Abstract:
:Previous studies have shown that fibromyalgia syndrome (FMS) is associated with low level of physical activity and exercise, which may lead to an increased risk of osteoporosis. However, studies of bone mineral density (BMD) in fibromyalgia have shown conflicting results. Thus, we conducted a systematic review and meta-analysis to better characterize the association between FMS and BMD. A comprehensive search of the databases MEDLINE and EMBASE was performed from inception through May 2016. The inclusion criterion was the observational studies' assessment of the association between fibromyalgia and bone mineral density in adult subjects. Fibromyalgia was diagnosed in accordance with the American College of Rheumatology criteria for the diagnosis of fibromyalgia syndrome. BMD was measured at the lumbar spine and femoral neck by dual-energy X-ray absorptiometry. Pooled mean difference (MD) of BMD at each site and 95% confidence interval (CI) were calculated using a random-effect, generic inverse variance method. The between-study heterogeneity of effect size was quantified using the Q statistic and I 2. Data were extracted from four observational studies involving 680 subjects. At lumbar spine (L2-L4), BMD is significantly decreased in patients with FMS compared with controls with pooled MD of -0.02 (95% CI -0.03 to -0.01, P value = 0.003, I 2 = 0%) (Fig. 1). At femoral neck, BMD is not significantly decreased in patients with FMS compared with controls with pooled MD of 0.01 (95% CI -0.02 to 0.01, P value = 0.23, I 2 = 0%) (Fig. 2). In this meta-analysis, we observe that BMD at lumbar spine is decreased in FMS compared with normal individuals. Patients with FMS should be assessed for risk of osteoporosis. Fig. 1 Forest plot of bone mineral density at the lumbar spine, for patients with and without fibromyalgia syndrome. CI-confidence interval Fig. 2 Forest plot of bone mineral density at the femoral neck, for patients with and without fibromyalgia syndrome. CI-confidence interval.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Upala S,Yong WC,Sanguankeo Adoi
10.1007/s00296-016-3625-xsubject
Has Abstractpub_date
2017-04-01 00:00:00pages
617-622issue
4eissn
0172-8172issn
1437-160Xpii
10.1007/s00296-016-3625-xjournal_volume
37pub_type
杂志文章,meta分析,评审abstract::Patients with chronic thromboembolic pulmonary hypertension (CTEPH) have poor prognosis, and pulmonary endarterectomy (PEA) is considered the treatment of choice for this condition. We report a case and review the literature of successful PEA for CTEPH due to antiphospholipid syndrome associated with systemic lupus er...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-011-2346-4
更新日期:2013-07-01 00:00:00
abstract::The aim of the study is to determine the prevalence of and factors associated with major depression among those with Fibromyalgia Syndrome (FMS) in a Canadian representative sample. The study was a secondary analysis of a large, nationally representative sample from the Canadian Community Health Survey. The full sampl...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1713-x
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abstract::The objective of this study is to describe the interstitial lung disease (ILD) in rheumatoid arthritis (RA) patients of China, and to study clinical significance of high-resolution computed tomography (HRCT) in evaluation and treatment. One hundred and ten Chinese patients (79 women and 31 man) diagnosed with RA betwe...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1665-1
更新日期:2012-03-01 00:00:00
abstract::Sjogren's syndrome (SS) is a systemic autoimmune disease characterized by xerophthalmia, xerostomia and extraglandular manifestations. Anemia, leukopenia, thrombocytopenia and lymphoproliferative disorders, including lymphoma are well-known extraglandular, hematological complications of SS. We report here a rare case ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-010-1395-4
更新日期:2012-05-01 00:00:00
abstract::The aim of this study is to investigate whether eutectic mixture of local anesthetics (EMLA) cream phonophoresis superior to conventional US over the trigger points (TPs) in terms of improvements of pain, range of motion and disability in myofascial pain syndrome (MPS). Fifty patients (42 female, 8 male) diagnosed wit...
journal_title:Rheumatology international
pub_type: 杂志文章,随机对照试验
doi:10.1007/s00296-013-2881-2
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abstract::The aim of this study is to determine whether and to which extent pentosidine (PEN) is influenced in the case of advanced osteoarthritis (OA) in urine and in some tissues. Reverse phase HPLC method for PEN determination with fluorescence monitoring was utilized. Urinary pentosidine (U-PEN) and pyridinoline (U-PD) were...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-006-0105-8
更新日期:2006-08-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-016-3546-8
更新日期:2016-10-01 00:00:00
abstract::The Juvenile Arthritis Multidimensional Assessment Report (JAMAR) is a new parent/patient reported outcome measure that enables a thorough assessment of the disease status in children with juvenile idiopathic arthritis (JIA). We report the results of the cross-cultural adaptation and validation of the parent and patie...
journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
doi:10.1007/s00296-018-3964-x
更新日期:2018-04-01 00:00:00
abstract::Neuropathic arthropathy (NA), known as Charcot neuroarthropathy, is a chronic, degenerative arthropathy and is associated with decreased sensory innervation. Numerous causes of this arthropathy have been described. Neuropathic joint, although first described by Charcot in tabes dorsalis in 1868, has subsequently been ...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1013-5
更新日期:2010-05-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-015-3397-8
更新日期:2016-04-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-020-04633-1
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abstract:AIM:The aim of this study was to assess the efficacy of long-term azathioprine and steroids for treatment of severe nephritis in children with Henoch-Schönlein purpura (HSP). METHODS:Analysis of case records of children with HSP followed up for a mean duration of 4.7 years (range 6 months-6.5 years) was performed. All...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-002-0208-9
更新日期:2002-08-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s002960000063
更新日期:2000-12-01 00:00:00
abstract::Cutaneous leukocytoclastic vasculitis (CLV) is a small-vessel vasculitis localized to the skin. Many possible causes exist for this pathological condition, including drugs, infection, collagen vascular disease, and malignancy. However, Mycobacterium tuberculosis is rarely reported to be associated with CLV. Here, we r...
journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-006-0152-1
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-014-3197-6
更新日期:2015-03-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-020-04762-7
更新日期:2021-01-02 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2902-1
更新日期:2014-03-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-011-1866-2
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journal_title:Rheumatology international
pub_type: 杂志文章
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-019-04496-1
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journal_title:Rheumatology international
pub_type: 杂志文章
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更新日期:2020-06-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0685-6
更新日期:2008-10-01 00:00:00
abstract::The exact elucidation of skeletal and cartilagineous involvement in neonatal-onset multisystem inflammatory disease (NOMID) is still poorly known, and there are few data providing the long-term response to treatment with the available interleukin-1 inhibitors. We present here a 13-year-old boy with NOMID treated with ...
journal_title:Rheumatology international
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doi:10.1007/s00296-010-1787-5
更新日期:2011-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-009-1139-5
更新日期:2010-08-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-017-3748-8
更新日期:2017-08-01 00:00:00
abstract::The aim of this study was to investigate the percentage of regulatory T cells and the correlation with clinical activity in Behçet's disease. Forty Behçet's disease (BD) patients, 18 males and 22 females, were included in the study. The patients were diagnosed according to the published BD criteria. Twenty age- and se...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-013-2835-8
更新日期:2013-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,多中心研究
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更新日期:2014-12-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,评审
doi:10.1007/s00296-020-04620-6
更新日期:2020-08-01 00:00:00
abstract::Although several effects of electromagnetic fields (EMFs) on articular cartilage have been reported in recent studies, the use of EMFs to treat osteoarthritis remains a matter of debate. In an in vitro study, human chondrocytes harvested from osteoarthritic knee joints were released from their surrounding matrix and t...
journal_title:Rheumatology international
pub_type: 杂志文章
doi:10.1007/s00296-008-0565-0
更新日期:2008-08-01 00:00:00
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journal_title:Rheumatology international
pub_type: 杂志文章,随机对照试验
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更新日期:2011-10-01 00:00:00