Responses of primate spinothalamic tract neurons to electrical stimulation of hindlimb peripheral nerves.

abstract：:Receptive fields of neurons in somatosensory area 3b of monkeys are typically described as restricted to part of a single digit or palm pad. However, such neurons are likely involved in integrating stimulus information from across the hand. To evaluate this possibility, we recorded from area 3b neurons in anesthetized...

journal_title：Journal of neurophysiology

authors： Reed JL,Qi HX,Zhou Z,Bernard MR,Burish MJ,Bonds AB,Kaas JH

更新日期：2010-04-01 00:00:00

abstract：:The gain of the vertical vestibuloocular reflex (VVOR), defined as eye velocity/head velocity was adapted in squirrel monkeys by employing visual-vestibular mismatch stimuli. VVOR gain, measured in the dark, could be trained to values between 0.4 and 1.5. Single-unit activity of vertical zone Purkinje cells was record...

journal_title：Journal of neurophysiology

authors： Hirata Y,Highstein SM

更新日期：2001-05-01 00:00:00

abstract：:1. The question of whether active uptake limits the duration of action of the inhibitory transmitter glycine has been addressed in vivo at inhibitory synapses on the goldfish Mauthner (M) cell. The kinetics of inhibitory postsynaptic potentials and inhibitory postsynaptic currents (IPSCs) evoked antidromically and by ...

journal_title：Journal of neurophysiology

authors： Titmus MJ,Korn H,Faber DS

更新日期：1996-04-01 00:00:00

abstract：:Although metabotropic glutamate receptors (mGluRs) mGluR1 and mGluR5 are often found to have similar functions, there is considerable evidence that the two receptors also serve distinct functions in neurons. In hippocampal area CA1, mGluR5 has been most strongly implicated in long-term synaptic depression (LTD), where...

journal_title：Journal of neurophysiology

authors： Volk LJ,Daly CA,Huber KM

更新日期：2006-04-01 00:00:00

abstract：:Two-Photon Processor (TPP) is a versatile, ready-to-use, and freely available software package in MATLAB to process data from in vivo two-photon calcium imaging. TPP includes routines to search for cell bodies in full-frame (Search for Neural Cells Accelerated; SeNeCA) and line-scan acquisition, routines for calcium s...

journal_title：Journal of neurophysiology

authors： Tomek J,Novak O,Syka J

更新日期：2013-07-01 00:00:00

abstract：:1. Effects of substance P (SP) and other tachykinins on membrane currents were investigated using whole cell voltage clamp in cultured sensory neurons isolated from rat dorsal root ganglia. 2. SP (100 nM) evoked an inward current in two-thirds of the cells at negative potentials. In most of the cells that generated th...

journal_title：Journal of neurophysiology

authors： Inoue K,Nakazawa K,Inoue K,Fujimori K

更新日期：1995-02-01 00:00:00

abstract：:Outward K+ currents were recorded using a whole cell patch-clamp configuration, from acutely dissociated adult rat cutaneous afferent dorsal root ganglion (DRG) neurons (L4 and L5) identified by retrograde labeling with Fluoro-gold. Recordings were obtained 16-24 h after dissociation from cells between 39 and 49 mm in...

journal_title：Journal of neurophysiology

authors： Everill B,Rizzo MA,Kocsis JD

更新日期：1998-04-01 00:00:00

abstract：:Secondary hyperalgesia is believed to be a key feature of "central sensitization" and is characterized by enhanced pain to mechanical nociceptive stimuli. The aim of the present study was to characterize, using EEG, the effects of pinprick stimulation intensity on the magnitude of pinprick-elicited brain potentials [e...

journal_title：Journal of neurophysiology

authors： van den Broeke EN,Mouraux A,Groneberg AH,Pfau DB,Treede RD,Klein T

更新日期：2015-11-01 00:00:00

abstract：:1. In chronically prepared, freely moving rats, electrical stimulation was applied to the angular bundle, and responses were recorded extracellularly at a variety of sites in the ipsilateral hippocampal formation. At each recording site the stimulus-response relationship was tested during four different behavioral sta...

journal_title：Journal of neurophysiology

authors： Winson J,Abzug C

更新日期：1978-05-01 00:00:00

abstract：:Experimental evidence supports a number of mechanisms for the synaptic change that occurs with long-term potentiation (LTP) including insertion of AMPA receptors, an increase in AMPA receptor single channel conductance, unmasking silent synapses, and increases in vesicle release probability. Here we combine experiment...

journal_title：Journal of neurophysiology

authors： Holmes WR,Grover LM

更新日期：2006-09-01 00:00:00

abstract：:1. Fluorescence changes in the dye di-4-ANEPPS were monitored on the rat's nasal septum and medial surface of the turbinates in response to odorant stimuli. For each mucosal surface a 6.0 x 6.0-mm area was sampled at 100 contiguous sites with a 10 x 10 photodiode array. The odorants were propyl acetate, 2-propanol, ci...

journal_title：Journal of neurophysiology

authors： Youngentob SL,Kent PF,Sheehe PR,Schwob JE,Tzoumaka E

更新日期：1995-01-01 00:00:00

abstract：:Contrasting theories of visual attention have emphasized selection by spatial location, individual features, and whole objects. We used functional magnetic resonance imaging to ask whether and how attention to one feature of an object spreads to other features of the same object. Subjects viewed two spatially superimp...

journal_title：Journal of neurophysiology

authors： Ernst ZR,Boynton GM,Jazayeri M

更新日期：2013-11-01 00:00:00

abstract：:In developing ciliary ganglion (CG) neurons, movement of functional large-conductance (BK type) Ca(2+)-activated K+ (K(Ca)) channels to the cell surface is stimulated by the endogenous growth factors TGF(beta)1 and beta-neuregulin-1 (NRG1). Here we show that a brief NRG1 treatment (0.5-1.5 h) mobilizes K(Ca) channels ...

journal_title：Journal of neurophysiology

authors： Chae KS,Oh KS,Dryer SE

更新日期：2005-08-01 00:00:00

abstract：:Responses to tones, clicks, and noise were recorded from chinchilla auditory-nerve fibers (ANFs). The responses to noise were analyzed by computing the zeroth-, first-, and second-order Wiener kernels (h0, h1, and h2). The h1s correctly predicted the frequency tuning and phases of responses to tones of ANFs with low c...

journal_title：Journal of neurophysiology

authors： Temchin AN,Recio-Spinoso A,van Dijk P,Ruggero MA

更新日期：2005-06-01 00:00:00

abstract：:1. A task was used by Posner (1980) to measure shifts of attention that occurred covertly, in the absence of an eye movement or other orienting response. This paradigm was used here to assess the nature of covert attentional orienting in monkeys to develop an animal model for neurophysiological studies. Shifts of atte...

journal_title：Journal of neurophysiology

authors： Bowman EM,Brown VJ,Kertzman C,Schwarz U,Robinson DL

更新日期：1993-07-01 00:00:00

abstract：:1. The extracellular activity of 45 antidromically identified spinocervical tract (SCT) neurons responsive to light mechanical stimulation of the glabrous surfaces of the forepaw was examined in raccoons anesthetized with pentobarbital sodium. An additional seven neurons had peripheral receptive fields (RFs) located o...

journal_title：Journal of neurophysiology

authors： Hirata H,Pubols BH Jr

更新日期：1989-01-01 00:00:00

abstract：:GSG1L is an AMPA receptor (AMPAR) auxiliary subunit that regulates AMPAR trafficking and function in hippocampal CA1 pyramidal neurons. However, its physiological roles in other types of neurons remain to be characterized. Here, we investigated the role of GSG1L in hippocampal dentate granule cells and found that GSG1...

journal_title：Journal of neurophysiology

authors： Mao X,Gu X,Lu W

更新日期：2017-01-01 00:00:00

abstract：:Acetylcholine increases intracellular calcium of arterial chemoreceptor cells of adult cats. J. Neurophysiol. 78: 2388-2395, 1997. Several neurotransmitters have been reported to play important roles in the chemoreception of the carotid body. Among them acetylcholine (ACh) appears to be involved in excitatory processe...

journal_title：Journal of neurophysiology

authors： Shirahata M,Fitzgerald RS,Sham JS

更新日期：1997-11-01 00:00:00

abstract：:1. Many cells in the superior temporal sulcus (STS) of the monkey that represent the foveal region of the visual field discharge during pursuit eye movements. Damage to these areas produces a deficit in the maintenance of pursuit eye movements when the target towards the side of the brain with the lesion. In the prese...

journal_title：Journal of neurophysiology

authors： Komatsu H,Wurtz RH

更新日期：1989-07-01 00:00:00

abstract：:1. This paper reports the results of an investigation of the basic mechanisms underlying intersegmental coordination in lamprey locomotion, by the use of a combined mathematical and biological approach. 2. Mathematically, the lamprey central pattern generator (CPG) is described as a chain of coupled nonlinear oscillat...

journal_title：Journal of neurophysiology

authors： Williams TL,Sigvardt KA,Kopell N,Ermentrout GB,Remler MP

更新日期：1990-09-01 00:00:00

abstract：:The input-output and discharge properties of neurons are shaped by both passive and active electrophysiological membrane properties. Whole cell patch-clamp recordings in lamina I-III neurons in an isolated preparation of the whole spinal cord of juvenile rats with attached dorsal roots and dorsal root ganglia were use...

journal_title：Journal of neurophysiology

authors： Dougherty PM,Chen J

更新日期：2016-09-01 00:00:00

abstract：:Slowness of voluntary movements in patients with multiple sclerosis (MS) may be due to various factors, including attentional and cognitive deficits, delays in motor conduction time, and impairment of specific central nervous system circuits. In 13 healthy volunteers and 20 mildly disabled, relapsing-remitting MS pati...

journal_title：Journal of neurophysiology

authors： Cabib C,Llufriu S,Casanova-Molla J,Saiz A,Valls-Solé J

更新日期：2015-03-01 00:00:00

abstract：:Rodents shift their nose from side to side when they actively explore and lateralize odors in the space. This motor action is driven by a pair of muscles, the deflector nasi. We studied the premotor control of this motion. We used replication-competent rabies virus to transsynaptically label inputs to the deflector na...

journal_title：Journal of neurophysiology

authors： Kurnikova A,Deschênes M,Kleinfeld D

更新日期：2019-01-01 00:00:00

abstract：:Modulation of sacral spinal dorsal horn neurons by the ventrolateral PAG was studied by extracellular recording combined with microiontophoretic applications of alpha-adrenergic agonists or antagonists. Bicuculline (BIC, 15 ng) microinjected into the ventrolateral PAG produced a consistent inhibition of the responses ...

journal_title：Journal of neurophysiology

authors： Budai D,Harasawa I,Fields HL

更新日期：1998-11-01 00:00:00

abstract：:The development of synaptic interconnections between the cerebellum and inferior olive, the sole source of climbing fibers, could contribute to the ontogeny of certain forms of motor learning (e.g., eyeblink conditioning). Purkinje cell complex spikes are produced exclusively by climbing fibers and exhibit short- and ...

journal_title：Journal of neurophysiology

authors： Nicholson DA,Freeman JH Jr

更新日期：2003-10-01 00:00:00

abstract：:The amygdala plays a crucial role in evaluating the emotional significance of stimuli and in transforming the results of this evaluation into appropriate autonomic responses. Lesion and stimulation studies suggest involvement of the amygdala in the generation of the skin conductance response (SCR), which is an indirec...

journal_title：Journal of neurophysiology

authors： Laine CM,Spitler KM,Mosher CP,Gothard KM

更新日期：2009-04-01 00:00:00

abstract：:1. Effects of hypothalamic stimulation on activity of dorsomedial medulla neurons that responded to subdiaphragmatic vagal stimulation were investigated in urethan-anesthetized rats. 2. Extracellular recordings were made from 231 neurons in the nucleus of the tractus solitarius (NTS) that fired repetitively in respons...

journal_title：Journal of neurophysiology

authors： Nishimura H,Oomura Y

更新日期：1987-10-01 00:00:00

abstract：:The exercise pressor reflex, a crucial component of the cardiovascular response under physiological and pathophysiological states, is activated via metabolic and mechanical mediators that originate from contracting muscles and stimulate group III and IV afferents. We reported previously that stimulation of mu opioid r...

journal_title：Journal of neurophysiology

authors： Hassan B,Kim JS,Farrag M,Kaufman MP,Ruiz-Velasco V

更新日期：2014-12-15 00:00:00

abstract：:We cloned 10 full-length variants of PIIH, the gene for I(h) from the spiny lobster, Panulirus interruptus, using reverse transcription-PCR (RT-PCR) and rapid amplification of cDNA ends (RACE). This gene shows a significant amount of alternative splicing in the S3-S4 and S4-S5 linkers, in the P-loop and the entire S6 ...

journal_title：Journal of neurophysiology

authors： Ouyang Q,Goeritz M,Harris-Warrick RM

更新日期：2007-06-01 00:00:00

abstract：:In this study, the juxtamembrane region of the Drosophila SNARE protein neuronal-Synaptobrevin (n-Syb) was tested for its role in synaptic transmission. A transgenic approach was used to express n-Syb mutant genes. The transgenes carried engineered point mutations that alter the amino acid sequence of the conserved tr...

journal_title：Journal of neurophysiology

authors： DeMill CM,Qiu X,Kisiel M,Bolotta A,Stewart BA

更新日期：2014-09-15 00:00:00