Identification of a novel frameshift mutation (383insT) in the RUNX2 (PEBP2 alpha/CBFA1/AML3) gene in a Japanese patient with cleidocranial dysplasia.

abstract：:Osteoporosis is a serious public health problem, and dietary interventions may potentially be helpful in preventing this disorder. The purpose of this study was to determine the effects of a low sodium diet on bone metabolism in postmenopausal women. This was a longitudinal study to determine the effects of a low sodi...

journal_title：Journal of bone and mineral metabolism

authors： Carbone LD,Barrow KD,Bush AJ,Boatright MD,Michelson JA,Pitts KA,Pintea VN,Kang AH,Watsky MA

更新日期：2005-01-01 00:00:00

abstract：:Alendronate has recently been approved for the prevention and treatment of postmenopausal osteoporosis, and its efficacy has been demonstrated in many Western countries. Our present study was performed to evaluate the effect of alendronate on bone mineral density (BMD) and its tolerability in Thais. Eighty postmenopau...

journal_title：Journal of bone and mineral metabolism

authors： Chailurkit LO,Jongjaroenprasert W,Rungbunnapun S,Ongphiphadhanakul B,Sae-tung S,Rajatanavin R

更新日期：2003-01-01 00:00:00

abstract：:The purpose of this study was to investigate the relationship between intervertebral disk degeneration and bone mass. Magnetic resonance imaging was performed to evaluate lumbar disk degeneration according to Thompson's classification (grades 1 and 2, normal disk; grades 3, 4, and 5, degenerated disk), and bone minera...

journal_title：Journal of bone and mineral metabolism

authors： Nanjo Y,Morio Y,Nagashima H,Hagino H,Teshima R

更新日期：2003-01-01 00:00:00

abstract：:The dietary reference intake (DRI) of vitamin D for Korean children was reduced from 400 IU/day in 2005 to 200 IU/day in 2010. We evaluated the risk factors for low 25-hydroxyvitamin D [25(OH)D] status and its relationships with bone health in peripubertal nonobese children living in Seoul or Gyeonggi-do. One hundred ...

journal_title：Journal of bone and mineral metabolism

authors： Lee YA,Kim JY,Kang MJ,Chung SJ,Shin CH,Yang SW

更新日期：2013-05-01 00:00:00

abstract：:Low levels of vitamin D nutrition (i.e., vitamin D insufficiency), which potentially cause osteoporosis, have been recognized as a common health problem for elderly people in European and North American countries, but there have been no studies on the prevalence of vitamin D insufficiency in Japan until recently. The ...

journal_title：Journal of bone and mineral metabolism

authors： Nakamura K

更新日期：2006-01-01 00:00:00

abstract：:The impact of smoking on peak bone density has not been conclusively established. We examined how smoking exposure influences bone mineral density (BMD) or the risk of low bone status in premenopausal women. We conducted a baseline survey with a representative sample of Japanese women in 1996. The effect of current an...

journal_title：Journal of bone and mineral metabolism

authors： Tamaki J,Iki M,Sato Y,Kajita E,Kagamimori S,Kagawa Y,Yoneshima H

更新日期：2010-05-01 00:00:00

abstract：:We have previously demonstrated the efficacy of therapeutic exercise for osteoarthritis (OA) of the knee. This study was performed to examine the additive effects of glucosamine or risedronate on the exercise therapy. In this study, 142 female patients with moderate OA of the knee, who had been recommended to undergo ...

journal_title：Journal of bone and mineral metabolism

authors： Kawasaki T,Kurosawa H,Ikeda H,Kim SG,Osawa A,Takazawa Y,Kubota M,Ishijima M

更新日期：2008-01-01 00:00:00

abstract：:Osteoporosis is the most common bone disease in humans. During bone remodeling, specialized blood vessels influenced by the endothelial cells (CD31hiEmcnhi, also called type H cells) are formatted to supply nutrients. Reductions in vascular supply are associated with bone loss resulting in osteoporosis. Therefore, the...

journal_title：Journal of bone and mineral metabolism

authors： Zhu Y,Ruan Z,Lin Z,Long H,Zhao R,Sun B,Cheng L,Tang L,Xia Z,Li C,Zhao S

更新日期：2019-11-01 00:00:00

abstract：:The effects of catecholamine excess due to pheochromocytoma on body composition, including skeletal muscle mass, are unknown. Here, we investigated the effects of catecholamine metabolites on body composition in subjects with pheochromocytoma. After body compositions using bioelectrical impedance analysis, urinary met...

journal_title：Journal of bone and mineral metabolism

authors： Lee SH,Kwak MK,Ahn SH,Kim H,Cho YY,Suh S,Song KH,Koh JM,Kim JH,Kim BJ

更新日期：2019-07-01 00:00:00

abstract：:In end-stage osteoarthritis (OA) of the hip, the effect of bone metabolism with and without cartilage is unclear. In this study, we aimed to investigate histomorphology and microdamage in the subchondral bone of the femoral head in areas with and without articular cartilage in patients with end-stage OA. Nineteen femo...

journal_title：Journal of bone and mineral metabolism

authors： Shimamura M,Iwata K,Mashiba T,Miki T,Yamamoto T

更新日期：2019-09-01 00:00:00

abstract：:Secondary hyperparathyroidism (SHPT) develops as a compensatory mechanism when the body is in calcium deficit. SHPT may be harmful and has been associated with elevated blood pressure. The cause of SHPT could be low calcium intake, reduced intestinal calcium absorption, or increased excretion. However, the relative im...

journal_title：Journal of bone and mineral metabolism

authors： Saleh F,Jorde R,Sundsfjord J,Haug E,Figenschau Y

更新日期：2006-01-01 00:00:00

abstract：:Previously, we reported that millimeter wave promoted the chondrocyte proliferation by pushing cell cycle progression. Activation of K(+) channels plays an essential role in the stimulating of extracellular matrix (ECM) synthesis and the cell proliferation in chondrocytes. While it is unclear if millimeter wave enhanc...

journal_title：Journal of bone and mineral metabolism

authors： Li X,Liu C,Liang W,Ye H,Chen W,Lin R,Li Z,Liu X,Wu M

更新日期：2014-07-01 00:00:00

abstract：:Interleukin-11 (IL-11) is a bone marrow stromal fibroblast-derived cytokine with a wide spectrum of activities in different biological systems. IL-11 and IL-6 are two cytokines known to rely on osteoblast-osteoclast communication for their effects on osteoclast differentiation. Bone sialoprotein (BSP) is a mineralized...

journal_title：Journal of bone and mineral metabolism

authors： Matsumura H,Nakayama Y,Takai H,Ogata Y

更新日期：2015-03-01 00:00:00

abstract：INTRODUCTION:Etelcalcetide binds to the extracellular domain of the calcium-sensing receptor (CaSR), while cinacalcet binds to the 7-transmembrane domain of the CaSR; however, it is unknown, whether etelcalcetide has similar effects to cinacalcet on parathyroid hormone (PTH) secretion. MATERIALS AND METHODS:The PTH-ca...

journal_title：Journal of bone and mineral metabolism

authors： Hayashi N,Imanishi Y,Hirakawa T,Kobayashi I,Tateishi T,Miyaoka D,Nagata Y,Mori K,Morioka T,Inoue A,Harada K,Inaba M,Emoto M

更新日期：2020-11-16 00:00:00

abstract：:Bone mass differs according to ethnic classification, with individuals of African ancestry attaining the highest measurements across numerous skeletal sites. Elevated bone mass is even maintained in those individuals exposed to adverse environmental factors, suggesting a prominent genetic effect that may have clinical...

journal_title：Journal of bone and mineral metabolism

authors： May A,Pettifor JM,Norris SA,Ramsay M,Lombard Z

更新日期：2013-11-01 00:00:00

abstract：INTRODUCTION:Aromatase inhibitors are known to accelerate bone loss in patients with breast cancer. However, how much AIs affect the efficacy of antiresorptive agents has not been studied. The study aimed to compare the effect of alendronate on bone mineral density (BMD) between patients with and without AI treatment. ...

journal_title：Journal of bone and mineral metabolism

authors： Kong SH,Kim JH,Kim SW,Shin CS

更新日期：2020-09-01 00:00:00

abstract：:Osteoporosis is a systemic and metabolic bone disease. New drugs with good curative effect, fewer side effects, and high safety need to be developed urgently. Recently, simvastatin has been used to treat osteoporosis more frequently; however, its clinical effect and treatment mechanism are still unknown. With the use ...

journal_title：Journal of bone and mineral metabolism

authors： Dai L,Xu M,Wu H,Xue L,Yuan D,Wang Y,Shen Z,Zhao H,Hu M

更新日期：2016-01-01 00:00:00

abstract：:Patients who are diagnosed with osteoporosis and beginning treatment often discontinue their osteoporosis medication relatively early after the start of treatment because of their poor recognition of fracture risk and the asymptomatic nature of osteoporosis. In this study we aimed to assess adherence to treatment with...

journal_title：Journal of bone and mineral metabolism

authors： Gorai I,Tanaka Y,Hattori S,Iwaoki Y

更新日期：2010-03-01 00:00:00

abstract：:Bone health was assessed for inhabitants of an area affected by the Fukushima nuclear plant incident. Osteoporotic patients, who had been treated with active vitamin D3 and/or bisphosphonate at Soma Central Hospital before the Fukushima incident, were enrolled. Changes in bone turnover markers and bone mineral density...

journal_title：Journal of bone and mineral metabolism

authors： Ishii T,Ito K,Kato S,Tsubokura M,Ochi S,Iwamoto Y,Saito Y

更新日期：2013-11-01 00:00:00

abstract：:Syndecans are single-pass integral membrane components that serve as co-receptors for growth factors and cytokines and can elicit signal transduction via their cytoplasmic tails. We review here previous studies from our groups on syndecan-3 biology and function in the growth plates of developing long bones in chick an...

journal_title：Journal of bone and mineral metabolism

authors： Pacifici M,Shimo T,Gentili C,Kirsch T,Freeman TA,Enomoto-Iwamoto M,Iwamoto M,Koyama E

更新日期：2005-01-01 00:00:00

abstract：:There is a lack of research on volumetric multi-slice CT (MSCT) application in hip densitometric assessment and geometric measures in elderly women with osteoporotic vertebral fractures. A total of 237 elderly women were divided into three groups based on BMD values of the lumbar spine (AP-SPINE) and/or the femoral ne...

journal_title：Journal of bone and mineral metabolism

authors： Wu SY,Qi J,Lu Y,Lan J,Yu JC,Wen LQ,Zhang ZL

更新日期：2010-11-01 00:00:00

abstract：:This study aimed to identify the osteogenesis effect of icariside II (ICSII) and icaritin (ICT) in vitro. Bone marrow mesenchymal stem cells (BMSCs) were treated with ICSII and ICT in order to detect the proliferation and differentiation of BMSCs, the expression of the osteogenesis-related proteins with or without ost...

journal_title：Journal of bone and mineral metabolism

authors： Luo G,Xu B,Wang W,Wu Y,Li M

更新日期：2018-11-01 00:00:00

abstract：INTRODUCTION:Surgical treatment in patients with medication-related osteonecrosis of the jaw (MRONJ) is superior to conservative treatment. However, treatment outcome in patients with periosteal reaction (PR) was significantly poorer than that of those without PR. The purpose of this retrospective study was to analyze ...

journal_title：Journal of bone and mineral metabolism

authors： Soutome S,Yanamoto S,Sumi M,Hayashida S,Kojima Y,Sawada S,Rokutanda S,Iwai H,Saito T,Umeda M

更新日期：2020-10-12 00:00:00

abstract：:The aim of this study was to evaluate the prevalence of spine–femur discordance, and to compare the effectiveness of femoral neck (FN) and lumbar spine (LS) bone mineral density (BMD) for estimation of the risk of vertebral fractures. Women who were evaluated with dual energy X-ray absorptiometry between January 2001 ...

journal_title：Journal of bone and mineral metabolism

authors： Seok H,Kim KJ,Kim KM,Rhee Y,Cha BS,Lim SK

更新日期：2014-07-01 00:00:00

abstract：:Menin, a product of the MEN1 gene, is related to the ontogeny of several cancers such as MEN1 and sporadic endocrine tumors, although it is considered to be a tumor suppressor. Many proteins interact with menin, and it is involved in various biological functions in several tissues. Menin plays some physiological and p...

journal_title：Journal of bone and mineral metabolism

authors： Kaji H

更新日期：2012-07-01 00:00:00

abstract：:Simvastatin has been shown to stimulate osteogenesis both in vitro and in vivo. However, the mechanism by which simvastatin exerts its effects is still unclear. We previously reported that simvastatin promotes bone morphogenetic protein 2 (BMP-2) expression, induces osteoblastic differentiation, and inhibits adipocyti...

journal_title：Journal of bone and mineral metabolism

authors： Song C,Wang J,Song Q,Li X,Chen Z,Ma Q,Liu Z,Jia H,Dang G

更新日期：2008-01-01 00:00:00

abstract：:The prevalence and pattern of joint involvement in radiographic hand osteoarthritis (OA) have been reported in Western populations, but similar data are lacking for Japanese. We examined this issue in 551 Japanese women aged > or = 40 years. Radiographs were obtained of both hands and graded according to the Kellgren-...

journal_title：Journal of bone and mineral metabolism

authors： Toba N,Sakai A,Aoyagi K,Yoshida S,Honda S,Nakamura T

更新日期：2006-01-01 00:00:00

abstract：:In this study, we tested the interleukin-6 (IL-6) gene as an important candidate gene for its linkage and association with the variation of bone phenotypes (bone mineral density [BMD] and bone size) in young Chinese female subjects. We genotyped the IL-6 gene at the -634C/G restriction fragment length polymorphism (RF...

journal_title：Journal of bone and mineral metabolism

authors： Lei SF,Liu YZ,Deng FY,Li YM,Li MX,Deng HW

更新日期：2005-01-01 00:00:00

abstract：:Patients with MRI-proved acute painful vertebral fractures in whom conservative pain management fails are frequently referred for vertebroplasty. This study investigated the effects of treating osteoporosis on the mortality rate of patients with MRI-proved acute osteoporosis-related vertebral fractures who had undergo...

journal_title：Journal of bone and mineral metabolism

authors： Chen YC,Su FM,Cheng TT,Lin WC,Lui CC

更新日期：2016-05-01 00:00:00

abstract：:Data from retrospective and prospective observational and case-control studies suggest that activity is associated with reduced fracture risk, but consistently replicated bias may be responsible for this desired endpoint. Exercise during growth is likely to build a larger and stronger skeleton. However, cessation of e...

journal_title：Journal of bone and mineral metabolism

authors： Seeman E

更新日期：2005-01-01 00:00:00