Abstract：
:The aim of this study is to determine whether and to which extent pentosidine (PEN) is influenced in the case of advanced osteoarthritis (OA) in urine and in some tissues. Reverse phase HPLC method for PEN determination with fluorescence monitoring was utilized. Urinary pentosidine (U-PEN) and pyridinoline (U-PD) were determined in the group (N=67, age 67.1+/-11.7 years) in patients with OA before and after surgery (knee or hip replacement), and in healthy age-matched controls (N=18, age 67.0+/-6.0 years). Cartilage, synovial membrane and granulation tissue were also treated. In OA group significantly higher (P<0.001) U-PEN concentrations before (7.5+/-5.1 nmol/mmol creat.) and after (4.9+/-2.6 nmol/mmol creat.) surgery were found. U-PD was not significantly different between the groups (62.5+/-33.0 and 55.0+/-29.51 nmol/mmol creat., respectively), but differed significantly (P<0.0002 and P<0.01) from healthy subjects (40.2+/-16.5 nmol/mmol creat.). In the newly formed granulation tissue, PEN concentrations are significantly lower than in cartilage and in synovial tissues.
journal_name
Rheumatol Intjournal_title
Rheumatology internationalauthors
Spacek P,Adam Mdoi
10.1007/s00296-006-0105-8subject
Has Abstractpub_date
2006-08-01 00:00:00pages
923-7issue
10eissn
0172-8172issn
1437-160Xjournal_volume
26pub_type
杂志文章abstract：:Biological markers of inflammation are useful for the diagnosis and monitoring of inflammatory rheumatic diseases. The present study tested, whether serum amyloid A (SAA) could be used as a marker of inflammatory disease activity in ankylosing spondylitis (AS). In 72 patients with AS, the two valuable surrogate marker...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s002960050114
更新日期：2000-01-01 00:00:00
abstract：:During the coronavirus disease-2019 (COVID-19) pandemic there were several barriers to treatment access and medication adherence in rheumatoid arthritis (RA) patients. There is no information regarding the RA patient health status in Egypt during the COVID-19. Thus,the aim of this work was to study the impact of the p...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04736-9
更新日期：2021-02-01 00:00:00
abstract：:CD4(+) T cells from patients with systemic lupus erythematosus (SLE) exhibit increased expression of various proteins contributing to defective function of CD4(+) T cells. We evaluated the transcript and protein levels of perforin (PRF1) in CD4(+) T cells from SLE patients (n = 41) and healthy individuals (n = 34). Th...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1329-1
更新日期：2010-11-01 00:00:00
abstract：:This study investigated the prevalence of antibody against annexin II (A2) in patients with antiphospholipid syndrome (APS) and systemic lupus erythematosus (SLE). It also explored the role of this antibody in thrombosis. Purified recombinant A2 was used in ELISA to measure the levels of IgG anti-A2 antibody in 101 AP...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1379-4
更新日期：2011-07-01 00:00:00
abstract：:To investigate the efficacy of etanercept and MTX (methotrexate) combination therapy in Chinese patients with ankylosing spondylitis hip joint lesion, the possible courses and maintenance protocol, altogether 97 ankylosing spondylitis patients fulfilling the modified New York criteria with hip joint lesion were enroll...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1844-8
更新日期：2012-06-01 00:00:00
abstract：:The objective of this study was to report 11 cases of propylthiouracil (PTU)-induced autoimmune syndromes. We describe the clinical presentation, course, and outcome of 11 patients and compare clinical features between PTU-induced lupus and PTU-induced vasculitis. Of our 11 patients, 7 patients had vasculitis and 4 pa...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-010-1675-z
更新日期：2012-03-01 00:00:00
abstract：:The aim of the study was to assess agreement between three-dimensional volumetric ultrasound (3D US) performed by inexperienced staff and real-time conventional ultrasound (2D US) performed by experienced rheumatologists in detecting and scoring rheumatoid arthritis (RA) lesions. Thirty-one RA patients underwent exami...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3606-0
更新日期：2017-02-01 00:00:00
abstract：:Nitric oxide (NO) is a free radical that plays important roles in many physiological and pathological processes. Evidence suggests that NO participates in the pathogenesis of inflammatory reactions in many autoimmune and inflammatory diseases such as rheumatoid arthritis (RA). The purpose of this study was to evaluate...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002960100105
更新日期：2001-05-01 00:00:00
abstract：:There are contradictory results in the relevant literature about the relationship between objective determinants of craniocervical posture and temporomandibular disorder (TMD), whereas no study has worked on ankylosing spondylitis (AS) and TMD relationship. We conducted this study to test the predictors of TMD in AS p...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-020-04563-y
更新日期：2020-06-01 00:00:00
abstract：:Abnormal manifestations of central nervous system in system lupus erythematosus (SLE) patients are mainly caused by primary neuropsychiatric SLE (NP-SLE). We reported a new onset SLE patient who had secondary neuropsychiatric manifestations caused by Epstein-Barr virus (EBV) encephalitis. Although EBV has an uncertain...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-011-1877-z
更新日期：2012-08-01 00:00:00
abstract：:We assess the usefulness of 99mTc-pertechnetate hand perfusion scintigraphy in patients with Raynaud's phenomenon (RP). The study population consisted of 18 patients with primary RP, 25 patients with secondary RP within systemic sclerosis (SSc), and ten healthy individuals. Gamma camera dynamic first-pass study during...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3584-2
更新日期：2016-12-01 00:00:00
abstract：:Sound epidemiological data are a basic requirement for decision making on the allocation of health care resources. Unfortunately, this is not the case in Estonia, where the paucity of epidemiological data has impeded health care planning for rheumatic conditions. The current paper presents the first effort to explore ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2473-6
更新日期：2013-04-01 00:00:00
abstract：:We report a case of an association of four autoimmune diseases in a 15-year-old girl and we discuss the etiopathogenic of this association and difficulties of treatment. ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-0988-2
更新日期：2010-04-01 00:00:00
abstract：:The aim of this study was to evaluate whether cyclosporin A (CsA) influences the radiological disease progression in early rheumatoid arthritis (RA) patients in comparison with other disease-modifying drugs (DMARDs). A total of 103 early RA patients, without prior use of DMARDs, were randomized to receive CsA (3 mg/kg...
journal_title：Rheumatology international
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1007/s002960050113
更新日期：2000-01-01 00:00:00
abstract：:Rheumatoid arthritis (RA) is a multifactorial disease. A combination of genetic and environmental risk factors contributes to its etiology. Several genes have been reported to be associated with susceptibility to the development of RA. The MHC2TA and FCRL3 genes have been associated previously with RA in Swedish and J...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-015-3358-2
更新日期：2016-02-01 00:00:00
abstract：:The objectives of this study are to describe appropriateness and drug treatment of comorbidities in fibromyalgia (FM). Cross-sectional study of a group of patients. Number of drugs, indication, duration and appropriateness of prescriptions were evaluated. Patients were classified as: group 1, (FM/FM) previous FM diagn...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-016-3568-2
更新日期：2016-12-01 00:00:00
abstract：:Activated T lymphocytes (Ia+ T-cells) in peripheral blood are associated with immune stimulation. We found the percentages of these cells significantly increased in 95% of rheumatoid arthritis (RA) patients. Our studies showed no relation between the percentages of these cells in peripheral blood and concurrent erythr...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00272435
更新日期：1988-01-01 00:00:00
abstract：:To investigate whether the hypothermia induced by Adenosine 5'-Monophosphate (5'-AMP) could attenuate early stage injury in a rat acute gouty arthritis model. Ankle joint injection with monosodium urate monohydrate crystals (MSU crystals) in hypothermia rat model which was induced by 5'-AMP and then observe whether hy...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2676-5
更新日期：2013-08-01 00:00:00
abstract：:Immunofluorescence on polymorphonuclear cells (PMN) of patients with Felty syndrome (FS) revealed increased amounts of IgG, IgA, and IgM bound to the PMN surface compared with PMN of patients with rheumatoid arthritis alone. A positive correlation was found between the score for surface-bound immunoglobulins on FS-PMN...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00541352
更新日期：1985-01-01 00:00:00
abstract：:Behçet's disease (BD) commonly presents with articular manifestations and thrombotic vasculopathy. Arthritis of BD characteristically demonstrates a recurrent and nondestructive course. The pathobiological basis of the thrombotic vasculopathy and protective factors against cartilage destruction in arthritis of BD have...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-003-0324-1
更新日期：2004-03-01 00:00:00
abstract：:We aimed to investigate the diagnostic significance of high frequency ultrasonography (USG), comparing the findings in USG, bone scintigraphy and clinical stuation. Fifty-one patients who had early symptoms of inflammatory arthritis, but not fulfilling the ACR diagnostic criteria for rheumatoid arthritis (RA) were inc...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-008-0765-7
更新日期：2009-05-01 00:00:00
abstract：:Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily involving the spine and sacroiliac joint and rarely the kidneys. This study aimed to define the clinical and histological features and biology of renal disease in AS. We reviewed the medical records of 681 patients diagnosed with AS from November ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-012-2624-9
更新日期：2013-07-01 00:00:00
abstract：:This study aims to elucidate plasma oxidant/antioxidant status in patients with rheumatoid arthritis (RA). Fasting blood samples were obtained from 24 patients with RA and 20 control subjects. Antioxidant potential (AOP) value, nonenzymatic superoxide radical scavenger activity (NSSA), and malondialdehyde (MDA) levels...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s002960050097
更新日期：1999-01-01 00:00:00
abstract：:The objective of the study was to investigate the possibility whether the in vitro treatment with vitamin D3 can restore the impaired expression of protein kinase C (PKC) isoenzymes and IL-2 production in the lymphocytes of patients with systemic lupus erythematosus (SLE). Purified T lymphocytes from 14 patients with ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-013-2751-y
更新日期：2014-05-01 00:00:00
abstract：:Secondary amyloidosis is a well-known complication of certain familial Mediterranean fever (FMF). We presented three Turkish patients with FMF and biopsy proven amyloidosis. These patients were treated with colchicine 1.5 mg/day. They have experienced five to six peritonitis attacks with fever within 1 year. On admiss...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-006-0188-2
更新日期：2006-12-01 00:00:00
abstract：:Polyarteritis nodosa (PAN) related to hepatitis B is an uncommon vasculitis that is sometimes associated with the rapid progression of distal ischemia. A few recent reports have proposed the use of antiviral therapy. However, there is not yet a consensus for the standard treatment of this disease entity and none of th...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-006-0103-x
更新日期：2006-08-01 00:00:00
abstract：:Rheumatoid arthritis is a progressive autoimmune disease characterised by severely swollen and painful joints. To compliment pharmacotherapy, people living with rheumatoid arthritis often turn to dietary interventions such as the Mediterranean diet. The aim of the present systematic review is to discuss the effects of...
journal_title：Rheumatology international
pub_type： 杂志文章,评审
doi：10.1007/s00296-017-3912-1
更新日期：2018-05-01 00:00:00
abstract：:A total of 300 consecutive patients referred to a tertiary-care center and fulfilling the American Rheumatism Association criteria for definite-classical rheumatoid arthritis, (with a mean disease-duration of 10.3 +/- 9 years) were studied by structured interview and medical record review. The type of onset (rapid or ...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/BF00270365
更新日期：1987-01-01 00:00:00
abstract：:Osteopoikilosis, a form of osteosclerotic disorders, is a rare bone dysplasia with typical radiologic findings. The pathology, which sometimes requires attention in differential diagnosis due to its radiologic appearance, has been reported previously with other diseases. In this report, a case diagnosed with both reac...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-005-0037-8
更新日期：2006-05-01 00:00:00
abstract：:Regional migratory osteoporosis (RMO) is an idiopathic disorder characterized by severe periarticular pain, transient and migratory arthralgia, and osteoporosis. Osteoporosis in this disease may appear in the form of local regional osteoporosis and bone marrow edema or generalized osteoporosis. It occurs most commonly...
journal_title：Rheumatology international
pub_type： 杂志文章
doi：10.1007/s00296-009-1256-1
更新日期：2011-10-01 00:00:00
