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A report from Fukushima: an assessment of bone health in an area affected by the Fukushima nuclear plant incident.

Abstract：

:Bone health was assessed for inhabitants of an area affected by the Fukushima nuclear plant incident. Osteoporotic patients, who had been treated with active vitamin D3 and/or bisphosphonate at Soma Central Hospital before the Fukushima incident, were enrolled. Changes in bone turnover markers and bone mineral density were retrospectively analyzed. Serum levels of a bone resorption marker, serum type I collagen cross-linked N-telopeptide were decreased in all the treated groups, whereas those of a bone formation marker, bone-specific alkaline phosphatase, were increased. Accordingly, bone mineral density, estimated by dual-energy X-ray absorptiometry, was increased in the lumbar spine of all groups, but bone mass increase in the proximal femur was detected only in the group treated with the two agents in combination. From the degree of these parameter changes, the antiosteoporotic treatments looked effective and were equivalent to the expected potency of past observations. At this stage, the present study implies that the Fukushima nuclear incident did not bring an acute risk to bone health in the affected areas.

journal_name

J Bone Miner Metab

journal_title

Journal of bone and mineral metabolism

authors

Ishii T,Ito K,Kato S,Tsubokura M,Ochi S,Iwamoto Y,Saito Y

doi

10.1007/s00774-013-0482-5

subject

Has Abstract

pub_date

2013-11-01 00:00:00

pages

613-7

issue

6

eissn

0914-8779

issn

1435-5604

journal_volume

31

pub_type

杂志文章

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