Abstract:
:The response properties of ampullary electroreceptors of paddlefish, Polyodon spathula, were studied in vivo, as single-unit afferent responses to external electrical stimulation with varied intensities of several types of noise waveforms, all Gaussian and zero-mean. They included broadband white noise, Ornstein-Uhlenbeck noise, low- or high-frequency band-limited noise, or natural noise recorded from swarms of Daphnia zooplankton prey, or from individual prey. Normally the afferents fire spontaneously in a tonic manner, which is actually quasiperiodic due to embedded oscillators. 1) Weak noise stimuli increased the variability of afferent firing, but it remained tonic. 2) In contrast, stimulation with less-weak broadband noise led to a qualitative change of the firing patterns, to parabolic bursting, even though the mean firing rate was scarcely affected. 3) The transition to afferent bursting was marked by the development of two well-separated timescales: the fast frequency of spiking inside bursts at journal_name journal_title authors doi subject pub_date pages issue eissn issn pii journal_volume pub_type
abstract::The lateral hypothalamus (LH), which plays a role in homeostatic functions such as appetite regulation, is also linked to arousal and motivational behavior. However, little is known about how these components are encoded in the LH. Thus cynomolgus monkeys were conditioned with two distinct contexts, i.e., an appetitiv...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00247.2018
更新日期:2019-02-01 00:00:00
abstract::Anatomical and physiological data have implicated the pretectal olivary nucleus (PON) as the midbrain relay for the pupillary light reflex in a variety of species. To determine the nature of the discharge of pretectal light reflex relay neurons, we recorded their activity in monkeys that were fixating a stationary spo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2000.84.2.964
更新日期:2000-08-01 00:00:00
abstract::We investigated behavior, physiology, sensitivity to exogenous application of ecdysone, and nerve terminal structure for differences between the reduced ecdysone genotype, ecd(1)/ecd(1), and wild-type control ecd(1)/TM6B animals during the early and late third instars when raised at 25 degrees C. The ecd(1) mutants we...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.85.1.98
更新日期:2001-01-01 00:00:00
abstract::This study investigated how the ability to extend the fingers and thumb recovers early after stroke and how the ability to extend all of the digits affects grasping performance. We studied 24 hemiparetic patients at 3 and 13 wk post stroke. At each visit, we tested the subjects' ability to actively extend all five dig...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.91310.2008
更新日期:2009-07-01 00:00:00
abstract::Many single-unit electrophysiological studies of visual cortex have investigated strong evoked responses to simple stimuli such as oriented gratings. Experiments involving other types of stimuli, such as natural scenes, higher-order features, and surface brightness, produce single-unit responses that are more difficul...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00420.2001
更新日期:2002-05-01 00:00:00
abstract::1. The effect of cholinergic receptor activation on gamma-aminobutyric acid (GABA)-mediated inhibitory synaptic transmission was investigated in voltage-clamped CA1 pyramidal neurons (HPNs) in the guinea pig hippocampal slice preparation. 2. The cholinergic agonist carbachol (1-10 microM) induced a prominent and susta...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1993.69.2.626
更新日期:1993-02-01 00:00:00
abstract::A new method is presented based on trinary logic able to check the state of different control variables and synchronously record the physiological and behavioral data of behaving animals and humans. The basic information structure of the method is a time interval of defined maximum duration, called time slice, during ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01292.2004
更新日期:2005-06-01 00:00:00
abstract::1. The fast extensor tibiae motor neuron makes direct excitatory central connections with the posterior group of flexor tibiae motor neurons in the locust metathoracic ganglion. The flexor group has a slow, a fast, and an intermediate motor neuron. The motor neurons are involved in the motor program for kicking and ju...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1995.74.2.529
更新日期:1995-08-01 00:00:00
abstract::The ovulation hormone-producing caudodorsal cells (CDCs) of the pond snail Lymnaea stagnalis form two clusters of electrotonically coupled cells, each containing a few specialized (ventral) cells that connect the clusters. The hormone is secreted during a pacemaker-driven discharge. The CDCs receive a biphasic choline...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1983.49.6.1392
更新日期:1983-06-01 00:00:00
abstract::1. Semi-isolated preparations of the nine-celled cardiac ganglion of the crab, Portunus sanguinolentus, were studied electrophysiologically, using simultaneous recording from extracellular and two or three intracellular electrodes. Nine penetrations of small cells were achieved. 2. Three large (80 x 120 micron) cells ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1979.42.4.975
更新日期:1979-07-01 00:00:00
abstract::1. We study the propagation and dynamics of spindle waves in thalamic slices by developing and analyzing a model of reciprocally coupled populations of excitatory thalamocortical (TC) neurons and inhibitory thalamic reticular (RE) neurons. 2. Each TC neuron has three intrinsic ionic currents: a low-threshold T-type Ca...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1996.75.2.750
更新日期:1996-02-01 00:00:00
abstract::1. A compartmental model was employed to investigate the electrical behavior of a dendritic spine having excitable membrane at the spine head. Here we used the Hodgkin and Huxley equations to generate excitable membrane properties; in some cases the kinetics were modified to get a longer duration action potential. Pas...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1988.60.2.499
更新日期:1988-08-01 00:00:00
abstract::In layer 2/3 of neocortex, brief trains of action potentials in pyramidal neurons (PNs) induce the mobilization of endogenous cannabinoids (eCBs), resulting in a depression of GABA release from the terminals of inhibitory interneurons (INs). This depolarization-induced suppression of inhibition (DSI) is mediated by ac...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00817.2007
更新日期:2007-11-01 00:00:00
abstract::Control of myoelectric prostheses and brain-machine interfaces requires learning abstract neuromotor transformations. To investigate the mechanisms underlying this ability, we trained subjects to move a two-dimensional cursor using a myoelectric-controlled interface. With the upper limb immobilized, an electromyogram ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.90614.2008
更新日期:2008-10-01 00:00:00
abstract::Previous studies have shown that intracortical inhibition (ICI) plays an important role in shaping the output from primary motor cortex (M1). This study explored the muscle specificity and temporal modulation of ICI during the performance of a phasic index finger flexion task. Fifteen subjects were asked to rest their...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00925.2002
更新日期:2003-04-01 00:00:00
abstract::We investigated whether heptanol and other long-chain alcohols that are known to block gap junctions interfere with the generation or the propagation of spreading depression (SD). Waves of SD were triggered by micro-injection of concentrated KCl solution in stratum (s.) radiatum of CA1 of rat hippocampal tissue slices...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1997.77.1.9
更新日期:1997-01-01 00:00:00
abstract::Voltage-activated currents in blue cones of the retinal slice of zebrafish were characterized using whole cell recording techniques. Depolarizing-elicited currents were recorded: an outward tetraethylammonium (TEA)-sensitive K+ current (IKx), an outward Ca(2+)-activated Cl- current (ICl(Ca)), from which we inferred an...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1997.77.3.1447
更新日期:1997-03-01 00:00:00
abstract::The ventrolateral preoptic nucleus (VLPO) is a key nucleus involved in the homeostatic regulation of sleep-wakefulness. Little is known, however, about the cellular mechanisms underlying its role in sleep regulation and how the neurotransmitters, such as GABA and noradrenaline (NA), are involved. In the present study ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00491.2002
更新日期:2003-03-01 00:00:00
abstract::The pacemaker current of a bursting neuron of Helix pomatia was investigated using voltage-clamp and pressure-injection techniques. In the steady state the net membrane current was zero near threshold of the action potential at -45 mV. Negative to this potential the membrane current was inward and steady. During burst...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1985.54.6.1430
更新日期:1985-12-01 00:00:00
abstract::Although studies of the principal tongue protrudor muscle genioglossus (GG) suggest that whole muscle GG electromyographic (EMG) activities are preserved in nonrapid eye movement (NREM) sleep, it is unclear what influence sleep exerts on individual GG motor unit (MU) activities. We characterized the firing patterns of...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00865.2007
更新日期:2007-12-01 00:00:00
abstract::The vestibular system plays a critical role in detection of head movements and is essential for normal postural control. Because of their anatomical proximity to the cochlea, the otolith organs are selectively exposed to sound pressure and are at risk for noise overstimulation. Clinical reports suggest a link between ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00668.2017
更新日期:2018-02-01 00:00:00
abstract::Whole cell patch-clamp recordings were used to investigate the contribution of transient, low-threshold calcium currents (I(T)) to firing properties of hamster spinal dorsal horn neurons. I(T) was widely, though not uniformly, expressed by cells in Rexed's laminae I-IV and correlated with the pattern of action potenti...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.01083.2010
更新日期:2011-11-01 00:00:00
abstract::Traumatic brain injury (TBI) is one of the most common neurological disorders causing memory reduction, particularly short-term memory (STM). We showed that, during TBI-induced inflammation, increased blood content of fibrinogen (Fg) enhanced vascular protein transcytosis and deposition of extravasated Fg in vasculo-a...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00224.2020
更新日期:2020-08-01 00:00:00
abstract::The responses of cortical neurons to repeated presentation of a stimulus are highly variable, yet correlated. These "noise correlations" reflect a low-dimensional structure of population dynamics. Here, we examine noise correlations in 22,705 pairs of neurons in primary visual cortex (V1) of anesthetized cats, during ...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00094.2015
更新日期:2015-08-01 00:00:00
abstract::The responses of spinothalamic tract neurons were studied by extra- and intracellular recordings from the lumbosacral spinal cord in anesthetized rhesus monkeys (Macaca mulatta). The neurons were identified by antidromic activation from the contralateral diencephalon. They were then classified by the mildest form of m...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1975.38.1.132
更新日期:1975-01-01 00:00:00
abstract::The corticospinal tract excitability is modulated when preparing movements. Earlier to movement execution, the excitability of the spinal cord increases waiting for supraspinal commands to release the movement. Movement execution and movement observation share processes within the motor system, although movement obser...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00353.2013
更新日期:2014-04-01 00:00:00
abstract::We propose that the descending command from area 4 that is responsible, in part, for the change in limb trajectory required to step over an obstacle in one's path also plays a role in triggering the anticipatory postural modifications that accompany this movement. To test this hypothesis, we recorded the discharge cha...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1998.80.1.406
更新日期:1998-07-01 00:00:00
abstract::Neuron loss, axon sprouting, and the formation of new synaptic circuits have been hypothesized to contribute to seizures in temporal lobe epilepsy (TLE). Using the kainate-treated rat, we examined how alterations in the density of CA1 pyramidal cells and interneurons, and subsequent sprouting of CA1 pyramidal cell axo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.2001.85.1.1
更新日期:2001-01-01 00:00:00
abstract::During priming of pop-out, performance at discriminating a pop-out feature target in visual search is affected by whether the target on the previous trial was defined by the same feature as on the upcoming trial. Recent studies suggest that priming of pop-out relies on attentional processes. With the use of simultaneo...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.00121.2011
更新日期:2011-12-01 00:00:00
abstract::Calcium ions are known to play an important role in epileptogenesis. Although there is clear evidence for increased neuronal calcium influx during epileptiform potentials, direct measurements of the corresponding intracellular calcium transients are rare and the origin of calcium influx is not known. Therefore the spa...
journal_title:Journal of neurophysiology
pub_type: 杂志文章
doi:10.1152/jn.1997.77.1.491
更新日期:1997-01-01 00:00:00