:00

abstract：:In March 2017, a novel highly pathogenic avian influenza A(H7N9) virus was detected at two commercial broiler breeder facilities in Tennessee, United States. In this study, a wild bird low pathogenic avian influenza A virus, A/blue-winged teal/Wyoming/AH0099021/2016(H7N9), was shown to be the probable precursor of the...

journal_title：Virology

authors： Li L,DeLiberto TJ,Killian ML,Torchetti MK,Wan XF

更新日期：2018-12-01 00:00:00

abstract：:Varicella zoster virus (VZV) is a neurotropic alphaherpesvirus that, following primary infection (varicella), establishes latency in sensory, autonomic, sympathetic and parasympathetic neurons, where it remains until reactivation (zoster). VZV-specific cell-mediated immune responses maintain VZV latency; thus, immunos...

journal_title：Virology

authors： Como CN,Pearce CM,Cohrs RJ,Baird NL

更新日期：2018-09-01 00:00:00

abstract：:Hepatitis C virus (HCV) was shown to activate protein kinase R (PKR), which inhibits expression of interferon (IFN) and IFN-stimulated genes by controlling the translation of newly transcribed mRNAs. However, it is unknown exactly how HCV activates PKR. To address the molecular mechanism(s) of PKR activation mediated ...

journal_title：Virology

authors： Suzuki R,Matsuda M,Shimoike T,Watashi K,Aizaki H,Kato T,Suzuki T,Muramatsu M,Wakita T

更新日期：2019-03-01 00:00:00

abstract：:Mapping of the 5' ends of virion-derived hepatitis B virus DNA molecules was carried out after cloning and sequencing linearized genomes made fully double stranded. Of five clones obtained, three of four minus strand termini mapped to the G in position 1826 and one to the T in position 1827. Plus strand 5' ends were m...

journal_title：Virology

authors： Saldanha JA,Qiu H,Thomas HC,Monjardino J

更新日期：1992-05-01 00:00:00

abstract：:Norwalk virus (NV) is the prototype strain of a group of noncultivatable caliciviruses that infect humans and cause outbreaks of epidemic acute nonbacterial gastroenteritis. The NV virion is composed of 180 copies of a single structural protein that, when expressed in insect cells infected with a recombinant baculovir...

journal_title：Virology

authors： Hardy ME,Tanaka TN,Kitamoto N,White LJ,Ball JM,Jiang X,Estes MK

更新日期：1996-03-01 00:00:00

abstract：:We have used a microinjection approach to identify a domain of the simian virus 40 (SV40) structural proteins Vp2 and Vp3(Vp2/3) responsible for their nuclear transport. By using both synthetic peptides, containing small regions of Vp2/3 conjugated to bovine serum albumin (BSA), and beta-galactosidase-Vp3 fusion prote...

journal_title：Virology

authors： Clever J,Kasamatsu H

更新日期：1991-03-01 00:00:00

abstract：:Bovine immunodeficiency-like virus (BIV) is a recently identified lentivirus that infects cattle. The virus has structural and genetic similarities to human HIV. The present study demonstrates that BIV can be activated by bovine herpesvirus type 1 (BHV-1), a pathogen frequently associated with cattle diseases. Activat...

journal_title：Virology

authors： Geng Y,Kashanchi F,Wood C

更新日期：1992-04-01 00:00:00

abstract：:Tomato strain L of tobacco mosaic virus (TMV-L) induces a hypersensitive response (necrotic local lesions) on tobacco plants with the N' gene. A factor responsible for induction of the hypersensitive response has been mapped to the coat protein gene. We have constructed several mutants which have insertions or deletio...

journal_title：Virology

authors： Saito T,Yamanaka K,Watanabe Y,Takamatsu N,Meshi T,Okada Y

更新日期：1989-11-01 00:00:00

abstract：:Herpes simplex virus mutant KG111 contains a nonsense mutation at codon 44 of the viral thymidine kinase (tk) gene and produces low amounts of a truncated tk polypeptide. We tested mutant KG111 and related viruses that specify varying amounts of similar truncated tk polypeptides for their sensitivities to antiviral nu...

journal_title：Virology

authors： Coen DM,Irmiere AF,Jacobson JG,Kerns KM

更新日期：1989-02-01 00:00:00

abstract：:Crystals of Cowpea mosaic virus displaying a high degree of order have been grown in two different forms. Hexagonal crystals, space group P6(1)22 or P6(5)22 with a = 450 A and c = 1038 A containing six virus particles per cell, have been grown in sodium citrate buffer at pH 4.9. Each particle has four nearest neighbor...

journal_title：Virology

authors： White JM,Johnson JE

更新日期：1980-02-01 00:00:00

abstract：:We developed a positive selection method for recovering Marek's disease virus (MDV) recombinants. The Escherichia coli xanthine-guanine phosphoribosyltransferase gene (gpt), under the control of the major immediate-early promoter from cytomegalovirus, was inserted into the inverted repeats flanking the unique long (UL...

journal_title：Virology

authors： Marshall DR,Reilly JD,Liu X,Silva RF

更新日期：1993-08-01 00:00:00

abstract：:Infections of amphibians by Frog Virus 3 (FV3) and other ranavirus genus members are significantly contributing to the amphibian declines, yet much remains unknown regarding amphibian antiviral immunity. Notably, amphibians represent an important step in the evolution of antiviral interferon (IFN) cytokines as they ar...

journal_title：Virology

authors： Wendel ES,Yaparla A,Koubourli DV,Grayfer L

更新日期：2017-03-01 00:00:00

abstract：:In 2014-2015, the U.S. experienced an unprecedented outbreak of Eurasian clade 2.3.4.4 H5 highly pathogenic avian influenza (HPAI) virus, initially affecting mainly wild birds and few backyard and commercial poultry premises. To better model the outbreak, the pathogenesis and transmission dynamics of representative Eu...

journal_title：Virology

authors： Bertran K,Swayne DE,Pantin-Jackwood MJ,Kapczynski DR,Spackman E,Suarez DL

更新日期：2016-07-01 00:00:00

abstract：:Human papillomavirus type 16 (HPV 16) is often found in cervical carcinomas, while HPV 6 is frequently associated with benign genital lesions. We have compared the abilities of the E7 transforming proteins of HPV 6 and 16 to transform various established and primary rodent cells by using the same heterologous promoter...

journal_title：Virology

authors： Takami Y,Sasagawa T,Sudiro TM,Yutsudo M,Hakura A

更新日期：1992-02-01 00:00:00

abstract：:The role of the matrix (MA) domain of simian immunodeficiency virus (SIV) and bovine leukaemia virus (BLV) Gag in the assembly of virus-like particles (VLP) in insect cells has been investigated. Wild-type SIV and BLV Gag assembled to form discrete VLP structures typical of many retroviruses analysed by similar system...

journal_title：Virology

authors： Kakker NK,Mikhailov MV,Jones IM,Roy P

更新日期：2002-07-20 00:00:00

abstract：:Many antiviral drugs must be metabolized to their active form by cellular enzymes. Their antiviral activity may therefore be limited by an inefficient metabolism, leading to low intracellular concentration of the active form or to the accumulation of toxic intermediate metabolites. Gene transfer might be used to overc...

journal_title：Virology

authors： Guettari N,Loubière L,Brisson E,Klatzmann D

更新日期：1997-09-01 00:00:00

abstract：:Three SV40 escape mutants were identified by selection in the presence of monoclonal antibodies with neutralizing activity. The VP1 amino acid alterations in these mutants were: (1) K73-->E (in loop BC); (2) D77-->E (in loop BC); (3) K171-->R (in loop EF); and (4) Q175-->H (in loop EF). These residues are clustered in...

journal_title：Virology

authors： Murata H,Teferedegne B,Sheng L,Lewis AM Jr,Peden K

更新日期：2008-11-10 00:00:00

abstract：:We report here the nonenzymatic self-ligation of transcripts corresponding to the peach latent mosaic viroid (PLMVd). This is the first description of this process with viroid sequences, although it has been reported to occur with human hepatitis delta virus RNA. Self-ligation occurs when the 5'-hydroxyl and the 2',3'...

journal_title：Virology

authors： Lafontaine D,Beaudry D,Marquis P,Perreault JP

更新日期：1995-10-01 00:00:00

abstract：:Cucumber seedlings infected with cucumber mosaic virus (CMV) contain a virus-induced RNA-dependent RNA polymerase (RNA replicase) in both soluble and particulate fractions of plant extracts; no such activity is found in uninfected plants. The extensive purification and characterization of the soluble RNA replicase has...

journal_title：Virology

authors： Gill DS,Kumarasamy R,Symons RH

更新日期：1981-08-01 00:00:00

abstract：:The Autographa californica nuclear polyhedrosis virus da26 gene codes for an envelope protein of both budded virus (BV) and occlusion derived virus (ODV). Western blot and temporal analysis of infected cell extracts detected a protein of 26 kDa by 4 h postinfection (p.i.). The amount of protein increased by 16 h p.i. ...

journal_title：Virology

authors： Beniya H,Braunagel SC,Summers MD

更新日期：1998-01-05 00:00:00

abstract：:The synthesis and processing of the nucleocapsid protein (pp60) of the JHM strain of murine coronaviruses were examined. Pulse-chase experiments showed that pp60 was synthesized initially as a protein of approximately 57,000 in molecular weight (p57). Immunoprecipitation using mouse anti-JHMV antiserum indicated that ...

journal_title：Virology

authors： Stohlman SA,Fleming JO,Patton CD,Lai MM

更新日期：1983-10-30 00:00:00

abstract：:Each copy of the inverted terminal repeat of vaccinia virus consists of 8 kb of DNA containing 9 ORFS flanked near the terminus of the genome by 4 kb of repetitive DNA which in turn contains blocks of tandem repeats. Using plasmids containing repetitive DNA as the external arm, we have generated deletions at both the ...

journal_title：Virology

authors： Perkus ME,Goebel SJ,Davis SW,Johnson GP,Norton EK,Paoletti E

更新日期：1991-01-01 00:00:00