Abstract:
:Pharmacology as a modern science was introduced in China approximately 150 years ago, and has been used since then to study traditional Chinese medicine (TCM). Pharmacology has experienced its own development over this time and continues to provide new tools for the study of TCM. In the present review, three models for the pharmacological study of TCM are considered: (i) chemistry-focused study; (ii) target-directed study; and (iii) systems-biology-based study. These approaches correspond to recent developments in pharmacology, and in particular to new tools available to the field. Representative achievements and the pharmacological tools used to study TCM are reviewed. Pharmacology has played, and will continue to play, an indispensable role in elucidating the chemical basis, biological targets, and mechanisms of action of TCM medicines, and in developing a scientific basis for the theory of TCM.
journal_name
Trends Pharmacol Scijournal_title
Trends in pharmacological sciencesauthors
Liu X,Wu WY,Jiang BH,Yang M,Guo DAdoi
10.1016/j.tips.2013.09.004subject
Has Abstractpub_date
2013-11-01 00:00:00pages
620-8issue
11eissn
0165-6147issn
1873-3735pii
S0165-6147(13)00167-3journal_volume
34pub_type
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