Abstract:
:The taste reactivity (TR) test was devised as a method to obtain behavioural data in response to gustatory stimuli in neurologically impaired rats, incapable of voluntary feeding. Sapid solutions were infused through surgically implanted intraoral cannulae. Facial and motor responses corresponded well to known hedonic and aversive properties of tastes (e.g., sweet, bitter). TR testing has since proved effective as an adjunct to intake-based methods, in the psychopharmacology of ingestion in the normal rat. We developed a nonsurgical modification of the TR test, in which intact rats sampled stimuli voluntarily. The benzodiazepine receptor agonist midazolam (3.0 mg/kg, IP) was administered to rats first trained to consume a sweet 3% sucrose solution, and later tested with access to a bitter 0.01% quinine solution. Response were videotaped, and TR measures were scored during periods of noningestion using a frame-by-frame playback. Treatment increased ingestion and facilitated ingestive responses in accordance with published data for cannulated rats. Results support a two-component view of response palatability, in which treatment alters feeding motivation, increasing positive palatability and facilitating ingestion of both palatable and unpalatable stimuli.
journal_name
Physiol Behavjournal_title
Physiology & behaviorauthors
Gray RW,Cooper SJdoi
10.1016/0031-9384(95)00115-ysubject
Has Abstractpub_date
1995-11-01 00:00:00pages
853-9issue
5eissn
0031-9384issn
1873-507Xpii
0031-9384(95)00115-Yjournal_volume
58pub_type
杂志文章abstract::In this article, we report findings from behavioral and neuroendocrine experiments in rats under pharmacologically induced antipyretic conditions. Endpoints included emotional fever, body weight setpoint, and in situ corticotropin-releasing hormone mRNA (CRHmRNA) expression. Nine male Wistar rats were treated with ace...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(02)01002-8
更新日期:2003-03-01 00:00:00
abstract::Nicotine exposure during development can alter behavior in adulthood in mice. One route of nicotine administration that can mimic some of the dynamics of human smoking is administration of the drug to pregnant and nursing mice through the drinking water. It is critical to determine if nicotine administration has an im...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2010.08.021
更新日期:2010-12-02 00:00:00
abstract::It is not known whether lateralized olfactory sensitivity deficits are present in MS. Since projections from the olfactory bulb to the olfactory cortex are largely ipsilateral, and since both functional imaging and psychophysical studies suggest that the right side of the brain may be more involved in olfactory proces...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.10.017
更新日期:2017-01-01 00:00:00
abstract::17-β estradiol (E2) has been shown to modulate fear conditioning by influencing freezing behavior following re-exposure to either the conditioning context or a cue associated with shock. Fear-related behaviors other than freezing may be influenced differently by E2 replacement. Accordingly, the present study examined ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.04.030
更新日期:2014-05-28 00:00:00
abstract::The examples of "synergism" reported in the taste literature fit the common definition of the term but may merely reflect normal additivity in the taste system. That is, the perceived intensities of these "synergistic" mixtures exceed the sums of the perceived intensities of the unmixed taste components (addition of p...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(80)90066-9
更新日期:1980-06-01 00:00:00
abstract::Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) are adrenal androgens that have been associated with a sense of well-being in humans. We describe two experiments done to test the hypothesis that an increase in DHEA or DHEAS secretion is associated with the inclination to exercise using a hamst...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(99)00108-0
更新日期:1999-10-01 00:00:00
abstract::The present study investigated the role of the midbrain reticular formation (MRF) in the expression of opposing locomotor asymmetries elicited from the medial and lateral substantia nigra pars compacta (SNC). It was found that unilateral MRF lesions produced ipsiversive circling that was potentiated by amphetamine. La...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(85)90406-8
更新日期:1985-11-01 00:00:00
abstract::A large part of domestic food intake may be determined by retail food purchase behavior, and it is commonly believed that this may be significantly influenced by the shopper's state of food deprivation. In the present study, 198 subjects recruited just prior to shopping at a large supermarket completed questionnaires ...
journal_title:Physiology & behavior
pub_type: 临床试验,杂志文章
doi:10.1016/s0031-9384(96)00241-7
更新日期:1996-11-01 00:00:00
abstract::We examined the time course and sex differences of the glucocorticoid response to forced, moderate-intensity treadmill exercise in outbred laboratory house mice. Mice (n = 64 total) were divided into eight groups, each of four males and four females, which were run on a motorized treadmill at 1.0 km/h for either 0, 2,...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(97)00441-1
更新日期:1998-01-01 00:00:00
abstract::We used the hemagglutination test to investigate differences in the specific immune response to sheep red blood cells (SRBC) of female common voles living in matriarchal groups. The applied test proved to be a useful tool for studying the effect of the social environment on the immune response in small mammals. The re...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(00)00332-2
更新日期:2000-11-01 00:00:00
abstract:PURPOSE:To describe and evaluate behavioral models of binge-type eating. DATA IDENTIFICATION:Studies were identified using Medline and hand searches of bibliographies of identified articles. STUDY SELECTION:Isomorphic studies were selected that were judged to have some measure of construct validity. DATA EXTRACTION:...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2004.04.036
更新日期:2004-08-01 00:00:00
abstract::Syrian golden hamsters (Mesocricetus auratus) received bilateral lesions aimed at the ventromedial hypothalamus (VMH) or a sham lesion. In the first study, some of the animals in each surgical group were housed in standard sedentary conditions while others had free access to running wheels. The lesions produced a 30% ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(86)90324-0
更新日期:1986-01-01 00:00:00
abstract::To investigate brain substrates of spatial memory, neuronal expression of c-Fos protein was studied. Two groups of rats were trained in two spatial memory tasks in the Morris water maze, where the rats have to apply a reference memory rule or a working memory rule. In addition to the experimental groups, two control g...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/s0031-9384(03)00060-x
更新日期:2003-04-01 00:00:00
abstract::Measurement of plasma corticosterone is difficult because the handling associated with blood sampling from birds is stressful. The use of non-invasive means of measuring stress could help to alleviate this problem. It was considered that the accumulation of plasma corticosterone into the egg albumen could provide a no...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2008.07.001
更新日期:2008-10-20 00:00:00
abstract::Food preference and fish-attractive parameters were studied on 1000 15- to 18-month-old Nile crocodiles, using two-choice preference tests. All three experimental groups preferred live fish over dead fish and live chicks, while ground meat was the last choice. As for fish attractiveness, motion, freshness, size, color...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90489-b
更新日期:1991-07-01 00:00:00
abstract::Despite many previous studies on stiffness perception, few have investigated the exploratory procedures involved. This study evaluated whether stiffness range influences pressing movements and perception of force and displacement during stiffness discrimination tasks. Force and displacement data were obtained from 30 ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2016.05.022
更新日期:2016-09-01 00:00:00
abstract::There is a wide body of literature to suggest that sexual experience may influence androgen secretion in various species, in turn, androgens may also influence anxiety. We hypothesized that sexual experience may alter anxiety behavior and secretion of endogenous androgens. Experiment 1: anxiety behavior of rats with a...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2007.04.018
更新日期:2007-10-22 00:00:00
abstract::Alzheimer's disease (AD) is a neurodegenerative disorder, characterized by a progressive loss of cognitive function. Despite considerable progress, a complete description of the molecular pathology of this disease has yet to be elucidated. In this respect, the need for an animal model that develops some or all aspects...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/s0031-9384(01)00524-8
更新日期:2001-08-01 00:00:00
abstract::The functional effects of chronic administration of 60 mg kg-1 chloroquine or quinacrine given as daily intraperitoneal injections for 84 days on normal and denervated expansor secundariorum muscles, a smooth muscle from the wing of chicks wholly innervated by noradrenergic nerves, have been investigated. Administrati...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(93)90121-u
更新日期:1993-08-01 00:00:00
abstract::An analysis of the gross composition of milk in five inbred strains of mice (NZB, CBA/H, BALB/c, C57BL/6, XLII) was conducted for two different days during the lactating period (6th and 9th day after parturition). The quantity of milk and the concentration of proteins, lactose and lipids were measured. Results show a ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(87)90027-8
更新日期:1987-01-01 00:00:00
abstract::Although High Intensity Interval Training (HIIT) are being associated to increase cardiovascular and metabolic adaptation, there is controversy and limited information about the effects of HIIT on hippocampal oxidative stress, pro- and anti-inflammatory cytokines balance and neurotrophic status. Thus, this study evalu...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2017.10.027
更新日期:2018-02-01 00:00:00
abstract::The glucose antimetabolite 2-deoxy-D-glucose (2DG) reliably causes hyperphagia in rats, but has consistently proven ineffective in producing overeating in golden hamsters. It was hypothesized that hamsters do not overeat following 2DG administration because of unusually strong aversive effects of the drug in this spec...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(88)90136-9
更新日期:1988-01-01 00:00:00
abstract::The discovery that pleasant touch is coded by C-tactile fibers has generated considerable research interest and increased understanding of the skin as a channel for social information via cutaneous senses. However, no study has differentiated between the pleasant response to visual and tactile non-human stimulations. ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2017.12.022
更新日期:2018-03-01 00:00:00
abstract::Four groups of female golden hamsters were exposed to short photoperiods (SP, LD 10:14) for 4, 14, 20, or 27 weeks and tested for physiological markers (uterine weight and estrous cycles) and behavioral (lordosis, approach and aggressive behaviors) measures while in contact with a stud male. After behavioral testing, ...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(91)90078-3
更新日期:1991-08-01 00:00:00
abstract::The present experiments investigated gene expression in the amygdala following contingent taste/LiCl treatment that supports development of conditioned taste aversion (CTA). The use of whole genome chips and stringent data set filtering led to the identification of 168 genes regulated by CTA compared to non-contingent...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2011.11.001
更新日期:2012-02-28 00:00:00
abstract::Although cooperation represents a long-standing evolutionary puzzle, field studies on social carnivores have contributed greatly to our understanding of the selective forces favoring cooperative breeding. Despite these insights, our grasp of the proximate mechanisms facilitating cooperation in carnivores remains surpr...
journal_title:Physiology & behavior
pub_type: 杂志文章,评审
doi:10.1016/j.physbeh.2017.11.006
更新日期:2018-09-01 00:00:00
abstract::Mesolimbic dopamine plays a critical role in food-related reward processing and learning. The literature focuses primarily on the nucleus accumbens as the key dopaminergic target in which enhanced dopamine signaling is associated with reward. Here, we demonstrate a novel neurobiological mechanism by which dopamine tra...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/j.physbeh.2014.02.026
更新日期:2014-09-01 00:00:00
abstract::Young adult rats housed in the activity-wheel cages and fed only 1 hr daily, have ulcers in the glandular stomach and reveal immunodeficiency. The present study was attempted to investigate how to separate the ulceration and immunodeficiency in order to utilize the activity-stress (A-S) model as an animal model of the...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(83)90174-9
更新日期:1983-05-01 00:00:00
abstract::Using rats of the inbred BN and WAG strain, we tested the hypothesis that chronic dietary choline supplementation would especially affect the timing behavior of BN rats because of their lower cholinergic activity and their poor performance in aversively motivated learning and memory tasks. An apparent effect of chroni...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(92)90068-d
更新日期:1992-05-01 00:00:00
abstract::Guinea pig pups vocalized more and were more active during a 60-min period of isolation in a novel environment when injected SC with 50 micrograms of the corticotropin-releasing factor (CRF) antagonist, [D-Phe]CRF12-41, than when injected with saline vehicle only. More pups exhibited eye closing and extensive piloerec...
journal_title:Physiology & behavior
pub_type: 杂志文章
doi:10.1016/0031-9384(96)00091-1
更新日期:1996-09-01 00:00:00