Spatiotemporally graded NMDA spike/plateau potentials in basal dendrites of neocortical pyramidal neurons.

abstract：:Although understanding the processing of natural sounds is an important goal in auditory neuroscience, relatively little is known about the neural coding of these sounds. Recently we demonstrated that the spectral temporal receptive field (STRF), a description of the stimulus-response function of auditory neurons, cou...

journal_title：Journal of neurophysiology

authors： Sen K,Theunissen FE,Doupe AJ

更新日期：2001-09-01 00:00:00

abstract：:We analyzed the receptive field information conveyed by interspike intervals (ISIs) in the auditory cortex. In the visual system, different ISIs may both code for different visual features and convey differing amounts of stimulus information. To determine their potential role in auditory signal processing, we obtained...

journal_title：Journal of neurophysiology

authors： Shih JY,Atencio CA,Schreiner CE

更新日期：2011-04-01 00:00:00

abstract：:The mechanisms behind the therapeutic effects of electrical stimulation of the brain in epilepsy and other disorders are poorly understood. Previous studies in vitro have shown that uniform electric fields can suppress epileptiform activity through a direct polarizing effect on neuronal membranes. Such an effect depen...

journal_title：Journal of neurophysiology

authors： Mikkelsen R,Andreasen M,Nedergaard S

更新日期：2013-06-01 00:00:00

abstract：:Bis(7)-tacrine is a potent acetylcholinesterase inhibitor in which two tacrine molecules are linked by a heptylene chain. We tested the effects of bis(7)-tacrine on the spontaneous synaptic activity. Miniature endplate potentials (MEPPs) were recorded extracellularly on slices of electric organ of Torpedo marmorata. B...

journal_title：Journal of neurophysiology

authors： Ros E,Aleu J,Gomez de Aranda I,Cantí C,Pang YP,Marsal J,Solsona C

更新日期：2001-07-01 00:00:00

abstract：:1. The modulation of the voltage-activated Ca2+ current by the neuropeptide Phe-Met-Arg-Phe-NH2 (FMRFa) was investigated in dissociated central neurons from Helix aspersa using whole-cell voltage-clamp recording techniques. External Ba2+ was always used as the charge carrier in this study, and the intracellular Ca2+ c...

journal_title：Journal of neurophysiology

authors： Yakel JL

更新日期：1991-06-01 00:00:00

abstract：:A brain slice preparation from guinea pigs and intracellular recording techniques were used to examine the effects of carbachol application on the three classes (A, B, and C) of neurons (n = 68, 40 of class A, 12 of class B, 16 of class C) within the mediolateral part of the lateral septum (LSml). Bath application of ...

journal_title：Journal of neurophysiology

authors： Carette B

更新日期：1998-09-01 00:00:00

abstract：:Several previous studies have shown the existence of Up and Down states and have linked their magnitude (e.g., depolarization level) to the size of sensory-evoked responses. Here, we studied how the temporal dynamics of such states influence the sensory-evoked response to vibrissa deflection. Under alpha-chloralose an...

journal_title：Journal of neurophysiology

authors： Haslinger R,Ulbert I,Moore CI,Brown EN,Devor A

更新日期：2006-09-01 00:00:00

abstract：:Understanding how whisker-based tactile information is represented in the nervous system requires quantification of sensory input and observation of neural activity during whisking and whisker touch. Chronic electrophysiological methods have long been available to study neural responses in awake and behaving animals; ...

journal_title：Journal of neurophysiology

authors： Voigts J,Sakmann B,Celikel T

更新日期：2008-07-01 00:00:00

abstract：:1. The role of the microgeometry of planar surfaces in the detection of sliding of the surfaces on human and monkey fingerpads was investigated. By the use of a servo-controlled tactile stimulator to press and stroke glass plates on passive fingerpads of human subjects, the ability of humans to discriminate the direct...

journal_title：Journal of neurophysiology

authors： Srinivasan MA,Whitehouse JM,LaMotte RH

更新日期：1990-06-01 00:00:00

abstract：:1. The excitation of lumbar motoneurons by reticulospinal axons traveling in the medial longitudinal fasciculus (MLF) was investigated in the newborn rat using intracellular recordings from lumbar motoneurons in an in vitro preparation of the brain stem and spinal cord. The tracer DiI (1,1'-dioctadecyl-3,3,3',3'-tetra...

journal_title：Journal of neurophysiology

authors： Floeter MK,Lev-Tov A

更新日期：1993-12-01 00:00:00

abstract：:1. Outward currents in identified cell types from the pyloric system of the stomatogastric ganglion (STG) of the spiny lobster, Panulirus marginatus, were studied under two-microelectrode voltage clamp. A comparison was made between data from intact cells and somata isolated by ligation of the primary neurite of these...

journal_title：Journal of neurophysiology

authors： Hartline DK,Gassie DV,Jones BR

更新日期：1993-06-01 00:00:00

abstract：:The aim of this study was to examine the effects of kappa-opioid receptor selective agonists on responses of mechanosensitive afferent fibers in the pelvic nerve. Single-fiber recordings were made from pelvic nerve afferents in the decentralized S1 dorsal root of the rat. A total of 572 afferent fibers in the S1 dorsa...

journal_title：Journal of neurophysiology

authors： Su X,Sengupta JN,Gebhart GF

更新日期：1997-08-01 00:00:00

abstract：:Extensive work on learning in reaching and pointing tasks has demonstrated high degrees of plasticity in our ability to optimize goal-directed motor behavior. However, studies focusing on the perceptual awareness of our own actions during motor adaptation are still rare. Here we present the first simultaneous investig...

journal_title：Journal of neurophysiology

authors： Synofzik M,Thier P,Lindner A

更新日期：2006-09-01 00:00:00

abstract：:Previous functional MRI studies reported neural correlates of risk and ambiguity based on behavioral economic theories. A recent study controlled for uncertainty by adding noise to information of an impending aversive event and demonstrated brain areas that did not track the degree of uncertainty: the activation peake...

journal_title：Journal of neurophysiology

authors： O'Neill M,Kobayashi S

更新日期：2009-08-01 00:00:00

abstract：:1. Responses to innocuous and noxious mechanical and thermal stimuli were recorded from 90 neurons in the gracile nucleus of anesthetized cats. Cells were tested by antidromic activation for projections to the contralateral ventrobasal thalamus. 2. Cells were characterized broadly by their responses to mechanical stim...

journal_title：Journal of neurophysiology

authors： Cliffer KD,Hasegawa T,Willis WD

更新日期：1992-09-01 00:00:00

abstract：:Human languages can express opposite propositions by means of the negative operator "not," which turns affirmative sentences into negative ones. Psycholinguistic research has indicated that negative meanings are formed by transiently reducing the access to mental representations of negated conceptual information. Neur...

journal_title：Journal of neurophysiology

authors： Bartoli E,Tettamanti A,Farronato P,Caporizzo A,Moro A,Gatti R,Perani D,Tettamanti M

更新日期：2013-04-01 00:00:00

abstract：:The purpose of these studies was to determine the role of gracile nucleus and the effects of l-arginine-derived nitric oxide (NO) synthesis in the nucleus on the cardiovascular responses to electroacupuncture (EA) stimulation of "Zusanli" (ST36). Arterial blood pressure and heart rate were monitored during EA stimulat...

journal_title：Journal of neurophysiology

authors： Chen S,Ma SX

更新日期：2003-08-01 00:00:00

abstract：:Smooth pursuit eye movements stabilize slow-moving objects on the retina by matching eye velocity with target velocity. Two critical components are required to generate smooth pursuit: first, because it is a voluntary eye movement, the subject must select a target to pursue to engage the tracking system; and second, g...

journal_title：Journal of neurophysiology

authors： Mitchell JF,Priebe NJ,Miller CT

更新日期：2015-06-01 00:00:00

abstract：:The motor pathway responsible for the complex vocalizations of songbirds has been extensively characterized, both in terms of intrinsic and synaptic physiology in vitro and in terms of the spatiotemporal patterns of neural activity in vivo. However, the relationship between the neural architecture of the song motor pa...

journal_title：Journal of neurophysiology

authors： Abarbanel HD,Gibb L,Mindlin GB,Talathi S

更新日期：2004-07-01 00:00:00

abstract：:1. Single motor axons innervating human toe extensor muscles were selectively stimulated through a tungsten microelectrode inserted percutaneously into the peroneal nerve. Twitch and tetanic forces were measured from a strain gauge over the proximal phalanx of the toe generating the greatest force. Twitch data were ob...

journal_title：Journal of neurophysiology

authors： Macefield VG,Fuglevand AJ,Bigland-Ritchie B

更新日期：1996-06-01 00:00:00

abstract：:A popular theory is that the cerebellum functions as a timer for clocking motor events (e.g., initiation, termination). Consistent with this idea, cerebellar patients have been reported to show greater deficits during hand movements that repeatedly start and stop (i.e., discontinuous movements) compared with continuou...

journal_title：Journal of neurophysiology

authors： Bo J,Block HJ,Clark JE,Bastian AJ

更新日期：2008-11-01 00:00:00

abstract：:1. We examined excitation and the facilitatory effect on the heat responses induced by histamine in visceral polymodal receptors with the use of the canine testis-spermatic nerve preparation in vitro. 2. The proportion of units that showed excitation (> 10 impulses 1 min after application of histamine was initiated) i...

journal_title：Journal of neurophysiology

authors： Koda H,Minagawa M,Si-Hong L,Mizumura K,Kumazawa T

更新日期：1996-09-01 00:00:00

abstract：:Head rotation, translation, and tilt with respect to a gravitational field elicit reflexive eye movements that partially stabilize images of Earth-fixed objects on the retinas of humans and other vertebrates. Compared with the angular vestibulo-ocular reflex, responses to translation and tilt, collectively called the ...

journal_title：Journal of neurophysiology

authors： Hageman KN,Chow MR,Roberts D,Della Santina CC

更新日期：2020-01-01 00:00:00

abstract：:Operant conditioning was used to train cats with their heads immobilized to localize sound by directing their eyes to the location of the sources. The kinematics of those eye movements were studied and compared with eye movements to visual targets at the same locations. The main finding of this study is that eye movem...

journal_title：Journal of neurophysiology

authors： Populin LC,Yin TC

更新日期：1999-08-01 00:00:00

abstract：:Activation of calcium-calmodulin dependent protein kinase II (CaMKII) during induction of long-term potentiation (LTP) is a series of complicated stochastic processes that are affected by noise. There are two main sources of noise affecting CaMKII activation within a dendritic spine. One is the noise associated with s...

journal_title：Journal of neurophysiology

authors： Zeng S,Holmes WR

更新日期：2010-04-01 00:00:00

abstract：:For primary auditory cortex (AI) laminae, there is little evidence of functional specificity despite clearly expressed cellular and connectional differences. Natural sounds are dominated by dynamic temporal and spectral modulations and we used these properties to evaluate local functional differences or constancies ac...

journal_title：Journal of neurophysiology

authors： Atencio CA,Schreiner CE

更新日期：2010-01-01 00:00:00

abstract：:Caenorhabditis elegans responds to chemical cues using a small number of chemosensory neurons that detect a large variety of molecules in its environment. During chemotaxis, C. elegans biases its migration in spatial chemical gradients by lengthening (/shortening) periods of forward movement when it happens to be movi...

journal_title：Journal of neurophysiology

authors： Luo L,Gabel CV,Ha HI,Zhang Y,Samuel AD

更新日期：2008-05-01 00:00:00

abstract：:1. To analyze further the sensory mechanisms for triggering the lordosis reflex, single-unit (n = 345) activity was recorded extracellularly from spinal segments L5-S1 of urethan-anesthetized female rats. Unit responses to pressure on the skin (necessary and sufficient for evoking lordosis) and other mechanical stimul...

journal_title：Journal of neurophysiology

authors： Kow LM,Zemlan FP,Pfaff DW

更新日期：1980-01-01 00:00:00

abstract：:For the first time in any vertebrate, in vivo responses of single olfactory receptor neurons to odorant mixtures were studied quantitatively. Extracellular electrophysiological response of 54 single olfactory receptor neurons from 23 channel catfish, Ictalurus punctatus, to binary mixtures of amino acids and to their ...

journal_title：Journal of neurophysiology

authors： Kang J,Caprio J

更新日期：1997-01-01 00:00:00

abstract：:Population spikes vary in size during prolonged epileptic ("ictal") discharges, indicating variations in neuronal synchronization. Here we investigate the role of changes in tissue electrical resistivity in this process. We used the rat hippocampal slice, low-Ca(2+) model of epilepsy and measured changes in pyramidal ...

journal_title：Journal of neurophysiology

authors： Fox JE,Bikson M,Jefferys JG

更新日期：2004-07-01 00:00:00