Analysis of dynamic spectra in ferret primary auditory cortex. II. Prediction of unit responses to arbitrary dynamic spectra.

abstract：:The response properties of ampullary electroreceptors of paddlefish, Polyodon spathula, were studied in vivo, as single-unit afferent responses to external electrical stimulation with varied intensities of several types of noise waveforms, all Gaussian and zero-mean. They included broadband white noise, Ornstein-Uhlen...

journal_title：Journal of neurophysiology

authors： Neiman AB,Yakusheva TA,Russell DF

更新日期：2007-11-01 00:00:00

abstract：:1. The effects of gamma-aminobutyric acid (GABA) on non-GABAA receptors were investigated with intracellular recordings in CA1 pyramidal cells of rat hippocampal slices in the presence of antagonists of GABAA receptors (50 microM bicuculline and 50 microM picrotoxin), N-methyl-D-aspartate (NMDA) and non-NMDA receptors...

journal_title：Journal of neurophysiology

authors： Pham TM,Lacaille JC

更新日期：1996-07-01 00:00:00

abstract：:Task-dependent selectivity of movement-related neuronal activity in the primate prefrontal cortex. J. Neurophysiol. 80: 3392-3397, 1998. We studied movement-related neuronal activity in the dorsolateral prefrontal cortex from the perspective of a general role for the prefrontal cortex in controlling motor behavior to ...

journal_title：Journal of neurophysiology

authors： Hoshi E,Shima K,Tanji J

更新日期：1998-12-01 00:00:00

abstract：:Most of what we know about the neural control of gaze comes from experiments in head-fixed animals, but several "head-free" studies have suggested that fixing the head dramatically alters the apparent gaze command. We directly investigated this issue by quantitatively comparing head-fixed and head-free gaze trajectori...

journal_title：Journal of neurophysiology

authors： Martinez-Trujillo JC,Klier EM,Wang H,Crawford JD

更新日期：2003-10-01 00:00:00

abstract：:To explore a visual scene, the brain must detect an object of interest and direct the eyes to it. To investigate the brain's mechanism of saccade target selection, we trained monkeys to perform a visual search task with a response delay and recorded neuronal activity in the prefrontal (PF) cortex. Even though the monk...

journal_title：Journal of neurophysiology

authors： Hasegawa RP,Matsumoto M,Mikami A

更新日期：2000-09-01 00:00:00

abstract：:Nigrostriatal dopamine denervation plays a major role in basal ganglia circuitry disarray and motor abnormalities of Parkinson's disease (PD). Studies in rodent and primate models have revealed that striatal projection neurons, namely, medium spiny neurons (MSNs), increase the firing frequency. However, their activity...

journal_title：Journal of neurophysiology

authors： Singh A,Liang L,Kaneoke Y,Cao X,Papa SM

更新日期：2015-03-01 00:00:00

abstract：:Experimental evidence supports a number of mechanisms for the synaptic change that occurs with long-term potentiation (LTP) including insertion of AMPA receptors, an increase in AMPA receptor single channel conductance, unmasking silent synapses, and increases in vesicle release probability. Here we combine experiment...

journal_title：Journal of neurophysiology

authors： Holmes WR,Grover LM

更新日期：2006-09-01 00:00:00

abstract：:The hypothesis that gamma-band oscillations are related to the representation of an environmental scene in the cerebral cortex after binding of corresponding perceptual elements is currently under discussion. One question is how the sensory system reacts to a fast change in the scene if perceptual elements are rigidly...

journal_title：Journal of neurophysiology

authors： Ross B,Herdman AT,Pantev C

更新日期：2005-12-01 00:00:00

abstract：:1. The sensory responsiveness of cells in the inferior olive is known to be suppressed during certain phases of active movement. These experiments were designed to test the possibility that activity in the rubrospinal pathway contributes to this suppression. We recorded from cells sensitive to light touch located in o...

journal_title：Journal of neurophysiology

authors： Weiss C,Houk JC,Gibson AR

更新日期：1990-10-01 00:00:00

abstract：:Proteinase-activated receptors (PARs) have a unique activation mechanism in that a proteolytically exposed N-terminal region acts as a tethered ligand. A potential impact of PAR on sensory processing has not been fully examined yet. Here we report that synthetic peptides with sequences corresponding to PAR ligands enh...

journal_title：Journal of neurophysiology

authors： Fujita T,Liu T,Nakatsuka T,Kumamoto E

更新日期：2009-07-01 00:00:00

abstract：:It is well recognized that the brain uses sensory information to accurately produce motor commands. Indeed, most research into the relationship between sensory and motor systems has focused on how sensory information modulates motor function. In contrast, recent studies have begun to investigate the reverse: how senso...

journal_title：Journal of neurophysiology

authors： Wong JD,Wilson ET,Gribble PL

更新日期：2011-05-01 00:00:00

abstract：:1. Locusts use a distinctive motor pattern to extend the tibia of a hind leg rapidly in a defensive kick, or to extend the tibiae of both hind legs in a jump. The force for the movement is generated by an almost isometric co-contraction of the extensor and flexor tibiae muscles followed by a sudden release of the stor...

journal_title：Journal of neurophysiology

authors： Hedwig B,Burrows M

更新日期：1996-03-01 00:00:00

abstract：:Voluntary and stimulus-driven shifts of attention can modulate the representation of behaviorally relevant stimuli in early areas of visual cortex. In turn, attended items are processed faster and more accurately, facilitating the selection of appropriate behavioral responses. Information processing is also strongly i...

journal_title：Journal of neurophysiology

authors： Serences JT,Saproo S

更新日期：2010-07-01 00:00:00

abstract：:1. To characterize the temporal dynamic responses of ganglion cells and to define the possible inputs giving rise to their responses in catfish retina, we recorded the ganglion cell responses evoked by 1) a step of light presented in the dark, 2) an incremental and decremental step from a background illumination, and ...

journal_title：Journal of neurophysiology

authors： Sakai HM,Naka K

更新日期：1987-12-01 00:00:00

abstract：:Electrophysiological recordings show intense neuronal firing during epileptic seizures leading to enhanced energy consumption. However, the relationship between oxygen metabolism and seizure patterns has not been well studied. Recent studies have developed fast and quantitative techniques to measure oxygen microdomain...

journal_title：Journal of neurophysiology

authors： Wei Y,Ullah G,Ingram J,Schiff SJ

更新日期：2014-07-15 00:00:00

abstract：:Twenty-four slowly adapting type 1 (SA1) and 26 rapidly adapting (RA) cutaneous mechanoreceptive afferents in the rhesus monkey were studied with an array of independently controlled, punctate probes that covered an entire fingerpad. Each afferent had a receptive field (RF) on a single fingerpad and was studied at 73 ...

journal_title：Journal of neurophysiology

authors： Vega-Bermudez F,Johnson KO

更新日期：1999-06-01 00:00:00

abstract：:Pyramidal cells in the dorsal cochlear nucleus (DCN) show three characteristic discharge patterns in response tones: pauser, buildup, and regular firing. Experimental evidence suggests that a rapidly inactivating K+ current (I(KIF)) plays a critical role in generating these discharge patterns. To explore the role of I...

journal_title：Journal of neurophysiology

authors： Kanold PO,Manis PB

更新日期：2001-02-01 00:00:00

abstract：:This study aimed to determine whether individuals with spastic diplegic cerebral palsy (SDCP) have deficits in anticipatory inhibition of postural muscle activity. Nine individuals with SDCP (SDCP group, 3 female and 6 male, 13-24 yr of age) and nine age- and sex-matched individuals without disability (control group) ...

journal_title：Journal of neurophysiology

authors： Tomita H,Fukaya Y,Totsuka K,Tsukahara Y

更新日期：2013-04-01 00:00:00

abstract：:Transcranial DC stimulation (tDCS) induces stimulation polarity-dependent neuroplastic excitability shifts in the human brain. Because it accomplishes long-lasting effects and its application is simple, it is used increasingly. However, one drawback is its low focality, caused by 1) the large stimulation electrode and...

journal_title：Journal of neurophysiology

authors： Nitsche MA,Doemkes S,Karaköse T,Antal A,Liebetanz D,Lang N,Tergau F,Paulus W

更新日期：2007-04-01 00:00:00

abstract：:Neuron loss, axon sprouting, and the formation of new synaptic circuits have been hypothesized to contribute to seizures in temporal lobe epilepsy (TLE). Using the kainate-treated rat, we examined how alterations in the density of CA1 pyramidal cells and interneurons, and subsequent sprouting of CA1 pyramidal cell axo...

journal_title：Journal of neurophysiology

authors： Smith BN,Dudek FE

更新日期：2001-01-01 00:00:00

abstract：:Rod signals traverse several synapses en route to cone bipolar cells. In one pathway, rods communicate directly with cones via gap junctions. In a second pathway, signals flow rods-rod bipolars-AII amacrines-cone bipolars. The relative contribution of each pathway to retinal function is not well understood. Here we ha...

journal_title：Journal of neurophysiology

authors： Trexler EB,Li W,Massey SC

更新日期：2005-03-01 00:00:00

abstract：:Learning theories of drug addiction propose that the disorder is, at least in part, attributable to drug effects on accumbal mechanisms that are normally involved in reward-related learning. The neurophysiological mechanisms that might transduce such a drug effect on accumbal mechanisms have yet to be identified. Prev...

journal_title：Journal of neurophysiology

authors： Peoples LL,Cavanaugh D

更新日期：2003-08-01 00:00:00

abstract：:Results from previous studies suggest that two-dimensional spatial patterns are processed similarly in vision and touch when the patterns are equated for effective size or when visual stimuli are blurred to mimic the spatial filtering of the skin. In the present study, we measured subjects' ability to perceive the sha...

journal_title：Journal of neurophysiology

authors： Cho Y,Craig JC,Hsiao SS,Bensmaia SJ

更新日期：2016-01-01 00:00:00

abstract：:Whole cell and cell-attached patch-clamp techniques characterized the neurosteroid anesthetic alphaxalone's (5alpha-pregnane-3alpha-ol-11,20-dione) effects on GABAA receptors and on Cl- currents in cultured embryonic (5- to 8-wk old) human dorsal root ganglion neurons. Alphaxalone applied by pressure pulses from close...

journal_title：Journal of neurophysiology

authors： Valeyev AY,Hackman JC,Holohean AM,Wood PM,Katz JL,Davidoff RA

更新日期：1999-07-01 00:00:00

abstract：:In the oscillatory circuits known as central pattern generators (CPGs), most synaptic connections are inhibitory. We have assessed the effects of inhibitory synaptic input on the dynamic behavior of a component neuron of the pyloric CPG in the lobster stomatogastric ganglion. Experimental perturbations were applied to...

journal_title：Journal of neurophysiology

authors： Elson RC,Huerta R,Abarbanel HD,Rabinovich MI,Selverston AI

更新日期：1999-07-01 00:00:00

abstract：:Extracellular discharges from single neurons in the internal segment of the globus pallidus (GPi) were recorded and analyzed for rate changes associated with visually guided forearm rotations to four different targets. We sought to examine how GPi neurons contribute to movement preparation and execution. Unit discharg...

journal_title：Journal of neurophysiology

authors： Gdowski MJ,Miller LE,Parrish T,Nenonene EK,Houk JC

更新日期：2001-02-01 00:00:00

abstract：:The activity of the crayfish abdominal postural motoneurons and their associated neurons (the accessory neuron(s) and the MRO(1)) were examined with the aid of techniques for the analysis of simultaneously recorded spike trains. A means of reliably identifying the spikes of the individual motoneurons based on their re...

journal_title：Journal of neurophysiology

authors： Sokolove PG,Tatton WG

更新日期：1975-03-01 00:00:00

abstract：:PSD-95-like, disc-large (DLG) family membrane-associated guanylate kinase proteins (PSD/DLG-MAGUKs) are essential for regulating synaptic AMPA receptor (AMPAR) function and activity-dependent trafficking of AMPARs. Using a molecular replacement strategy to replace endogenous PSD-95 with SAP97β, we show that the protot...

journal_title：Journal of neurophysiology

authors： Liu M,Lewis LD,Shi R,Brown EN,Xu W

更新日期：2014-02-01 00:00:00

abstract：:Dorsal root afferent depolarization and antidromic firing were studied in isolated spinal cords of neonatal rats. Spontaneous firing accompanied by occasional bursts could be recorded from most dorsal roots in the majority of the cords. The afferent bursts were enhanced after elevation of the extracellular potassium c...

journal_title：Journal of neurophysiology

authors： Kremer E,Lev-Tov A

更新日期：1998-05-01 00:00:00

abstract：:Glutamatergic inputs clustered over approximately 20-40 microm can elicit local N-methyl-D-aspartate (NMDA) spike/plateau potentials in terminal dendrites of cortical pyramidal neurons, inspiring the notion that a single terminal dendrite can function as a decision-making computational subunit. A typical terminal basa...

journal_title：Journal of neurophysiology

authors： Major G,Polsky A,Denk W,Schiller J,Tank DW

更新日期：2008-05-01 00:00:00