Efficacy of EMLA cream phonophoresis comparison with ultrasound therapy on myofascial pain syndrome of the trapezius: a single-blind, randomized clinical study.

Abstract:

:The aim of this study is to investigate whether eutectic mixture of local anesthetics (EMLA) cream phonophoresis superior to conventional US over the trigger points (TPs) in terms of improvements of pain, range of motion and disability in myofascial pain syndrome (MPS). Fifty patients (42 female, 8 male) diagnosed with MPS were included in the study. Patients were randomly assigned into two treatment groups including phonophoresis (PH) group (n = 25) and ultrasound (US) group (n = 25). PH group received EMLA cream phonophoresis (2.5 % lidocaine, 2.5 % prilocaine); US group received conventional ultrasound therapy over the all active TPs on trapezius muscle for 10 min a day for 15 sessions. Outcome measures were performed before the treatment course and at the end of a 15-session course of treatment. Student T, Mann-Whitney U, chi-square and Wilcoxon tests were used for statistical analysis. At the end of the therapy, there was statistically significant decrease in both PH group and US group in terms of number of trigger point (NTP) (p = 0.001, p = 0.029), pain intensity on movement (p = 0.001 vs. 0.002) and right/left cervical lateral ROMs (p = 0.001/p = 0.001, p = 0.009/p = 0.020) relative to baseline. The NTP decrease in PH group was significantly higher than that in US group (1.84 ± 1.46 vs. 0.72 ± 1.45; p = 0.01). Pain intensity at rest (p = 0.001) and NPDI scores (p = 0.001) were statistically improvement in only PH group. EMLA cream phonophoresis is more effective than conventional ultrasound therapy in terms of pain and associated neck disability, and it seems the complementary treatment option for MPS.

journal_name

Rheumatol Int

authors

Ustun N,Arslan F,Mansuroglu A,Inanoglu D,Yagız AE,Guler H,Turhanoglu AD

doi

10.1007/s00296-013-2881-2

subject

Has Abstract

pub_date

2014-04-01 00:00:00

pages

453-7

issue

4

eissn

0172-8172

issn

1437-160X

journal_volume

34

pub_type

杂志文章,随机对照试验
  • Systemic necrotizing vasculitides in Turkey: a comparative analysis of 40 consecutive patients.

    abstract:OBJECTIVE:The aim of this study was to analyze and compare the demographic and clinical features and prognosis of patients with different systemic necrotizing vasculitides (SNV) in Turkey. PATIENTS AND METHODS:Twenty-three patients with Wegener's granulomatosis (WG), 15 with polyarteritis nodosa (PAN), and two with Ch...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-004-0499-0

    authors: Kamali S,Inanc M,Gul A,Ocal L,Polat NG,Kilicaslan I,Aral O,Konice M

    更新日期:2005-11-01 00:00:00

  • The role of genetics and epigenetics in rheumatic diseases: are they really a target to be aimed at?

    abstract::To date, numerous genetic and epigenetic studies have been performed and provided a crucial step forward in our understanding of the pathogenesis of rheumatic diseases. However, most of the recent advances in the treatment of rheumatic diseases including biological therapies are not based on or even discrepant from th...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-018-4026-0

    authors: Kato M,Yasuda S,Atsumi T

    更新日期:2018-08-01 00:00:00

  • Clinical significance of rheumatoid factor isotypes in seropositive arthritis.

    abstract::In this cross-sectional study a comparison was made of rheumatoid factor (RF) isotypes in 203 RF positive patients with arthritis. Of these, 129 had rheumatoid arthritis (RA) and 74 a milder disease that would formerly have been classified as probable RA. The majority (74%) of the RA patients had elevations of two or ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00290265

    authors: Jónsson T,Valdimarsson H

    更新日期:1992-01-01 00:00:00

  • Atrioventricular conduction time in rheumatoid arthritis.

    abstract::The atrioventricular conduction time (P-R interval) was determined in 189 women and 90 men with rheumatoid arthritis (RA). Only three women and one man were found to have pathological prolongation of the P-R interval. However, a significant prolongation of the P-R interval, within normal range, was seen in women with ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541337

    authors: Jurik AG,Møller P

    更新日期:1985-01-01 00:00:00

  • Drug-induced lupus in anti-TNF-alpha therapy and its treatment with rituximab.

    abstract::We report three patients with rheumatoid arthritis (RA) who were treated with anti-TNF-α agents and who developed drug-induced lupus (DIL). Two of them received etanercept and the remainder adalimumab. We also present the favorable response observed with the withdrawal of the anti-TNF-alpha agents and the introduction...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-011-2137-y

    authors: Diaz JC,Vallejo S,Cañas CA

    更新日期:2012-10-01 00:00:00

  • Current concepts in the pathophysiology of fibromyalgia: the potential role of oxidative stress and nitric oxide.

    abstract::Fibromyalgia (FM) is a common chronic pain syndrome with an unknown etiology. Recent years added new information to our understanding of FM pathophysiology. Researches on genetics, biogenic amines, neurotransmitters, hypothalamic-pituitary-adrenal axis hormones, oxidative stress, and mechanisms of pain modulation, cen...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-005-0078-z

    authors: Ozgocmen S,Ozyurt H,Sogut S,Akyol O

    更新日期:2006-05-01 00:00:00

  • Bone mineral density is decreased in fibromyalgia syndrome: a systematic review and meta-analysis.

    abstract::Previous studies have shown that fibromyalgia syndrome (FMS) is associated with low level of physical activity and exercise, which may lead to an increased risk of osteoporosis. However, studies of bone mineral density (BMD) in fibromyalgia have shown conflicting results. Thus, we conducted a systematic review and met...

    journal_title:Rheumatology international

    pub_type: 杂志文章,meta分析,评审

    doi:10.1007/s00296-016-3625-x

    authors: Upala S,Yong WC,Sanguankeo A

    更新日期:2017-04-01 00:00:00

  • Microscopic polyangiitis complicated with bilateral brachial plexopathy: a case report and review of the literature.

    abstract::Microscopic polyangiitis is a small-vessel necrotizing vasculitis associated with anti-neutrophil cytoplasmic antibodies and presents itself with glomerulonephritis and hemorrhagic pulmonary capillaritis. Peripheral nervous system involvement is common in anti-neutrophil cytoplasmic antibodies-associated vasculitis, b...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-016-3424-4

    authors: Naseri Alavi SA,Meshkini M,Pourlak T,Khabbazi A

    更新日期:2016-07-01 00:00:00

  • CT assessment of axillary lymphadenopathy in patients with rheumatoid arthritis: association with disease activity and severity.

    abstract:BACKGROUND:Axillary lymph nodes (ALNs) are often seen on chest computed tomography (CT) in rheumatoid arthritis (RA) patients. Early reports described lymphadenopathy as one of the systemic manifestations rather than regional lymphadenopathy secondary to drainage from the affected joints. Subsequently, the importance o...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-018-3992-6

    authors: Hasegawa M,Sakai F,Konda N,Okabayashi A,Katsura H,Seto Y

    更新日期:2018-06-01 00:00:00

  • TGF-β signal transduction pathways and osteoarthritis.

    abstract::Osteoarthritis (OA) is the most common form of arthritis, resulting in substantial disability and economic burden worldwide. While its exact pathogenesis remains elusive, both in vitro and human population-based studies have merged to support the hypothesis that TGF-β/BMP-mediated signalling pathways play a role in th...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-015-3251-z

    authors: Zhai G,Doré J,Rahman P

    更新日期:2015-08-01 00:00:00

  • Total oxidative/anti-oxidative status and relation to bone mineral density in osteoporosis.

    abstract::The aim of this study was to evaluate the total antioxidant status (TAS), total oxidative status (TOS) and oxidative stress index (OSI) in patients with postmenopausal osteoporosis. We also investigate the relation between bone mineral density and oxidative/antioxidative parameters. Thirty-nine patients with osteoporo...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-007-0452-0

    authors: Altindag O,Erel O,Soran N,Celik H,Selek S

    更新日期:2008-02-01 00:00:00

  • The effects of the Mediterranean diet on rheumatoid arthritis prevention and treatment: a systematic review of human prospective studies.

    abstract::Rheumatoid arthritis is a progressive autoimmune disease characterised by severely swollen and painful joints. To compliment pharmacotherapy, people living with rheumatoid arthritis often turn to dietary interventions such as the Mediterranean diet. The aim of the present systematic review is to discuss the effects of...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-017-3912-1

    authors: Forsyth C,Kouvari M,D'Cunha NM,Georgousopoulou EN,Panagiotakos DB,Mellor DD,Kellett J,Naumovski N

    更新日期:2018-05-01 00:00:00

  • Activated T lymphocytes, rheumatoid factor and erythrocyte sedimentation rate assays in rheumatoid arthritis.

    abstract::Activated T lymphocytes (Ia+ T-cells) in peripheral blood are associated with immune stimulation. We found the percentages of these cells significantly increased in 95% of rheumatoid arthritis (RA) patients. Our studies showed no relation between the percentages of these cells in peripheral blood and concurrent erythr...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00272435

    authors: Bartfeld H,Dham C

    更新日期:1988-01-01 00:00:00

  • One-year direct costs of biological therapy in rheumatoid arthritis and its predictive factors: data from the Moroccan RBSMR registry.

    abstract::The aim of the study was to estimate the annual direct costs of biological therapies in rheumatoid arthritis (RA), and to establish possible factors associated with those costs. The main data source was the Moroccan registry of biological therapies in rheumatic diseases (RBSMR Registry). We included patients with avai...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-020-04762-7

    authors: Fellous S,Rkain H,Ahid S,Abouqal R,Tahiri L,Hmamouchi I,Achemlal L,El Bouchti I,El Maghraoui A,Ghozlani I,Hassikou H,Harzy T,Ichchou L,Mkinsi O,Niamane R,Bahiri R,Allali F

    更新日期:2021-01-02 00:00:00

  • Improvement in rheumatoid arthritis following application of an extracorporeal granulotrap column, G-1.

    abstract::Patients with rheumatoid arthritis (RA) showed significantly (P < 0.01) increased numbers of granulocytes in their peripheral blood compared with normal donors and patients with osteoarthritis, and this finding correlated with interleukin-6 and C-reactive protein levels and active joint score. Then, 17 patients with R...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00290518

    authors: Fujimori J,Yoshino S,Koiwa M,Hirai H,Shiga H,Hayama N,Iino Y

    更新日期:1996-01-01 00:00:00

  • Cardiovascular risk in patients with rheumatoid arthritis: assessment of several traditional risk parameters and a German risk score model.

    abstract::The present cross-sectional data demonstrate cardiovascular (CV) risk in patients with rheumatoid arthritis (RA). The cross-sectional data were part of an interventional trial that included 100 patients with defined RA. Traditional CV risk parameters and risk score calculation for the German population were used to as...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-011-2238-7

    authors: Willers J,Hahn A

    更新日期:2012-12-01 00:00:00

  • The effects of exercise on lipid profile in systemic lupus erythematosus and healthy individuals: a randomized trial.

    abstract::The aim of the present study was to evaluate the effects of an exercise training program on lipid profile and composition of high-density lipoprotein (HDL) subfractions in systemic lupus erythematosus (SLE) patients and healthy controls. A 12-week, randomized trial was conducted. Thirty-three physically inactive SLE p...

    journal_title:Rheumatology international

    pub_type: 杂志文章,随机对照试验

    doi:10.1007/s00296-014-3081-4

    authors: Benatti FB,Miossi R,Passareli M,Nakandakare ER,Perandini L,Lima FR,Roschel H,Borba E,Bonfá E,Gualano B,de Sá Pinto AL

    更新日期:2015-01-01 00:00:00

  • Different genetic effect of PXK on systemic lupus erythematosus in the Korean population.

    abstract::PXK was identified as a novel candidate gene for systemic lupus erythematosus (SLE) from genome-wide association studies (GWAS) in Caucasians. But a recent replication study in Hong Kong Chinese reported that PXK was not associated with SLE. The aim of this study was to determine whether PXK is associated with SLE in ...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1789-3

    authors: Kim EM,Bang SY,Kim I,Shin HD,Park BL,Lee HS,Bae SC

    更新日期:2012-01-01 00:00:00

  • Early arthritis clinic is effective for rheumatoid and psoriatic arthritides.

    abstract:INTRODUCTION:Early arthritis clinics (EACs) have been well established since 1980s. Most of the data for their effectiveness comes from rheumatoid arthritis (RA) management and is largely limited to process outcomes. There is little evidence that such clinics improve clinical outcomes particularly for psoriatic arthrit...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-019-04253-4

    authors: Nisar MK

    更新日期:2019-04-01 00:00:00

  • Detection of anti-bovine beta 2-glycoprotein I antibody in sera from patients with antiphospholipid syndrome.

    abstract::We studied and characterized anti-bovine beta 2-glycoprotein I antibodies (aB beta 2-GPI) in sera from patients with antiphospholipid syndrome (APS) by ELISA. Bovine beta 2-glycoprotein I (beta 2-GPI) was purified by heparin affinity and DEAE ion-exchange chromatography, and identified on immunoblots using a monoclona...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00286762

    authors: Nomura M,Okada J,Kondo H

    更新日期:1995-01-01 00:00:00

  • Accuracy, completeness and accessibility of online information on fibromyalgia.

    abstract::Fibromyalgia is a multi-factorial illness primarily characterised by widespread chronic pain and fatigue, with several symptoms and associated conditions. Due to a lack of clinical awareness and an absence of objective diagnostic measures, fibromyalgia patients often engage with online health information. The aim is t...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-019-04265-0

    authors: Basavakumar D,Flegg M,Eccles J,Ghezzi P

    更新日期:2019-04-01 00:00:00

  • Altered thiol status in patients with rheumatoid arthritis.

    abstract::The thiol status of patients with rheumatoid arthritis is significantly different from that of controls. Plasma thiol levels are lower, albumin thiol reactivity is altered and intracellular thiol levels measured after hemoglobin precipitation are increased. These variations correlate with other indices of disease seve...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/BF00541162

    authors: Banford JC,Brown DH,Hazelton RA,McNeil CJ,Smith WE,Sturrock RD

    更新日期:1982-01-01 00:00:00

  • Fifteen-year trend in information on the World Wide Web for patients with rheumatoid arthritis: evolving, but opportunities for improvement remain.

    abstract::The aim of this study was to assess the changes in the characteristics of rheumatoid arthritis information on the Internet over a 15-year period and the positioning of Web sites posted by universities, hospitals, and medical associations. We replicated the methods of a 2001 study assessing rheumatoid arthritis informa...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-016-3507-2

    authors: Castillo-Ortiz JD,de Jesus Valdivia-Nuno J,Ramirez-Gomez A,Garagarza-Mariscal H,Gallegos-Rios C,Flores-Hernandez G,Hernandez-Sanchez L,Brambila-Barba V,Castaneda-Sanchez JJ,Barajas-Ochoa Z,Suarez-Rico A,Sanchez-Gonzalez JM,Ramos-

    更新日期:2016-09-01 00:00:00

  • Knowledge of features of inflammatory back pain in primary care in the West Midlands: a cross-sectional survey in the United Kingdom.

    abstract:KEY MESSAGES:There is a relative lack of confidence among GPs in the assessment and management of IBP vs. mechanical back pain. A simple screening tool for SpA, applicable in primary care urgently needs to be developed. It is reasonable for patients with symptoms suggestive of inflammatory back pain to be referred to s...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-018-4058-5

    authors: Adizie T,Elamanchi S,Prabu A,Pace AV,Laxminarayan R,Barkham N

    更新日期:2018-10-01 00:00:00

  • Posterior reversible encephalopathy during an attack of familial Mediterranean fever.

    abstract::Reported here is a 19-year-old female patient with familial Mediterranean fever who was seen for altered mental status and seizures. She was eventually diagnosed to have posterior reversible leukoencephalopathy syndrome. Although a variety of conditions have been reported in association with this syndrome, to our best...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-010-1388-3

    authors: Ulaşlı AM,Kutlu G,Kocatürk Ö,Özçakar L

    更新日期:2012-06-01 00:00:00

  • Tongue infarction as first symptom of temporal arteritis.

    abstract::Giant cell arteritis (GCA) is the most common systemic vasculitis affecting people over 50 years. This disease is a diagnostic challenge with a range of clinical symptoms and findings due to different affected vessels. Because of this, the initial diagnosis can be tricky, and some of the patients present at first time...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-009-1355-z

    authors: Husein-Elahmed H,Callejas-Rubio JL,Rios-Fernández R,Ortego-Centeno N

    更新日期:2012-03-01 00:00:00

  • The effect of coffee, tea, and caffeine consumption on serum uric acid and the risk of hyperuricemia in Korean Multi-Rural Communities Cohort.

    abstract::Caffeine, a commonly consumed food constituent, is known to exert beneficial physiological effects in humans. There is a lack of comprehensive population data for the effects of caffeine intake on urate metabolism. Therefore, the aim of this study was to determine whether coffee, tea, and caffeine intake influences se...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-014-3061-8

    authors: Bae J,Park PS,Chun BY,Choi BY,Kim MK,Shin MH,Lee YH,Shin DH,Kim SK

    更新日期:2015-02-01 00:00:00

  • High frequency of inflammatory back pain and other features of spondyloarthritis in patients with rheumatoid arthritis.

    abstract::The aim of this study was to investigate the frequency of patients with rheumatoid arthritis (RA) who have inflammatory back pain (IBP) and meet the existing classification criteria for ankylosing spondylitis (AS) and spondyloarthritis (SpA). We included 167 patients fulfilling the ACR 1987 revised criteria for RA. Af...

    journal_title:Rheumatology international

    pub_type: 杂志文章

    doi:10.1007/s00296-012-2553-7

    authors: Can G,Solmaz D,Binicier O,Akar S,Birlik M,Soysal O,Akkoc N,Manisali M,Onen F

    更新日期:2013-05-01 00:00:00

  • Report of anti-CCP antibody positive paraneoplastic polyarthritis and review of the literature.

    abstract::A 45-year-old female presented to the rheumatology clinic with complaint of pain and swelling of multiple small joints of the hands and feet. She also complained of cough and shortness of breath onset around the same time. Since her cyclic citrullinated peptide antibody (anti-CCP) and rheumatoid factor tests were posi...

    journal_title:Rheumatology international

    pub_type: 杂志文章,评审

    doi:10.1007/s00296-009-1294-8

    authors: Larson E,Etwaru D,Siva C,Lawlor K

    更新日期:2011-12-01 00:00:00

  • Infliximab biosimilar CT-P13 therapy in patients with Takayasu arteritis with low dose of glucocorticoids: a prospective single-arm study.

    abstract::To evaluate the efficacy and safety of infliximab biosimilar CT-P13 in patients with active Takayasu arteritis (TAK). In this single-center open-label trial, patients with active TAK received CT-P13 at a starting dose of 5 mg/kg at weeks 0, 2, 6, and then every 8 weeks up to week 46. They were followed up until week 5...

    journal_title:Rheumatology international

    pub_type: 临床试验,杂志文章

    doi:10.1007/s00296-018-4159-1

    authors: Park EH,Lee EY,Lee YJ,Ha YJ,Yoo WH,Choi BY,Paeng JC,Suh HY,Song YW

    更新日期:2018-12-01 00:00:00